共查询到20条相似文献,搜索用时 93 毫秒
1.
A. V. Aksenov A. V. Sarapii O. A. Antonova I. V. Borovlev V. I. Goncharov 《Chemistry of Heterocyclic Compounds》2005,41(8):1031-1035
The reaction of 1-alkyl-3-(2-quinolyl)quinolinium iodides with excess zinc in THF gives a diastereomeric mixture of 1,1′-dialkyl-3,3′-di(2-quinolyl)-1,1′,4,4′-tetrahydro-4,4′-biquinolyls.
An excess of lithium in THF gives a mixture of 1′,2′-dihydro-2,3′-biquinolyl and 1′-alkyl-1′, 4′-dihydro-2,3′-biquinolyl with
the former predominating. The reduction by lithium in THF of 1,1′-dialkyl-3,3′-di(2-quinolyl)-1,1′,4,4′-tetrahydro-4,4′-biquinolyls
leads to analogous products. Reduction of 1-alkyl-3-(2-quinolyl)quinolinium iodides by metallic potassium gives 1-alkyl-1′,4′-dihydro-2,3′-biquinolyls.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1208–1212, August, 2005. 相似文献
2.
I. Strakova A. Strakovs M. Petrova S. Belyakov 《Chemistry of Heterocyclic Compounds》2007,43(12):1512-1518
The [3+2] cycloaddition reactions of a series of 1,3-substituted 5-diazo-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazoles with
maleic anhydride and dimethyl acetylenedicarboxylate gave 1′,3′-substituted 3-spiro[4,6-dioxo-4,6,3a,6a-tetrahydro-3H-furo[3,4-c]pyrazole]-5′-[6′,6′-dimethyl-4′-oxo-4′,5′,6′,7′-tetrahydroindazoles]
and 1′,3′-substituted 3-spiro[4,5-di(methoxycarbonyl)-3H-pyrazole]-5′-[6′,6′-dimethyl-4′-oxo-4′,5′,6′,7′-tetrahydroindazoles]
respectively. When heated the former eliminate nitrogen and are transformed into 1′,3′-substituted 6-spiro[2,4-dioxo-3-oxabicyclo[3.1.0]hexane]-5′-[6′,6′-dimethyl-4′-oxo-4′,5′,6′,7′-tetrahydroindazoles].
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1784–1791, December, 2007. 相似文献
3.
M. E. Perel'son V. V. Bandyshev Yu. E. Sklyar K. Vezhkhovska-Renke N. V. Veselovskaya M. G. Pimenov 《Chemistry of Natural Compounds》1976,12(5):533-537
Two new terpenoid coumarins — tadzhiferin (I) and tadzhikorin (II) — have been isolated from the fruit ofFerula tadshikorum M. Pimen.
On the basis of physicochemical and spectral investigations, the structure of 7-(9′-hydroxy-3′,7′,11′-trimethyldodeca-2′,6′,10′-trienyloxy)coumarin
is proposed for (I) and that of 7-(4′-acetoxy-9′-hydroxy-3′,7′,11′-trimethyldodeca-2′,6′,10′-trienyloxy)coumarin for (II). 相似文献
4.
T. I. Kulak O. V. Tkachenko O. Yu. Grishan T. A. Kukharskaya L. A. Eroshevskaya E. N. Kalinichenko A. I. Zinchenko 《Chemistry of Natural Compounds》2009,45(1):74-78
A method for chemico-enzymatic synthesis of (2′-5′)-oligonucleotides with 6-N-benzylaminopurineriboside as the nucleoside units was proposed. The method consisted of enzymatic hydrolysis of the oligonucleotides
with mixed (2′-5′)-(3′-5′)-phosphodiesterbonds that were prepared by polymerization of 6-N-benzyladenosine-2′(3′)-monophosphate by using (3′-5′)-specific nuclease and phosphatase contained in the filtrate of culture
medium of the mycelial fungus Spicaria violacea.
Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 64–68, January–February, 2009. 相似文献
5.
