共查询到20条相似文献,搜索用时 15 毫秒
1.
Norbert De Kimpe Laurent De Buyck Roland Verhé Freddy Wychuyse Niceas Schamp 《合成通讯》2013,43(7):575-582
Recently1 we described a convenient synthesis of 1-aryl-2, 2-dichloro-1-alkanones 1 by a reaction sequence involving conversion of the parent alkylarylketones into the corresponding N-cyclohexylketimines, followed by chlorination with N-chlorosuccinimide in carbon tetrachloride to afford N-cyclo-hexyl α,α-dichloroketimines, the latter compounds being hydrolyzed in acidic medium to yield the title compounds 1. The relative inaccessibility of compounds of type 1 in the literature was striking. α,α-Dichloroacetophenones 1 (R=H) are 相似文献
2.
溴化铜的溴代反应结果表明:在反应温度为60℃,原料的摩尔配比为4-氨基-3,5-二氯苯乙酮∶溴化铜=1∶2,反应2.2h合成标题化合物,溴代产率可达95%以上 相似文献
3.
本文报导了氧桥双核钛配合物[TiCl(BZBZ)_2]_2O的晶体结构和分子结构。配合物晶体(分子式C_(60)H_(44)Cl_2O_9Ti_2)属单斜晶系,C2/c空间群,a=21.013(7),b=18.509(2),c=17.493(2),β=91.43(2)°,V=6801.5(?)~3,M_r=1075.72,Z=4,D_x=1.05 gcm~(-3),μ=3.54 cm~(-1),F(000)=2216,R=0.104(1887个可观测衍射)。配合物分子由Ti—O—Ti桥氧骨架构成,有一分子内二重轴通过桥氧原子。对配合物的生成机理作了探讨。 相似文献
4.
Cai Hong XU Zhi Jie ZHANG Yong Min LI Zhi Min ZHENG Ze Min XIE* Center for Molecular Science Institute of Chemistry The Chinese Academy of Sciences Beijing 《中国化学快报》2001,(1)
Recently, the silicon-nitrogen compounds have received more consideration for their attractive application prospects. Both low molecular weight silazane and polysilazane with high molecular weight are widely used in many aspects. For example, in the processing industry of silicone rubber, silizanes not only can be used as "structure-control additives"1, but also can be used to improve the rubber's heat-resistance and mechanical properties; silicon-nitride ceramics can be prepared by pyrolysis … 相似文献
5.
Sakineh Asghari Ahmad Khabbazi Habibi 《Phosphorus, sulfur, and silicon and the related elements》2013,188(11):2451-2456
Triphenylphosphine underwent Michael addition to dialkyl acetylenedicarboxylate and subsequently to the carbonyl group of α-haloketones. Then, these compounds were cyclized to produce the unstable 1, 3-diionicphosphorus compound, which spontaneously lost triphenyl phosphine, and was converted to the functionalized oxetes derivatives. 相似文献
6.
2-Halomethyl derivatives of 3-functionalized 5-tert-butylfurans are phosphorylated underconditions of the Michaelis-Becker, Arbuzov reactions similarly to other halomethylfurans. No effectof the tert-butyl substituent on the yield of the reaction products was found in this case. Contrary to that, the2-methoxymethyl derivative of 3-chloromethyl-5-tert-butylfuran proved to be more thermostable than its analog containing no tert-butyl substituent. As a result, the yield of phosphonate in the Michaelis-Becker reaction under similar conditions increases 2.5 times. The observed stabilization of the furan ring is explained by shielding of its oxygen atom by the tert-butyl group. 相似文献
7.
BAI Fang GAO Guo-wei WANG Yang MEN Jian College of Chemistry Sichuan University Chengdu P. R. China 《高等学校化学研究》2011,(3):422-425
Novel compounds, (3,6-dichloro-2-nitrophenyl)(3-nitrophenyl)methanone(2), (2-amino-3,6-dichloro- phenyl)(3-aminophenyl)methanone(3) and 1-[3-(2-amino-3,6-dichlorobenzoyl)phenyl]-1H-pyrrole-2,5-dione(4), were synthesized from the initial compound 2,5-dichlorobenzophenone(1) and characterized by 1H NMR, 13C NMR, IR, mass spectrum and element analysis, respectively. The single crystal of compound 2 was obtained and determined by X-ray diffraction analysis. The single crystal data illustrates that it belongs to... 相似文献
8.
2,4-Dichloro-3-methyl-6-nitrophenol 2 was prepared by KOH/H2O hydrolysis of a product mixture obtained from chlorination of p-nitrotoluene in the presence of a phase transfer catalyst. A 95–99% yield of 2 based on 2,3,6-trichloro-4-nitrotoluene, 4 (major chlorination product) was achieved in >95% purity. 相似文献
9.
10.
