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1.
D. A. Lomov 《Russian Journal of Organic Chemistry》2016,52(1):51-53
Treatment of 5-amino-1,3-dialkyl-2,3-dihydro-1H-imidazo[4,5-b]pyridin-2-ones with sodium nitrite in aqueous HCl gave 1,3-dialkyl-1H-imidazo[4,5-b]pyridine-2,5(3H,4H)-diones which were nitrated with potassium nitrate in sulfuric acid to 6-nitro derivatives, and the latter underwent recyclization into 4-amino-1,3-dialkyl-5-(1H-pyrazol-5-yl)-2,3-dihydro-1H-imidazol-2-ones by the action of hydrazine hydrate. 相似文献
2.
V. E. Semenov A. E. Nikolaev E. S. Krylova D. R. Sharafutdinova V. S. Reznik 《Russian Journal of Organic Chemistry》2012,48(4):582-587
Reactions of 1-(ω-bromoalkyl)-3,6-dimethyluracils and 1,3-bis(ω-bromoalkyl)-6-methyluracils with sodium azide gave the corresponding mono- and bis-azides. 1,3-Dipolar cycloaddition of the
latter with prop-2-yn-1-ol, hex-1-yne, and dec-1-yne in the presence of copper(I) ions afforded acyclic and macrocyclic uracil
derivatives containing 1,4-disubstituted 1,2,3-triazole fragments, which were subjected to quaternization with propyl iodide
and methyl p-toluenesulfonate at the 1,2,3-triazole nitrogen atom. 相似文献
3.
A reaction of N-allyl-substituted aminomethylene-1,1-bisphosphonates with aromatic nitrile N-oxides was used to obtain new aminomethylenebisphosphonates with one or two 3-arylisoxazoline rings at the nitrogen atom. NMR spectroscopy studies showed that the bisphosphonates with two isoxazoline fragments in the molecule exist in solution as a mixture of two diastereomers. 相似文献
4.
A. S. Shestakov O. E. Sidorenko I. S. Bushmarinov Kh. S. Shikhaliev M. Yu. Antipin 《Russian Journal of Organic Chemistry》2009,45(11):1691-1696
Two-stage reaction of methyl anthranilate with aryl(alkyl) isocyanates in keeping with the quantumchemical calculations and
XRD analysis resulted in 3-aryl(alkyl)quinazoline-2,4(1H,3H)-diones that by treatment with alkyl halides, phenacyl bromides, esters and amides of chloroacetic acid were converted into
the corresponding 1-alkyl derivatives. 相似文献
5.
《Comptes Rendus Chimie》2014,17(2):171-178
A variety of 4′-(4-R-phenyl)-4-(methylthio)-2′-phenyl-2′H-spiro[chromene-2,5′-[1,2,3]thiadiazole] 5a–d and 5′-(4-R-phenyl)-4-(methylthio)-3′-phenyl-3′H-spiro[chromene-2,2′-[1,3,4]thiadiazole] 6a–d were synthesized regioselectively through the reaction of 4-(methylthio)-2H-chromene-2-thione 2 with diarylnitrilimines under refluxing dry chloroform. Whilst the reaction of 4-(allylthio)-2H-chromene-2-thione 3 with diarylnitrilimines under similar reaction conditions afforded the corresponding 4-(allylthio)-5′-(4-R-phenyl)-3′-phenyl-3′H-spiro[chromene-2,2′-[1,3,4]thiadiazole] 7a–d and 5-(4-R-phenyl)-2′-methyl-3-phenyl-2′,3′-dihydro-3H-spiro[[1,3,4]thiadiazole-2,4′-thieno[3,2-c]chromene] 9a–d as two unisolable diastereoisomeric forms. The structures of the obtained spiro cycloadduct thiadiazoles have been assigned by means of spectroscopic measurements. 相似文献
6.
The condensation reaction of isomeric N-substituted (1H-pyrazol-4-yl)ethanones with the ethyl esters of pyrazole carboxylic acids and fluoroacetic acids has been studied using NaH
as the base. Under optimized conditions, it proved to be a convenient and preparative method for the synthesis of N-substituted
(1H-pyrazolyl)propane-1,3-diones and (1H-pyrazolyl)-4-polyfluorobutane-1,3-diones. 相似文献
7.