A. L. Kurlovich V. A. Tarasevich N. G. Kozlov 《Russian Journal of Organic Chemistry》2009,45(10):1503-1508
Condensation of 2′-hydroxy-1,1′: 3′,1″-terphenyl-5′-carbaldehyde with naphthalen-1-amine and cyclohexane-1,3-dione, methyl
2,2-dimethyl-4,6-dioxocyclohexane-1-carboxylate, or dimedone gave the corresponding 7-(2′-hydroxy-1,1′: 3′,1″-terphenyl-5′-yl)-7,8,9,10,11,12-hexahydro-12H-benzo[c]acridin-8-ones. The reaction of 2′-hydroxy-1,1′: 3′,1″-terphenyl-5′-carbaldehyde with naphthalen-1-amine and indan-1,3-dione
produced 7-(2′-hydroxy-1,1′: 3′,1″-terphenyl-5′-yl)-8H-benzo[h]indeno[1,2-b]quinolin-8-one. 7-(2′-Hydroxy-1,1′: 3′,1″-terphenyl-5′-yl)-7,8,9,10,11,12-hexahydrobenzo[b][1,10]phenanthrolin-8-ones were obtained by three-component condensation of 2′-hydroxy-1,1′: 3′,1″-terphenyl-5′-carbaldehyde
with quinolin-8-amine and cyclohexane-1,3-dione, methyl 2,2-dimethyl-4,6-dioxocyclohexane-1-carboxylate, or dimedone. 相似文献
6.
A. V. Velikorodov O. Yu. Poddubnyi A. K. Kuanchalieva O. O. Krivosheev 《Russian Journal of Organic Chemistry》2010,46(12):1826-1829
1,3-Dipolar cycloaddition to methyl 4-[2-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)-1-oxoethyl]-phenylcarbamate of diazomethane in chloroform-diethyl ether and of 3,4-dimethoxybenzonitrile
oxide generated from the corresponding aldehyde oxime by the action of N-chlorobenzenesulfonamide sodium salt (Chloramine B) in boiling ethanol gave, respectively, methyl 4-(2-oxo-1′,5′-dihydro-1H-spiro[indole-3,4′-pyrazol]-3′-ylcarbonyl)phenylcarbamate and methyl 4-[3′-(3,4-dimethoxyphenyl)-2-oxo-1H,4′H-spiro[indole-3,5′-isoxazol]-4′-ylcarbonyl]phenylcarbamate. The condensation of methyl 4-[2-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)-1-oxoethyl]phenylcarbamate with hydrazine hydrate in ethanol afforded methyl 4-(2-oxo-1,2,2′,4′-tetrahydrospiro[indole-3,3′-pyrazol]-5′-yl)phenylcarbamate. 相似文献
7.
MP2 calculations were used to perform an energy scan of 2-hydroxyadenine (2-OH-A) stacked with four canonical DNA bases. The
structures that were studied correspond to potential energy surface points of B-DNA. Eight stacking complexes were analyzed
in detail: 5′-2-OH-A/A-3′, 5′-2-OH-A/C-3′, 5′-2-OH-A/G-3′, 5′-2-OH-A/T-3′, 5′-A/2-OH-A-3′, 5′-C/2-OH-A-3′, 5′-G/2-OH-A-3′,
and 5′-T/2-OH-A-3′. The stabilization energy, including electron correlation terms, suggests that the 5′-G/2-OH-A-3′ pair
is the most stable among all of the studied complexes. The dependence of the stacking energy on the vertical separation and
on the twist angle between the two stacked bases were studied in great detail. 相似文献
8.
Andrei V. Bogdanov Vladimir F. Mironov Lenar I. Musin Rashid Z. Musin Dmitry B. Krivolapov Igor A. Litvinov 《Monatshefte für Chemie / Chemical Monthly》2011,41(3):81-85
Abstract
The reaction of aminomethylisatins (isatin N-Mannich bases) with hexaethylphosphorous triamide leads to the formation of 1,1′-bis(dialkylaminomethyl)-3,3′-bis(indolin-3-ylidene)-2,2′-diones and 1,1′-bis(1,3-dioxo-1,3-dihydroisoindol-2-ylmethyl)-1H,1′H-[3,3′]bisindolylidene-2,2′-dione. 相似文献9.
