共查询到20条相似文献,搜索用时 15 毫秒
1.
Kaigorodova Elena А. Gantsgorn Natal’ya M. Konyushkin Leonid D. Krapivin Gennady D. 《Chemistry of Heterocyclic Compounds》2019,55(11):1098-1103
Chemistry of Heterocyclic Compounds - Alkylation of 6-methyl-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one in an alkaline medium proceeds regioselectively at the sulfur atom to form sulfanyl... 相似文献
2.
Klyuchko S. V. Chumachenko S. A. Shablykin O. V. Brovarets V. S. 《Russian Journal of General Chemistry》2021,91(3):348-356
Russian Journal of General Chemistry - A method for the synthesis of a series of new substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones was proposed based on the Diels–Alder type reaction... 相似文献
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G. A. Gazieva N. G. Kolotyrkina A. N. Kravchenko N. N. Makhova 《Russian Chemical Bulletin》2014,63(2):431-434
Diastereoselective [3+2] cycloaddition of azomethine ylide to 1,3-dimethyl-6-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-3a,9a-diphenyl-3,3a,9,9a-tetrahydroimidazo[4,5-e]thiazolo[3,2-b]-[1,2,4]triazine-2,7(1H,6H)-dione yields hitherto unknown 1,1′,3-trimethyl-3a,9a-diphenyl-3,3a,9,9a-tetrahydrodispiro(imidazo[4,5-e]thiazolo[3,2-b][1,2,4]triazine-6,3′-pyrrolidine-4′,3″-indole)-2,2″,7(1H,1″H)-triones. 相似文献
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SOLIMAN Ahmed Youssef ATTIA Ibrahim Abd El-Mogoud SALEM Moneer Abdu Ibrahim SOLIMAN El-SayedAhmed GABER Adel Mohy El-Deen 《中国化学》1996,14(5):437-446
Science Department, Faculty of Teachers, P.O.Box 2313, Al Hasa, 31982, Saudi Arabia Faculty of Engineering, Ain Shames University, EgyptChemistry Department, Faculty of Science, Ain Shames University, Egypt 相似文献
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Tsizorik Nazar M. Hrynyshyn Yevhenii V. Bol’but Andriy V. Vovk Mykhailo V. 《Chemistry of Heterocyclic Compounds》2018,54(11):1075-1078
Chemistry of Heterocyclic Compounds - 4-Chloropyrazolo[1,5-a]pyrazines react with ethyl isocyanoacetate to form ethyl imidazo[1,5-a]pyrazolo[5,1-c]pyrazine-1-carboxylates, hydrolysis of which... 相似文献
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It has been found that some acyl derivatives of 1,2,3,4-tetrahydro-1-indolizin-1-one 1and (1H)-3,4-dihydropyrrolo[1,2-a]pyrazin-1-one 2 show remarkable anti-inflammatory and analgesic activities1,2. The interest in extending the study of structure-activity relationships and search of new potent anti-inflammatory and analgesic agents led us to design and synthesize (1H)-3,4-dihydropyrrolo[2,1-c][1,4]oxazin-1-one 3 derivatives. NO 1 NNHO2 87654321ONO3 A few examples of the p… 相似文献
8.
The title compound (C18H15FN6OS) has been synthesized and its crystal structure was determined by X-ray analysis. The crystal belongs to monoclinic system, space group P21/n with a = 13.983(10), b = 7.337(5), c = 16.702(12) (A), α = 90, β = 98.277(12), γ = 90°, V = 1696(2)(A)3, Z = 4, Dc= 1.498 g/cm3, Mr = 382.42,μ = 0.224 mm-1, F(000) = 792, the final R = 0.0362 and wR = 0.0878 for 2579 observed reflections with I > 2σ(Ⅰ). In the title compound, the atoms of C(1),C(2), C(3), C(4), C(5), N(1), N(2), N(3), N(4), N(5), N(6), O(1) and S(1) form a fully delocalized system with the average deviation of 0.0307(A). There exists a part of electron delocalization over the planes of Ⅰ (pyrazolo[3,4-d]pyrimidin-4-one moiety), Ⅱ (phenyl moiety) and Ⅲ (p-fluorophenylamine moiety). In the molecule, intermolecular hydrogen bonds between N(6)-H(6)…O(1)and C( 15)-H( 15)…O( 1 ) are observed. 相似文献
9.
