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1.
An efficient synthesis of 2-(3-alkyl-4-oxo-2- thioxo-1,3-thiazinan-5-yl)acetic acids is described via a three-component reaction
between primary amines, CS2, and itaconic anhydride. 相似文献
2.
Abstract
In this study, we present a convenient and efficient method for the synthesis of novel, highly substituted 2-vinyl furans using a three-component reaction. The zwitterions generated from the reaction of isocyanides and dialkyl acetylenedicarboxylates are reacted with trans-cinnamoyl chlorides to produce the desired products in good yields. 相似文献3.
Francisco Carrión Sofia H. Pettersson Jordi Rifá Joan Farran Xavier Batllori José I. Borrell Jordi Teixidó 《Molecular diversity》2010,14(4):755-762
A protocol allowing the regiospecific synthesis of both positional isomers of 4,6-disubstituted 2-dicyanomethylene-1,2-dihydropyridin-3-carbonitriles,
precursors of 1,6-naphthyridines, is presented. Thus, treatment of enaminoketones with the propanedinitrile dimer yields one
regioisomer while the treatment of the corresponding (3-chloro-allylidene)-dimethylammonium perchlorates (easily obtained
from enaminoketones and POCl3), in which the nature of the reactive centers is inverted with respect to the enaminoketone, yields the other regioisomer. 相似文献
4.
Molecular Diversity - A straight forward and highly efficient one-pot annulation of 2-aminobenzothiazole, (E)-N-methyl-1-(methylthio)-2-nitroethenamine, and aldehydes in the presence of FeF3 is... 相似文献
5.
Yavari I Anary-Abbasinejad M Nasiri F Djahaniani H Alizadeh A Bijanzadeh HR 《Molecular diversity》2005,9(1-3):209-213
The reaction of dibenzoylacetylene and enaminocarbonyl compounds leads to 3-alkylidene-2,3-dihydro-1H-pyrrol-2-ol derivatives in nearly quantitative yields. The reaction of this heterocyclic system with alcohols in the presence of a catalytic amount of HCl produces highly functionalized pyrroles in good yields. 相似文献
6.
Ruthenium catalyzed ring opening cross-metathesis of resin-bound bicyclic alkenes with terminal aryl olefins was utilized
for the construction of a combinatorial library containing highly functionalized cyclopentane derivatives. The technology
described herein represents a convergent method for the diastereospecific synthesis of unique cyclopentane molecular scaffolds
useful for exploratory medicinal chemistry.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
7.
Zhenghua Wang Hui Wang Lingling Wang Ling Pan 《Journal of Physics and Chemistry of Solids》2009,70(3-4):719-722
Single-crystalline Cu2O hollow nanocubes have been successfully synthesized via a simple wet chemical route in the absence of any surfactants or templates. By studying the growth process of the Cu2O hollow nanocubes, we found that the Cu2O hollow nanocubes were formed through a reducing and simultaneously etching process. The speed of reducing Cu(OH)2 into Cu2O was much faster than the speed of etching Cu2O. As a result, Cu2O solid nanocubes were firstly formed, and then the solid nanocubes were gradually etched into hollow nanocubes. 相似文献
8.
《Current Applied Physics》2018,18(11):1255-1260
In this work, a green and simple one-pot route was developed for the synthesis of highly fluorescent amino-functionalized graphene quantum dots (a-GQDs) via hydrothermal process without any further modification or surface passivation. We synthesized the a-GQDs using glucose as the carbon source and ammonium as a functionalizing agent without the use of a strong acid, oxidant, or other toxic chemical reagent. The as-obtained a-GQDs have a uniform size of 3–4 nm, high contents of amino groups, and show a bright green emission with high quantum yield of 32.8%. Furthermore, the a-GQDs show effective fluorescence quenching for Cu2+ ions which can serve as effective fluorescent probe for the detection of Cu2+. The fluorescent probe using the obtained a-GQDs exhibits high sensitivity and selectivity toward Cu2+ with the limit of detection as low as 5.6 nM. The mechanism of the Cu2+ induced fluorescence quenching of a-GQDs can be attributed to the electron transfer by the formation of metal complex between Cu2+ and the amino groups on the surface of a-GQDs. These results suggest great potential for the simple and green synthesis of functionalized GQDs and a practical sensing platform for Cu2+ detection in environmental and biological applications. 相似文献
9.
10.
Pallabi Borah P. Seetham Naidu Swarup Majumder Pulak J. Bhuyan 《Molecular diversity》2014,18(4):759-767
One-pot multi-component reaction of 3-cyanoacetyl indole, aromatic aldehydes and ethyl acetoacetate in the presence of \(\hbox {InCl}_{3}/\hbox {NH}_{4}\) OAc under microwave irradiation for 2–7 min afforded novel and highly functionalized 3-(pyranyl)- and 3-(dihydropyridinyl)indole derivatives, respectively, in good yield. 相似文献
11.