8.
M. S. Gruzdev U. V. Chervonova E. A. Venediktov E. P. Rozhkova A. M. Kolker E. A. Mazaev N. A. Dudina N. E. Domracheva 《Russian Journal of General Chemistry》2015,85(6):1431-1439
Method of synthesis has been developed for a series of 3,6-di-tert-butyl-9H-carbazole derivatives and their photochemical properties have been investigated. The dependence of the Steglich esterification reaction on the nature of the catalyst was studied. The synthesized compounds show fluorescent emission in the range 400–600 nm with a high quantum yield. 相似文献
9.
G. R. Berezina Yu. G. Vorob’ev S. M. Vorob’eva I. A. Andreikina 《Russian Journal of General Chemistry》2004,74(8):1254-1258
Symmetrical macroheterocyclic compounds are synthesized by the reaction of 1H-phenalene-1,3(2H)-diimine with m-phenylenediamine, 2,6-diaminopyridine, and 2,5-diamino-1,3,4-thiadiazole. IR and UV spectral data are given.Translated from Zhurnal Obshchei Khimii, Vol. 74, No. 8, 2004, pp. 1355–1359.Original Russian Text Copyright © 2004 by Berezina, Vorobev, Vorobeva, Andreikina.This revised version was published online in April 2005 with a corrected cover date. 相似文献
10.
The first cyclic unsaturated S-functional derivatives of 4,4-diphenyl-3,4-dihydro-2H-1,4-thiasiline, S-oxide, S,S-dioxide, and S-sulfonimide, were prepared. Oxidation of the hydrolytically less stable 4,4-dimethyl-3,4-dihydro-2H-1,4-thiasiline leads to the corresponding sulfoxide and sulfone along with the ring opening products, siloxanes containing the sulfoxide or sulfonyl group. 相似文献
11.
O. Yu. Slabko N. V. Ageenko V. A. Denisenko V. A. Kaminskii 《Russian Journal of Organic Chemistry》2017,53(2):231-235
Reactions of diazomethane with quinone mono(di)imines and methylidene quinone imines of pyrido[1,2-a]benzimidazole series occurs by the route of 1,3-dipolar cycloaddition and leads to the formation of quinoid compounds, in particular, previously unknown heterocyclic structures of indazolo[7',6':4,5]imidazo-[2,1-j]quinoline, indazolo[7',6':4,5]imidazo[2,1-e]acridine, indazolo[4',5':4,5]imidazo[2,1-j]quinoline, and indazolo[4',5':4,5]imidazo[2,1-e]acridine. 相似文献
12.
Yu. V. Shklyaev V. P. Feshin Yu. V. Nifontov 《Russian Journal of Organic Chemistry》2009,45(2):270-272
By the Hartree-Fock method in the basis 6–31G(d) with complete geometry optimization the charge value on the carbon atom of carbenium ion was shown to be decisive in Ritter reaction with nitriles. It was established that the attack on the peri-position of the naphthalene system to form 1H-2-azaphenalene derivatives was possible only for tetralin derivatives. From the naphthalene only benzo[f]isoquinoline derivatives were formed. 相似文献
13.
N. N. Smolyar Kh. Ya. Lopatinskaya A. B. Vasilechko D. A. Lomov Yu. M. Yutilov 《Russian Journal of Organic Chemistry》2007,43(3):417-421
Nitration of 1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one and its N-methyl derivatives at 0–5°C and 60°C gives 5-nitro-and 5,6-dinitro-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones, respectively. The latter can also be obtained by nitration of 5-mononitro derivatives under similar conditions. The nitration of 6-chloro-and 6-bromo-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones and their N-methyl-substituted analogs leads to the formation of the corresponding 6-chloro(bromo)-5-nitro compounds. The same products are formed in the nitration of 5,6-dichloro-and 5,6-dibromo-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones. In this case, the process involves replacement of the halogen atom in position 5 of the pyridine fragment by nitro group. The nitration of 6-bromo-5-methyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one is accompanied by oxidation of the 5-methyl group to carboxy. 相似文献
14.
