Preparation of N-carbomethoxyaminopyrroles

Azoalkenes $\text{1}$ react with enamines and β-dicarbonyl compounds to give $\text{N}$-carbomethoxyaminopyrroles rather than $\text{N}$-carbomethoxy-1,2-dihydropyridazines.     

Oxidation of N-hydroxyazetidines: A novel synthesis of N-acetoxy β-Lactams and four-membered cyclic nitrones

The N-hydroxyazetidines $\text{2}$ and $\text{3}$ are prepared startinfrom 2,3-dihydroazete 1-oxides ($\text{1a}$ and $\text{1b}$0 by reduction with sodium borohydride and by reaction with a nucleophile, respectively. The N-thydroxyazetidines $\text{2}$ and $\text{3}$ can be oxidized with mercury (II) oxide to the corresponding nitrones $\text{1}$; oxidation of the N-hydroxyazetidine $\text{2a}$ (unsubstituted at C-4) with $\text{two}$ equivalent of lead tetraacetate tyields the N-tacetoxy β-lactam $\text{4}$.     

N-methyl-N-anilinomethyl diphenylphosphine oxide: a versatile reagent for the synthesis of enamines

Cyclic as well as acyclic ketones, both saturated and α,β-unsaturated, can be converted into their homologous enamines by Horner-Wittig reaction with $\text{N}$-methyl-$\text{N}$-anilinomethyl diphenylphosphine oxide ($\text{3}$).     

O- versus N-methanesulphonylation and N-(methanesulphonyl)-methanesulphonylation with methanesulphonyl chloride

Depending upon the experimental conditions, t-butyl (1$\text{SR}$,5$\text{SR}$,7$\text{RS}$,8$\text{RS}$)-1-ethoxycarbonyl-8-hydroxy-2-oxa-6-azabicyclo[3.2.0]octane-7-carboxylate (2a) reacts with methanesulphonyl chloride to give predominantly the $\text{O}$-methanesulphonyl derivative (2b), the $\text{N}$-methanesulphonyl derivative (3a), or the $\text{N}$-(methanesulphonyl)methane-sulphonyl derivative (6a).     

Strtcture-colour relationships of some new n-aryipyridinuim hemicyanine dyes

$\text{N}$-aryl derivatives of 4-$\text{p-dimethylamino}$pyridine are novel examples of donor-acceptor dyes. $\text{Para}$-substituents in the $\text{N}$-aryl group influence the spectra, such that the more electron-withdrawing lead to more bathochromic shifts. However, a 2-nitro substituent in the $\text{N}$-aryl ring has surprisingly little influence on the absorption maximum. PPP-MO-CI calculations, and correlation and conformational analyses are applied to the study.     

Synthesis and characterization of 4-dimethylamino-N-triphenylmethylpyridinium chloride,a postulated intermediate in the tritylation of alcohols

4-Dimethylamino-$\text{N}$-triphenylmethylpyridinium chloride ($\text{1}$) reacts with primary but not secondary alcohols to produce trityl ethers in good yield; in addition, amines may be selectively $\text{N}$- tritylated witth $\text{1}$ in the presence of alcohols.     

A direct transformation of bicyclic keto esters to N-formimidoyl thienamycin

A convenient direct transformation of $\text{p}$-nitrobenzyl 6-(1′-hydroxyethyl)-1-azabicyclo-(3.2.0)heptane-3,7-dione-2-carboxylate to $\text{N}$-formimidoyl thienamycin utilizing the silylated derivative of $\text{N}$-formimidoyl cysteamine is described.     

Thermolysis of n-(o-azidobenzoyl)-iminopyridinium ylide: a new route to 3h-indazol-3-one

3$\text{H}$-Indazol-3-one has been generated by thermolysis of $\text{N}$($\text{o}$-azidobenzoyl)iminopyridinium ylide and trapped as its Diels-Alder cycloadducts with several dienes.     

A diels-alder adduct of n-methylflindersine and a quinolone quinone methide

A quinolone quinone methide ($\text{5}$; R=Me), prepared from 1,3-dimethyl-4- hydroxy-2-quinolone ($\text{7}$) and DDQ, reacted readily with $\text{N}$-methylflindersine ($\text{3}$) to give a single cyclo-addition product ($\text{4}$).     

Evidence for N2N3N45 super coster kronig processes in metallic Nb,Mo, Ru and Rh

The 4p photoelectron spectra of metallic Nb, Mo, Ru and Rh have been recorded. By use of a deconvolution procedure it is shown that the 4p_{$\text{1}\text{2}$} spin-orbit component has a linewidth which significantly exceeds that of the 4p_{$\text{3}\text{2}$} component. This suggests that N₂N₃N₄₅ super Coster Kronig processes give a considerable contribution to the decay rata of the 4p_{$\text{1}\text{2}$} hole state.     

Comparative reactions between aziridines and F2, COF2, CF3OF

In CFCl₃, aziridines $\text{I}$ react with F₂(6 %/N₂,  20°C), COF₂ (20 %/N₂,  40°C) and CF₃OF [1] (20 %/N₂,  40°C).Substitution products are obtained : l-(aziridine)carbonyl fluorides $\text{II}$ and l-Fluoroaziridines $\text{III}$

In (Et)₂O, aziridines $\text{I}$ react with COF₂ (20 %/N₂, 10°C) and we have the carbonyl fluorides $\text{IV}$.

