嵌套病例对照研究中的两步估计方法（英）

本文讨论嵌套病例对照研究中相对危险率的估计问题，引入了相对危险率的两步估计，并在一般嵌套病例对照抽样的假设下讨论了相对危险率的两步估计的相合性问题，最后给出了几个例子。     

随机右删失下密度与危险率函数的估计及其收敛速度

本文根据定义的密度函数的估计式，得到了其一致收敛速度，并由此得到了危险率函数的强一致收敛速度．     

多类型复发事件间隔时间下可加危险率模型

在许多的生物医学和工程研究中,多类型复发事件的间隔时间数据是很常见的。众所周知,比例危险率模型在一些情况下不能很好拟合生存数据。本文,在多类型复发事件的间隔时间数据下,我们利用可加危险率模型来研究协变量对生存时间的影响程度。我们采用估计方程方法获得回归系数和基准累积危险率函数估计。并且,我们建立了所提估计的渐近分布。     

当前状态数据下单变点危险率治愈模型的拟极大似然估计

变点危险率模型已受到广泛关注.它不仅可以更加直接地显示治疗效果或医学上的突破,也可以提供这些事件发生的时间点.在这篇文章中,我们提出当前状态数据下的单边点危险率治愈模型并探讨了这个模型的估计方法.我们建立了估计的大样本理论并通过模拟评估有限样本下的估计.     

逐步增加Ⅱ型截尾下比例危险率模型的可靠性分析

基于逐步增加Ⅱ型截尾样本,分别在均方损失和Linex损失下,利用ML-Ⅱ方法研究了比例危险率模型的参数和可靠性指标的经验Bayes估计问题。为了研究估计结果的精确性,分析了一个实际应用例子,并利用Monte-Carlo方法给出一个数值模拟例子,结果表明在非对称Linex损失下,经验Bayes估计更具灵活性,且结果更加有效。     

09-0685(四次修改稿)_王亮 师义民 (逐步增加II型截尾下比例危险率模型的可靠性分析) 2010-03-05

基于逐步增加 II 型截尾样本，分别在均方损失和 Linex 损失下，利用 ML-II 方法研究了比例危险率模型的参数和可靠性指标的经验 Bayes 估计问题。为了研究估计结果的精确性，分析了一个实际应用例子，并利用 Monte-Carlo 方法给出一个数值模拟例子，结果表明在非对称 Linex 损失下，经验 Bayes 估计更具灵活性，且结果更加有效。     

Panel模型中两步估计的优良性

本文研究Panel模型中未知参数的估计问题，给出了两步估计的协方差的准确表达式．用均方误差作为度量估计的优劣标准，我们建立了两步估计优于Within估计和最小二乘估计的充要条件．特别我们获得了两步估计优于Within估计的简单充分条件．一般说来，对于中等数量的样本容量，两步估计就优于Within估计，类似的结论对Between估计或最小二乘估计也成立．     

相依线性回归系统的泛岭改进估计

对于一类相依线性回归系统，本文提出了一种泛岭改进估计，并讨论了这种估计及相应的两步估计的优良性质，获得了若干深入的结果．     

线性指数危险率模型的贝叶斯判别分析

设有两个总体Π0和Π1，其危险率为具有不同参数的线性函数。对于待观测的寿命样本X，给出了相应的判别分析问题的Bayes停止判决法则，其中损失函数包括试验费用和误判损失两部分。      

部分线性回归模型的M-估计

本文讨论部分线性回归模型的M-估计．用局部线性方法给出未知函数的M-估计，用两步估计方法给出参数的M-估计．进一步证明了未知函数的M-估计的弱一致性和渐近正态性，参数的M-估计的弱一致性．     

Nested case-control analysis with general additive-multiplicative hazard models

This paper discusses the nested case-control analysis under a class of general additive-multiplicative hazard models which includes the Cox model and the additive hazard model as special cases.A pseudo...     

Estimating hazard ratios in nested case-control studies by mantel-haenszel method

1. IntroductionConsider a follow-up study which is carried out to investigate the association betweenexposure variables and mortality rate in a cohort. In the case where the cohort is of 1argesise, the complete follow-up ndght be too expensive or difficult, and various nested samplingmethod8 have been suggested by Thomas[l], Prenti..[2] 5 Goldstein and Langholzl'] and otherauthors. Most of the authors employ Coxl4] regression mode1 for estimating the hazard ratio8of exposures.Now a well-reco…     

Adaptive sparse grid algorithms with applications to electromagnetic scattering under uncertainty

We discuss adaptive sparse grid algorithms for stochastic differential equations with a particular focus on applications to electromagnetic scattering by structures with holes of uncertain size, location, and quantity. Stochastic collocation (SC) methods are used in combination with an adaptive sparse grid approach based on nested Gauss-Patterson grids. As an error estimator we demonstrate how the nested structure allows an effective error estimation through Richardson extrapolation. This is shown to allow excellent error estimation and it also provides an efficient means by which to estimate the solution at the next level of the refinement. We introduce an adaptive approach for the computation of problems with discrete random variables and demonstrate its efficiency for scattering problems with a random number of holes. The results are compared with results based on Monte Carlo methods and with Stroud based integration, confirming the accuracy and efficiency of the proposed techniques.     

