Tannin and Related Compounds from Terminalia catappa and Terminalia parviflora

Continuing chemical examination on tannins and related compounds of Combretaceous plants has led to the isolation of one novel complex type tannin, catappanin A, together with two phenolcarboxylic acids, two phenol glucoside gallates, seven ellagic tannins, one other hydrolyzable tannin, four flavan-3-ols and two complex type tannins from the bark of Terminalia catappa. In addition, from the bark of Terminalia parviflora one new methyl glucoside gallate, methyl 3,6-di-O-galloyl-β-D-glucoside, three phenolcarboxylic acids, three gallotannins, six ellagitannins and three other hydrolyzable tannins were isolated. Their structures were elucidated on the basis of chemical and spectroscopic evidence.     

Combretins A and B,New Cycloartane‐Type Triterpenes from Combretum fragrans

The phytochemical studies on the leaves of the traditionally used medicinal plant Combretum fragrans F. Hoffm (Combretaceae) from Cameroon have led to the isolation of combretins A and B ( 1 and 2 , resp.), two new cycloartane‐type triterpenes from the AcOEt‐soluble subfraction along with β‐sitosterol ( 3 ), oleanolic acid ( 4 ), ursolic acid ( 5 ), and pratensein ( 6 ). The compounds 4  –  6 are reported for the first time from this species. The structures of the new triterpenes were elucidated by spectroscopic techniques including ¹H‐ and ¹³C‐NMR (DEPT), and 2D‐NMR experiments.     

Two New‐Skeleton Compounds from Sarcandra glabra

Two new‐skeleton compounds, sarcaboside A ( 1 ) together with its artifact sarcaboside B ( 2 ), were isolated from the whole plant of Sarcandra glabra. Their structures were elucidated on the basis of extensive spectroscopic analysis as well as HR‐ESI‐MSⁿ study.     

Neolignans from the Parasitic Plants. Part 1. Aeginetia Indica

Two new neolignans, namely balanophonin 4‐O‐β‐d ‐glucopyranoside and aegineoside together with four known neolignans have been isolated from the whole plant of Aeginetia indica Linn. (Orobanchaceae). Their structures were established by spectroscopic and chemical methods.     

Reactive Organometallic Compounds Obtained from Metallocenes and Related Compounds and Their Synthetic Applications

Progress in the synthesis of organometallic compounds via the partial or total degradation of metallocenes and related compounds under mild reaction conditions is reviewed. These degradation reactions permit highly reactive organo-transition metal complexes to be prepared which can in turn be used in a wide range of synthetic reactions. Examples include catalytic reactions such as the cobalt-catalyzed hydrogenation of benzene and the manganese-catalyzed cyclotrimerization of butadiene as well as stoichiometric syntheses of mono- and polynuclear transition metal complexes, some of which have novel structural features.     

Biflavonoids,Lignans, and Related Compounds from the Roots of Diplomorpha canescens

Two new biflavonoids, 14″‐O‐methyldihydrodaphnodorin B ( 1 ) and 14″‐O‐methyldaphnodorin J ( 2 ), along with 16 known compounds, i.e., dihydrodaphnodorin B ( 3 ), daphnodorin J ( 4 ), 3″‐epidihydrodaphnodorin B ( 5 ), daphnodorin B ( 6 ), neochamaejasmin B ( 7 ), sikokianin B ( 8 ), (?)‐syringaresinol ( 9 ), (?)‐syringaresinol 4‐O‐β‐D ‐glucopyranoside ( 10 ), (+)‐nortrachelogenin ( 11 ), (?)‐lariciresinol ( 12 ), (?)‐pinoresinol ( 13 ), syringin ( 14 ), syringinoside ( 15 ), daphnoretin ( 16 ), phorbol 13‐acetate ( 17 ), and methyl paraben ( 18 ) were isolated from the roots of Diplomorpha canescens (Meisn.) C.A. Meyer . The structures were determined on the basis of spectroscopic data.     

保幼激素类似物ZR－512的简便合成及其对印度大头蚁（PheidoleindicaMayr）的有效性

本文报导了ＺＲ－５１２的简便合成方法，总收率为４９％，并发现ＺＲ－５１２对印度大头蚁ＰｈｅｉｄｏｌｅｉｎｄｉｃａＭａｙｒ具有极显著的活性。     

涩感物质及涩感转导机制

涩感物质是影响食品及饮料风味品质的重要因素,由于涩感物质具有抗菌、抗癌、抗氧化、保护神经等作用,近年来成为人们研究的热点。通常涩感被描述为多酚等物质作用于口腔后产生的一种干燥、粗糙、褶皱和收敛的感觉,人们对涩感究竟是味觉,是触觉还是类似于辣感的三叉神经觉的争论一直存在。大多数关于涩感产生机制的研究都以蛋白质聚集沉淀的理论模型为基础。本文将对一些产生涩感的物质及涩感转导机制进行介绍。     

Synthesis of Ecdysteroids and Related Compounds

Literature data published in 1998-2002 on the chemical synthesis of ecdysteroids and their structural analogs were reviewed.     

An Ethylenedioxy Flavonoid Carboxylic Acid from Limnophila Indica

The hexane extract of the aerial parts and roots of Limnophila indica yielded a new flavone, 3′,4′‐ethylenedioxy‐5‐hydroxy‐3‐(1‐hydroxy‐1‐methylethyl)‐6,7‐dimethyl‐5′‐methoxyflavone‐8‐carboxylic acid ( 1 ), characterized by spectral studies.     

