吉林大学高分子学科:惟实励新 笃行致远

吉林大学高分子学科创建于1958年,是吉林大学化学学科的重要分支。在64年的学科发展中,一代代吉大高分子人惟实励新、砥砺奋进,建设了具有理工融合特色的高分子专业,培养了大批高分子科学领域的优秀人才。回顾了吉大高分子学科的发展历程,重点介绍了吉大高分子学科在课程建设、人才培养、科学研究等方面的成就进展。在吉大化学70周年华诞之际,谨以此文致敬那些为吉大高分子学科发展做出贡献的校友、同仁和朋友们。     

吉林大学分析化学学科:薪火相传 服务社会

2022年是吉林大学化学学科创建70周年,分析化学作为吉林大学化学学科的重要分支学科始建于1952年。回顾了吉林大学分析化学学科的历史沿革和发展成就。一代代吉大分析化学人始终秉承“献身、创新、求实、协作”的科学精神,为国家培养了一大批优秀人才。谨以此文,敬献给为吉林大学分析化学学科发展做出贡献的校友和朋友们。     

吉林大学无机化学学科:继往开来 砥砺前行

吉林大学无机化学学科创建于1952年,至今已有70年历史,几代吉大无机化学人踔厉奋发、笃行不怠,一直为建设世界一流学科而努力奋斗。回顾了吉大无机化学学科的历史沿革和奋斗历程,并着重介绍了吉大无机化学学科在教材建设、课程建设、科技创新和人才培养等4个方面的卓越成就。谨以此文,致敬那些为吉大无机化学学科发展做出贡献的前辈、同事和同学们。     

吉林大学物理化学一流课程的建设历程*

依托吉林大学化学学科发展,建设吉林大学物理化学一流课程,培养一流化学学科创新人才。主要简介吉林大学物理化学一流课程的建设,包括课程的发展经历;教学团队建设;课程特色和创新性;物理化学课程的教学改革;教材的建设;教学研究项目及发表教学文章;教学与科研相结合等。     

高等学校化学类外国教材研究成果交流会

受国家教委委托,于1990年9月6日—8日在吉林大学召开了高等学校化学类外国教材研究成果交流会。参加会议的有清华、复旦、南大、南开、吉大等13个单位,收到论文32篇。内容包括普通化学、无机、分析、有机、物理化学,还有环境化学、生物化学、有机地球化学、食品化学、高分子化学等专业学科;涉及美、英、苏、德、法、印度、挪威、日本等国化学教材。吉林大学外国教材中心作了题为“外国教材中心历史沿革、藏书建设与服务工作情况介绍”的大会发言。研究论文有对外国教材的介绍、评价,尤其侧重分析外国教材的先进性、科学性和继承性;有分析外国教材的编写特点;国内外教材的对比研究;介绍国外教材建设     

吉林大学应用化学学科:理工兼备 特色发展

吉林大学应用化学学科始建于1986年,依托吉林大学化学学科深厚理论基础与学术优势,经过几代应用化学学科人的不懈努力,逐渐形成了“理工兼备”的学科特色。在吉林大学化学学科70华诞之际,回顾了应用化学学科的发展历程,着重介绍了应用化学学科在本科教学与专业特色、科学研究与平台建设、人才培养与社会服务等3个方面取得的成绩,以及今后发展的设想。     

土壤胶体化学家虞宏正的学术思想与科学贡献

虞宏正是我国著名的胶体化学与物理化学家、教育家。他扎根西北,融汇世界思想,形成了颇具价值的学术思想,至今仍是当代科学研究的精髓与主导思想。他毕生致力于胶体化学、热力学研究,建立了新的分支学科,开创了土壤科学研究所,培育了几代化学科学家,为中国化学学科和农业科学的发展做出了重要的贡献。     

吉林大学化学学科物理化学课程的改革探索

以“基础学科拔尖学生培养试验计划”和人才培养基地的建设为背景,介绍了吉林大学在“拔尖计划”项目带动下,化学学院物理化学课程团队围绕教学理念、教学方法、考核方式方法、团队建设、教材建设及信息化建设等方面进行改革与建设中取得的经验与成果。以期为化学学科基础人才培养过程中基础课程体系的教学改革提供借鉴。     

