This cover picture describes a novel palladium-catalyzed three-component tandem cyclization reaction between two molecular haloalkynes and one molecular N-alkylaniline for the efficient assembly of 3-halopyrroles. This protocol involves the sequential conversions of two carbon-carbon triple bonds and one carbon-halogen bond in two molecular haloalkynes and features convenient operation, high chemo- and regioselectivites, and good functional group tolerance. In addition, different derivatizations of the newly formed bromopyrroles afford diverse functionalized pyrrole derivatives, demonstrating the practicability of this method. More details are discussed in the article by Wu et al. on page 181—187.
The cover picture shows a facile synthetic methodology towards S-fused multi-membered polycyclic heterocycles containing five-membered thiophene, six-membered thiopyran, and seven-membered thiepine. A construction strategy for thermally stable thiepine derivatives is thus established. More details are discussed in the article by Zhou et al. on page 13—20.
The cover picture shows the molecular modeling software package SPONGE (Simulation Package tOward Next GEneration molecular modeling). SPONGE is designed to be efficient and highly modulated. Especially, advanced machine learning algorithms can be easily merged into MD simulations by using SPONGE. All these features increase the power of SPONGE for modeling and simulation of complex chemical and biological systems. More details are given in the article by Gao et al. on page 160–168.
In this paper, we design a new interrupted AST‐type zeolitic imidazolate framework with cub and interrupted ast cages, which exhibits permanent porosity, high hydrophobicity and strong solid‐state photoluminescent properties. More details are discussed in the article by Wang & Zhang et al. on page 449–452.
