共查询到20条相似文献,搜索用时 15 毫秒
1.
Morphologicaldeformationsofthemyceliaorconidiaofmicroorganismssuchascurling,swelling,hyper-divergence,beadformationandinhibitionofgermination,areofteninducedinthepresenceofbioactivesubstances".AnewscreeningbioassaymethodfordetectingthedeformationofmyceliagerminatedfromconidiaofPyriculartaoryzaeP-2bwasfirstdevelopedforthequantitativeapplicationtoscreeningantifungalandantineoplasticagentsbyH.Kobayashi'.Thisbioassayisquick,easytoperform,andhasbeenefficientlyusedinthepreliminaryscreeningofantineo… 相似文献
2.
A New Furostanol Saponin from Dioscorea futshauensis 总被引:1,自引:0,他引:1
A new furostanol saponin presenting moderate bioacitivity of inducting morphological deformation of Pyricularia oryzae mycelia was isolated from Dioscorea futshauensis R.Kunth by bioacitivity-guided fractionation. The structure was established as 26-O-β-D-glucopyranosyl-3β,26-diol-23(S)-methoxyl-(25R)-furost-5,20(22)-diene-3-O-[α-L-rhamnopyranosyl(1→2)-β-D-glucopyranosyl(1→3)]-β-D-glucopyranoside on the basis of chemical evidencesand spectral analysis,especially by 2D-NMR techniques. 相似文献
3.
A New Spirostanol Saponin from Dioscorea futshauensis 总被引:1,自引:0,他引:1
Hong Wei LIU Hisayoshi KOBAYASHI Ge Xia QU Xin Sheng YAO* Department of Natural Products Chemistry Shenyang Pharmaceutical University Shenyang Institute of Molecular & Cellular Biosciences The University of Tokyo Tokyo Japan 《中国化学快报》2001,(7)
A new screening bioassay detecting deformation of mycelia germinated from conidia of Pyricularia oryzae P-2b was first developed for quantitative application to screen antifungal and antineoplastic agents by H. Kobayashi1,2. We have introduced and applied this bioassay in the search of bioactive agents from Traditional Chinese Medicine3,4. The ethanol extract of Dioscorea futshauensis R. Kunth (Dioscoreaceae) showed a strong activity against the growth of Pyricularia oryzae P-2b. Its buta… 相似文献
4.
AnLIU ZhongMeiZOU LiZhenXU ShiLinYANG 《中国化学快报》2003,14(11):1144-1145
A new compound, subglain B, was isolated from the stems of Uvaria tonkinensis var.subglabra and its structure was identified as 1S, 2R, 3S, 6R-1-benzoyloxymethylene-1,2-dihydroxy-3-benzoyloxy-6-chlorocyclohex-4-ene (1), by spectral evidences. 相似文献
5.
防己叶菝葜为百合科菝葜属植物(SmilaxmenispermoidesD.C.),分布在我国西北,西南地区,民间用于祛风除湿代替中药土伏苓(S.ChinaRaxb)[1,2]。迄今未见其化学成分的报道,本文报道防己叶菝葜中一个新的甾体皂甙1的结构鉴定。 相似文献
6.
Three New Diarylpropanes from Dioscorea composita 总被引:1,自引:0,他引:1
ShunLiYANG XiKuiLIU 《中国化学快报》2005,16(1):57-60
Three new diarylpropanes were isolated from the dried rhizomes of Dioscorea composita Hemsl., and their structures were determined as 1, 3-bis-(2-hydroxy-4-methoxyphenyl) propane (1), 1, 3-bis-(2, 4-dihydroxyphenyl)propane (2), 1-(2′-hydroxy-4′-O-β-D- glucopymnosy-phenyl)-3-(2“, 4“-dihydroxyphenyl)propane (3), by spectroscopic analysis, respectively. 相似文献
7.
Hong Wei LIU Xin Sheng YAO Nai Li WANG Guo Ping CAI 《中国化学快报》2006,17(2):211-214
The Aesculus genus consists of about thirty species distributed in Asia, Europe andAmerica. There are sixteen species distributed in China, and most of them are used asherbal medicines for the treatment of distention and pain in the chest and abdomen. Anu… 相似文献
8.
One new triterpenoid saponin,monepaloside K(1) was isolated from the water-soluble part of the whole plant of a famous Tibetan medicinal herb,morina neplaensis var. alba Hand.-Mazz.Its structure was determined to be 3-O-α-L-arabinopyranosyl-(1→3)-β-D-xylopyranosyl siaresinolic acid on the basis of spectroscopic evidences,especially 2D NMR techniques. 相似文献
9.
GuoYingZUO HongPingHE BinGuiWANG XinHONG YiMingHU XiaoJiangHAO 《中国化学快报》2003,14(4):383-384
A new diterpenoid,15-0-accetylspiraminol(1),was isolated from the aerial parts of Spireae japonica L.f.var.ovalifolia.The structure was charaterized mainly based on spectral analysis. 相似文献
10.