M. J. L. Santos A. F. Rubira R. M. Pontes E. A. Basso E. M. Girotto 《Journal of Solid State Electrochemistry》2006,10(2):117-122
Much effort has been made to synthesize novel compounds and enhance the optical properties of poly(terthiophenes). The electrochromic
properties of poly(4,4′′-dimetoxy-3′-methyl-2′-5′,2′′-terthiophene) (PDMMT) and poly(4,4′′-dipentoxy-3′-methyl-2′-5′,2′′-terthiophene)
(PDPMT) have been studied focusing on the differences in the alkoxy-group length. Theoretical calculations were employed to
elucidate the structural and thermodynamic stability of the monomers and dimmers. The results showed that in this type of
thiophenes large alkoxy chains assist positive charge dispersion through hyperconjugative effect. Thus, PDPMT is thermodynamically
more stable than PDMMT in the oxidized state, leading to better electrochromic stability and optical memory. 相似文献
10.
Lutz Preu Wolfgang Kliegel Steven J. Rettig James Trotter 《Monatshefte für Chemie / Chemical Monthly》2001,132(10):1213-1224
Summary. The structure of the dehydrogenation product 1′,3a′-dihydro-3′-((1,3-dioxoindan-2-ylidene)-phenyl-methyl)-5′-phenyl-spiro-(indan-2,1′-pyrrolo[3,4-c]pyrrole)-1,3,4′,6′-(5′H, 6a′H)-tetrone derived from the cycloadducts (±)-(3a′S,6a′R)-1′,3a′-dihydro-3′-((R)-α-(1,3-dioxoindanyl)-benzyl)-5′-phenyl-spiro-(indan-2,1′-pyrrolo[3,4-c]pyrrole)-1,3,4′,6′(5H,6a′H)-tetrone and/or (±)-(3a′S,6a′R)-1′,3a′-dihydro-3′-((S)-α-(1,3-dioxoindanyl)-benzyl)-5′-phenyl-spiro-(indan-2,1′-pyrrolo[3,4-c]pyrrole)-1,3,4′,6′(5H,6a′H)-tetrone, which were synthesized by 1,3-dipolar cycloaddition of N-phenylmaleimide to 2-((2-(1,3-dioxoindan-2-yl)-2-phenyl-ethenyl)-imino)-indan-1,3-dione,
was determined by X-ray analysis. Crystal data (CCD, 180 K): rhombohedral, R&3macr;;, a = 34.0871(7), c = 13.9358(5) ?, Z = 18; the structure was solved by direct methods and refined by full-matrix least-squares procedures to R(F, I ≥ 3σ(I)) = 0.053. The molecule contains a central folded ring system of two cis-fused 5-membered heterocyclic rings; each ring is nearly planar, and the angle between the rings amounts to 59.0°. Dynamic
1H NMR spectroscopy of the product revealed an exchange process caused by restricted rotation of the double bonded 1,3-indandione
moiety and the phenyl group about the Csp2-Csp2 single-bonds. Molecular modeling and complete lineshape analysis indicated a four site exchange process for which free energies
of activation and free energies could be established. ΔG
‡ values for the barriers of rotation are in the range of 57–59 kJ · mol − 1 at 273 K, which is unusually high for an unsubstituted phenyl group.
Received May 3, 2001. Accepted (revised) June 8, 2001 相似文献
11.
A. V. Timshina S. A. Rubtsova I. N. Alekseev P. A. Slepukhin A. V. Kuchin 《Russian Journal of Organic Chemistry》2010,46(3):363-367
(1R,1′R,2S,4R)-1,7,7-Trimethylspiro[bicyclo[2.2.1]heptane-2,2′-[1,3]dithiolane] 1′-oxide, (1R,2S,3′R,4R)-1,7,7-trimethylspiro[bicyclo[2.2.1]heptane-2,2′-[1,3]dithiolane] 1′,1′,3′-trioxide, and (1R,4R)-1,7,7-trimethylspiro[bicyclo[2.2.1]heptane-2,2′-[1,3]dithiolane] 1′,1′,3′,3′-tetraoxide were synthesized by oxidation of
camphor ethylene dithioacetal with m-chloroperoxybenzoic acid at different substrate-tooxidant ratios. The structure of the products was proved by IR and NMR
spectroscopy and X-ray analysis. 相似文献
12.
