Neoclerodanes from Teucrium orientale

Two new neoclerodane diterpenoids, 6-deacetyl-teucrolivin A (5) and 8beta-hydroxy-teucrolivin B (6), were isolated from the aerial parts of Teucrium orientale, along with four already known neoclerodane diterpenoids, teucrolivin A (1), teucrolivin B (2), teucrolivin C (3) and teucrolivin H (4), previously isolated from Teucrium oliverianum. Their structures were elucidated on the basis of spectroscopic evidence and chemical transformations. Compounds 1-3 were assayed for antifeedant activity against Spodoptera littoralis, S. frugiperda and Heliocoverpa armigera. Teucrolivin A was the most potent of the three compounds tested.     

A New Triterpenoid from Teucrium Integrifolium

IncontinuationofourstudiesonbiologicallyactiveprinciplesfromTeucriumspecies"',wehaveinvestigatedTintegrifoliumC.Y.Wuetal,whichwascollectedinShibingcounty,GuizhouprovinceofChinaandwasusedforthetreatmentofswordwoundsandtostopbleedinginfolkmedicine3.AnalysisoftheEtOAc-solublepartoftheextractoftheaerialpartshasledtotheisolationofonenewtriterpenoid1,withtheknownhydrocarbonpentatriacontane.Inthispaper,wereportonthestructuralelucidationofthenewcompound1-Compound1,mp3l5.5-3l6.5"C,[a]:-2l.5(cO.23,…     

A New Irregular Trihydroxy Sesquiterpene from Teucrium mascatense

A new trihydroxy sesquiterpene, rel‐(1R,4aR,5S,6S,7S,8aR)‐decahydro‐6,8a‐dimethyl‐5‐(propan‐2‐yl)naphthalene‐1,6,7‐triol ( 1 ), has been isolated as a result of the phytochemical investigation on the CH₂Cl₂ extract of Teucrium mascatense. The structure elucidation of the new constituent was carried out by the combined use of 1D‐ (¹H‐ and ¹³C‐NMR) and 2D‐NMR (HMBC and HSQC) spectroscopic analysis, along with mass spectrometric techniques. In addition to the new constituent 1 , the known metabolite 2 , previously isolated from Crataegus pinnatifida, was also identified.     

铁轴草中Teucvidin的衍生物研究

从唇形科植物铁轴草中分离得去甲克罗烷二萜化合物Ｔｅｕｃｖｉｄｉｎ，通过催化氢化、酯交换、水解等反应合成了８个衍生物，用＾１ＨＮＭＲ、ＭＳ和ＩＲ确定了其结构，初步生物活性测定结果表明，化合物Ⅱ和Ⅳａ的拒食作用显著。     

Chemical Composition of Essential Oils from Hedyosmum orientale

Chemistry of Natural Compounds -     

Structures of two new diterpenoids from Teucrium polium

Two new acids of the neoclerodane series have been isolated fromTeucrium polium L. (Lamiaceae); they have been called tepolin A and tepolin B and their structures have been established on the basis of spectral characteristics as 7,12,19-trihydroxy-6,18:15,16-diepoxycleroda-3,13(16),14-triene-9-carboxylic acid and 12,19-dihydroxy-6,18:15,16-diepoxycleroda-3,13(16)-14-triene-9-carboxylic acid, respectively. Institute of Fine Organic Chemistry, Armenian Academy of Sciences, Erevan. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 503–508, September–October, 1992.     

Structures of two new diterpenoids from Teucrium polium

Two new acids of the neoclerodane series have been isolated fromTeucrium polium L. (Lamiaceae); they have been called tepolin A and tepolin B and their structures have been established on the basis of spectral characteristics as 7,12,19-trihydroxy-6,18:15,16-diepoxycleroda-3,13(16),14-triene-9-carboxylic acid and 12,19-dihydroxy-6,18:15,16-diepoxycleroda-3,13(16)-14-triene-9-carboxylic acid, respectively.Institute of Fine Organic Chemistry, Armenian Academy of Sciences, Erevan. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 503–508, September–October, 1992.     

Alkaloids ofPapaver orientale

Continuing the separation of the total alkaloids of the plantPapaver orientale L., collected in the flowering phase in the region of Lake Sevan, orientalidine, mecambridine, isothebaine, and bracteoline have been isolated, together with new alkaloids — oreintine, O-methylisothebaine, and orientidine, the structures of which have been established.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 81–83, January–February, 1984.     

Alkaloids ofAconitum orientale

Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 828–829, November–December, 1994.     

A new clerodane diterpene with antifeedant activity from Teucrium tomentosum

A new diterpene, viz. 3β‐acetoxy‐4α,18:15,16‐di­epoxy‐6β,12‐di­hydroxy­neocleroda‐13(16),14‐dien‐19,20‐olide, C₂₂H₂₈O₈, exhibiting antifeedant activity against Spodoptera litura was isolated from the aerial parts of Teucrium tomentosum and its structure is reported. One of the two fused rings has a distorted‐chair conformation and the other has a chair conformation. The mol­ecules in the crystal are stabilized via O—H...O and C—H...O hydrogen bonds.     

Alkaloids of Aconitum orientale

Institute of the Chemistry of Plant Substances, Uzbek Academy of Sciences, Tashkent. Pyatigorsk Pharmaceutical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 864–865, November–December, 1991.