共查询到19条相似文献,搜索用时 93 毫秒
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《合成化学》2015,(9)
以1-金刚烷甲酸为原料,经酰化,取代和还原反应制得N,N-二甲基-1-金刚烷基甲胺(1);1与双子季铵盐(2)在无水乙醇中反应合成了一种新型的金刚烷基杂双子表面活性剂——1-(N,N-二甲基-1-金刚烷甲基溴化铵)-6-(N,N-二甲基-十二烷基溴化铵)-己烷(3),总收率30.9%,其结构经1H NMR和元素分析表征。采用表面张力法研究了3的表面活性。结果表明:3具有较强的聚集能力和界面吸附能力,其cmc,γcmc,p C20,Γmax,Amin分别为1.18 mmol·L-1,35.5 m N·m-1,0.48,2.63μmol·m-2和0.63 nm2。 相似文献
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本文报道查耳酮用H2O2在手性表面活性剂N,N-二甲基-N-十二烷基麻黄素澳化铵(1a)及N,N-二甲基-N-十六烷基麻黄素溴化铵(1b)形成的手性胶柬水溶液中的不对称环氧化反应,得到相应的手性α,β-环氧酮,对映体过量为5~8%. 相似文献
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分别采用N-十六烷基-N-(羟乙基)-N,N-二甲基溴化铵(CHDAB)和丁烷-1,4-二(N-十六烷基-N,N-二甲基溴化铵)(G16-4-16)2种阳离子表面活性剂作为金属表面修饰剂, 在石油醚/正丁醇/水混合体系中用KBH4 还原HAuCl4制备出亲油性纳米金. 其中, 双子表面活性剂G16-4-16显示出更好的包裹分散作用, 其包裹的纳米金粒径分布范围较窄, 平均粒径为5.2 nm. 将该纳米金颗粒分散在液态烷烃、 甲苯和长链烷基醇等溶剂中可制成稳定的油基纳米流体. 采用紫外-可见光谱法跟踪热稳定性随时间的变化, 结果表明, 该纳米流体显示了较好的热稳定性, 在130 ℃稳定时间达20 h. 采用点热源法测定了该纳米流体的导热系数, 结果表明, 50 ℃时添加质量分数1.5%的纳米金可以使其导热系数增大约17%. 相似文献
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V. D. Svlridov N. D. Chkanikov A. B. Shapiro N. V. Klimova B. M. Pyatin A. F. Kolomiets A. V. Fokin 《Russian Chemical Bulletin》1989,38(10):2161-2162
N-(1-Adamantyl)-4-(1-hydroxy-1-trifluoromethyl- 2,2,2- trifluoroethyl)aniline (III) and N-(1-adamantyl)-4-(1-hydroxy-1-methoxycarbony 1-2,2,2-trif luoroethyl) aniline (IV) were obtained by the reaction of N-(1-adamantyl)aniline with ketone (I) and ketoester (II). Analogous procedures gave N-(2-adamantyl)- 4- (1-hydroxy- 1-trifluoromethyl- 2, 2,2-trifluoroethyl)aniline (V) and N-(2-adamantyl)-4-(1-hydroxy-1-methoxycarbonyl-2,2,2-trifluoroethyl)aniline (VI). The action of hydrogen peroxide on (III) in the presence of sodium tungstenate gave N- (1- adamantyl)- 4- (1- hydroxy- 1- trifluoromethyl- 2,2,2- trifluoroethyl)aniline N-oxide (VII).Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 10, pp. 2348–2350, October, 1989. 相似文献
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Tomonari Y Murakami H Nakashima N 《Chemistry (Weinheim an der Bergstrasse, Germany)》2006,12(15):4027-4034
We describe the design of polycyclic aromatic compounds with high performance that dissolve single-walled carbon nanotubes (SWNTs). Synthetic amphiphiles trimethyl-(2-oxo-2-phenylethyl)-ammonium bromide (1) and trimethyl-(2-naphthalen-2-yl-2-oxo-ethyl)-ammonium bromide (2) carrying a phenyl or a naphtyl moiety were not able to dissolve/disperse SWNTs in water. By contrast, trimethyl-(2-oxo-2-phenanthren-9-yl-ethyl)-ammonium bromide (3) solubilized SWNTs, although the solubilization ability was lower than that of trimethyl-(2-oxo-2-pyrene-1-yl-ethyl)-ammonium bromide (4) (solubilization behavior observed by using 4 was described briefly in reference 4a). Transmission electron microscopy (TEM), as well as visible/near-IR, fluorescence, and near-IR photoluminescence spectroscopies were employed to reveal the solubilization properties of 4 in water, and to compare these results with those obtained by using sodium dodecyl sulfate (SDS) and hexadecyltrimethylammonium bromide (HTAB) as solubilizers. Compound 4 solubilized both the as-produced SWNTs (raw-SWNTs) and purified SWNTs under mild experimental conditions, and the solubilization ability was better than that of SDS and HTAB. Near-IR photoluminescence measurements revealed that the chiral indices of the SWNTs dissolved in an aqueous solution of 4 were quite different from those obtained by using micelles of SDS and HTAB; for a SWNTs/4 solution, the intensity of the (7,6), (9,5), and (12,1) indices were strong and the chirality distribution was narrower than those of the micellar solutions. This indicates that the aqueous solution of 4 has a tendency to dissolve semiconducting SWNTs with diameters in the range of 0.89-1.0 nm, which are larger than those SWNTs (0.76-0.97 nm) dissolved in the aqueous micelles of SDS and HTAB. 相似文献
