Isomerization of S-2-hydroxyalkyl esters of cyclic phosphorus thioacids

Conclusions The S-2-hydroxyalkyl esters of cyclic P(V) thioacids, which were obtained by reacting a cyclic phosphorus monothioacid with an alkylene oxide, are converted to the 2-mercaptoalkyl esters of cyclic phosphorus acids independent of the size of the ring.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 11, pp. 2594–2596, November, 1980.     

Synthesis of S-β-aryl(benzyl)mercaptoethyl esters of phosphorus thioacids

Conclusions The S-3-aryl(benzyl)mercaptoethyl esters of the diethyl- and dihexylthiophosphoric acids, and of the O-ethyl-, O-butyl-, O-cyclohexylmethyl-, and O-ethylphenylthiophosphonic acids, were synthesized.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 2, pp. 434–436, February, 1984.     

Reaction of N-chloromethyldiethylamine,N-chloromethylbenzamide,and N-chloromethylphthalimide with esters of trivalent phosphorus thioacids

Conclusions N-Chlororaethylbenzamide and N-chloromethylphthalimide react with S-butyldiphenylthiophosphinite at the P atom. The reaction of S,S-dibutylphenyldithiophosphonite with N-chloromethylphthalimide proceeds preferentially at the P atom, and with N-chloromethylbenzamide at the S atom. With increase in the polarity of the C-Cl bond in the N-chloromethyldiethylamine > N-chloromethylbenzamide > N-chloromethylphthalimide series, the tendency to react at the S atom increases.Translated from Izvestiya Akademli Nauk SSSR, Seriya Khimicheskaya, No. 1, pp. 178–182, January, 1985.     

Poly(amino acid) derivatives of cyclotriphosphazene with luminescent fragments

Poly(amino acid)s with a central triphosphazene cycle and a peripheral pyrene moiety were synthesized from hexakis(4-aminophenoxy)cyclotriphosphazene and 1-pyrenebutanoic acid and have been characterized. The introduction of the luminophore resulted in the formation of highly ordered structures containing fragments with three α helices in the trans position to the phosphazene cycle. The character of luminescence spectra suggests the presence of pyrene dimers; their appearance may be associated with the intermolecular aggregation of peptide chains with chromophore end groups. The DSC data revealed the glass transition due to the freezing out of the mobility of side chains, as well as an alteration in the helix type of the poly(amino acid) fragments.     

Esters of thioacids of trivalent phosphorus

Conclusions The acid halides of the esters of thiophosphonous acids react with,-unsaturated ketones to give 2-thiono-1,2-oxa-4-phospholene derivatives.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 12, pp. 2765–2768, December, 1972.     

Inhibition of cholinesterases by S-β-aryl(benzyl)mercaptoethyl esters of phosphorus thioacids

Conclusions S--Aryl(benzyl)mercaptoethyl esters of monothioacids of pentavalent phosphorus are highly effective inhibitors of cholinesterases with a combined type of action.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 3, pp. 648–652, March, 1986.     

Nucleophilic addition of amino acid esters to nitrilium derivatives of closo-decaborate anion

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New methods of synthesis of boron,germanium, and tin derivatives of pentavalent phosphorus thioacids

The reactions of S‐trimethylsilyl esters of S‐propyl‐4‐methoxyphenyltrithiophosphonic, bis(dialkylamido)dithiophosphoric, and S‐ethyl‐diethylamidotrithiophosphoric acids with trialkyl borates, triorganylbromogermanes, trimethyl(isobutylthio)germane, and trialkylchlorostannanes were studied. On the basis of these studies, new methods of synthesizing S‐boron, S‐germyl, and S‐stannyl derivatives of pentavalent phosphorus thioacids were developed. S‐Diethylaminomethyl O‐isopropyl‐4‐ethoxyphenyldithiophosphonate was obtained by the reaction of the diisopropylboron derivative of the corresponding dithiophosphonic acid with the aminal 6 . © 2002 John Wiley & Sons, Inc. Heteroatom Chem 13:27–35, 2002; DOI 10.1002/hc.1103