共查询到19条相似文献,搜索用时 174 毫秒
1.
芳香醛与3—甲基—1苯基—5—吡唑啉酮固相缩合反应的研究 总被引:7,自引:0,他引:7
研究了芳香醛与3-甲基-1-苯基-5-吡唑啉酮在室温固相、熔融状态及Lewis酸催化下的缩合反应,分别得到4,4'-甲太-双(3-甲基-1-苯基-5-吡唑啉酮)2-4-芳甲太-3-甲基-1-苯基-5-吡唑啉1.实验表明,在固体状态下,2主要以烯醇式存在,受势时或在溶液中两者可相互转化。 相似文献
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铽与4—酰代吡唑啉酮—5的三元配合物的合成与荧光性质 总被引:4,自引:0,他引:4
合成并表征了一系列铽与含不同4-酰代的1-苯基-3-甲基-吡唑啉酮-5的三元配合物Tb9L)3.2H2O和Tb(L)3.Dipy「L=1-苯基-3-甲基-4-乙酰基吡啥林酮-5(PMAP),1-苯基-3-甲基-4-丙酰基吡唑啉酮-5(PMPP),1-苯基-3-甲基-4-异丁酰基吡唑啉酮-5(PMIBP),1-苯基-3-甲基-4-特戊酰基吡唑啉酮-5(PMPVP),1-苯基-3-甲基-4-苯甲酰基吡 相似文献
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报道了苯偶酰及其衍生物,对二甲氨基苯偶姻、邻苯二甲酰亚胺与1-苯基-3-甲基-5-吡唑啉酮的固相热反应研究;这个热反应以较高的选择性生成1:1缩全产物的一种异构体,通过1R、HNMR、MS和元素分析确定了新产物的结构,并通过X射线衍分析确定了其中一个产物的构型。 相似文献
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Villemin[1]曾报道KSF/蒙托土催化下微波促进1-苯基-3-甲基-5-吡唑啉酮(1)与醛2的缩合反应,李晓陆[2研究了该反应的固相缩合,Sun[3]报道了KF-Al2O3催化下甲醇溶液中的反应.本文采用绿色合成原则,无催化剂条件下无溶剂微波辐射及水中回流方法研究了此反应,得到两类化合物(图1).产物结构经1H NMR,13C NMR,MS及IR确证.实验发现辐射功率对产物有很大影响,高辐射功率下得到4-芳甲叉-3-甲基-1-苯基-5-吡唑啉酮(3),低辐射功率得到4,4′-芳甲叉-双(3-甲基-1-苯基-5-吡唑啉酮)(4);水相反应同时得到两种产物,以产物3为主(表1).产物结构与反应物配比无关. 相似文献
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1-苯基-3-甲基-5-吡唑啉酮与二羰基化合物的固相反应研究 总被引:1,自引:0,他引:1
报道了苯偶酰及其衍生物、对二甲氨基苯偶姻、邻苯二甲酰亚胺与1-苯基-3-甲基-5-吡唑啉酮的固相热反应研究;这个热反应以较高的选择性生成1:1缩合产物的一种异构体,通过IR、1HNMR、MS和元素分析确定了新产物的结构,并通过X射线衍射分析确定了其中一个产物的构型。 相似文献
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DU Da-Ming MENG Shuang-Ming WANG Yong-Mei MENG Ji-Ben ZHOU Xiu-ZhongDepartment of Chemistry Nankai University Tianjin China 《中国化学》1995,13(6):520-524
The solid state reactions of p-nitroacetophenone,acetyl-ferrocene with indole were catalyzed by anhydrous zinc chloride or aluminum chloride,and gave exclusively the 1:2 condensation products.The solid state condensation of aromatic ketones with l-phenyl-3-methyl-5-pyrazolone was also investigated,and the 1:1 and 2:1 condensation products were obtained.The structures of eleven new products were determined by IR,MS,1H NMR and elemental analysis. 相似文献
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The solid state reaction of 3-methyl-1-phenyl-5-pyrazolone (MPP) with aromatic aldehydes and ke-tones benzil derivatives and imides,and the solid state Michael addition reaction of MPP with 4-arylidene-3-methyl-1-phenyl-5-pyrnzolone 2 were investigated.Some new solid state reactions between the reactants were found,from which a series of new compounds were obtained The structures of the products were identified by IR,1H NMR,MS,elemental analyses and also by X-ray crystal analysis,and the reaction mechanism of MPP with aromatic aldehydes and ketones was proposed 相似文献
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Abdel-Latif S. A. El-Roudi O. M. Mohamed M. G. K. 《Journal of Thermal Analysis and Calorimetry》2003,73(3):939-950
Infrared (IR), nuclear magnetic resonance (NMR), thermogravimetric analysis (TG), derivative thermogravimetric analysis (DTG),
differential thermal analysis (DTA) and molar conductivity studies have been carried out on the chelates of Mn(II), Co(II),
Ni(II), Cu(II) and Zn(II) with 3-methyl- and 3-phenyl-4-nitroso-5-pyrazolones. The solid chelates were synthesized, separated,
analyzed and their structures were elucidated. The data obtained show that almost all of the prepared chelates contain water
molecules in their coordination sphere. The initial stage in the thermal decomposition process of these chelates shows the
presence of water molecule, the second denotes to the intermediate products. The final decomposition products were found to
be the respective metal oxides. The NMR spectrum of 3-methyl-4-nitroso-5-pyrazolone ligand shows the existence of the oxime
rather than the nitroso form. 3-phenyl-4-nitroso-5-pyrazolone acts as a neutral bidentate ligand whereas 3-methyl-4-nitroso-5-pyrazolone
acts as monobasic bidentate ligand bonded to the metal ions through the two oxygen atoms of the carbonyl and nitroso groups.
