共查询到20条相似文献,搜索用时 15 毫秒
1.
L. M. Mironovich 《Chemistry of Heterocyclic Compounds》1998,34(5):617-619
Azomethines, derivatives of 4-amino-1,2,4-triazines, have been obtained by the reaction of 4-nitroso-3-thioxo-6-R-1,2,4-triazin-5(2H)-ones with acetylacetone and ethyl acetoacetate.Sumy State University, Sumy 244007, Ukraine. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 698–700, May, 1998. 相似文献
2.
Boiling of ethyl cyanoacetate with 6-tert-butyl-3-hydrazino-1'2'4-triazin-5(2H)-one in alkalinemedium yielded 6-tert-butyl-3-(5-hydroxy-3-oxo-2'3-dihydro-1H-pyrazol-1-yl)-1'2'4-triazin-5(2H)-one.Acylation of 6-tert-butyl-3-hydrazino-1'2'4-triazin-5(2H)-one with benzoyl chloride furnished 3-benzoyl-hydrazido-1'2'4-triazine that cyclized when treated with POCl3 providing a derivative of[1'2'4]triazolo[4'3-b][1'2'4]triazine. Boiling of 6-tert-butyl-3-hydrazino-1'2'4-triazin-5(2H)-one in glacialacetic acid gave rise to diacetylated derivative whereas the boiling with acetic anhydride in an inert solventafforded monoacetylated product. 相似文献
3.
Yuzuru Sanemitsu Yoshinori Nakayama Masato Mizutani Kazuyuki Oshie 《Journal of heterocyclic chemistry》1984,21(3):639-641
Reduction of 3-methylthio-1,2,4-triazin-5(4H)-one ( 1a ) with sodium borohydride afforded 3-methylthio-1,6-dihydrotriazin-5(4H)-one ( 2b ) selectively. 3-Methylthio-6-t-butyl-1,2,4-triazin-5(4H)-one ( 1d ) reacted with sodium borohydride to give mainly 6-t-butyl-2,3-dihydro-1,2,4-triazin-5(4H)-one ( 3d ). The reaction of various 4-methyl-1,2,4-triazin-5(4H)-ones with sodium borohydride and the influence of bulkiness and electronic effect of the substituents at the 3- and 6-positions upon the product ratio, are also discussed. 相似文献
4.
Egorov IN Tseitler TA Kovalev IS Slepukhin PA Rusinov VL Chupakhin ON 《The Journal of organic chemistry》2012,77(14):6007-6013
Reactions between substituted 1,2,4-triazines and ketones were investigated. General procedures for one-pot synthesis of hydrogenated derivatives of such polycyclic systems as benzo[c][1,2,4]triazino[1,6-a][2]azecine, [1,2,4]triazino[1,6-f]phenantridine, and dicyclopenta[b,d]pyrido[1,2-f][1,2,4]triazine are described. 相似文献
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Treatment of methyl α-(dimethylarninomethyleneamino)carboxylates 1 (from α-amino acids and dimethylformamide dimethylacetal) with hydrazine gives 5-substituted-4,5-dihydro-1,2,4-triazin-6-ones 2 , which are smoothly dehydrogenated to 5-substituted-1,2,4-triazin-6-ones 3 with potassium permanganate in acetone/acetic acid. 相似文献
6.
Beresnev D. G. Rusinov G. L. Ponomareva A. Yu. Chupakhin O. N. 《Russian Chemical Bulletin》2003,52(10):2161-2166
Recyclization of the addition products of alkylureas to 3-aryl-1,2,4-triazin-5(2H)-ones affording 1,2,4-triazole derivatives was found to occur in Ac2O. 相似文献
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The reaction of 6-(tert-butyl)-3-hydrazino-1,2,4-triazin-5(2H)-one with acetone and benzaldehyde yields the corresponding hydrazones. In the presence of thionyl chloride the benzaldehyde hydrazone is converted to 3-(tert-butyl)-6-phenyl-1,2,4-triazolo[4,3-b]-1,2,4-triazin-2(1H)-one and this can also be formed via the acylation of the starting hydrazinotriazinone using benzoyl chloride. 相似文献
8.
Beresnev DG Itsikson NA Chupakhin ON Charushin VN Kodess MI Butakov AI Rusinov GL Morzherin YY Konovalov AI Antipin IS 《The Journal of organic chemistry》2006,71(21):8272-8275
A convenient way to modify calix[4]arenes based on the direct C-C coupling reaction of their phenol moiety with 1,2,4-triazines has been advanced, and the ability of modified calixarenes to provide transport of La3+ and Ga3+ cations through organic membranes has been examined. 相似文献
9.
The reaction of various α-silyl-α-keto esters with thiosemicarbazide at 50 °C in ethyl acetate was found to give α-silyl-substituted thiosemicarbazone-acetic acid esters in good yield. These may then be converted to their corresponding silyl-substituted 1,2,4-triazin-5-ones by cyclization under basic conditions. 相似文献
10.