Ivanov S. M. Mironovich L. M. Rodinovskaya L. A. Shestopalov A. M. 《Russian Chemical Bulletin》2017,66(6):1126-1130
Russian Chemical Bulletin - New pyrido[2′,3′:3,4]pyrazolo[5,1-c][1,2,4]triazin-4(6H)-one derivatives were synthesized from accessible 1,2,4-triazine and pyrazolo[5,1-c][1,2,4]triazine... 相似文献
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Unprecedented cyclization was observed during N-sulfonylation of 3-[1-(phenylhydrazono)-ethyl]-chromen-2-one in pyridine, affording 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones. To avoid use of noxious pyridine, reaction was tried in different basic conditions and the best results were obtained with potassium carbonate in acetone. A wide range of substrates bearing either electron-donating or electron-withdrawing substituents on phenylhydrazine ring were compatible with the developed methodology. Rapid access of starting material, 3-acetylcoumarin, excellent yields of products, and use of environmentally benign base and solvent for the cyclization make this strategy an efficient and convenient method for synthesis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones. 相似文献
11.
《高等学校化学研究》1991,(2)
In recent years, fused heterocycles have been reported to possess important properties in synthesis and pharmacology. Especially, s-triazolo, 3,4-thiadiazole derivatives have been attracting much attention for chemists and pharmacologists because they show broad spectra of biological activities, such as antifungal, antibacterial, hy- 相似文献
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Topuzyan V. O. Hovhannisyan A. A. Tosunyan S. R. Tamazyan R. A. Ayvazyan A. G. Makichyan A. T. 《Russian Journal of General Chemistry》2022,92(9):1610-1620
Russian Journal of General Chemistry - A method for the synthesis of 1-dialkylaminoalkyl-2-phenyl-4-arylidene-5-imidazolones from N-benzoyl-α,β-dehydroamino acid dialkylaminoalkylamides... 相似文献
13.
A facile, efficient, and environmentally benign procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones via the cyclocondensation reaction of aromatic aldehyde, ethyl acetoaceate, and urea catalyzed by CsF–Celite was developed. This environmentally friendly method is superior to previous methods with respect to reaction time, yield, and workup. 相似文献
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Russian Journal of Organic Chemistry - The condensation of 7-amino-1-benzyl-3-tert-butyl-4-oxo-1,4-dihydropyrazolo[5,1-c][1,2,4]triazine-8-carbonitrile with formic acid afforded... 相似文献
16.
Guo Qiang HU* Song Qiang XIE Wen Long HUANG Hui Bin ZHANG Medicinal College of Henan University Kaifeng China Pharmaceutical University Nanjing 《中国化学快报》2005,(6)
1,2,4-Triazole derivatives, such as 1, 2, 4-triazolo[3, 4-b]thiadiazoles and 1, 2, 4- triazolo [3,4-b]thiadiazolines, as potent antibacterial agents have been widely investigated1-4. Chemically, their structures mainly focus on bi-fused heterocycles, but tri-fused derivatives have not been reported. In continuing our previous works5-8 on finding better antibacterial agents, we herein reported the synthesis and pharmacological evaluation for completely new class of compounds 4a~e with antibacte… 相似文献
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Russian Journal of General Chemistry - Some novel (E)-2-cyano-3-(substituted phenyl/dimethylamino)-N′-[1-(pyren-3-yl)]acrylohydrazides and benzochromenone-2-carbohydrazide derivatives were... 相似文献
18.
(S)-(+)-4-Amino-4-aryl-5,5,5-trifluoropentan-2-ones reacted with 6h-chlorobenzyl isocyanates with formation of (S)-(+)-4-aryl-6-(2-arylethenyl)-4-trifluoromethyl-3,4-dihydropyrimidin-2(1H)-ones. 相似文献
19.
John Nicolson Low Justo Cobo Manuel Nogueras Adolfo Sánchez Jairo Quiroga Diana Mejía 《Acta Crystallographica. Section C, Structural Chemistry》2001,57(11):1356-1358
Molecules of the title compound, C28H27ClN4O4·C2H6O, form a C(6) chain via an N—H⋯O hydrogen bond along the c axis by the operation of a c-glide plane, with N⋯O = 2.761 (3) Å and N—H⋯O = 165°. The molecules are further linked by a weak C—H⋯O interaction, with C⋯O = 3.344 (4) Å and C—H⋯O = 150°. Pendant hydrogen-bonded ethanol solvent molecules are attached to the chains by O—H⋯N hydrogen bonds, with O⋯N = 2.904 (3) Å and O—H⋯N = 175°. 相似文献
20.
《Tetrahedron letters》1987,28(10):1073-1076
The general problem of the synthesis of 3,6-dideoxy sugars containing stereospecifically labeled hydrogen isotope at C-3 is addressed for the specific case of ascarylose (3,6-dideoxy-L-arabino-hexose). 相似文献