共查询到20条相似文献,搜索用时 31 毫秒
1.
We have developed an efficient method for the synthesis of 2,5-dihydrofuran and 2,5-dihydropyrrole skeletons from the simply modified Baylis-Hillman adducts via RCM reaction. 相似文献
2.
Mi Jung Lee 《Tetrahedron letters》2006,47(11):1833-1837
3-Benzylidenecyclohexene derivatives were prepared starting from the Baylis-Hillman adducts by using DBU-promoted domino process involving Michael, aldol, dehydration, and dealkoxycarbonylation. 相似文献
3.
Seong Jin Kim 《Tetrahedron letters》2007,48(6):1069-1072
3,5,6-Trisubstituted α-pyrones were synthesized starting from the Baylis-Hillman adducts. The synthesis was carried out via the sequential introduction of ketone at the primary position of Baylis-Hillman adduct, lactonization, and the following oxidation with PCC. 相似文献
4.
Syntheses of 2-amino-2,3-dihydrobenzofuran derivatives 3a-g and fully substituted furans 5a-f were achieved starting from the Baylis-Hillman adducts. We prepared 2-amino-2,3-dihydrobenzofurans from the Baylis-Hillman adducts of methyl and ethyl acrylates and fully substituted furans from the Baylis-Hillman adducts of alkyl vinyl ketones. 相似文献
5.
Facile synthetic method of polysubstituted pyridine derivatives was developed starting from the Baylis-Hillman adducts. The reaction involved sequential introduction of tosylamide, Michael addition, aldol condensation, elimination of p-toluenesulfinic acid, and isomerization process. 相似文献
6.
A versatile protocol for the production of sugar-linked alpha,beta-unsaturated gamma-lactones with stereochemical and functional group diversity is described starting from sugar-derived Baylis-Hillman adducts via ring-closing metathesis. 相似文献
7.
Hyun Seung Lee 《Tetrahedron letters》2009,50(19):2274-9061
An expedient method was developed for the synthesis of 1,4,5,6-tetrahydropyridines by radical cyclization protocol involving consecutive 1,5-hydrogen transfer and double bond isomerization process starting from Baylis-Hillman adducts. 相似文献
8.
Seung Chan Kim 《Tetrahedron》2008,64(1):103-109
Poly-substituted benzenes were synthesized in moderate yields starting from the Baylis-Hillman adducts. The synthesis was carried out by two steps via first synthesis of cyclohexene intermediates and the following DBU-assisted unusual dehydrogenation. 相似文献
9.
Polysubstituted phenol derivatives were synthesized regioselectively starting from the Baylis-Hillman adducts via the formal [4+2] annulation protocol as the key step. 相似文献
10.
Ka Young Lee 《Tetrahedron letters》2005,46(32):5387-5391
Facile synthetic method of 2H-indazole derivatives was developed involving DDQ oxidation of pyrazoles, which were prepared starting from the Baylis-Hillman adducts of 2-cyclohexen-1-one. 相似文献
11.
Sung Hwan Kim 《Tetrahedron letters》2009,50(15):1696-3242
We developed an efficient synthetic method of diallylated δ-valerolactam and γ-butyrolactam derivatives via an indium-mediated successive double Barbier type allylations starting from the Baylis-Hillman adducts. 相似文献
12.
Ko Hoon Kim 《Tetrahedron letters》2010,51(26):3368-40
A facile synthesis of benzofulvene derivatives was carried out starting from the Baylis-Hillman adducts of 2-bromobenzaldehyde via the sequential bromination, In-mediated Barbier reaction with aldehyde, acetylation, Pd-catalyzed intramolecular Heck reaction, and the elimination of AcOH. 相似文献
13.
Hyun Seung Lee 《Tetrahedron》2008,64(10):2397-2404
N-Tosyl-3,3-disubstituted-4-vinylpyrrolidine derivatives 3a-c were synthesized via radical cyclization from the modified Baylis-Hillman adducts 2. The required starting materials 2a-c were prepared in moderate yields from the Baylis-Hillman adducts in three steps: (i) acetylation of the Baylis-Hillman adducts, (ii) SN2′ reaction with tosylamide to prepare 1, and (iii) alkylation with 1,4-dibromo-2-butene. 相似文献
14.
Saravanan Gowrisankar 《Tetrahedron letters》2008,49(10):1670-1673
We synthesized 2-arylquinolines and tetrahydropyridines via palladium-mediated Heck type reactions starting from the Baylis-Hillman adducts. 2-Arylquinolines were prepared via the Heck type cyclization followed by concomitant aerobic oxidation. 相似文献
15.
Eun Sun Kim 《Tetrahedron letters》2009,50(36):5098-1390
An efficient synthetic protocol of fully substituted α-pyrones has been developed starting from the Baylis-Hillman adducts. Subsequent Diels-Alder reaction of the α-pyrones and DMAD produced poly-substituted aromatic compounds in high yields. 相似文献
16.
Saravanan Gowrisankar 《Tetrahedron》2006,62(17):4052-4058
Construction of furo[3,4-c]pyran ring skeleton was achieved starting from the Baylis-Hillman adducts. The synthesis was carried out by the successive introduction of propargyl alcohol, radical cyclization, reduction, allylation, and finally ring-closing metathesis reaction. 相似文献
17.
Seung Chan Kim 《Tetrahedron letters》2006,47(20):3463-3466
We prepared some 3-aryl-3-hydroxypyrrolidin-2-ones and tricyclic 2-benzyl-9b-hydroxy-3,3a,5,9b-tetrahydro-2H-pyrrolo[3,4-c]quinoline-1,4-diones starting from the Baylis-Hillman adducts of isatin derivatives. 相似文献
18.
Ko Hoon Kim 《Tetrahedron letters》2009,50(11):1249-3518
3,4-Disubstituted 2(1H)-quinolinones were synthesized starting from the Baylis-Hillman adducts via the following sequential processes: (i) hydrolysis of the Baylis-Hillman adduct to acid, (ii) EDC coupling with anilines, (iii) H2SO4-assisted intramolecular Friedel-Crafts cyclization, and the final (iv) DBU-mediated isomerization. 相似文献
19.
Serendipitous synthesis of 2-amino-2,3-dihydrobenzofuran derivatives 4a-g was achieved starting from the Baylis-Hillman adducts. In the reaction sequence, intramolecular oxygen atom transfer from nitrogen atom to arene moiety was observed. 相似文献
20.
Da Yeon Park 《Tetrahedron letters》2006,47(37):6641-6645
Polysubstituted benzene derivatives were synthesized starting from the Baylis-Hillman adducts via the sequential introduction of primary nitroalkane at the primary position, Michael addition to β-branched Michael acceptor, aldol condensation, elimination of nitrous acid, and the final aromatization process. 相似文献