A chemical study of plants of the Mongolian flora lariside — A new scopoletin glycoside fromSalsola laricifolia

A new coumarin glycoside lariside — C₂₁H₂₆O₁₃, mp 155–156°C (from methanol) — has been isolated from the epigeal part ofSalsola laricifolia Turcz. et Litw. On the basis of acid hydrolysis and spectral characteristics the structure of lariside has been established as 7-[O--D-apiofuranosyl-(1 2)--D-glucopyranosyloxy]-6-methoxy-2H-1-benzopyran-2-one.Institute of Chemistry, Academy of Sciences of the Mongolian Peoples' Republic, Ultan-Bator. Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 288–291, May–June, 1986.     

Triterpene glycosides and their genins fromThalictrum foetidum. IV. Structure of cyclofoetigenin B

A glycoside isolated from the epigeal part ofThalictrum foetidum (Ranunculaceae) has yielded a new genin — cyclofoetigenin B — the structure of which has been established on the basis of chemical transformations and spectral characteristics as 24S-cycloartane-3,16,24,25,30-pentaol.Irkutsk Institute of Organic Chemistry of the Siberian Branch of the Academy of Sciences of the USSR. Institute of the Chemistry of Plant Substances of the Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 312–320, May–June, 1986.     

The structure of karakolidine

Summary As the result of a study of chemical transformations and spectral characteristics, for the new alkaloid karakolidine a lycoctonine skeleton with N-ethyl and C₄-methyl groups, hydroxy groups at C₁ (), C₈, C₁₀ (), and C₁₃, and a methoxy group at C₁₅ () has been established.Some peculiarities of the fragmentation of derivatives of karakoline and karakolidine under the action of electron impact have been found.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 481–486, July–August, 1975.     

Coumarins fromPhlojodicarpus sibiricus

Phlojodicarpin [8-(2,3-epoxy-1-hydroxy-3-methylbutyl)-7-methoxycoumarin, C₁₅H₁₆O₅, mp 143–145°C, [] _D ²⁵ -37.5°], and isophlojodicarpin [8-(1,2-epoxy-3-hydroxy-3-methylbutyl)-7-methoxycoumarin, C₁₅H₁₆O₅, mp 132–134°C, [] _D ²⁵ -102.5°] have been isolated from the epigeal part ofPhlojodicarpus sibiricus. The results of the IR, UV, PMR, and mass spectrometry of these compounds are given.Institute of Chemistry, Academy of Sciences of the Mongolian Peoples' Republic, Ulan-Bator. Irkutsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 47–49, January–February, 1981.     

Flavonoids of Thermopsis alterniflora

Summary From the lipophilic fraction of the substances from the herbage ofThermopsis alterniflora we have isolated a molecular compound of two flavonoids, one of which has been identified as chrysoeriol, while the second, with the composition C₁₆H₁₂O₅, mp 274–275°C, is a new isoflavone which we have called teralin. On the basis of spectral characteristics and the products of alkaline fusion, we have proposed for it the structure of 4,7-dihydroxy-2-methoxyisoflavone.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 140–144, March–April, 1975.     

Structures of dictysine and dehydrodictysine

From the results of an x-ray structural analysis of free dictysine it has been established that dictysine is an alkaloid of the denudatine type with an, , -triol system at C₁₅, C₁₆, and C₂₀. The structures of the acetonides of dictysine and dehydrodictysine formed from dictysine and dehydrodictysine, respectively, in the process of separating the combined alkaloids, have been shown.Institute of the Chemistry of Plant Substances, Academy of Sciences of Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 86–91, January–February, 1982.     

Berberis alkaloids. XXI. Intebrine — A new N-benzylisoquinoline alkaloid from Berberis integerrima

A new N-benzylisoquinoline alkaloid — intebrine, with the composition C₂₀H₁₉NO₇ — has been isolated fromBerberis integerrima Bunge. The spatial structure of intebrine has been reliably determined by the x-ray structural method (diffractometer, CuK radiation, 972 reflections, direct method, R=0.048). Its chemical behavior, spectral characteristics, and mass-spectrometric fragmentation under electrom impact have been studied.Andizhan State Medical Institute. Institute of the Chemistry of Plant Substances, Uzbekistan Republic Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedeninii, No. 1, pp. 65–70, January–February, 1993.     

Mass spectra and stereochemistry of some macrocyclic pyrrolizidine alkaloids

Conclusions On the basis of the results of a comparison of the mass spectra of macrocyclic pyrrolizidine alkaloids with a known configuration of the side chain (trichodesmine, monocrotaline) with the spectra of incanine, crispatine, and fulvine a hypothesis has been put forward on the relative positions of the substituents at C₂ and C₃ in the molecules of the three latter compounds.Order of the Red Banner of Labor Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 40–44, January–February, 1974.     

