共查询到20条相似文献,搜索用时 0 毫秒
1.
《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2017,129(41):12897-12900
A nickel‐catalyzed asymmetric reductive Heck reaction of aryl chlorides has been developed that affords substituted indolines with high enantioselectivity. Manganese powder is used as the terminal reductant with water as a proton source. Mechanistically, it is distinct from the palladium‐catalyzed process in that the nickel–carbon bond is converted into a C−H bond to release the product through protonation instead of hydride donation followed by C−H reductive elimination on Pd. 相似文献
2.
3.
《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2017,129(16):4646-4649
A range of aza‐ullazines, which represent a new heterocyclic core structure, were synthesized through a scalable four‐step reaction, including a Sonogashira reaction and metal‐free cyclization promoted by p‐toluenesulfonic acid. The optical and electrochemical properties of selected derivatives were investigated, they were found to have similar absorption and emission spectra but a higher oxidation potential than the parent ullazine core. 相似文献
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
Xiaogang Tong Bingfei Shi Kangjiang Liang Qian Liu Chengfeng Xia 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2019,131(16):5497-5500
The structural features Kopsia alkaloids, in particular multiple all‐carbon quaternary stereocenters in a caged and strained polycyclic skeleton, poses particular challenges for enantioselective total synthesis. Herein, we reported the first total synthesis of (+)‐flavisiamine F. The synthetic approach involved a room‐temperature Overman rearrangement for introducing the chiral amine at C21, a TMS‐promoted ketal Claisen rearrangement for constructing the all‐carbon quaternary stereocenter at C20, and a late‐stage visible‐light‐induced photochemical cyclization for establishing the all‐carbon quaternary stereocenter at C7. 相似文献
18.
19.