弘扬地方文化 优化课堂教学——将闽都文化融入中学化学教学

分析地方文化融入中学化学的重要性与必要性,整理闽都文化中涉及的化学知识。以脱胎漆器、茉莉花茶、糖画为例,进行化学教学应用的设计,提出促进地方文化更好地融入中学化学教学的建议,旨在促进学生人文底蕴、家国情怀的培养,科学精神、辩证思维的形成。     

《梦溪笔谈》融入中学化学教学的探索

尝试将《梦溪笔谈》融入中学化学教学,将该著作中《巫咸河》《沈卢鱼肠》《石油》《胆矾炼铜》与胶体、合金、石油的分馏、置换反应等化学知识结合,以问题情境导入和试题编制等形式,帮助学生理解化学知识,培养综合素质,“润物细无声”地传承优秀传统文化。     

化学史融入中学化学课程“四线式”教学模式的构建

在借鉴已有科学史融入其他学科教学模式的基础上,针对目前化学史融入中学化学课程的实际教学现状,经过多次教学实践的检验,提出了一种将化学史有效融入中学化学教学实践的“历史线”“探究线”“知识线”和“应用线”的四线式教学模式,该模式可将化学核心素养的培养贯穿于整个教学之中。     

传统文化融入中学化学教学——“非遗印染技艺”的教学资源开发

从染料的利用历史、传统印染工艺、印染环保创新等3个维度挖掘了非遗印染技艺的教学资源，与萃取、自然资源开发利用、还原剂、硫及其化合物、酚醇性质、配合物、电解池等化学知识结合，以印染技艺为载体将传统文化、思政教育与化学教学有机融合，落实化学学科核心素养的发展，为传统文化融入中学化学教学提供借鉴。     

化学史融入初中化学教学现状的调查与对策研究

为了准确掌握内蒙古地区化学史融入初中化学实际教学的现状与不足。研究选取内蒙古地区10所初中的603名学生和38所初中的113名初中化学教师进行了问卷调查。结果表明内蒙古初三学生对化学史有较浓厚的兴趣,渴望通过化学史知识的学习激发学习化学的兴趣、理清知识脉络、提高创新探究能力、学会科学研究方法,而当前化学教学中存在化学史教学方法单一、化学史融入教学的程度较低、应试教育严重限制化学史教学的开展等诸多问题。针对存在的问题,研究提出化学史融入中学化学教学的"四线式"教学模式,以期改观内蒙古地区化学史融入初中化学实际教学的现状。     

利用知识竞赛实现中学化学STS知识的有效教学

从当前中学化学STS知识的教学现状出发,借鉴有效教学的理论,以化学知识竞赛为教学载体,对中学化学中STS知识的有效教学进行了研究,构建了化学STS知识的有效教学的框架,并对其进行了教学实践的研究,以期能为中学化学STS知识的教学提供一定的参考。     

研究期刊感悟高考启迪复习——源于《化学教育》的2006年高考试题评析与启示

《化学教育》开设的“生活中的化学”、“化学与社会”、“知识介绍”等栏目为中学化学教学提供了丰富鲜活的知识,开阔了读者视野,激活了中学化学基础知识,同时为高考命题提供了素材。笔者研究2006年高考化学试题,发现部分试题选材源于《化学教育》,这对引导中学化学老师研究《     

中德化学教学研讨会

1988.8.1.—5.中德中学化学教学研讨会在京举行。到会的联邦德国化学会派来的专家有其化学教育负责人Hofacker博士和设在Übervngen的国际化学教育网(INCE)的AssociatedCentre的Serafimov博士。他们分别向与会者介绍了联邦德国中学化学教育的历史、现状、体制、目标与方法等。与会者对其多轨教育体制、注重化学实际知识、生动的电化教育等反响热烈,很感兴趣。我会化学教育委员会也约请了七人就我国中学化学教育的任务、要求、发展、重点研究课题、计算机辅助教学、国际动态等方面作了报告。     

美国中学化学教材关于摩尔概念的处理及对我们的启示

摩尔是中学化学教学的重要概念,在整个中学化学计算中处于核心地位.由于摩尔概念本身较为抽象,加上涉及到物质结构、物理量、化学史等知识,因而它又是中学化学教学中的一个难点.     