Masato Mizutani Yuzuru Sanemitsu Yoshinao Tamaru Zen-Ichi Yoshida 《Tetrahedron》1985,41(22):5289-5293
The S → N allylic transposition of 4-allylthiopyrimidin-2(lH)-ones 4 and 5-allylthio-1,2,4-triazin-3(2H)-ones 5 has been performed successfully by catalysis of palladium(II) salts. In both cases the N-alkylated products (6 and 7) are obtained with no traces of the C-alkylated products. 相似文献
11.
Masato Mizutani Yuzuru Sanemitsu Yoshinao Tamaru Zen-ichi Yoshida 《Tetrahedron letters》1985,26(9):1237-1240
Selective transformation of 3-propargylthio-1,2,4-triazin-5(2H)-ones () to 6-methylene-6,7-dihydro-4H-thiazolo[2,3-c][1,2,4]-triazin-4-ones () and 3-methylene-2,3-dihydro-7H-thiazolo[3,2-b]-[1,2,4]triazin-7-ones () is performed under the conditions of Pd(II) salt or sodium hydroxide catalysis, respectively. 相似文献
12.
The IR spectra of a number of fused 1,2,4-triazin-5-ones have been studied and the relevance of the results to triazinone tautomerism is discussed. 相似文献
13.
Vladimir L. Rusinov Grigori V. Zyryanov Tatjana L. Pilicheva Oleg N. Chupakhin Hans Neunhoeffer 《Journal of heterocyclic chemistry》1997,34(3):1013-1019
3-Aryl-1,2,4-triazin-5(2H)-ones 1a-c react with indoles 2a-c in trifluoroacetic acid/chloroform or in boiling butanol or acetic acid to give 3-aryl-6-(indolyl-3)-1,6-dihydro-1,2,4-triazin-5(2H)-ones 3a-g . Oxidation of the dihydro-1,2,4-triazin-5(2H)-ones 3a-e afforded 6-(indolyl-3)-1,2,4-triazin-5(2H)-ones 4a-e , products of nucleophilic substitution of hydrogen in 1a-c . Refluxing 1b with N-methylpyrrote 5b in butanol for an extended time resulted in the formation of 3-(4-chlorophenyl)-6-(1-meuiylpyrrolyl-2)-1,2,4-triazin-5(2H)-one 4h. The reaction of 1a-c with indoles 2a-c , pyrroles 5a,b , 1,3-dimethyl-2-phenylpyrazol-4-one (8) and aminothiazoles 9a,b in acetic anhydride affords the 1-acetyl-3-aryl-6-hetaryl-1,6-dihydro-1,2,4-triazin-5(2H)-ones 6a-s . Reaction of 1a-c with N-methyl-pyrrole 5b in acetic anhydride gives beside the 1:1 addition products 6h-k also the 2:1 addition products 7a-c . 相似文献
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15.
Yuzuru Sanemitsu Yoshinori Nakayama Masao Shiroshita 《Journal of heterocyclic chemistry》1982,19(6):1583-1584
A regioselective synthesis of 2-amino-1,2,4-triazinones ( 3a-b ) is reported, by reaction of 3-methylthio-1,2,4-triazinones ( 1a-b ) with O-(2,4-dinitrophenyl)hydroxylamine ( 2 ), as an amino transfer agent. A spectroscopic study and an unequivocal synthesis of 2-amino-4-methyl-6-phenyl-1,2,4-triazinone ( 8a ) has shown the site of amination to be N2 of the 1,2,4,-triazinone ring. Subsequent reaction of 2-amino-1,2,4-triazinone ( 3b ) with ammonium hydroxide, followed by ring closure with formic acid provided [1,2,4]triazolo[2,3-b][1,2,4]triazin-7 (1H)-one ( 10 ). 相似文献
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Lszl Ürgdi Lajos Kisfaludy gnes Patthy Ern Moravcsik Helga Tüds Zsuzsanna Tegyei Lszl
tvs 《Journal of heterocyclic chemistry》1989,26(1):129-132
The title compounds 4 were synthesized via the acid-catalyzed reaction of α-(acylaminooxy)carboxylic acid amides 6 with carbonyl compounds, and controlled catalytic hydrogenation of the resulting 2-benzyloxy-carbonyldihydro-2H-1,2,4-oxadiazin-5(6H)-ones 7 (R6 = PhCH2O). 相似文献
20.
《Tetrahedron letters》1982,23(24):2499-2500
The oxidation of 4-amino-1,2,4-triazine herbicides (1) with t-butylhydroperoxide catalyzed by Co(Salen) resulted in the specific deamination of the 4-amino group, providing a chemical model for the metabolism of the herbicides. 相似文献