Circular dichroism of guaianolides and the products of their amination

The presence of an -oriented hydroxy group at C₈ in a guaianolide promotes the stereospecificity of the amination of an exomethylene bond linked with the -lactone grouping. The addition of morphiline and of piperidine to the exomethylene bond of the lactone ring of a guaianolide containing an -oriented hydroxy group at C₈ takes place with the preferential formation of the 11S isomer.Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 722–724, November–December, 1984.     

Structures of decorine and delcoridine

In order to confirm the structures of the alkaloids delcorine and delcoridine (O-demethyldelcorine) suggested previously, a direct passage has been performed from delcoridine to delcorine and from delcorine to delphatine. It has been shown that the configuration of C₁ - OCH₃ previously suggested for delcorine and delcoridine is incorrect — it should be .Institute of the Chemistry of Plant Substances of the Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 621–623, September–October, 1981.     

Spatial structures of the sesquiterpene germacrane lactones tanachin and tamirin

An x-ray investigation has been made of the sesquiterpene lactones tanachin and tamarin: diffractometer, CuK-radiation, 845 and 981 reflections, respectively, direct method, R factors 0.064 and 0.065. The conformations of both molecules are boat-boat with configurations of the¹D₁₄ and¹⁵D₅ types.Institute of the Chemistry of Plant Substances, Uzbek SSR Academy of Sciences, Tashkent. Institute of Bioorganic Chemistry, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodynkh Soedinenii, No. 2, pp. 198–204, March–April, 1989.     

Structure of severidinine

A new alkaloid, severidinine, with mp 145–147°C []_D –50.2°, C₁₉H₄₅NO₆, has been isolated from the epigeal part ofKoralkowia sewerzowii Regel. On the basis of the IR, PMR, and mass spectra of severidinine and its transformation products, and also passage to the known alkaloids severidine, the structure of 3-acetylseveridine has been established for severidinine.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 488–490, July–August, 1983.     

Phytoecdysteroids of plants of the genusSilene XIV. Brahuisterone fromSilene brahuica

A new ecdysteroid with the composition C₂₇H₄₄O₆ which has been called brahuisterone has been isolated from the epigeal part of the plantSilene brahuica Boiss. Its chemical and complete spatial structures have been established by spectral studies and the x-ray structural method (diffractometer, Cu-K radiations, 996 reflections, direct method, R=0.119).Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbekistan Republic, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 553–558, July–August, 1993.     

A chemical study of the roots ofFerula kopetdagensis

Summary Ferukrin and the new natural compound acetylferukrin C₂₆H₃₄O₆ have been isolated from the roots ofFerula kopetdagensis.The absolute configuration of ferukrin has been established on the basis of the results of a study of chemical and spectral characteristics and also by means of a passage to farnesiferol A.It has been shown that it is an epimer of deacetylkellerin at C₆.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 17–21, January–February, 1979.     

Terpenoids of the oleoresin of the Schrenk spruce

New nitrogen derivatives possessing the activity of plant growth regulators have been synthesized from the readily available natural terpenoids - and -pinenes.Institute of Chemistry, Moldavian SSR Academy of Sciences, Kishinev. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 338–342, May–June, 1990.     

The structure of cycloglobiceposide B fromAstragalus globiceps

Two known compounds of the cycloartane series—cyclosieversiosides C and G—and the new glycoside cycloglobiceposide B—24R-cycloartane-3,6,16,24,25-pentaol 16,25-di-O--D-glucopyranoside 3-O--D-xylopyranoside—have been isolated from the roots ofAstragalus globiceps Bunge. The structures of the glycosides were established on the basis of the results of enzymatic and total hydrolysis and also of¹H and¹³C NMR spectra.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (371) 120 64 75. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 216–219, March–April, 1999.     

Spatial structure of akiferin from Ferula akitschkensis

The spatial structure of the carotane ester akiferin has been established by the x-ray structural method (diffractometer, CuK radiation, 1109 reflections, direct method, R=0.084). Using the method of molecular mechanics, possible conformational states of the free akiferin molecule have been calculated by rotating the para-methoxybenzoate [sic] moiety of the molecule relative to the C6-O axis.Institute of Chemistry of Plant Substances, Uzbekistan Republic Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedeninii, No. 1, pp. 96–100, January–February, 1993.     

Influence of thionin on the structure of a bilayer and on the intermembrane exchange of lipid material

It has been shown that in lipid dispersions thionin causes the formation of heterogeneous structures with the production of lipid-enriched clusters melting at elevated temperatures. This effect of thionin depends on the type of acidic lipid. It has also been established that thionin causes the aggregation and intermembrane exchange of lipid material between two populations of liposomes possessing individual thermodynamic characteristics.A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Fax 627071. Brigham Young University, Provo, Utah, USA. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 78–82, January–February, 1994.