Crystal Structure of Taxinine A

ＣｒｙｓｔａｌＳｔｒｕｃｔｕｒｅｏｆＴａｘｉｎｉｎｅＡＷＵＮａｎ；ＬＵＹａｎｇ；ＺＨＥＮＧＱｉ－Ｔａｉ；ＦＡＮＧＷｅｉ－Ｓｈｕｏ；ＴＯＮＧＸｉａｏ－Ｊｉｅ；ＦＡＮＧＱｉ－Ｃｈｅｎｇ（ＩｎｓｔｉｔｕｔｅｏｆＭａｔｅｒｉａＭｅｄｉｃａ，ＣｈｉｎｅｓｅＡｃ...     

The Site-Specific Hydrolysis of l-β-Hydroxybaccatin Ⅱ by Aspergillus Niger

ＴｈｅＳｉｔｅ－ＳｐｅｃｉｆｉｃＨｙｄｒｏｌｙｓｉｓｏｆｌ－β－ＨｙｄｒｏｘｙｂａｃｃａｔｉｎⅡｂｙＡｓｐｅｒｇｉｌｌｕｓＮｉｇｅｒ￥ＪｕｎＺｅｎｇＺＨＡＮＧ；ＬｉＨｅＺＨＡＮＧ（ＴｈｅＮａｔｉｏｎａｌＲｅｓｅａｒｃｈＬａｂｏｒａｔｏｒｉｅｓｏｆＮａ...     

The Responsivity of the Bacteriorhodopsin Langmuir－Blodgett Film Intermittent Light

ＴｈｅＲｅｓｐｏｎｓｉｖｉｔｙｏｆｔｈｅＢａｃｔｅｒｉｏｒｈｏｄｏｐｓｉｎＬａｎｇｍｕｉｒ－ＢｌｏｄｇｅｔｔＦｉｌｍＩｎｔｅｒｍｉｔｔｅｎｔＬｉｇｈｔ￥ＧｕａｎｇＹｕＷＡＮＧ；ＪｉａｎＨｕａＹＡＮＧ；ＺｈｉＧｕａｎｇＺＨＡＮＧ；ＳｈｕＨｕａｎｇＬＩＮ...     

Template Synthesis and Structure of Dinuclear Zinc Complex with Three Kinds of Pyrazole Ligands

ＴｅｍｐｌａｔｅＳｙｎｔｈｅｓｉｓａｎｄＳｔｒｕｃｔｕｒｅｏｆＤｉｎｕｃｌｅａｒＺｉｎｃＣｏｍｐｌｅｘｗｉｔｈＴｈｒｅｅＫｉｎｄｓｏｆＰｙｒａｚｏｌｅＬｉｇａｎｄｓＺＨＡＮＧＷｅｎ－Ｘｉｎｇ；ＭＡＣｈａｎｇ－Ｑｉｎ；ＷＡＮＧＸｕ－Ｎｉｎｇ；ＹＵＺｈｅ...     

Silica－supported Polysiloxane with Selenacrown Ether Moieties and Its Platinum Complex

Ｓｉｌｉｃａ－ｓｕｐｐｏｒｔｅｄＰｏｌｙｓｉｌｏｘａｎｅｗｉｔｈＳｅｌｅｎａｃｒｏｗｎＥｔｈｅｒＭｏｉｅｔｉｅｓａｎｄＩｔｓＰｌａｔｉｎｕｍＣｏｍｐｌｅｘＬＵＸｕｅ－ｒａｎ；ＺＨＡＮＧＬｉ－ｆｅｎｇ；ＷＡＮＧＺｈｅｎ－ｘｉａ；ＬＩＵＸｉｕ－ｆａｎｇａ...     

Crystal and Molecular Structure of Quinide

ＣｒｙｓｔａｌａｎｄＭｏｌｅｃｕｌａｒＳｔｒｕｃｔｕｒｅｏｆＱｕｉｎｉｄｅＷＡＮＧＧａｎｇ－Ｌｉ；ＺＨＡＯＳｈｕ－Ｊｉｅ；ＣＨＥＮＤｅ－Ｃｈａｎｇ（ＮａｔｉｏｎａｌＩｎｓｔｉｔｕｔｅｆｏｒｔｈｅＣｏｎｔｒｏｌｏｆＰｈａｒｍａｃｅｕｔｉｃａｌａｎｄＢｉ...     