Two New Compounds from Rhododendron Przewalskii Maxim

Two new ionone derivatives, rhododendrone A and rhododendronside, have been isolated from the alco-holic extract of the aerial parts of Rhododendron Przewalskii Maxim. The structures of the two compounds, (3R, 6S)-3-hydroxy-a-ionone 1 and 1,1,5-trimethyl-6-(3-hydroxyl)cyclohexene-5-yl-1-β-D-pyranoglucoside 2, have been elucidated on the basis of the spectroscopic analyses.     

Diterpenoid and Phenolic Compounds from Juncus effusus L.

A novel diterpene, named effusenone A ( 1a ), which is the first reported rosane‐type diterpene from a Juncaceae plant, and three novel phenolic compounds, 5‐(hydroxymethyl)‐1‐methylphenanthrene‐2,7‐diol ( 4 ), 1‐methylpyrene‐2,7‐diol ( 5 ), and 7‐methoxy‐8‐methylpyren‐2‐ol ( 6 ) were isolated from the stem of Juncus effusus L. by normal‐phase and reversed‐phase silica gel column chromatography. Their structures were identified by spectroscopic methods, especially 2D‐NMR techniques.     

Bioactive Compounds of the Flora of Belarus. 4. Pterosins A and B from Pteridium aquilinum

Sesquiterpenoids pterosins A (1) and B (2) and the flavonol glycoside astragalin were isolated from the aerial part of the bracken-fern Pteridium aquilinum.     

A new cytotoxic biflavonoid from the rhizome of Wikstroemia indica

One new chalcone-flavone biflavonoid, 3′-hydroxydaphnodorin A (1), together with 12 known biflavonoids (2–13), was isolated from the rhizome of Wikstroemia indica. Their structures were established on the basis of extensive spectroscopic methods. Eight isolated compounds 1–3, 6, 7, 9, 12 and 13 were evaluated for their cytotoxic activities against cancer-derived cell lines Hep3B, HepG2 and CNE2, and 1 was found to possess moderate cytotoxicity against HepG2 and CNE2 cell lines, with IC₅₀ values of 65.5 ± 11.4 and 53.6 ± 10.1 μM, respectively.     

Determination of Melting Points for A2B6 Compounds

A new technique of rapid heating, recording both the melting and evaporation processes in an open system was proposed to determine the melting points of A2B6 (A=Zn, Cd) compounds. The different melting character and temperatures were detected for the equiatomic and non-stoichiometric composition of A2B6. A fit of these data to previously obtained results was considered and the reasons for their discrepancy were discussed. This revised version was published online in July 2006 with corrections to the Cover Date.     

Benzazetidines and Related Compounds: Synthesis and Potential

Benzazetidines are a class of N-heterocycles potentially very interesting for a variety of purposes, including biological applications and drug design. In the past, their high ring strain has hampered the development of trustable, general, and efficient synthetic methodologies for their preparation. In this review article, the aim is to disclose all the literature contributions about the synthesis of these compounds and the study of their reactivity, from the early examples to the most recent synthetic approaches. Recently, there has been a growth of interest for this heterocycle, driven by the publication of novel synthetic methodologies based on palladium-catalyzed intramolecular C−H amination and organocatalyzed ring-closure of 2-(N-Boc-anilino)-α-ketoesters/amides.     

甘西鼠尾草中三个新的萜类化合物

采用反复硅胶、葡聚糖凝胶、反相硅胶及MCI凝胶柱色谱等多种色谱方法分离纯化了甘西鼠尾草的化学成分,根据理化性质和波谱数据对化合物的结构进行了鉴定.由甘西鼠尾草的根和根茎的50%乙醇提取物中得到了2个新的二萜化合物,命名为甘西鼠尾三醇A(1)和甘西鼠尾三醇B(2),同时得到了一个新的单萜苷化合物,命名为甘西鼠尾甲苷(3)...     

Nickel-Catalysed Reactions of Allyl Halides and Related Compounds

Allyl compounds react with carbon monoxide, or with carbon monoxide and acetylene, in the presence of tetracarbonylnickel as catalyst. These catalysts are involved also in coupling reactions and addition reactions of activated olefins and ketones. Reactions of this type can be used for the preparation of unsaturated aliphatic acids, esters, nitriles, hydrocarbons, alicyclic ketones, keto acids, keto esters, diketones, lactones, phenols, and other compounds. The reactions proceed via π-allylnickel complexes.     

Tris(benzophenoneimino)phosphane and Related Compounds

A new group of bases with benzophenoneiminyl (bpi) moiety has been synthesized and characterized in this work. The title compound tris(benzophenoneimino)phosphane (P(bpi)₃) 1 was prepared with a convenient one-pot approach: benzophenone imine was deprotonated using MeMgCl and reacted with PBr₃ in diglyme. The method could be considered as a method of choice for preparing other (amino)phosphanes in case lithio-intermediates and/or protonated phosphane is out of consideration. Phosphane 1 is further used to prepare a range of related phosphonium cations and phosphazenes. Phosphonium cations were deprotonated to assess the stability of the resulting phosphonium ylides. In some cases, the bulky substances were capable of forming P−N heterocycles. Experimental (MeCN) and computational (MeCN, THF, gas-phase) basicities of benzophenone imine, phosphane 1 , phosphonium ylides, and phosphazenes, as well as some representative XRD structures, are presented and discussed.