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Sergey V. Krasnikov 《Tetrahedron letters》2004,45(4):711-714
An efficient synthesis of 4-(1-adamantyl)benzoic acid based on transition metal ion catalyzed oxidation of 4-(1-adamantyl)toluene has been developed. As a catalytic system, cobalt-manganese bromide with addition of manganese acetate was used. A series of amino acid derivatives of 4-(1-adamantyl)benzoic acid was then synthesized and characterized. These derivatives are novel intermediates potentially useful in the design of therapeutically active peptidomimetics with improved pharmacokinetic and pharmacodynamic parameters. 相似文献
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This paper describes enantiomer separation using four kinds of chiral stationary phases (CSPs) where quaternary ammonium surfactants containing L-valine diamide moieties into long alkyl chains were bound to silicagel supports by reversed phase liquid chromatography. Our aim was to examine hydrogen bonding association of the chiral moiety in hydrophobic phase brought about by aggregation of the micelle-forming surfactants on the surface. The following CSPs were thus derived from the vinyl-terminated chiral surfactants via hydrosilylation: CSP 1 from N-[3-(10-undecenoyl-L-valylamino)propyl]-N,N,N-trimethylammonium bromide, CSP 2 from N-[6-(10-undecenoyl-L-valylamino)hexyl]-N,N,N-trimethyl-ammonium bromide, CSP 3 from N-[3-(10-undecenoyl-L-valylamino)propyl]-N-octadecanyl-N,N-dimethyl-ammonium bromide and CSP 4 from N-[6-(10-undecenoyl-L-valylamino)hexyl]-N-octadecanyl-N,N-dimethylammonium bromide. The degree of hydrophobicity in the interfacial phase was observed by measuring pyrene fluorescence in aqueous media including an organic modifier. Retention of racemic N-acylleucine isopropyl esters was highest in CSP 4, followed by 3, 2, and 1. Largest alpha values toward enantiomer separation were observed for CSP 4 where the chiral moieties were kept through a hexamethylene unit apart from the polar head groups and to which another long alkyl chain was attached, as compared with those for CSP 4. In CSP 4, the chiral moiety to interact with enantiomeric solutes should be buried into the interfacial phase deeply in more extent than CSP 3. In a similar manner, CSP 2 has more effective for enantiomer separation than CSP 1. The interfacial phase of these CSPs was easily exposed to the bulk phase because of the affinity between the bulk phase and the polar head groups as well as their electrostatic repulsion. However, degree of the enantiomer separation can be controlled by the depth of the chiral moiety in the hydrophobic interfacial phase. 相似文献
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F. A. L. van der Horst M. H. Post J. J. M. Holthuis U. A. Th. Brinkman 《Chromatographia》1989,28(5-6):267-273
Summary Micellar phase-transfer catalysis (MPTC) offers the opportunity to derivatize carboxylic acids directly in an aqueous matrix without prior extraction of the acids into a suitable aprotic solvent. The currently developed MPTC system consists of a non-ionic surfactant, Arkopal N-130, an ion-pair agent, tetrakis-(decyl)-ammonium bromide, and a novel fluorescence reagent, 9-bromomethylacridine. The MPTC system can be applied to the derivatization of many types of carboxylic acids. The reaction rate is affected by the lipophilicity of the acid and by the presence of other functional groups. For lipophilic carboxylic acids the reaction is complete within 5 min at 60°C and pH 7.0. 相似文献