H. Kažoka A. Krauze M. Vilums L. Černova L. Sīle G. Duburs 《Chemistry of Heterocyclic Compounds》2007,43(6):708-714
The stability of solutions of esters of 6′-carbamoylmethylthio-5′-cyano-2′-methyl-1′,4′-dihydro-4,4′-bipyridine-3′-carboxylic
acids was investigated by HPLC. The corresponding esters of 6′-carbamoylmethylthio-5′-cyano-4,4′-bipyridine-3′-carboxylic
acids,esters of 8-cyano-5-methyl-3-oxo-7-(4-pyridyl)-2,3-dihydro-7H-thiazolo-[3,2-a]pyridine-6-carboxylic acids, methyl 3-amino-2-carbamoyl-6-methyl-4-(4-pyridyl)-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylate,
and methyl 3-amino-2-carbamoyl-6-methyl-4-(4-pyridyl)-thieno[2,3-b]pyridine-5-carboxylate were synthesized as standard compounds
(typical impurities). Analysis by HPLC was realized under the conditions of reverse-phase chromatography. It was established
that solutions of the investigated compounds (with mixtures of acetonitrile with phosphate buffer, having pH values of not
less than 3 and not more than 5, as solvents) are stable for one month when the solutions are stored in a place protected
against light. It is also necessary to use chromatographic systems in which the aqueous components have pH 3–5 during determination
of the purity of the esters of 6′-carbamoylmethylthio-5′-cyano-2′-methyl-1′,4′-dihydro-4, 4′-bipyridine-3′-carboxylic acid
by HPLC in order to separate the analyzed sorbates and their typical impurities more completely.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 841–848, June, 2007. 相似文献
13.
P. A. Slepukhin N. S. Boltacheva V. I. Filyakova V. N. Charushin 《Journal of Structural Chemistry》2011,52(2):443-444
Specific features of the molecular and crystal structures of 1,5-bis-(4′,4′,4′-trifluoro-1′-methyl-3′-oxo-but-1′-enylamino)-3-oxapentane are determined by single crystal XRD. 相似文献
14.
New macrocyclic polyethers, 2,3,5,6-bis-[5′(5′)-chlorobenzo]-1,7,10-trioxacyclododeca-2,5-diene (I), 2,3,5,6-bis-[5′(5′)-chlorobenzo]-1,7,10,13-tetra oxacyclo pentadeca-2,5-diene (II), and 2,3,5,6-bis-[5′(5′)-chlorobenzo]-1,7,10,13,16-penta oxa cyclo octadeca-2,5-dien (III), and macrocylic lactones 2,3,5,6-bis-[5′(5′)-chlorobenzo]-1,7,10,13-tetraoxacyclopentadeca-2,5-diene-8,15-dione (IV) and 2,3,5,6-bis[5′(5′)-chlorobenzo]-1,7,10,13,16-pentaoxacyclooctadeca-2,5-diene-8,18-dione (V) were synthesized. Complexes of ligands III and V with metal cations were prepared. Furthermore, their metal-picrate extraction with some metal salts was attempted. Structures
of the ligands and complexes were confirmed using spectroscopic techniques. 相似文献
15.
Three novel tripodal ligands, N,N′,N′′-tri-(3′-phenylpropionic acid-2′-yl-)-1,3,5-triaminomethylbenzene (Ll), N,N′,N′′-tri-(4′-methylvaleric acid-2′-y1-)-1,3,5-triaminomethylbenzene (L2) and N,N′,N′′-tri-(3′methylvaleric acid-2′-yl-)-1,3,5-triaminomethylbenzene (L3), have been synthesized and fully characterized. The
stabilizing ability of complexes of the three ligands with transition metal ions Cu(II), Ni(II), Zn(II) and Co(II) and rare
earth metal ions La(III), Nd(III), Sm(III), Eu(III) and Gd(III) has been investigated by the pontentiometric method in water
and in aqueous KNO3 (0.1 mol dm−3) at 25.0±0.1 °C, respectively. The results show that there is a great deal of difference between two series of complexes’
stabilities. An explanation of the difference has been given. 相似文献
16.
P. S. Silaichev M. A. Chudinova P. A. Slepukhin A. N. Maslivets 《Russian Journal of Organic Chemistry》2011,47(11):1718-1722
1-Aryl-4,5-bis(methoxycarbonyl)-1H-pyrrole-2,3-diones react with N-substituted 3-amino-5,5-dimethylcyclohex-2-en-1-ones affording methyl 1,1′-diaryl-4′-hydroxy-6,6-dimethyl-2,4,5′-trioxo-1,1′,2,4,5,5′,6,7-octahydrospiro[indole-3,2′-pyrrole]-3′-carboxylates
whose structure was proved by XRD analysis. 相似文献
17.