Products IV can be thermally decomposed into β fluoro isocyanates.In CFCl₃, N substituted aziridines $\text{V}$ react with F₂(6%/N₂, 20°C) and with CF₃OF [2] (20%/N₂, 40°C). No reaction is observed with COF₂in our conditions (5% to 25%/N₂, 80°C to + 40°C).Addition products are obtained : N Fluoro amines β fluorinated $\text{VI}$, N Fluoro and NN difluoro amines β trifluoro methoxylated $\text{VII}$ and $\text{VIII}$.

with R = SO₂Ø, COØNO₂, Cl.     

Reaction between N-acyl-2,3-dihydrobenzo-1,4-thiazine and N-acylphenothiazine with organometallic reagents

the title $\text{N}$-acyl-derivatives react with $\text{n}$-BuLi and Grignard reagents leading to products, which, formally, can be considered as derived from a Claisen-type condensation reaction.     

Reaction of benzilmonohydrazone with S4N4, A correction

Reaction of benzilmonohydrazone(1) with S₄N₄ gives the azine (6) and not the 2-$\text{H}$-imidazole (2); this invalidates the claim that (2) is not the intermediate in the formation of $\text{N}$-benzoyltriphenylimidazole from benzil and ammonia. S₄N₄ converts diphenylketene into thiobenzophenone.     

Base-induced intramolecular cyclisation of N-(o-azidobenzoyl)-arylamines. A new synthesis of 2-aryl-1,2-dihydro-3H-indazolin-3-ones

In strong base, e.g., sodium hydride in dimethylformamide, $\text{N}$-($\text{o}$-azidobenzoyl)arylamines cyclise in high yield to 2-aryl-1,2-dihydro-3$\text{H}$-indazolin-3-ones.     

Photochemically induced reaction of 1, N4-dimethylcytosinewith isopropanol

Photoexcited 1, $\text{N}$⁴-dimethylcytosine (I) adds isopropanol to form 5,6-dihydro-1, $\text{N}$⁴-dimethyl-6-(2-hydroxy-2-propyl)cytosine (II) as the major product; a small amount of 5,6-dihydro-1-methyluracil (III) is formed as well.     

Peracid-mediated n-oxidation and rearrangement of dimethylphosphoramides: plausible model for oxidative bioactivation of the carcinogen hexamethylphosphoramide (HMPA)

Dimethylphosphoramides react with $\text{m}$-chloroperoxybenzoic acid (MCPBA) in anhydrous acetone to yield the previously unknown $\text{P}$-dimdethylamino-oxyphosphonous derivatives $\text{via}$$\text{N}$-oxidation and rearrangement. Further MCPBA oxidation yields formaldehyde and nitrosomethane, isolated as its $\text{trans}$-dimer. These reactions provide a possible biomimetic model for the metabolic activation of hexamethylphosphoramide as a mutagen and carcinogen.     

Microwave-optical double resonance in molecular ions. Co+

Microwave—optical double resonance signals have been detected in a mass-selected ion-beam spectrometer for ¹²C¹⁶O⁺. With the optical excitation of fluorescence from the R₁ ($\text{1}\text{2}$) line of the (0,0) band of the A²Π_{$\text{3}\text{2}$} ← X²∑ transition of 20350.6 cm^?1, the microwave resonances occurred at 118101.8 ± 0.2 MHz and at 117694 ± 2 MHz corresponding to the N= 1, J = $\text{3}\text{2}$ ← N = 0, J = $\text{1}\text{2}$ and the N = 1, J = $\text{1}\text{2}$ ← N = 0, J = $\text{1}\text{2}$ transitions.     

Fluorescence quantum yields and cascade-free lifetimes of state selected CO+2, COS+, CS+2 and N2O+ determined by photoelectron—photon coincidence spectroscopy

The details and principles of an apparatus built for measurements of fluorescence quantum yields and cascade-free lifetimes of open-shell cations are reported. These rely on the detection of coincidences between energy selected photoelectrons and undispersed photons. The results of such measurements for CO⁺₂, COS⁺, CS⁺₂ and N₂O⁺ in selected vibrational levels of their excited states are presented. Non-unity fluorescence quantum yields are found for some vibronic levels of CO⁺₂($\text{B}$), COS⁺ ($\text{A}$), N₂OP⁺($\text{A}$) and a non-exponential decay is observed for CS⁺₂($\text{A}$). The data yield the following values for the radiative lifetimes: CO⁺₂($\text{A}$) 124 ± 6 ns, CO⁺₂($\text{B}$) 140 ± 7 ns, COS⁺($\text{A}$) 550 ± 50 ns and N₂O⁺($\text{A}$) 240 ± 12 ns.     

Oxygenation of 2,6-di-t-butylphenols with superoxo Co(III) complexes

Superoxo Co(III) complexes, [Co(CN)₅O₂][X]₃ where X = Et₃N⁺ and (Ph₃P)₂N⁺, mediate the dioxygen incorporation into 2,6-di-$\text{t}$-butylphenols ($\text{1}$) with the same regioselectivity as that in the base-catalyzed oxygenation of $\text{1}$. The superoxo species acts as a base but is not incorporated into the substrate.     

6-alkyl- and 5,6-dialkyl-2-methoxy-4(3H)-pyrimidinones in the transformations of pyrimidines. Regiospecific 1-N-acylation of pyrimidines.

Transformation of 6- and 5,6-dialkyl-2-methoxy-4(3H)-pyrimidinones (1a and 1b) into 1-$\text{N}$-acylated-pyrimidine derivatives 3($\text{a}$-$\text{f}$) under Friedel-Craft like conditions is presented. In different acylation conditions 4-O-acylated-pyrimidines (5a and 5b) are also obtained. Compounds (3c) and (3f) can be directly converted into 1-$\text{N}$-acyl-protected-isouridine analogues (8a and 8b).