Rémy Bertrand Teponno Azefack Léon Tapondjou Hyun Ju‐Jung Jung‐Hwan Nam Pierre Tane Hee‐Juhn Park 《Helvetica chimica acta》2007,90(8):1599-1605
From the bulbils of Dioscorea bulbifera L. var. sativa, three new clerodane diterpenoids, bafoudiosbulbin C (=methyl (2β,8α,12S)‐17‐oxo‐2,19 : 8,19 : 12,17 : 15,16‐tetraepoxycleroda‐3,13(16), 14‐triene‐18‐carboxylate; 1 ), bafoudiosbulbin D (=methyl (2β,6β,12R)‐17,19‐dioxo‐2,19 : 6,17 : 8,12 : 15,16‐tetraepoxycleroda‐13(16),14‐diene‐18‐carboxylate; 2 ), and bafoudiosbulbin E (=methyl (2β,3α,4α,6β,12R)‐17,19‐dioxo‐2,19 : 3,4 : 6,17 : 8,12 : 15,16‐pentaepoxycleroda‐13(16),14‐diene‐18‐carboxylate; 3 ) were isolated, together with the known compounds bafoudiosbulbins A and B, 3‐O‐β‐D ‐glucopyranosyl‐β‐sitosterol, and 6′‐stearoyl‐3‐O‐β‐D ‐glucopyranosyl‐β‐sitosterol. Their structures were established by high‐field NMR techniques (1H,1H‐COSY, 13C‐DEPT, HSQC, HMBC, and NOESY), MS analyses, as well as by comparison of their spectral data with those of related compounds. 相似文献
11.
AiHuaZHAO ShengHongLI YongWeiLi QuanBinHUAN QinShiZHAO ZhongWenLIN HanDongSUN 《中国化学快报》2003,14(6):591-593
The structures of two new abietane quinones,named micranthins A and B,were determined to be 7α-methoxy-14,16-epoxy-8,13-abietabiene-11,12-dione(1) and 16-acetoxy-6,7-dehydroroyleanone (2) respectively,which were isolated from Isodon lophanthoides var.micranthus. 相似文献
12.
Yanjun Sun Ruyi Pan Haojie Chen Chen Zhao Ruijie Han Meng Li Guimin Xue Hui Chen Kun Du Junmin Wang Weisheng Feng 《Molecules (Basel, Switzerland)》2022,27(4)
Three new polyhydroxylated oleanane triterpenoids, cissatriterpenoid A−C (1−3), along with one known analogue (4), were isolated from the whole plant of Cissampelos pareira var. hirsuta. Their chemical structures were elucidated by extensive spectroscopic data (IR, HR-ESI-MS, 1H-NMR, 13C-NMR, DEPT, 1H-1H COSY, HSQC, HMBC, NOESY) and the microhydrolysis method. The isolation of compounds 1–4 represents the first report of polyhydroxylated oleanane triterpenoids from the family Menispermaceae. All isolated compounds were evaluated for their cytotoxicity against five human cancer cell lines, and the inhibitory activity against NO release in LPS-induced RAW 264.7 cells. Compound 3 showed the most potent cytotoxic activities against the A549, SMMC-7721, MCF-7, and SW480 cell lines, with IC50 values of 17.55, 34.74, 19.77, and 30.39 μM, respectively, whereas three remaining ones were found to be inactive. The preliminary structure–activity relationship analysis indicated that the γ-lactone ring at C-22 and C-29, and the olefinic bond at C-12 and C-13 were structurally required for the cytotoxicity of polyhydroxylated oleanane triterpenoids against these four cell lines. Based on lipid-water partition coefficients, compound 3 is less lipophilic than 1 and 4, which agrees with their cytotoxic activities. This confirms the potential of C. pareira var. hirsuta in the tumor treatment. 相似文献
13.
云南重楼中的新甾体皂苷 总被引:3,自引:0,他引:3
从云南重楼Paris polyphylla Sm. var. yunnanensis(France. )Hand.-Mazz.的干燥根茎中分离鉴定了4个甾体皂苷(1~4), 其中化合物1是新化合物, 采用波谱技术鉴定其结构为24-O-β-D-吡喃半乳糖基-(23S,24S)-螺甾-5, 25(27)-二烯-1β,3β,23,24-四醇-1-O-β-D-吡喃木糖基(1→6)-β-D-吡喃葡萄糖基(1→3)[α-L-吡喃鼠李糖基(1→2)]-β-D-吡喃葡萄糖苷. 相似文献
14.
15.