优化物理化学学科资助布局，提升科学基金资助效能

本文总结了物理化学学科代码的设立和调整变化情况,结合近十年物理化学学科研究发展趋势,论述了自2018年物理化学学科代码优化调整为催化与表界面化学和化学理论与机制以来,优化学科布局对于促进学科前沿基础研究和提升科学基金资助效能方面起到了重要作用,提出了在优化学科布局方面的思考和建议,为后续学科发展战略提供参考。     

提高实验室安全管理水平 为学科人才培养保驾护航

化学是一门以实践为基础的学科,保障实验室安全是学科发展建设中的重要事项,是教学和科研正常有序进行的基本需求。以提升吉林大学化学学院实验室管理水平为目标,从制度体系、培训体系、保障体系、文化体系等方面在本科实验教学平台和科研平台开展的具体举措为例,探索出适合实际发展需求的实验室安全管理模式,为化学学科的建设与人才培养保驾护航。     

二氧化碳和丙烯直接合成甲基丙烯酸的NiPMo/TiO2催化剂的研究

用溶胶-凝胶法以磷钼酸(MPA)的镍盐溶液水解钛酸四丁酯制备了NiPMo/TiO2催化剂.使用ICP、 XRD、 TG-DTA、 IR、 TPD-MS和微反应技术研究了催化剂的化学组成、热稳定性、化学吸附性质和催化反应性能.杂多钼酸盐与TiO2通过O2-在TiO2表面发生了键合.在623 K下,杂多阴离子仍保持原有的Keggin结构.CO2在Lewis酸位Ni(Ⅱ)和Lewis碱位Ni-O-Mo的桥氧协同作用下生成CO2卧式吸附态Ni(Ⅱ)←O-(CO)←(O--Ni).丙烯有多种吸附态在催化剂上吸附.在563 K、 1 MPa和空速1500 h-1的反应条件下,丙烯的摩尔转化率为3.2%,产物MAA选择性为95%.     

CoFe2O4自形成磁性液体场致结构化对磁化的影响

The Langevin paramagnetic theory can’t describe the relation between magnetization of ferrofluids and applied magnetic field. The structuralization of ferrofluids, which is considered the main influence factor of the magnetization, is regarded. The part of magnetization works is deposited when the structure is forming. This action influences the magnetization of ferrofluids directly or indirectly. On the base of the “compressing” model, the Langevin function that usually describes the magnetization of ferrofluid is modified, and a well-fitted curve is obtained. An equation of the relation between the equivalent volume fraction after being “compressed” and the intensity of magnetic field is discovered, which approximately describes the process of magnetization. The relation between the approximate initial susceptibility and the volume fraction can be obtained from modified formula.     

Highly regioselective Buchwald–Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries

The highly regioselective Buchwald–Hartwig amination at C-2 of the cheap and readily accessible reagent, 2,4-dichloropyridine with a range of anilines and heterocyclic amines is described. This new methodology is robust and provides a facile access to 4-chloro-N-phenylpyridin-2-amines on 0.25 mol scale. These intermediates undergo a further Buchwald–Hartwig amination at higher temperature to enable rapid exploration of the chemical space at C-4 and to provide a library of 2,4-bisaminopyridines.     

Sulfur-directed metal-free and regiospecific methyl C(sp3)–H imidation of thioanisoles

Regiospecific and direct imidation of the methyl C(sp³)–H bond of thioanisoles is realized under mild and metal-free conditions with N-fluorobis(benzenesulfonyl)imide as an oxidant and nitrogen source. Proposed mechanism suggests that thionium ion intermediates and a Pummerer-type reaction are involved. The imidation has advantages such as high step-economy, excellent functionality tolerance, and regiospecificity, giving structurally diverse imidation products.     