V. A. Glushkov E. V. Rotermel’ T. F. Odegova Yu. V. Shklyaev 《Russian Journal of Organic Chemistry》2011,47(9):1318-1322
Hydrolytic cleavage of 1-substituted 2-azaspiro[4.5]undeca-1,6,9-trienes in acid medium is accompanied by dienone-phenole
rearrangement with formation of substituted N-[2-(p-hydroxyphenyl)ethyl] carboxylic acid amides. 1,2-Dimethoxy-3-oxo-15-phenyl-14-azadispiro[5.1.5.2]pentadeca-1,4,14-triene
and 2′-R-7a′-methyl-3a′,4′,5′,6′,7′,7a′-hexahydrospiro[cyclohexa[2,5]diene-1,3′-indol]-4-ones undergo analogous cleavage. 相似文献
18.
Synthesis, structures, and properties of spiro[6-azaperimidine-2,4′-cyclohexa-2′,5′-dien]-1′-one derivatives 总被引:1,自引:0,他引:1
V. N. Komissarov E. N. Gruzdeva L. P. Olekhnovich G. S. Borodkin V. N. Khrustalev S. V. Lindeman Yu. T. Struchkov V. A. Kogan V. I. Minkin 《Russian Chemical Bulletin》1997,46(11):1924-1930
The reaction of 5-amino-4-chloroquinolines with 4-amino-2,6-di-tert-butylphenol yielded derivatives of spiro[6-azaperimidine-2,4′-cyclohexa-2′,5′-dien]-1′-one, which exhibit photo-and thermochromic
properties in solutions. The structure of 2′,6′-di-tert-butyl-5,7,9-trimethylspiro[6-aza,-2,3-dihydroperimidine-2,4′-cyclohexa-2′,5′-dien]-1′-one was established by X-ray diffraction
study. The ring-chain isomerization of 2′,6′-di-tert-butyl-5,7-dimethyl-and 2′,6′-di-tert-butyl-5,7,8-trimethylspiro[6-aza-2,3-dihydroperimidine-2,4′-cyclohexa-2′,5′-dien]-1′-ones was studied by dynamic NMR spectroscopy.
Deceased.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2028–2034, November, 1997. 相似文献
19.
N. M. Mikhailova A. N. Levov S. V. Gozun O. O. Timonina F. Toze A. V. Varlamov 《Chemistry of Heterocyclic Compounds》2006,42(10):1291-1295
Cyanoethylation of 9-phenacyl(β-hydroxy-β-phenylethyl-, or acetamido)-4-azafluorenes under conditions of the Michael reaction
occurs regioselectively at position 9. 1-Amino-4-azafluorene under these conditions forms 1-[N,N-di-(β-cyanoethyl)amino)]-(9-β-cyanoethyl)-4-azafluorene.
The cyclization of 9-(β-cyanoethyl)-9-phenacyl-4-azafluorene has been carried out into 1′-cyano-2′-phenylspiro[4-aza-fluorene-9,4′-cyclopentene
and 1′-imino-2′-hydroxybenzylidenespiro[4-azafluorene-9.3′-cyclopentane]-substituted in the five-membered fragment.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1496–1501, October, 2006. 相似文献
20.
V. A. Glushkov G. F. Krainova O. A. Maiorova V. I. Karmanov A. A. Gorbunov P. A. Slepukhin 《Russian Journal of Organic Chemistry》2012,48(4):575-581
Addition of 1,3,3-trimethyl-3,4-dihydroisoquinolines to N-benzylideneanilines gives substituted N-[2-(3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-1-phenylethyl]anilines, whereas 2′,5′,5′-trimethyl-4′,5′-dihydro-4H-spiro[naphthalene-1,3′-pyrrol]-4-one reacts with N-benzylideneanilines along two pathways involving cyclization to substituted 2,3,3a,4,10,11-hexahydrobenzo[f]pyrrolo[2,3-d]quinolin-5(1H)-ones or elimination of the aniline residue with formation of substituted 5′,5′-trimethyl-2-styryl-4′,5′-dihydro-4H-spiro[naphthalene-1,3′-pyrrol]-4-ones. 相似文献