Chen‐Yang Li Hao Gao Wei‐Hua Jiao Long Zhang Guang‐Xiong Zhou Xin‐Sheng Yao 《Helvetica chimica acta》2010,93(3):450-456
Three new diterpenoids, together with three known ones, were isolated from the air‐dried whole herbs of Rabdosia lophanthoides var. gerardiana. The structures of the new diterpenoids were established as 3,4‐dihydro‐11‐hydroxy‐10‐(1‐hydroxy‐1‐methylethyl)‐2,2,6‐trimethylnaphtho[1,8‐bc]oxocin‐5(2H)‐one ( 1 ), 11,12,15‐trihydroxyabieta‐5,8,11,13‐tetraen‐7‐one ( 2 ), (2R,3S,4S,4aR,8S,9aS,13aS,16aS)‐3,4,4a,8,9,9a,10,11,12,13,14,16a‐dodecahydro‐2‐(hydroxymethyl)‐6,6,10,10‐tetramethyl‐2H‐benzo[4,5]cyclohepta[1,2‐h]pyrano[2,3‐b][1,4]benzodioxepine‐3,4,8,13a,15(6H)‐pentol ( 3 ) by spectroscopic methods, including extensive 1D‐ and 2D‐NMR analyses. The structures of the known compounds were identified by comparison of their physical and spectroscopic data with those reported in the literature. 相似文献
16.
Hong Ping HE Yue Mao SHEN Xiao Sheng YANG Bin Gui WANG Ling LI Xiao Jiang HAO * Laboratory of Phytochemistry Kunming Institute of Botany the Chinese Academy of Sciences Kunming . The Key Laboratory of Chemistry for Natural Prod 《中国化学快报》2001,(1)
Spiraea japonica L. (Rosaceae) is widely distributed in Yunnan Provence, P. R. China. Previous chemical investigations on S. japonica and its varieties have led to the report of 7 new atisane-type diterpenoids and 38 new diterpene alkaloids of atisine- and hetisine-type1-11. This paper describes the isolation and structure elucidation of two new diterpene alkaloids named spiratines A and B (1-2). Their structures were elucidated on the basis of 1D and 2D NMR experiments (HMQC, HMBC, 1… 相似文献
17.
New Diterpenoid Alkaloids from Spiraea japonica var. Ovalifolia 总被引:2,自引:0,他引:2
Guo Ying ZUO Hong Ping HE Xin HONG Wei Ming ZHU Yi Ming HU Xiao Sheng YANG Xiao Jiang HAO* Laboratory of Phytochemistry Kunming Institute of Botany Chinese Academy of Sciences Kunming Kunming Hospital PLA Kunming 《中国化学快报》2001,(2)
In the investigation of the chemical constituents of Spireae japonica L. f. var. ovalifolia (Rosaceae), a shrub originated in Songming, Yunnan, five new diterpenoid alkaloids, 19-O-deethylspiramine N (1), deacetylspiramine S (2), spiramidine A (3), spiramidine B (4) and deacetylspiramine F (5), were isolated from aerial parts of the plant and structurally elucidated. Compound 1, a white amorphous powder with [(]+17.99 (c, 0.26, MeOH ), was determined to have the molecular formula of C20H… 相似文献
18.
Rita C. Almeida‐Lafet Marcelo J. P. Ferreira Vicente P. Emerenciano Maria A. C. Kaplan 《Helvetica chimica acta》2010,93(12):2478-2487
In the first phytochemical study of the Aureliana genus (Solanaceae), two new withanolides, 1 and 2 , together with two known sterols, were isolated from the MeOH extract of the leaves of Aureliana fasciculata var. fasciculata. The structures were established as (4S,22R)‐16α‐acetoxy‐5β,6β‐epoxy‐4β,17α‐dihydroxy‐1‐oxowitha‐2,24‐dienolide (aurelianolide A) and (4S,22R)‐16α‐acetoxy‐4β,17α‐dihydroxy‐1‐oxowitha‐2,5,24‐trienolide (aurelianolide B). The new compounds possessed the unusual 16α,17α‐dioxygenated group and were fully characterized by spectroscopic techniques, including 1H‐ and 13C‐NMR (DEPT), as well as 2D‐NMR (HMBC, HMQC, 1H,1H‐COSY, NOESY) experiments, and HR‐MS. 相似文献
19.
HaiYangLIU ChangXiangCHEN 《中国化学快报》2002,13(7):633-636
Two new C27 steroidal glycosides, named taccaoside A(1) and B(2), were isolated from the traditional Chinese herb Tacca plantaginea. The spectroscopic and chemical evidences revealed their structures to be 26-O-β-D-glucopyranosyl-(25R)-3β,26-dihydroxy furost-5,20-diene-3-O-[α-L-rhamnopyranosyl(1→2)]-[α-L-rhamnopyranosyl(1→3)]-β-D-glucopyranoside(1) and 26-O-β-D-glucopyranosyl-(25R)-3β,26-dihydroxy furost-5,20-diene-3-O-[α-L-rhamnopyranosyl-(1→2)]-[β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl(1→3)]-β-D-glucopyranoside(2),respectively. 相似文献