首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 531 毫秒
1.
The title compound, C25H31NO2·H2O, has the outer two six‐membered rings in chair conformations, while the central ring is in an 8β,9α‐half‐chair conformation. The five‐membered ring adopts a 13,14‐half‐chair conformation. The pyridyl­methyl­ene moiety has an E configuration with respect to the carbonyl group at position 17. The structure is stabilized by intermolecular O—H?N and O—H?O hydrogen bonds.  相似文献   

2.
The title compound, C36H49NO5·H2O, has the outer two six‐membered rings of the steroid nucleus in chair conformations. The central ring B of the steroid nucleus is in an 8β,9α‐half‐chair conformation, while ring D of the steroid adopts a slightly distorted 13β,14α‐half‐chair conformation. The piperidine ring is in a chair conformation. The methoxy­benzyl­idene moiety has an E configuration with respect to the carbonyl group at position 17. Intermolecular O—H?O and O—H?N hydrogen bonds link the steroid and water mol­ecules into chains which run parallel to the b axis.  相似文献   

3.
In the title compound, C31H40N2O·H2O, the outer two six‐membered rings are in chair conformations, while the central ring is in an 8β,9α‐half‐chair conformation. The five‐membered ring adopts a 13β‐envelope conformation and the cyano­benzyl­idene moiety has an E configuration with respect to the hydroxyl group at position 17. The steroid nuclei are linked by intermolecular O—H?O and O—H?N hydrogen bonds to form a molecular network. The molecular packing has an interesting feature, with the steroids aligned parallel to the b axis, forming a closed loop through hydrogen bonds linked via water mol­ecules.  相似文献   

4.
The structure of the adduct of eucarvone with nitro­so­benzene, C16H19NO2, is reported. The [3.2.2] bicyclic system corresponds to two seven‐membered rings in boat and distorted chair conformations and a six‐membered ring that adopts a distorted boat conformation. No conjugation is observed between the phenyl group and the N—O system. The packing is directed mainly by a C?O hydrogen bond, C—H?O‐(1 ? x, ?y, z) and by intermolecular C—H?π interactions.  相似文献   

5.
In the title compound, C29H42O4·H2O, cyclo­hexane rings A and B are in the sofa conformation, ring C is in a chair conformation and the five‐membered ring D is in an envelope conformation. The structure is stabilized by inter‐ and intramolecular C—H?O and O—H?O hydrogen bonds.  相似文献   

6.
The asymmetric unit of the title compound, C22H31N3O4·H2O, incorporates one water mol­ecule, which is hydrogen bonded to the 3‐oxo O atom of the indolizidinone system. The two rings of the peptidomimetic mol­ecule are trans‐fused, with the six‐membered ring having a slightly distorted half‐chair conformation and the five‐membered ring having a perfect envelope conformation. The structure is stabilized by intermolecular O—H?O interactions between the water and adjacent peptide mol­ecules, and by N—H?O interactions between the peptide mol­ecules, which link the mol­ecules into infinite chains.  相似文献   

7.
The title compound, C32H45N2O+·Br?·0.5H2O, has the outer two six‐membered rings in chair conformations, while the central ring is in an 8β,9α‐half‐chair conformation. The five‐mem­bered ring of the steroid nucleus adopts a slightly deformed 14α‐envelope conformation. The pyridyl­methyl­ene moiety has an E configuration with respect to the hydroxyl group at position 17. The structure is stabilized by a network of O—H?Br‐type intermolecular hydrogen bonds.  相似文献   

8.
The ent‐kaurene diterpene in the title compound, 7‐epican­dicandiol ethanol solvate, C20H32O2·C2H6O, was isolated from the aerial parts of Sideritis ozturkii Aytaç & Aksoy. The mol­ecule has the usual conformation and stereochemistry found in related ent‐kaurene derivatives. The methyl‐substituted ring junction has a trans arrangement and the other junction is cis. The six‐membered rings have chair or slightly distorted chair conformations and the five‐membered ring has an envelope conformation. Inter­molecular hydrogen bonds link the 7‐epicandicandiol and ethanol mol­ecules into two‐dimensional networks, part of which comprise co‐operative O—H⋯O—H⋯O—H⋯ chains.  相似文献   

9.
The title compound, C23H15Cl2NO3, crystallizes with two independent mol­ecules in the asymmetric unit. The chroman­one moiety consists of a benzene ring fused with a six‐membered heterocyclic ring which adopts a sofa conformation. The five‐membered spiro­isoxazoline ring is in an envelope conformation. The p‐chloro­phenyl rings bridged by the five‐membered ring are nearly perpendicular to each other. The chromanone moiety of one mol­ecule packs into the cavity formed by the p‐chloro­phenyl rings of a second mol­ecule through the formation of C—H?π interactions. The structure is stabilized by weak C—H?O, C—H?Cl and C—H?π interactions.  相似文献   

10.
The title compound, alternatively called 24‐nor‐5β‐chol‐22‐ene‐3β,7α,12α‐triyl triformate, C26H38O6, has a cis junction between two of the six‐membered rings. All three of the six‐membered rings have chair conformations that are slightly flattened and the five‐membered ring has a 13β,14α‐half‐chair conformation. The 3β, 7α and 12α ring substituents are axial and the 17β group is equatorial. The 3β‐formyl­oxy group is involved in one weak intermol­ecular C—H⋯O bond, which links the mol­ecules into dimers in a head‐to‐head fashion.  相似文献   