The solid chelates prepared behave as non-electrolytes in DMF solution. The coordination numbers of the obtained chelates
using 3-methyl-4-nitroso-5-pyrazolone are four on applying the mole ratio 1:1 and six on using 1:2 mole ratio. In case of
using the ligand 3-phenyl-4-nitroso-5-pyrazolone the coordination number is six in both cases.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
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Xiao-Liu Li Yong-Mei Wang Teruo Matsuura Ji-Ben Meng 《Journal of heterocyclic chemistry》1999,36(3):697-701
The Michael addition reactions of indole to 4-arylidene-3-methyl-1-phenyl-5-pyrazolone 1 were investigated in the solid state, by which a series of new compounds, 1-aryl-1-(3-indolyl)-1-(3′-methyl-1′-phenyl-5′-pyrazolon-4′-yl)methanes 2 , were easily obtained. This provides a feasible method of preparing novel compounds containing two heterocyclic groups at the same carbon. 相似文献
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K. V. Mityurina V. G. Kharchenko L. V. Cherkesova 《Chemistry of Heterocyclic Compounds》1981,17(2):180-183
4-(3-Oxopropyl)-5-pyrazolone derivatives were obtained under mild conditions of alkaline catalysis by condensation of 1-phenyl-3-methyl-5-pyrazolone and substituted chalcones. During ionic hydrogenation of the products they undergo heterocyclization with the formation of 5,6-dihydropyrano[3,2-d]pyrazoles.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 245–248, February, 1981. 相似文献
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Yi HU Ping WEI Hua ZHOU Ping Kai OUYANG Zhen Chu CHEN 《中国化学快报》2006,17(3):299-301
The derivatives of pyrazolone are important class of antipyretic and analgesic compounds1. 1-Phenyl-3-methyl-4-arylmethylene-5-pyrazolones are very useful inter- mediates in the synthesis of substituted pyrazolones, generally, which were prepared by the c… 相似文献
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N. N. Tonkikh M. V. Petrova A. F. Mishnev K. V. Ryzhanova F. M. Avotin'sh A. Ya. Strakov 《Chemistry of Heterocyclic Compounds》2000,36(7):822-829
The corresponding 2,3-substituted 4(3H)-quinazolinones were obtained in the reactions of 2-methyl- and 2-phenyl-4-oxo-3,1-benzoxazines with 1-amino-1,2,4-triazole, 4-amino-2,3-dimethyl-1-phenyl-5-pyrazolone, 2-amino-5-ethyl-1,3,4-thiadiazole, 3-amino-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazole, 1-amino-3-cyano-4,6-dimethyl-2-pyridone, and 1-amino-3-cyano-6-phenyl-4-trifluoromethyl-2-pyridone. The formation of N-benzolyanthranilamides in the reactions of 2-phenyl-4-oxo-3,1-benzoxazine with 2-amino-5-ethyl-1,3,4-thiadiazole and 1-amino-3-cyano-6-phenyl-4-trifluoromethyl-2-pyridones was exceptional. The structures of two of the products have been confirmed by X-ray crystallography.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 936–943, July, 2000. 相似文献
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N. I. Pavlenko V. P. Marshtupa N. A. Klyuev B. P. Baskunov 《Chemistry of Heterocyclic Compounds》1981,17(8):808-812
The aminomethylation of oxindole, 1-phenyl-3-methyl-5-pyrazolone, and N-phenyl-rhodanine was studied. Derivatives of these CH acids were obtained as a result of aminomethylation. The addition products were subjected to acid and base hydrolysis; the corresponding arylidene derivatives are formed in the case of the products of aminomethylation of oxindole and 1-phenyl-3-methyl-5-pyrazolone, while thioglycolic acids are formed in the case of N-phenylrhodanine derivatives.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1088–1093, August, 1981. 相似文献