Selective syntheses of 2H-1,3-oxazines and 1H-pyrrol-3(2H)-ones via temperature-dependent Rh(II)-carbenoid-mediated 2H-azirine-ring expansion

The Rh(II)-catalyzed reaction of 2-carbonyl-substituted 2H-azirines with ethyl 2-cyano-2-diazoacetate or 2-diazo-3,3,3-trifluoropropionate provides an easy access to 2H-1,3-oxazines and 1H-pyrrol-3(2H)-ones. These compounds can be selectively prepared from the same starting material using temperature as the only varied parameter. The 2-azabuta-1,3-diene intermediate, a common precursor for both heterocyclic products, isomerizes into 2H-1,3-oxazine under kinetic control, while 1H-pyrrol-3(2H)-one is the sole product of the reaction at elevated temperatures. According to DFT-calculations a one-atom oxazine ring contraction involving ring-opening to a 2-azabuta-1,3-diene intermediate, followed by a 1,5- and 1,2-prototropic shift leads to the consecutive formation of imidoylketene and azomethine ylide, which then further undergo cyclization to the pyrrole derivative.     

Copper catalyzed/mediated synthetic methodology for ebselen and related isoselenazolones

Scope of the copper catalyzed/mediated selenium-nitrogen coupling reaction has been studied for the synthesis of isoselenazolones. It is noticed that the 2-chloro, 2-bromo-, and 2-iodo-aryl amides substrates can be exploited in the selenium-nitrogen coupling reaction by employing 25-100 mol % of CuI/1,10-phenanthroline (L) and potassium carbonate as a base in DMF. Furthermore, electron rich 2-chloro-arylamides also underwent selenium-nitrogen coupling reaction to give biologically important selenium-nitrogen heterocycles. Also, copper-catalyzed selenium-nitrogen coupling reaction has been meticulously applied for the synthesis of diaryl diselenides having methoxy, amine, and amide functionality from respective aryl iodides in the presence of stoichiometric amount of succinimide as an external Se-N coupling partner.     

Knoevenagel condensation catalyzed by novel Nmm-based ionic liquids in water

A series of novel N-methyl morpholine (Nmm) based ionic liquids with 1,2-propanediol group were synthesized and used as catalysts for Knoevenagel condensation at room temperature in water. Under the effect of the catalyst, various aldehydes or aliphatic ketones could react with a wide range of activated methylene compounds well, including malononitrile, alkyl cyanoacetate, cyanoacetamide, β-diketone, barbituric acid, 2-arylacetonitrile and thiazolidinedione. Furthermore, most of the products could be separated just by filtrating and washing with water. Additionally, the catalyst is recyclable and applicable for the large-scale synthesis.     

Construction of polyheterocyclic spirotetrahydrothiophene derivatives via sulfa-Michael/aldol cascade reaction

A series of polyheterocyclic spirotetrahydrothiophene derivatives were obtained in moderate to excellent yields via a catalyst-free sulfa-Michael/aldol cascade reaction of chalcones 1 and commercially available 1,4-dithiane-2,5-diol 2 under mild conditions. We also present the first asymmetric sulfa-Michael/aldol cascade reaction of chalcones 1 and commercially available 1,4-dithiane-2,5-diol 2 with moderate to good enantioselectivities catalyzed by readily available chiral phase-transfer catalysts (PTCs).     

Suzuki-Miyaura reactions of the soluble guanylate cyclase inhibitor NS2028: a non-product specific route to C-8 substituted analogues

Both soluble guanylate cyclase (sGC) inhibitors ODQ 1 and NS2028 2 are synthesized via improved protocols. In the former case treating 3,4-dihydroquinoxalin-2(1H)-one oxime 8, which can be prepared in two steps from 1,2-benzenediamine, with 1,1′-carbonyldiimidazole (CDI) gives the dihydro-ODQ 10 that in the presence of KMnO₄ oxidises to give ODQ 1 in an overall yield of 46% starting from 1,2-benzenediamine. In the latter case, the synthesis affords NS2028 2 from 2-amino-4-bromophenol 3 in three steps with an overall yield of 85% and avoids the need for chromatography. Furthermore, Suzuki-Miyaura reaction conditions are described that enable the preparation of 8-aryl and 8-heteroaryl derivatives of NS2028 directly from NS2028 2. Finally, demethylation of the 8-(methoxyphenyl) substituted analogues afforded the 8-(hydroxyphenyl) derivatives 40-42. All new products are fully characterised.