共查询到20条相似文献,搜索用时 15 毫秒
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Alexander S. Kiselyov Lucjan Strekowski Victor V. Semenov 《Journal of heterocyclic chemistry》1993,30(2):329-332
The title compounds 5 are produced in the reaction of N-fluoropyridinium tetrafluoroborate ( 1 ) with sulfides 2 . The proposed mechanism involves single-electron transfer from 2 to 1 followed by transformations of the resultant radical intermediates. 相似文献
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Tukaram S. Choudhare Devendra S. Wagare Vijay T. Kadam Prashant D. Netankar 《Journal of heterocyclic chemistry》2021,58(8):1637-1644
The present investigation describe the synthesis of 8-(benzyloxy)-5-(2-[1,3-diphenyl-1H-pyrazol-4-yl]thiazol-4-yl)quinolin-2(1H)-one derivatives. Quinolin-8-ol was transformed by five step synthetic procedures into 8-Benzyloxy-5-(2-bromo-acetyl)-1H-quinolin-2-one. Subsequently, 8-Benzyloxy-5-(2-bromo-acetyl)-1H-quinolin-2-one condensed with 1,3-Diphenyl-1H-pyrazole-4-carbothioic acid amide in the presence of acetonitrile to afford 8-(benzyloxy)-5-(2-[1,3-diphenyl-1H-pyrazol-4-yl]thiazol-4-yl)quinolin-2(1H)-one derivatives. Synthesized compounds were screened for their antimicrobial activity against gram-positive and gram-negative bacteria. Most of the synthesized compounds are found to be active against tested bacterial strains and fungal strain. 相似文献
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V. A. Kovtunenko T. T. Kucherenko R. I. Zubatyuk O. V. Shishkin D. A. Yushchenko 《Chemistry of Heterocyclic Compounds》2007,43(10):1301-1306
A method has been developed for the reaction of 2-cyanomethylbenzoic acid with N-methylanthranilic acid to give 2-[(1-methyl-4-oxo-1,4-dihydro-2-quinazolin-2-yl)methyl]benzoic
acid, its esters were synthesized. The spectroscopic chracteristics of the isomeric compounds have been studied and compared
in solution and in the solid state.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1532–1538, October, 2007. 相似文献
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Herein, synthesis of a series of naphtho[2,3-f]quinolin-13-one and naphtho[2,3-a]acridin-1(2H)-one derivatives directly by one-pot multi-component reaction of 1,3-dicarbonyl compounds (1,3-indanedione/1,3-cyclohexanedione), 2-aminoantharacene/2-naphthylamine and various substituted aldehydes under solvent-free conditions using heteropoly-11-molybdo-1-vanadophosphoric acid supported on montmorillonite K-10 clay catalyst (10% PVMoK-10) is reported. The successful formation of naphtho[2,3-f]quinolin-13-one and naphtho[2,3-a]acridin-1(2H)-one derivatives was confirmed by various spectroscopic techniques. This study offers a green approach for the synthesis of novel quinolinone derivatives. 相似文献
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Gabriela A. Rodrigo Sergio G. Renou Diana G. Bekerman M. Ins Abasolo Beatriz M. Fernndez 《Journal of heterocyclic chemistry》1997,34(2):505-508
Some novel 3-substituted benzoquinoxalinones [R = H, CH3, C6H5, (CH2)2COOH] were synthesized by the Hinsberg reaction between 2,3-diaminonaphthalene and several α-dicarbonyl compounds. The course of the reactions was followed by the second uv/visible Derivative Spectroscopy Method at different pH values (-0.89 to 9.0) and also in organic solvents at 25°. The compound non-substituted at C-3 was the only one that could be obtained in every media in good yields (80%), having pseudo first-order anelation rate constants of relative high values (1 × 10?1 — 1 × 10?2 min?1). On the other hand, only methanol could be used as the organic solvent for the synthesis of all of the other compounds; aqueous media always provided better results. In the 3-methyl derivative, as well as in the 3-phenyl derivative the change of the reaction pH medium modified the stoichiometry of the anelation, turning a non-quantitative reaction into a quantitative one. This is explained by a change in the mechanism of the reaction on going to lower hydrogen concentrations, a fact that was supported by complementary quantitative hptlc experiments. In general, pseudo first-order rate constants for the anelation were one or two logarithmic units lower than those of the non-substituted compound (RC-3 = H), but yields were above 60% in every case. A reaction scheme is presented which includes a probable mechanism. 相似文献
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The tributyltin radical-induced cyclization of N-(2-bromophenyl)-Nbutyl-1H-1-methylimidazole-4-carbox-amide 3 gave 5-butyl-3-methyl-3H-imidazo[4,5-c]quinolin-4(5H)-one 5 via [1,2]-acyl rearrangement. 相似文献
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YU Chen-Xia ZHU Xiao-Tong YAO Chang-Sheng TU Shu-Jiang 《结构化学》2007,26(5):533-536
The title compound (C16H14BrNO) has been synthesized by the reaction of p-tolylamine, Meldrum’s acid and 4-bromo-benzaldehyde, and its structure was characterized by IR, 1H NMR and X-ray single-crystal diffraction. The crystal belongs to monoclinic, space group P21/n with a = 7.6850(11), b = 8.3004(11), c = 21.301(3) , β = 95.110(2)°, V = 1353.4(3) 3, Mr = 316.19, Z = 4, Dc = 1.552 g/cm3, μ(MoKα) = 3.028 mm-1, F(000) = 640, the final R = 0.0345 and wR = 0.0768. X-ray analysis reveals that the atoms of C(1), C(2), C(3), C(4), C(5) and N(1) form a six-membered ring of boat conformation. 相似文献
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A mild, efficient, and environmentally benign one-pot synthesis of functionalized chromeno[4,3-b]pyrrol-4(1H)-ones by a three-component domino reaction of 4-aminocoumarins, arylglyoxal monohydrates, and 1,3-dicarbonyl compounds in refluxing ethanol without the use of catalyst is reported. The present protocol features operational simplicity, short reaction time, good yields, and the absence of aqueous workup procedure and chromatographic separation. 相似文献