Study on the Total Synthesis of Hainanolide－Construction of Tricyclic Intermediate（I）

ＳｔｕｄｙｏｎｔｈｅＴｏｔａｌＳｙｎｔｈｅｓｉｓｏｆＨａｉｎａｎｏｌｉｄｅ－ＣｏｎｓｔｒｕｃｔｉｏｎｏｆＴｒｉｃｙｃｌｉｃＩｎｔｅｒｍｅｄｉａｔｅ（Ｉ）ＬｕＹａｎＺＨＡＮＧ；ＳｈｉＺｈｉＣＨＥＮ；ＤｏｎｇＷＥＩ；ＬｉａｎｇＨＵＡＮＧ；ＪｉＪｉｅＣＨＡ...     

Studies on Artificial Imitation of Glutathione Peroxidase by Chemical Mutation

ＳｔｕｄｉｅｓｏｎＡｒｔｉｆｉｃｉａｌＩｍｉｔａｔｉｏｎｏｆＧｌｕｔａｔｈｉｏｎｅＰｅｒｏｘｉｄａｓｅｂｙＣｈｅｍｉｃａｌＭｕｔａｔｉｏｎＤＩＮＧＬａｎ；ＺＨＵＺｈｅｎ－ｑｉ；ＬＵＯＧｕｉ－ｍｉｎ；ＳＵＮＱｉ－ａｎ；ＹＡＮＧＴｏｎｇ－ｓｈｕａｎｄＳＨ...     

An AM1 Study on the Mechanism of Uridine Phospborolysis

ＡｎＡＭ１ＳｔｕｄｙｏｎｔｈｅＭｅｃｈａｎｉｓｍｏｆＵｒｉｄｉｎｅＰｈｏｓｐｂｏｒｏｌｙｓｉｓＳｈａｎＲｏｎｇＺＨＡＯ；ＱｉｎＭｉＷＡＮＧ；ＫａｉＸｉａｎＣＨＥＮ；Ｓｕｏ－ＢａｏＲＯＮＧ，Ｒｕ－ＹｕｎＪＩ（ＳｈａｎｇｈａｉＩｎｓｔｉｔｕｔｅｏｆＭａｔ...     

Synthesis of 1,3-cyclic Monoalkyl(acyl)-racglycerothiophosphates of Uridine

Ｓｙｎｔｈｅｓｉｓｏｆ１，３－ｃｙｃｌｉｃＭｏｎｏａｌｋｙｌ（ａｃｙｌ）－ｒａｃｇｌｙｃｅｒｏｔｈｉｏｐｈｏｓｐｈａｔｅｓｏｆＵｒｉｄｉｎｅＣｈｅｎｇＸｉａｎｇＺＨＡＮＧ；ＲｕＹｕＣＨＥＮ；ＣｈｕＣｈｉＴＡＮＧ；ＨｕａｎＭｉｎｇＣＨＥＮ（Ｒｅｓｅａｒ...     

关于7种含氧酸结构与酸性的讨论

含氧酸是无机化学授课的一个重要内容，讨论了含氧酸中亚硫酸、硼酸、次磷酸、亚磷酸、溴酸、亚溴酸、碳酸的结构与酸性。研究表明，SO2溶液中存在着2种异构体；硼酸在不同条件下存在Lewis酸和Brönsted酸2种形式；次磷酸、亚磷酸、溴酸、亚溴酸都存在着异构化倾向；在一定条件下，碳酸具有一定的动力学稳定性。     

Synthesis and identification of dinitro- and diaminoterephthalic acid

Dinitroterephthalic acid(DNTPA) and diaminoterephthalic acid(DATPA) were prepared in 85%and 75%yields,respectively. These compounds were characterized by using FTIR and ~1HNMR.DATPA can be used as a monomer for the preparation of polyesters and polyamides.     

