共查询到20条相似文献,搜索用时 31 毫秒
1.
V. R. Akhmetova N. N. Murzakova G. R. Khabibullina N. F. Galimzyanova 《Russian Journal of Applied Chemistry》2011,84(2):225-229
Possibility of obtaining water-soluble N- and N,N′-coordinated adducts by reacting 3,7-dithia-1,5-diazabicyclo[3.3.0]octane with methyl iodide and Brønsted (HCl, HBr) and Lewis (AlCl3) acids was examined. The fungicidal activity of 3,7-dithia-1,5-diazabicyclo[3.3.0]octane and its water-soluble adducts with hydrobromide and methyl iodide against a number of microscopic fungi affecting cultivated plants and various materials was studied. 相似文献
2.
L. N. Zharkikh G. F. Muzychenko V. G. Kul'nevich V. E. Zavodnik K. S. Pushkareva G. V. Golovko A. V. Ignatenko 《Chemistry of Heterocyclic Compounds》1992,28(7):738-741
The reduction of 2-oxa-6-oxo-3-phenyl-4-(R-phenyl)-7-(4-nitrophenyl)3,7-diazabicyclo[3.3.0]octanes with hydrazine hydrate in the presence of Raney nickel gave the corresponding amino alcohols. X-ray diffraction analysis established the stereochemistry of the molecule in the crystal of 1-(4-anilino)-3-[anilino(phenyl)methyl]-4-hydroxypyrrolidone-2.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 890–894, July, 1992. 相似文献
3.
V. R. Akhmetova N. N. Murzakova G. R. Khabibullina T. V. Tyumkina Z. A. Starikova I. S. Bushmarinov L. F. Korzhova 《Russian Chemical Bulletin》2012,61(1):141-147
Heterocyclization of hydrazine with aldehydes R-CHO (R = Me, Et, Prn, Bun, n-C5H11, Ph, 4-MeOC6H4, 3-Py) and H2S leads to stereoisomeric 2,4,6,8-tetrasubstituted 3,7-dithia-1,5-diazabicyclo[3.3.0]octanes, which were separated by column chromatography. The trans-transoid-trans-configuration of tetramethyl(-ethyl,-propyl)-3,7-dithia-1,5-diazabicyclo-[3.3.0]octanes was inferred from the X-ray diffraction and 1H and 13C NMR spectroscopic data. 相似文献
4.
D. R. Latypova N. Z. Baibulatova R. A. Khisamutdinov Yu. I. Murinov V. A. Dokichev 《Russian Journal of Inorganic Chemistry》2011,56(6):981-985
Complexation of copper(II) chloride, copper(II) triflate, and palladium(II) chloride with optically active L,L-3,7-bis[2-(4-hydroxyphenyl)-1-(methoxycarbonyl)ethyl]-1,5-di(ethoxycarbonyl)-3,7-diazabicyclo[3.3.1]nonan-9-one was studied. 相似文献
5.
G. A. Gazieva K. A. Lysenko A. N. Kravchenko O. V. Lebedev 《Russian Journal of Organic Chemistry》2007,43(11):1715-1718
Condensation of N,N′-dimethylsulfamide with glyoxal gave 2,4,6,8-tetramethyl-3,7-dithia-2,4,6,8-tetraazabicyclo[3.3.0]octane 3,3,7,7-tetraoxide, a sulfur-containing analog of 2,4,6,8-tetramethyl-2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-dione (Mebicar). The product structure was studied by X-ray analysis. 相似文献
6.
《Tetrahedron》2019,75(33):4444-4450
Novel 3,7-bis(dialkylaminoacetyl)-1,5-dimethyl-3,7-diazabicyclo[3.3.1]nonanes were synthesized, which can undergo conformational reorganization under the change of solvent polarity, protonation (the change of pH) or complexation with LaCl3. These compounds are capable of being embedded into the liposomal membranes and can serve as molecular switches for the development of stimulus-sensitive liposomal containers. 相似文献
7.
I. V. Grishina D. V. Makeev V. B. Rybakov V. L. Lapteva V. A. Palyulin N. S. Zefirov 《Doklady Chemistry》2017,477(1):239-243
3,7-Ditosyl-1,5-diphenyl-3,7-diazabicyclo[3.3.1]nonane has been found to adopt a chair–chair conformation in the crystalline state in contrast to 3,7-ditosyl-1,5-diphenyl-3,7-diazabicyclo[3.3.1]nonan-9-one, which had been previously found to exist in a chair-boat conformation. 相似文献
8.