V. A. Ponomarenko N. M. Khomutova A. P. Pavlov 《Chemistry of Heterocyclic Compounds》1967,3(3):305-308
The oxidation, hydrobromination, and bromoacetylation of 1-vinyl-2, 2, 3, 3-tetrafluorocyclobutane are investigated, with a view to preparing its oxide. It is found that the most convenient method of preparing this oxide is acetyl hydroperoxide oxidation of 1-vinyl-2, 2, 3, 3-tetrafluorocyclobutane.The authors wish to thank V. A. Klimova and N. V. Korshun for elementary analyses, and B. V. Lopatina and L. V. Orlova for spectroscopic analyses of the compounds prepared. 相似文献
11.
Summary. The 1:1 reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylates was trapped by fairly strong NH-acids such as carbazole, indole, or pyrrole to yield highly functionalized 1-azadienes and ketenimines. 相似文献
12.
Issa Yavari Hoorieh Djahaniani Farough Nasiri 《Monatshefte für Chemie / Chemical Monthly》2004,11(1):543-548
The 1:1 reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylates was trapped by fairly strong NH-acids such as carbazole, indole, or pyrrole to yield highly functionalized 1-azadienes and ketenimines. 相似文献
13.
Xuejian Li Bangzhong Wang Dr. Dong Li Dr. Jinfeng Zhao Prof. Dr. Jingping Qu Prof. Dr. Yuhan Zhou 《European journal of organic chemistry》2023,26(15):e202201452
An efficient and environmentally friendly methodology for 3,3-dichlorination and 2-oxidation of indole derivatives is described. Using KI as promotor, MCl (M=K, Na) as chlorine source, and oxone as oxidant, the reaction proceeds smoothly affording various functionalized 3,3-dichloro-2-oxindoles in moderate to excellent yields. This strategy can also be extended to 3-substituted indoles. With a broad substrate scope, it is a practical approach to 3,3-disubstituted-2-oxindoles. 相似文献
14.
Tetrachloro-1, 2-benzoquinone and 2, 3-dichloro-1, 4-naphthoquinone react with a series of aryl and alkyl selenolate, generated either by the reaction of Grignard reagents and selenium powder or by the reduction of diselenides with NaBH4, to give 3, 6-diarylseleno-2, 5-dichloro-1, 4-benzoquinones 3 and 2, 3-diarylseleno-1, 4-naphthoquinones 4 in good yields. 相似文献
15.
Naghiyev F. N. Mamedov I. G. Asadov Kh. A. Dorovatovskii P. V. Khrustalev V. N. Maharramov A. M. 《Russian Journal of Organic Chemistry》2019,55(12):1967-1970
Russian Journal of Organic Chemistry - New tetrahydroisoquinoline-5,7-dicarbonitrile derivatives have been synthesized by piperazine hydrate-catalyzed reaction of acetoacetanilide with... 相似文献
16.
Asma Hrizi Manon Cailler Moufida Romdhani-Younes Yvan Carcenac Jrme Thibonnet 《Molecules (Basel, Switzerland)》2021,26(17)
An approach for the preparation of polysubstituted indole-2-carbonitriles through a cross-coupling reaction of compounds 1-(but-2-ynyl)-1H-indole-2-carbonitriles and 1-benzyl-3-iodo-1H-indole-2-carbonitriles is described. The reactivity of indole derivatives with iodine at position 3 was studied using cross-coupling reactions. The Sonogashira, Suzuki–Miyaura, Stille and Heck cross-couplings afforded a variety of di-, tri- and tetra-substituted indole-2-carbonitriles. 相似文献
17.
Issa Yavari Azizollah Habibi 《Phosphorus, sulfur, and silicon and the related elements》2013,188(8):1733-1739
5-Isopropylidene-2,2-dimethyl-1,3-dioxane-4,6-dione (the condensation product of Meldrum's acid and acetone) reacts with alkyl isocyanides in the presence of this to produce S -alkyl 1-alkyl-4,4-dimethyl-2,5-dioxo-pyridine-3-carbothioates in good yield. 相似文献
18.
Rozentsveig G. N. Rozentsveig I. B. Levkovskaya G. G. Mirskova A. N. 《Russian Journal of Organic Chemistry》2003,39(12):1804-1805
Russian Journal of Organic Chemistry - 相似文献
19.
V. I. Dronov G. M. Prokhorov N. S. Lyubopytova 《Chemistry of Heterocyclic Compounds》1970,6(9):1112-1113
Oxidation of 2, 3-dichlorothianaphthene affords 2,3-dichlorothianaphthene-1-oxide. This reacts with methanol, ethanol, and piperidine to give 2-chloro-3-methoxy-, 2-chloro-3-ethoxy-, 2, 3-diethoxy-, and 2-chloro-3-piperidinothianaphthene-1-oxide.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1192–1193, September, 1970. 相似文献
20.
N. G. Khusainova G. R. Reshetkova T. A. Zyablikova R. A. Cherkasov A. N. Pudovik 《Phosphorus, sulfur, and silicon and the related elements》2013,188(1)
Abstract The reactions of the cyclic derivatives of the two-coordinated phosphorus atom - 2-phenyl- and 2 -acetyl-2-H-l,2,3-diazaphospholes, dialkylphosphoe sulphenyklorides, dialkyldithio- and dialkylmonothiophosphates kads to the formation of the new P(III)-fUnctiohalized diazaphosphoknes. 相似文献