Majid M. Heravi Mina Saeedi Yahya S. Beheshtiha Hossein A. Oskooie 《Molecular diversity》2011,15(1):239-243
Abstract
One-pot synthesis of different benzochromeno-pyrazole derivatives has been reported via reaction of aldehydes, 3-methyl-1H-pyrazol-5(4H)-one and α-naphthol/β-naphthol in the presence of sulfamic acid. 相似文献12.
The reaction between ketenimine intermediates [generated from terminal alkynes and sulfonyl azides], diethyl azadicarboxylate, and sodium arylsulfinates in N, N-dimethylformamide at room temperature, affords ethyl 2,3-dihydro-3-oxo-4-phenyl-2-tosyl-5-(tosylamino)pyrazole-1-carboxylates in moderate-to-good yields. When diisopropyl azadicarboxylate was used as the ester component, diisopropyl 1-arylsulfonyl-2-{[aryl(alkyl)sulfonyl]-2-phenylethanimidoyl}-1,2-hydrazinedicarboxylates were obtained. 相似文献
13.
Kushal C. Lekhok Debajyoti Bhuyan Dipak Prajapati Romesh C. Boruah 《Molecular diversity》2010,14(4):841-846
An environmentally friendly and highly efficient procedure for the preparation of quinolines and fused polycyclic quinolines
has been developed by a simple Friedlander annulation reaction of 2-aminoaryl ketone with carbonyl compounds in presence of
zinc triflate under microwave irradiation and solvent-free conditions. The reaction also proceeds effectively when In(OTf)3 was used in lieu of Zn(OTf)2 as the catalyst. The catalyst can be recovered after the reaction and reused efficiently in subsequent runs. 相似文献
14.
15.
Swapnil R. Sarda Jagpal D. Kale Sunil K. Wasmatkar Vijay S. Kadam Pravin G. Ingole Wamanrao N. Jadhav Rajendra P. Pawar 《Molecular diversity》2009,13(4):545-549
Chalcones on condensation with malononitrile and ammonium acetate in the presence of ionic liquid ethylammonium nitrate affords
the corresponding 2-amino-4, 6-diphenylpyridine-3-carbonitrile in excellent yield. The ionic liquid is recycled and reused
several times. 相似文献
16.
With ultrasonic irradiation as assistance, highly dispersed MoO(3) nanospheres were synthesized using silane coupling agent 3-mercaptopropyltrimethoxysilane HS-(CH(2))(3)Si(OCH(3))(3) (MPTS) as figuration agent. The results of X-ray powder diffractometer (XRD) showed that the precursor was hexagonal molybdenum oxide hydrate (MoO(3).0.55H(2)O). It was converted into orthorhombic MoO(3) after annealed at 400 degrees C for 2h. Transmission electron microscopy (TEM) showed that MoO(3).0.55H(2)O and MoO(3) nanoparticles were spherical with particle-size distribution of ca. 30-80 nm and 25-75 nm, respectively. Results indicated that MPTS and ultrasonic irradiation played important role in formation of highly dispersed MoO(3) nanospheres. X-ray photoelectron spectroscopy (XPS) was also adopted to confirm the growth mechanism. The possible cause of formation was based on dispersion function of ultrasonic irradiation and figuration of MPTS. 相似文献
17.
Juan-Juan Zhang Xian Feng Xue-Cheng Liu Zhi-Bin Huang Da-Qing Shi 《Molecular diversity》2014,18(4):727-736
An efficient and diastereoselective synthetic procedure for highly functionalized tetrahydroacenaphtho[1,2- \(b\) ]indolone derivatives was successfully developed by the three-component reaction of acenaphthequinone, enaminones, and barbituric acid in the presence of a catalytic amount of L-proline. This method has the advantages of convenient operation, excellent yields, mild reaction conditions, and environmental friendliness. 相似文献
18.
B.?Beck S.?Srivastava K.?Khoury E.?Herdtweck Alexander?D?mling 《Molecular diversity》2010,14(3):479-491
We designed two novel thiolactone scaffolds. Both scaffolds can be accessed by a convergent Ugi multicomponent reaction (MCR)
and are, thus, amenable to library synthesis. Design, stereoselectivity, structures, full experimental details, and virtual
libraries will be reported. 相似文献
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20.
Highly dispersed carbonaceous spheres with sulfonic acid groups were successfully prepared from glucose by hydrothermal method.
Transmission electron microscopy (TEM) showed the as-synthesized carbonaceous materials were uniform, spherical in shape with
an average diameter of about 450 nm. Fourier transform infrared (FT-IR) proved that –SO3H, –COOH, OH groups were grafted on the surface of the carbonaceous spheres during the sulfonation. Interestingly, the functionalized
carbonaceous spheres exhibited high dispersibility in the polar solvent due to the hydrophilic groups on the surface. The
mechanism of the formation for the carbonaceous spheres was also discussed based on the analysis of structure and composition.
At last, the functionalized carbonaceous spheres were employed as solid acid to hydrolyze starch and cellulose. By comparison,
the as-synthesized catalyst showed considerable high yield of glucose. 相似文献