BVPs on infinite intervals: A test problem,a nonstandard finite difference scheme and a posteriori error estimator

As far as the numerical solution of boundary value problems defined on an infinite interval is concerned, in this paper, we present a test problem for which the exact solution is known. Then we study an a posteriori estimator for the global error of a nonstandard finite difference scheme previously introduced by the authors. In particular, we show how Richardson extrapolation can be used to improve the numerical solution using the order of accuracy and numerical solutions from 2 nested quasi‐uniform grids. We observe that if the grids are sufficiently fine, the Richardson error estimate gives an upper bound of the global error.     

A semiparametric Wald statistic for testing logistic regression models based on case-control data

We propose a semiparametric Wald statistic to test the validity of logistic regression models based on case-control data. The test statistic is constructed using a semiparametric ROC curve estimator and a nonparametric ROC curve estimator. The statistic has an asymptotic chisquared distribution and is an alternative to the Kolmogorov-Smirnov-type statistic proposed by Qin and Zhang in 1997, the chi-squared-type statistic proposed by Zhang in 1999 and the information matrix test statistic proposed by Zhang in 2001. The statistic is easy to compute in the sense that it requires none of the following methods: using a bootstrap method to find its critical values, partitioning the sample data or inverting a high-dimensional matrix. We present some results on simulation and on analysis of two real examples. Moreover, we discuss how to extend our statistic to a family of statistics and how to construct its Kolmogorov-Smirnov counterpart. This work was supported by the 11.5 Natural Scientific Plan (Grant No. 2006BAD09A04) and Nanjing University Start Fund (Grant No. 020822410110)     

Empirical bayesian test of the smoothness

In the context of adaptive nonparametric curve estimation a common assumption is that a function (signal) to estimate belongs to a nested family of functional classes. These classes are often parametrized by a quantity representing the smoothness of the signal. It has already been realized by many that the problem of estimating the smoothness is not sensible. What can then be inferred about the smoothness? The paper attempts to answer this question. We consider implications of our results to hypothesis testing about the smoothness and smoothness classification problem. The test statistic is based on the empirical Bayes approach, i.e., it is the marginalized maximum likelihood estimator of the smoothness parameter for an appropriate prior distribution on the unknown signal.     

Estimate of the Constant in Two Strengthened C.B.S. Inequalities for F.E.M. Systems of 2D Elasticity: Application to Multilevel Methods and a Posteriori Error Estimators

The constant γ in the strengthened Cauchy-Buniakowski-Schwarz (C.B.S.) inequality plays a crucial role in the convergence rate of multilevel iterative methods as well as in the efficiency of a posteriori error estimators, that is in the framework of finite element approximations of SPD problems. We consider the approximation of the 2D elasticity problem by the Courant element. Concerning multilevel convergence rate, that is the γ corresponding to nested general triangular meshes of size h and 2h, we have proved that γ²≤ 3/4$ uniformly on the mesh and the Poisson ratio. Concerning error estimator, that is the γ corresponding to quadratic and linear approximations on the same mesh, numerical computations have shown that the exact γ for a reference element deteriorates that is goes to one, when the Poisson ratio tends to 1/2     

Estimating Orthant Probabilities of High-Dimensional Gaussian Vectors with An Application to Set Estimation

The computation of Gaussian orthant probabilities has been extensively studied for low-dimensional vectors. Here, we focus on the high-dimensional case and we present a two-step procedure relying on both deterministic and stochastic techniques. The proposed estimator relies indeed on splitting the probability into a low-dimensional term and a remainder. While the low-dimensional probability can be estimated by fast and accurate quadrature, the remainder requires Monte Carlo sampling. We further refine the estimation by using a novel asymmetric nested Monte Carlo (anMC) algorithm for the remainder and we highlight cases where this approximation brings substantial efficiency gains. The proposed methods are compared against state-of-the-art techniques in a numerical study, which also calls attention to the advantages and drawbacks of the procedure. Finally, the proposed method is applied to derive conservative estimates of excursion sets of expensive to evaluate deterministic functions under a Gaussian random field prior, without requiring a Markov assumption. Supplementary material for this article is available online.     

Complexity penalized support estimation

We consider the estimation of the support of a probability density function with iid observations. The estimator to be considered is a minimizer of a complexity penalized excess mass criterion. We present a fast algorithm for the construction of the estimator. The estimator is able to estimate supports which consists of disconnected regions. We will prove that the estimator achieves minimax rates of convergence up to a logarithmic factor simultaneously over a scale of Hölder smoothness classes for the boundary of the support. The proof assumes a sharp boundary for the support.