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1.
    
When faced with a problem to be solved by running designed experiments we should first think of what strategy should be used for the experimentation. One aspect of successful experimental strategy is how to use screening experiments in practice. In this article the authors share their combined experiences of more than 90 years in using designed experiments in which screening experiments are an integral part of the strategy. Along the way the benefits of running screening experiments and why they work are discussed. Topics such as the Pareto principle applied to experimentation and the robustness of screening designs to assumptions are addressed. Case studies, tips, traps, and guidelines are provided. What emerges is a holistic approach to experimentation that results in practicing scientists and engineers getting the right data in the right amount at the right time.  相似文献   

2.
正交平衡区组设计(或广义正交表)的数据分析类似于正交拉丁方(或正交表)的数据分析.利用类似于正交表数据分析中的投影矩阵的正交分解技术,研究正交平衡区组设计的统计分析模型,给出了方差分析中的二次型以及各因子的二次型的分布性质,从而给出正交平衡区组设计统计模型中的方差分析方法.  相似文献   

3.
正交设计的最新发展和应用-回归分析在正交设计的应用   总被引:6,自引:0,他引:6  
正交设计有许多新发展,本系列讲座介绍其中的一些便于应用的结果,共有四部份:回归分析在正交设计中的应用,均匀正交设计,正交设计的D-最优性,以及正交设计的投影性质。本讲强调回归分析用于正交设计的建模、估计、减少参数数目方面的应用  相似文献   

4.
正交平衡区组设计(或者广义正交表)是一种类似于正交拉丁方(或者正交表)的新设计,但试验次数大幅减少.定义了一种基于正交相遇平衡区组设计(或者广义正交表)的统计分析模型,根据这个模型,给出了参数的最小二乘估计的矩阵形式.  相似文献   

5.
A proof of the following conjecture of Jungnickel and Tonchev on quasi-multiple quasi-symmetric designs is given: Let D be a design whose parameter set (v,b,r,k,) equals (v,sv,sk,k, s) for some positive integer s and for some integers v,k, that satisfy (v-1) = k(k-1) (that is, these integers satisfy the parametric feasibility conditions for a symmetric (v,k,)-design). Further assume that D is a quasi-symmetric design, that is D has at most two block intersection numbers. If (k, (s-1)) = 1, then the only way D can be constructed is by taking multiple copies of a symmetric (v,k, )-design.  相似文献   

6.
正交平衡区组设计(或者广义正交表)是一种类似于正交拉丁方(或者正交表)的新设计,但试验次数大幅减少.通过对正交平衡区组设计统计分析模型参数估计的分布特征进行了深入研究.研究发现,在试验数据正态性的情况下,各种参数估计也服从正态分布,并且各种参数的最小二乘估计都是无偏的,得到了各种参数估计的方差和独立性性质.  相似文献   

7.
由于试验材料、费用和时间等条件的限制,仅有单次重复试验的三水平析因设计经常要应用在农业、工业和医学临床试验等领域。例如,在医学临床试验中,为找到影响治疗关节炎效果的重要因子和最佳治疗方案需要考虑2个三水平的因子:A(药物治疗)和B(运动治疗),由于只能找到9位病情相似的病人进行试验,故只能实施仅有单次重复试验的三水平析因设计3~2。不幸的是,交互作用A×B也可能存在,这样就没有剩余自由度用于估计误差的方差,从而通常的方差分析方法不再能用于数据分析。针对上述问题,本文提出了三个基于均方误差的检验统计量用于分析单次重复试验的三水平析因设计。通过实例表明用这些方法不仅能检验所考虑因子的主效应,而且还能同时检验交互效应。相应检验所用的一些常用临界值提供在附录中。并且,还通过大量的模拟研究对所提出的三个检验方法进行了比较。结果显示,T_~((3))检验在三个检验方法中具有最大的功效。  相似文献   

8.
正交平衡区组设计(或者广义正交表)的数据分析类似于正交拉丁方(或者正交表)的数据分析,但试验次数大幅减少.引入了相遇平衡区组设计矩阵象的概念,定义了一种基于正交相遇平衡区组设计(或者广义正交表)的统计分析模型,根据这个模型,推导得到了参数的最小二乘估计.  相似文献   

9.
计算机仿真模型广泛应用于工业工程等领域,借助真实的物理观测对计算机模型的校准参数进行估计,可以提高计算机模型的仿真精度.已有文献指出,当物理试验的试验点独立同分布于均匀分布时,计算机模型校准参数的L2估计半参数有效.然而真实的物理试验点往往不满足独立同分布于均匀分布这一条件,文章证明了在固定的试验点下,较准参数L2估计的相合性和渐近正态性,并通过数值模拟验证了L2估计的收敛速度.  相似文献   

10.
In this article, we propose localized implementations of the iterative proportional scaling (IPS) procedure by the strategy of partitioning cliques for computing maximum likelihood estimations in large Gaussian graphical models. We first divide the set of cliques into several nonoverlapping and nonempty blocks, and then adjust clique marginals in each block locally. Thus, high-order matrix operations can be avoided and the IPS procedure is accelerated. We modify the Swendsen–Wang Algorithm and apply the simulated annealing algorithm to find an approximation to the optimal partition which leads to the least complexity. This strategy of partitioning cliques can also speed up the existing IIPS and IHT procedures. Numerical experiments are presented to demonstrate the competitive performance of our new implementations and strategies.  相似文献   