E. A. Chigorina K. A. Frolov V. V. Dotsenko A. S. Goloveshkin I. S. Bushmarinov S. G. Krivokolysko 《Russian Chemical Bulletin》2016,65(9):2260-2269
Aminomethylation of triethylammonium 4-aryl-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olates and their sulfur and selenium analogs, as well as the structure of formed products, were studied in details. The reaction is of general character and leads to the formation of 7-substituted 9-aryl-2,4-dioxo-, 9-aryl-4-oxo-2-thioxo-, 9-aryl-4-oxo-2-selenoxo-3,7-diazabicyclo[3.3.1]nonane derivatives or their salts. The structures of ethyl 9-(2-chlorophenyl)-5-cyano-7-(4-methylphenyl)-2-oxo-4-thioxo-3,7-diazabicyclo[3.3.1]nonane-1-carboxylate (as a complex with N-methylmorpholine) and triethylammonium salt of 7-benzyl-4-oxo-2-selenoxo-9-(2-thienyl)-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitrile were studied by X-ray crystallography. 相似文献
9.
1,5-Hexadiene reacts with trifluoromethanesulfonamide in the oxidative system (t-BuOCl+NaI) to give trans-2,5-bis(iodomethyl)-1-(trifluoromethylsulfonyl)pyrrolidine 5 and 3,8-bis(trifluoromethylsulfonyl)-3,8-diazabicyclo[3.2.1]octane 6. With arenesulfonamides ArSO2NH2 (Ar=Ph, Tol), the reaction stops at the formation of the trans and cis isomers of 2,5-bis(iodomethyl)-1-(arenesulfonyl)pyrrolidine 7 and 8 (1:1). The cis isomers of 7 and 8 do not undergo cyclization to the corresponding 3,8-disubstituted 3,8-diazabicyclo[3.2.1]octanes. The reaction with triflamide represents the first example of one-pot two-step route to 3,8-diazabicyclo[3.2.1]octane system. 相似文献
10.
A. I. Kuznetsov K. I. Romanova E. B. Basargin A. S. Moskovskii B. V. Unkovskii 《Chemistry of Heterocyclic Compounds》1990,26(4):461-465
Heating 1,5-dinitro-3,7-di(tert-butyl)-3,7-diazabicyclo[3.3.1]-nonane with concentrated hydrobromic acid gives 1,5-dinitro-3,7-diazabicyclo[3.3.1]nonane. Cyclization of the latter with various aldehydes and ketones gave a series of 2,2-disubstituted 5,7-dinitro-1,3-diazaadamantanes. The behavior of the synthesized compounds under electron impact has been studied.For Communication 8 see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 538–542, April, 1990. 相似文献
11.
Ayats C Camps P Duque MD Font-Bardia M Muñoz MR Solans X Vázquez S 《The Journal of organic chemistry》2003,68(22):8715-8718
Two alternative syntheses of the new D2d symmetric tetramethyl tricyclo[3.3.0.0(3,7)]octane-1,3,5,7-tetracarboxylate from the known dimethyl 3,7-dioxo-cis-bicyclo[3.3.0]octane-1,5-dicarboxylate and 1,5-(2,2'-biphenylene)-cis-bicyclo[3.3.0]octane-3,7-dione are described. 相似文献
12.
Anastasiya N. Khrustaleva Konstantin A. Frolov Victor V. Dotsenko Nicolai A. Aksenov Inna V. Aksenova Sergey G. Krivokolysko 《Tetrahedron letters》2017,58(50):4663-4666
The aminomethylation of 4,4-dialkyl-2,6-dioxopiperidine-3,5-dicarbonitriles (Guareschi imides) was studied for the first time. When the Guareschi imides were treated with primary aliphatic amines and an excess of formaldehyde, 2,4-dioxo-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitriles were obtained in varying yields (15–67%). The structure of 9,9-dimethyl-7-(2-methylpropyl)-2,4-dioxo-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitrile was studied by X-ray diffraction analysis. 相似文献
13.
Syroeshkina Yu. S. Petukhova V. Yu. Kachala V. V. Nelyubina Yu. V. Makhova N. N. 《Russian Chemical Bulletin》2010,59(7):1433-1441
A reaction of aryl ketenes with 1-arylmethylidenepyrazolidin-1-azomethine imines, generated by the diaziridine ring opening
in 6-aryl-1,5-diazabicyclo[3.1.0]hexanes catalyzed with Et2O·BF3, leads to 1,2-bis(phenylacetyl)pyrazolidine, 2-arylacetyl-1-arylidenepyrazolidin-1-ium
chlorides, or a representative of 1,5-diazabicyclo[3.3.0]octan-2-ones, viz., 4-(4-eth-oxyphenyl)-3,3-diphenyl-1,5-diazabicyclo[3.3.0]octan-2-one, depending on the reaction conditions and the structure
of the starting compounds. A mechanism suggested earlier for the transformation of 1,5-diazabicyclo[3.1.0]hexanes in the reaction
with ketenes was confirmed. 相似文献
14.