几种糖醛酸及其寡糖的薄层层析分析

以葡萄糖醛酸（GlcA）、半乳糖醛酸（GalA）、甘露糖醛酸（ManA）、古罗糖醛酸（GulA）、半乳糖醛酸寡糖（Oligo-GalA）、甘露糖醛酸寡糖（Oligo-ManA）、古罗糖醛酸寡糖（Oligo-GulA）和酶解褐藻胶寡糖（Oligo-u-Alg）为研究对象,探讨其薄层色谱（TLC）行为。结果表明,TLC对不同糖醛酸寡糖有良好的分离和分析效果,其中Oligo-GalA与褐藻胶来源的寡糖兄值不同,而同样来源于褐藻胶的Oligo-ManA与Oligo-GulAR,值相同;首次发现酸解与酶解褐藻胶寡糖聚合度相同时兄值不同。此外,4种糖醛酸对不同的显色剂的显色灵敏度也略有不同,其中硫酸铈显色剂的显色效果最灵敏。这些结果为快速有效分析酸性寡糖的纯度及其聚合度,提供了简便有效的方法。     

离子色谱法测定威力酸中的有机酸

采用离子排斥分离,电导检测模式,对威力酸中的4种有机酸成份进行分离测定。将威力酸样品通过萃取、洗涤、过滤之后进样,可以测定其柠檬酸、乳酸、苹果酸、富马酸4种有机酸,在一定的色谱条件下,4种阴离子都具有很好的线性和较低的检出限。威力酸中的柠檬酸,乳酸,苹果酸,富马酸的检出限分别是0.10、0.14、0.30和0.12μg/L,线性相关系数r2在0.9997~0.9999范围内,样品中待测离子峰面积的RSD在4.3%以下(n=10),回收率在94%~105%之间。采用抑制电导的离子色谱法是分析威力酸中的有机酸成份的高效与准确的方法。     

固体过氧钼酸的制备及其性质研究

本文提供了制备固体过氧钼酸的新方法,它以Na_2MoO_4为原料,按Mo:H_2O_2=2.00:1.05(摩尔比)和游离酸度为0.40mole/dm~3的量加入H_2O_2和HNO_3,然后在50℃条件下加热20小时,析出Mo:(O_2):H_2O=2:1:2的固体过氧钼酸,得率96%。用热分析和超高真空程序升温质谱研究了它的性质,并推断其可能结构。     

离子色谱法测定水中4种有机酸

建立了水样中甲酸、乙酸、丙烯酸和甲基丙烯酸的离子色谱测定方法,采用IonPac AS11-HC阴离子分离柱,以KOH为淋洗液,采用浓度梯度洗脱,可同时测定上述4种有机酸。方法对实际水样中甲酸、乙酸、丙烯酸和甲基丙烯酸的平均加标回收率在80.2%~103.3%,相对标准偏差在5.8%之内,检出限分别为:0.005,0.003,0.005和0.004mg/L;定量下限分别为:0.020,0.012,0.020和0.016mg/L。方法准确、简便、环保,能够满足实际水样的测定需要,且水样中常见的阴离子不会对目标污染物的测定产生影响。     

Mitocanic Di- and Triterpenoid Rhodamine B Conjugates

The combination of the “correct” triterpenoid, the “correct” spacer and rhodamine B (RhoB) seems to be decisive for the ability of the conjugate to accumulate in mitochondria. So far, several triterpenoid rhodamine B conjugates have been prepared and screened for their cytotoxic activity. To obtain cytotoxic compounds with EC₅₀ values in a low nano-molar range combined with good tumor/non-tumor selectivity, the Rho B unit has to be attached via an amine spacer to the terpenoid skeleton. To avoid spirolactamization, secondary amines have to be used. First results indicate that a homopiperazinyl spacer is superior to a piperazinyl spacer. Hybrids derived from maslinic acid or tormentic acid are superior to those from oleanolic, ursolic, glycyrrhetinic or euscaphic acid. Thus, a tormentic acid-derived RhoB conjugate 32, holding a homopiperazinyl spacer can be regarded, at present, as the most promising candidate for further biological studies.     

12-钼磷酸的Brnsted酸位和Lewis酸位

研究了加热、抽空等预处理对固态12-钼磷酸(PMA)酸位的影响。发现了PMA上除存在B-酸位外,还可生成L-酸位。研究了PMA上L-酸位的成因,水在两类酸位形成过程中的作用,L-酸位与B-酸位的相对强度,以及PMA上酸强度的分布。据此,对Miscno等认为PMA中只存在质子酸和酸强度分布均匀的观点提出了不同的看法。