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McCullough DH Grygorash R Regen SL 《Langmuir : the ACS journal of surfaces and colloids》2007,23(19):9606-9610
Langmuir-Blodgett deposition of a single monolayer of 1,2,4,5-tetrakis[(N-(perfluoroundecanoamidoethyl)-N,N-dimethylammonium)methyl]benzene tetrabromide (1) onto a thin film made from alternating layers of poly(diallydimethylammonium chloride) (PDADMA) and poly(4-styrenesulfonate) (PSS) ions affords a uniform fluorinated surface of low energy. An analogous surface that has been constructed by self-assembly shows the same critical surface tension of 16.5 dyn/cm. A comparison of Zisman plots for these two modified films, in combination with analysis by X-ray photoelectron spectroscopy, indicates that Langmuir-Blodgett deposition produces a higher quality and more densely packed fluorocarbon surface that is very hydrophobic. In sharp contrast, the use of a single-chain analog (i.e., N-(perfluoroundecanoamidoethyl)-N,N,N-trimethylammonium bromide) (2)) affords relatively high energy surfaces by Langmuir-Blodgett deposition and by self-assembly. 相似文献
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Korotkikh NI Rayenko GF Shvaika OP Pekhtereva TM Cowley AH Jones JN Macdonald CL 《The Journal of organic chemistry》2003,68(14):5762-5765
Two new, more convenient methods for the synthesis of 1,2,4-triazol-5-ylidenes are described. Four new 1,2,4-triazol-5-ylidenes have been prepared using these methods: 1-(1-adamantyl)-3,4-diphenyl-1,2,4-triazol-5-ylidene (2a), 1-(1-adamantyl)-3-phenyl-4-(p-bromophenyl)-1,2,4-triazol-5-ylidene (2b), 1-(1-adamantyl)-3-phenyl-4-(alpha-naphthyl)-1,2,4-triazol-5-ylidene (2c), and 1-(1-adamantyl)-3,4-di(p-bromophenyl)-1,2,4-triazol-5-ylidene (2d). The X-ray crystal structures of 2d and the precursor salt 1-(1-adamantyl)-3,4-di(p-bromophenyl)-1,2,4-triazolium bromide (1e) are described. Compound 2a reacts with CH(3)CN via C-H insertion to form 1-(1-adamantyl)-3,4-diphenyl-5-cyanomethyl-5H-1,2,4-triazoline (3), and 2a and 2d react with elemental sulfur and elemental selenium, respectively, to form the corresponding thione (4) and selenone (5). 相似文献
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Milo? Luká? Ivan Lacko Marián Bukovsky Zuzana Kyselová Janka Karlovská Branislav Horváth Ferdinand Devínsky 《Central European Journal of Chemistry》2010,8(1):194-201
We synthesized nine quaternary ammonium compounds (QUATs) starting from phenylalanine, N-alkyl-N,N-dimethyl-(1-hydroxy-3-phenylpropyl)-2-ammonium bromides, which were prepared as optically pure substances. Five compounds
were prepared as S-enantiomers and four compounds as R-enantiomers. These compounds were evaluated by their activities against bacteria and fungi. Three microbial strains were
used in the study: the gram-negative bacteria Escherichia coli, the gram-positive bacteria Staphylococcus aureus and the fungi Candida albicans. The activities were expressed as minimum bactericidal or fungicidal concentrations (MBC). The most active compounds were
(2S)-N-tetradecyl-N,N-dimethyl-(1-hydroxy-3-phenylpropyl)-2-ammonium bromide and (2R)-N-tetradecyl-N,N-dimethyl-(1-hydroxy-3-phenylpropyl)-2-ammonium bromide, with MBC values exceeding those of commercial benzalkoniumbromide
(BAB) used as standard. The relationships between structure and biological activity of the tested QUATs were quantified by
the bilinear model (QSAR) and are discussed. 相似文献