中学化学史教育综述

重视科学史教育,把科学的思想观、典型事例、演变发展过程融入科学课程和科学教学之中,已成为当代科学教育发展的一大特点.从化学史教育功能的认识和化学史教育的形式、途径与方法2方面分析了国内中学化学史教育状况,对我国中学化学史教育进行了反思,从中得到了一些启示.     

二氧化碳和丙烯直接合成甲基丙烯酸的NiPMo/TiO2催化剂的研究

用溶胶-凝胶法以磷钼酸(MPA)的镍盐溶液水解钛酸四丁酯制备了NiPMo/TiO2催化剂.使用ICP、 XRD、 TG-DTA、 IR、 TPD-MS和微反应技术研究了催化剂的化学组成、热稳定性、化学吸附性质和催化反应性能.杂多钼酸盐与TiO2通过O2-在TiO2表面发生了键合.在623 K下,杂多阴离子仍保持原有的Keggin结构.CO2在Lewis酸位Ni(Ⅱ)和Lewis碱位Ni-O-Mo的桥氧协同作用下生成CO2卧式吸附态Ni(Ⅱ)←O-(CO)←(O--Ni).丙烯有多种吸附态在催化剂上吸附.在563 K、 1 MPa和空速1500 h-1的反应条件下,丙烯的摩尔转化率为3.2%,产物MAA选择性为95%.     

CoFe2O4自形成磁性液体场致结构化对磁化的影响

The Langevin paramagnetic theory can’t describe the relation between magnetization of ferrofluids and applied magnetic field. The structuralization of ferrofluids, which is considered the main influence factor of the magnetization, is regarded. The part of magnetization works is deposited when the structure is forming. This action influences the magnetization of ferrofluids directly or indirectly. On the base of the “compressing” model, the Langevin function that usually describes the magnetization of ferrofluid is modified, and a well-fitted curve is obtained. An equation of the relation between the equivalent volume fraction after being “compressed” and the intensity of magnetic field is discovered, which approximately describes the process of magnetization. The relation between the approximate initial susceptibility and the volume fraction can be obtained from modified formula.     

Highly regioselective Buchwald–Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries

The highly regioselective Buchwald–Hartwig amination at C-2 of the cheap and readily accessible reagent, 2,4-dichloropyridine with a range of anilines and heterocyclic amines is described. This new methodology is robust and provides a facile access to 4-chloro-N-phenylpyridin-2-amines on 0.25 mol scale. These intermediates undergo a further Buchwald–Hartwig amination at higher temperature to enable rapid exploration of the chemical space at C-4 and to provide a library of 2,4-bisaminopyridines.     

Sulfur-directed metal-free and regiospecific methyl C(sp3)–H imidation of thioanisoles

Regiospecific and direct imidation of the methyl C(sp³)–H bond of thioanisoles is realized under mild and metal-free conditions with N-fluorobis(benzenesulfonyl)imide as an oxidant and nitrogen source. Proposed mechanism suggests that thionium ion intermediates and a Pummerer-type reaction are involved. The imidation has advantages such as high step-economy, excellent functionality tolerance, and regiospecificity, giving structurally diverse imidation products.     

