[2+2] Cycloaddition of benzyne to cis,trans- and cis,cis-1,5-cyclooctadiene

The relative rates of formation of $\text{cis}$ and $\text{trans}$ [2+2]cycloadducts of benzyne to $\text{cis}$, $\text{trans}$- and $\text{cis}$, $\text{cis}$-1,5-cyclooctadiene, $\text{trans}$- and $\text{cis}$-cyclooctene are discussed and properties of the adducts (e.g., their unusual hydrogenation) are described.     

Methods for stereospecific synthesis of cis or trans hydrindanones

Methods are described for the stereospecific conversion of hydrindenone 3 either to the corresponding $\text{trans}$ fused or $\text{cis}$ fused hydrindanone (1 or 2, respectively.)     

Singlet oxygenation of cis,cis-1,5-cyclooctadiene: a convenient synthetic entry into 5,8-difunctionalized oxygen derivatives of 1,3-cyclooctadiene

The 6-hydroperoxy-1,4-cyclooctadiene ($\text{2}$), which is formed in the photosensitized oxygenation of 1,5-cyclooctadiene ($\text{1}$), affords on further singlet oxygenation 5,8-dihydroperoxy-1,3-cyclooctadiene ($\text{3}$), which via triphenylphosphine reduction leads to $\text{cis}$-5,8-dihydroxy-1,3-cyclooctadiene ($\text{4}$) and subsequent pyridinium chlorochromate oxidation to 1,3-cyclooctadien-5,8-dione ($\text{8}$).     

Stereocontrolled (E,Z and erythro, threo) synthesis of ⊙-hydroxyallylic sulphides

All four isomers of substituted 3-alkylthio-4-hydroxybutenes have been synthesised: both the geometry of the double bond and the relative stereochemistry of the two chiral centres are controlled.     

Olefin metathesis in polycyclic frames 1. A new way to cis, syn, cis - tricyclopentanoids (acs-C11-triquinanes)

A novel olefin metathesis sequence permits ready access to functionalised $\text{cis}$, $\text{syn}$, $\text{cis}$-tricyclo [6.3.0.0^2,6] undecane based bis-enones. These bis-enones have been shown to undergo cage cyclisation in sunlight with remarkable ease and efficiency.     

cis Δ5-octahydro-1-naphtalenones and cis Δ5-decahydro-1-naphthalenes (cis-1-decalones) by stereoselective intramolecular diels-alder reaction.

Intramolecular DIELS-ALDER reactions of requisite trienes led to $\text{cis}$-1-decalones, $\text{via}$ an endo intermediate state.     

A general method for cis-hydroisoquinoline synthesis

A method is described which allows for the conversion of N-carbomethoxy-1,2-dihydropyridine to cis-hydroisoquinolines via a Diels-Alder/Cope rearrangement sequence.