11.
In the title compound, C18H16N2O4, the piperidine ring adopts a chair conformation, lying on an inversion centre. The 4‐hydroxy­benzyl groups are in quasi‐axial positions. A two‐dimensional network is formed through N—H?O and O—H?O intermolecular hydrogen bonds and C—H?O interactions.  相似文献   

12.
In the title compound, C13H14BN3O, the aziridine ring is an almost equilateral triangle, the C—C distance being slightly shorter than the C—N distances, probably because of the dative B—N bond. The five‐membered ring, composed of two C atoms and N, B and O atoms, is fused with the aziridine ring to form a six‐membered ring with a chair conformation.  相似文献   

13.
In the mol­ecule of the title compound, C13H18O3, there is a syn relationship between the two vicinal methyl groups. The six‐membered ring adopts a chair conformation, with one equatorial and two axial groups, and the furyl group is almost parallel to the ketone group. Intermolecular hydrogen bonds [O—H?O=C 2.814 (3) Å] form chains along [100].  相似文献   

14.
In the title cocrystal, 2‐aminopyrimidine–(+)‐camphoric acid (1/1), C4H5N3·C10H16O4, the 2‐amino­pyrimidine forms two eight‐membered hydrogen‐bonded rings with two different camphoric acid mol­ecules. This results in infinite wave‐like chains of mol­ecules in which neighbouring chains are connected by weak C—H?O contacts. The five‐membered ring in the acid mol­ecule adopts a half‐chair conformation.  相似文献   

15.
The title compound, C15H16N2O, crystallizes in the space group P212121 with Z′ = 1. The seven‐membered ring adopts a chair‐type conformation with the hydroxy and pyridyl substituents in equatorial sites. Molecules are linked into a three‐dimensional framework structure by a combination of O—H...N, C—H...O and C—H...π(arene) hydrogen bonds, but N—H...O and N—H...π(arene) interactions are absent from the structure. Comparisons are made with some related compounds.  相似文献   

16.
In the title compound, C24H18ClNO2, the phenyl ring and the tetralone moiety are approximately orthogonal to the isoxazoline ring. The isoxazoline ring adopts an envelope conformation, while the cyclo­hexenone ring of the tetralone moiety has an intermediate sofa/half‐chair conformation. In this structure, one C—H?N intermolecular and two C—H?O intramolecular hydrogen bonds occur; the H?A distances are 2.60, and 2.35 and 2.57 Å, respectively. The mol­ecules are held together by an intermolecular C—H?N hydrogen bond, forming a one‐dimensional chain along the [100] direction.  相似文献   

17.
In the title compound, 4‐(3β‐hydroxy‐17‐oxoandrost‐5‐en‐16‐ylidenemethyl)benzonitrile, C27H31NO2, rings A and C of the steroid nucleus are in chair conformations. The central six‐membered ring B is in an 8β,9α‐half‐chair conformation, while the five‐membered ring D adopts a 13β,14α‐half‐chair conformation. The cyano­benzyl­idene moiety has an E configuration with respect to the carbonyl group at position C17. The dihedral angle between the planes of the steroid nucleus and the cyano­benzyl­idene moiety is 22.61 (15)°. Intermolecular O—H⃛N hydrogen bonds formed between the hydroxyl group of the steroid and the N atom of the cyano­benzyl­idene moiety of symmetry‐related mol­ecules link the steroid mol­ecules into chains which run parallel to the b axis.  相似文献   

18.
The six‐membered ring of the norbornene moiety in the title compound, C18H18N4O4, is in a slightly distorted boat conformation, and the two five‐membered rings within it adopt envelope conformations. The structure is stabilized by inter‐ and intramolecular N—H?O hydrogen bonds.  相似文献   

19.
The title compound, C8H19NO7P2, is a member of the bis­phosphonate family of therapeutic compounds. PHPBP has inner‐salt character, consisting of a negatively charged PO3 group and a positively charged N atom. The six‐membered piperidine ring adopts an almost‐perfect chair conformation. The hydroxyl group and the N atom have gauche and trans conformations in relation to the O—C—C—C—N backbone, respectively. Hydrogen bonding is the main contributor to the packing in the crystal, which consists of head‐to‐head dimers formed through phosphonyl–phosphonyl hydrogen bonds, while O—H⋯O and N—H⋯O interactions join the dimers into a plane parallel to crystallographic b and c axes.  相似文献   

20.
In the title compound, C11H15O6P, the six‐membered dioxa­phospho­rinane ring of the cyclic phosphate triester exists in a distorted chair conformation, with the phenoxy group in an axial position. The phenyl ring and both methoxy groups are in a transgauche orientation with respect to the 1,3,2‐di­oxa­phospho­rinane ring. In the phosphate group, a significant deformation from the ideal tetrahedral shape is observed. The crystal structure is stabilized by a three‐dimensional network of C—H⋯O interactions.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号