Ts. E. Agadzhanyan G. L. Arutyunyan R. A. Movsesyan 《Chemistry of Heterocyclic Compounds》1998,34(8):979-982
The following heterocyclization reactions have been carried out: heterocyclization of 3,7-diacryloyl-3,7-diazabicyclo[3.3.1]nonane by benzylamine, heterocyclization of 3,7-diacryloyl-, 3,7-bis(-bromopropionyl)-, and 3,7-bis(-chloroethyl)-3,7-diazabicyclo[3.3.1]nonanes by hydrogen sulfide, and heterocyclization of 3,7-bis(bromoacetyl)- and 3,7-diacryloyl-1,3,7-triazabicyclo[3.3.1]nonanes by benzylamine and hydrogen sulfide. New compounds were obtained, based on previously unknown thiadiaza-, triaza-, and tetraazatricyclic systems.For Communication 25, see [1].A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia, Erevan 375014. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1133–1136, August, 1998. 相似文献
15.
A. V. Stepakov I. A. Galkin A. G. Larina A. P. Molchanov R. R. Kostikov 《Russian Journal of Organic Chemistry》2009,45(12):1776-1782
Ethyl 7-aryl-6,8-dioxo-2-oxa-3,7-diazabicyclo[3.3.0]oct-3-ene-4-carboxylates and ethyl 7-aryl-6,8-dioxo-1-oxa-2,7-diazaspiro[4.4]non-2-ene-3-carboxylates
were selectively reduced with sodium tetrahydridoborate at the carbonyl group in the β-position with respect to the oxygen
atom in the isoxazole ring. 相似文献
16.
Ayats C Camps P Fernández JA Vázquez S 《Chemistry (Weinheim an der Bergstrasse, Germany)》2007,13(5):1522-1532
Compounds isolated from the reaction of (+/-)-1,3-diiodotricyclo[3.3.0.0(3,7)]octane with molten sodium or tBuLi suggest the intermediate formation of (+/-)-1,3-dehydrotricyclo[3.3.0.0(3,7)]octane. Worthy of note is the formation of stereoisomeric bi(5-methylenebicyclo[2.2.1]hept-2-ylidene) derivatives, probably by coupling of two units of (+/-)-1,3-dehydrotricyclo[3.3.0.0(3,7)]octane of the same or different absolute configuration followed by fragmentation, processes that have been studied by theoretical calculations. 相似文献
17.
1-Carbethoxy-2,4,6,8-tetraaryl-3,7-diazabicyclo[3.3.1] nonan-9-ones (1, 2) were synthesized and their 1H and 13C NMR data are reported. Chemical shifts and spectral assignments for 2,4,6,8-tetrakis(4-chlorophenyl)-3,7-diazabicyclo[3.3.1]nonan-9-one (3), 2,4,6,8-tetraphenyl-3-thia-7-azabicyclo[3.3.1]nonan-9-one (4) and 2,4,6,8-tetraaryl-3,7-diazabicyclo[3.3.1]nonanes (5-7) are also included. 相似文献
18.
Kravchenko A. N. Maksareva E. Yu. Belyakov P. A. Sigachev A. S. Chegaev K. Yu. Lyssenko K. A. Lebedev O. V. Makhova N. N. 《Russian Chemical Bulletin》2003,52(1):192-197
New (1R*,5S*)-2-R-2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-diones containing the terminal carboxy or hydroxy group in the substituent R were synthesized by cyclocondensation of 4,5-dihydroxyimidazolidin-2-one with 1-R-ureas. Single-crystal X-ray diffraction analysis showed that 2-carboxyethyl-2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-dione crystallizes as a racemate. 相似文献
19.
A. N. Anfimov S. Yu. Erdyakov M. E. Gurskii Yu. N. Bubnov 《Russian Chemical Bulletin》2011,60(11):2336-2342
A general methodology for the stereoselective synthesis of compounds of the 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane series was developed. The strategy includes allylboration of aromatic aldehydes with 1,6-bis(dialkylboryl)-2,4-hexadiene, ozonolysis of the thus obtained 1,4-diaryl-2,3-divinyl-1,4-diols, and subsequent intramolecular cyclization. This methodology was used for obtaining the naturally occurring lignans of the furofuran series, viz., diaeudesmin, diayangambin, epiasarinin, epieudesmin, epiyangambin, and asarinin. 相似文献
20.
By the reaction of 1,5-dimethyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane with isatin and a number of its derivatives, spiro(1,3-diazaadamantane-2,3′-oxindoles)
have been synthesized. In the case of 5-bromoisatin, either 3-(3-hydroxyoxindolyl)-3,7-diazabicyclo[3.3.1]nonane or the corresponding
spirane is obtained, depending on the temperature. The interaction of these products with acetic anhydride has been studied.
For communication 24, see [1].
A. L. Mndzhoyan Institute of Fine Organic Chemistry, Academy of Sciences of the Republic of Armenia, Erevan 375014. Translated
from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1490–1493, November, 1997. 相似文献