11.
Let a linear regression model be given with an experimental region [a, b] R and regression functions f 1, ..., f d+1 : [a, b] R. In practice it is an important question whether a certain regression function f d+1, say, does or does not belong to the model. Therefore, we investigate the test problem H 0 : "f d+1 does not belong to the model" against K : "f d+1 belong to the model" based on the least-squares residuals of the observations made at design points of the experimental region [a, b]. By a new functional central limit theorem given in Bischoff (1998, Ann. Statist. 26, 1398–1410), we are able to determine optimal tests in an asymptotic way. Moreover, we introduce the problem of experimental design for the optimal test statistics. Further, we compare the asymptotically optimal test with the likelihood ratio test (F-test) under the assumption that the error is normally distributed. Finally, we consider real change-point problems as examples and investigate by simulations the behavior of the asymptotic test for finite sample sizes. We determine optimal designs for these examples.  相似文献   

12.
成平 《东北数学》2001,17(4):407-422
In this paper, we consider the location model Y=θ e,where θ is an unknown parameter, and e is the error belonging to the interval [a, b]. We assume that e has the following density function.  相似文献   

13.
A powerful data transformation method named guided projections is proposed creating new possibilities to reveal the group structure of high-dimensional data in the presence of noise variables. Using projections onto a space spanned by a selection of a small number of observations allows measuring the similarity of other observations to the selection based on orthogonal and score distances. Observations are iteratively exchanged from the selection creating a nonrandom sequence of projections, which we call guided projections. In contrast to conventional projection pursuit methods, which typically identify a low-dimensional projection revealing some interesting features contained in the data, guided projections generate a series of projections that serve as a basis not just for diagnostic plots but to directly investigate the group structure in data. Based on simulated data, we identify the strengths and limitations of guided projections in comparison to commonly employed data transformation methods. We further show the relevance of the transformation by applying it to real-world datasets.  相似文献   

14.
Recently pooling designs have been used in screening experiments in molecular biology. In some applications, the property to be screened is defined on subsets of items, instead of on individual items. Such a model is usually referred to as the complex model. In this paper we give an upper bound of the number of tests required in a pooling design for the complex model (with given design parameters) where experimental errors are allowed.  相似文献   

15.
16.
Abstract

In a longitudinal study, individuals are observed over some period of time. The investigator wishes to model the responses over this time as a function of various covariates measured on these individuals. The times of measurement may be sparse and not coincident across individuals. When the covariate values are not extensively replicated, it is very difficult to propose a parametric model linking the response to the covariates because plots of the raw data are of little help. Although the response curve may only be observed at a few points, we consider the underlying curve y(t). We fit a regression model y(t) = x Tβ(t) + ε(t) and use the coefficient functions β(t) to suggest a suitable parametric form. Estimates of y(t) are constructed by simple interpolation, and appropriate weighting is used in the regression. We demonstrate the method on simulated data to show its ability to recover the true structure and illustrate its application to some longitudinal data from the Panel Study of Income Dynamics.  相似文献   

17.
We consider a system modelling the motion of a piston in a cylinder filled by a viscous heat conducting gas. The piston is moving longitudinally without friction under the influence of the forces exerted by the gas. In addition, the piston is supposed to be thermally insulating (adiabatic piston). This fact raises several challenges which received a considerable attention, essentially in the statistical physics literature. We study the problem via the methods of continuum mechanics, specifically, the motion of the gas is described by means of the Navier–Stokes–Fourier system in one space dimension, coupled with Newton's second law governing the motion of the piston. We establish global in time existence of strong solutions and show that the system stabilizes to an equilibrium state for t.  相似文献   

18.
The intent of the home reversion plan for retired homeowners in United Kingdom is to help house-rich but cash-poor seniors by the way of releasing their home equity into cash so as to meet living expenses and continue to enjoy the right to live in their home until their death. We present multiple finite state Markov models to price the continuous annuities of insurance policies relevant to home reversion plan for a pair of insureds (meaning husband and wife). Our modeling assumes that the home value follows a geometric Brownian motion. By applying the principle of equivalent utility, we derive the partial differential equation system that the indifferent annuities satisfy under the exponential utility function, and find their explicit representations. Furthermore, we employ an explicit finite difference scheme to calculate the numerical solution and discuss the impacts of the risk aversion of insurer, the volatility of home value, and the interest rate on the annuities of home reversion plan for a couple. We observe that these results reflect our intuition.  相似文献   

19.
The instability property of the standing wave uω(t, x) = eiωtφ(x) for the Klein–Gordon– Hartree equation  相似文献   

20.
In the present paper we describe the use of group actions, double cosets and homomorphisms in the constructive theory of discrete structures, as we found it useful from both a theoretical and a practical point of view. By means of examples we should like to demonstrate that these methods are useful both as unifying principles and as efficient methods for applications.  相似文献   

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