Selective syntheses of 2H-1,3-oxazines and 1H-pyrrol-3(2H)-ones via temperature-dependent Rh(II)-carbenoid-mediated 2H-azirine-ring expansion

The Rh(II)-catalyzed reaction of 2-carbonyl-substituted 2H-azirines with ethyl 2-cyano-2-diazoacetate or 2-diazo-3,3,3-trifluoropropionate provides an easy access to 2H-1,3-oxazines and 1H-pyrrol-3(2H)-ones. These compounds can be selectively prepared from the same starting material using temperature as the only varied parameter. The 2-azabuta-1,3-diene intermediate, a common precursor for both heterocyclic products, isomerizes into 2H-1,3-oxazine under kinetic control, while 1H-pyrrol-3(2H)-one is the sole product of the reaction at elevated temperatures. According to DFT-calculations a one-atom oxazine ring contraction involving ring-opening to a 2-azabuta-1,3-diene intermediate, followed by a 1,5- and 1,2-prototropic shift leads to the consecutive formation of imidoylketene and azomethine ylide, which then further undergo cyclization to the pyrrole derivative.     

Copper catalyzed/mediated synthetic methodology for ebselen and related isoselenazolones

Scope of the copper catalyzed/mediated selenium-nitrogen coupling reaction has been studied for the synthesis of isoselenazolones. It is noticed that the 2-chloro, 2-bromo-, and 2-iodo-aryl amides substrates can be exploited in the selenium-nitrogen coupling reaction by employing 25-100 mol % of CuI/1,10-phenanthroline (L) and potassium carbonate as a base in DMF. Furthermore, electron rich 2-chloro-arylamides also underwent selenium-nitrogen coupling reaction to give biologically important selenium-nitrogen heterocycles. Also, copper-catalyzed selenium-nitrogen coupling reaction has been meticulously applied for the synthesis of diaryl diselenides having methoxy, amine, and amide functionality from respective aryl iodides in the presence of stoichiometric amount of succinimide as an external Se-N coupling partner.     

Knoevenagel condensation catalyzed by novel Nmm-based ionic liquids in water

A series of novel N-methyl morpholine (Nmm) based ionic liquids with 1,2-propanediol group were synthesized and used as catalysts for Knoevenagel condensation at room temperature in water. Under the effect of the catalyst, various aldehydes or aliphatic ketones could react with a wide range of activated methylene compounds well, including malononitrile, alkyl cyanoacetate, cyanoacetamide, β-diketone, barbituric acid, 2-arylacetonitrile and thiazolidinedione. Furthermore, most of the products could be separated just by filtrating and washing with water. Additionally, the catalyst is recyclable and applicable for the large-scale synthesis.     

Construction of polyheterocyclic spirotetrahydrothiophene derivatives via sulfa-Michael/aldol cascade reaction

A series of polyheterocyclic spirotetrahydrothiophene derivatives were obtained in moderate to excellent yields via a catalyst-free sulfa-Michael/aldol cascade reaction of chalcones 1 and commercially available 1,4-dithiane-2,5-diol 2 under mild conditions. We also present the first asymmetric sulfa-Michael/aldol cascade reaction of chalcones 1 and commercially available 1,4-dithiane-2,5-diol 2 with moderate to good enantioselectivities catalyzed by readily available chiral phase-transfer catalysts (PTCs).     

Suzuki-Miyaura reactions of the soluble guanylate cyclase inhibitor NS2028: a non-product specific route to C-8 substituted analogues

Both soluble guanylate cyclase (sGC) inhibitors ODQ 1 and NS2028 2 are synthesized via improved protocols. In the former case treating 3,4-dihydroquinoxalin-2(1H)-one oxime 8, which can be prepared in two steps from 1,2-benzenediamine, with 1,1′-carbonyldiimidazole (CDI) gives the dihydro-ODQ 10 that in the presence of KMnO₄ oxidises to give ODQ 1 in an overall yield of 46% starting from 1,2-benzenediamine. In the latter case, the synthesis affords NS2028 2 from 2-amino-4-bromophenol 3 in three steps with an overall yield of 85% and avoids the need for chromatography. Furthermore, Suzuki-Miyaura reaction conditions are described that enable the preparation of 8-aryl and 8-heteroaryl derivatives of NS2028 directly from NS2028 2. Finally, demethylation of the 8-(methoxyphenyl) substituted analogues afforded the 8-(hydroxyphenyl) derivatives 40-42. All new products are fully characterised.