M. M. Demina P. S. Novopashin G. I. Sarapulova L. I. Larina A. S. Smolin V. S. Fundamenskii A. A. Kashaev A. S. Medvedeva 《Russian Journal of Organic Chemistry》2004,40(12):1804-1809
Reactions of trimethylsilyl azide with 3-trimethylsilyl-2-propynal and 2-propynal were studied. X-Ray analysis of the molecular structure of 4-trimethylsilyl-1H-1,2,3-triazole-5-carbaldehyde showed that the carbonyl group appears in the s-cis conformation with respect to the double C=C bond in the heteroring. The effect of the temperature and polarity of the medium on the ability of 1H-1,2,3-triazole-5-carbaldehyde to undergo dimerization to tricyclic bis-hemiaminals was examined by IR and 1H NMR spectroscopy.__________Translated from Zhurnal Organicheskoi Khimii, Vol. 40, No. 12, 2004, pp. 1852–1857.Original Russian Text Copyright © 2004 by Demina, Novopashin, Sarapulova, Larina, Smolin, Fundamenskii, Kashaev, Medvedeva. 相似文献
15.
Boiling in toluene of 5-(arylmethylidene)pyrimidine-2,4,6(1H,3H,5H)-triones with L-proline and aldehyde led to the formation of previously unknown substituted 1′-arylhexahydro-1H-spiro[pyrimidine-5,2′-pyrrolysine]-2,4,6(1H,3Н,5Н)-triones. 相似文献
16.
17.
Abolfazl Olyaei Mohammad Sadegh Shahsavari Mahdieh Sadeghpour 《Research on Chemical Intermediates》2018,44(2):943-956
An efficient tandem reaction approach is described to prepare novel benzo[f]chromenes from 2,3-dihydroxynaphthalene, malononitrile and aldehydes using 10 mol% guanidine hydrochloride as the catalyst under solvent-free conditions. The method was also extended to the preparation of novel 12H-benzo[5,6]chromeno[2,3-b]pyridines from 2-aminoprop-1-ene-1,1,3-tricarbonitrile instead of malononitrile under the same reaction conditions. The described one-pot three-component reaction is characterized by short reaction times, high-product yield, mild reaction conditions, simple workup procedure, and simple purification. 相似文献
18.
A. Kishore Kumar V. Sunitha B. Shankar T. Murali Krishna Ch. Abraham Lincoln P. Jalapathi 《Russian Journal of General Chemistry》2017,87(9):2011-2020
A series of novel 9-{2-[(1H-1,2,3-triazol-4-yl)methoxy]phenyl}-3,3,6,6-tetramethyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione derivatives were synthesized by a click chemistry approach. The structures of all the newly synthesized compounds were characterized by IR, MASS, 1H and 13C NMR spectral data. The final analogues showed good to excellent antibacterial and antifungal activities in an agar well diffusion assay. Compounds 6i and 6f were the most active against all the test bacterial and fungal strains. 相似文献
19.
I. A. Novakov M. B. Navrotskii E. K. Zakharova L. L. Brunilina 《Russian Chemical Bulletin》2015,64(11):2545-2561
Different approaches to the formation of biologically active isocytosine, uracil, and 2-thiouracil derivatives based on the C(2)-regioselective functionalization of pyrimidin-4(3H)one framework were considered. 相似文献
20.
Viktoria S. Moskvina Olexander V. Turov Volodymyr P. Khilya Myroslav M. Garazd Ulrich M. Groth 《Monatshefte für Chemie / Chemical Monthly》2008,139(11):1391-1396
New functionalized derivatives of 8,8,10-trimethyl-4-phenyl-7,8-dihydro-2H,6H-pyrano[3,2-g]-chromene-2,6-dione – analogues of the natural compound graveolone – possessing hydrazine, hydroxylamine, and thiosemicarbazide
residues were synthesized and their reactions with acetic anhydride were studied. The structure of the obtained compounds
was confirmed by NMR spectroscopy.
Correspondence: Viktoria Moskvina, Chemistry Department, Kyiv National Taras Shevchenko University, 60, ul. Vladimirskaya,
01033 Kyiv, Ukraine. 相似文献