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Objectives/Hypothesis

Cricothyroid approximation (CTA) surgery aims at raising the voice pitch in male-to-female transsexuals. However, 30% of the patients are not satisfied with the result. The purpose of our study was to examine the cricothyroid joint (CTJ) biomechanics and to analyze if (and how) the CTJ anatomy influences the movement of the cricoid and, consequently, the elongation of the vocal fold and the voice pitch after CTA.

Methods

Twenty-four cadaver larynges were examined with high-resolution computerized tomography and MIMICS three-dimensional imaging software (Materialise Interactive Medical Image Control System, Leuven, Belgium). After superimposing the two scans taken in “neutral” and in “CTA” positions, vector geometrical analysis was used to determine the effective rotation axis of the CTJ and to calculate the elongation of the vocal folds after CTA.

Results

Our results showed that the cricoid rotates around an axis, the position of which depends on the anatomical structure of the CTJ. Based on the location of this effective rotation axis, we could distinguish three groups. In group I (N = 13), the rotation axis was located in the lower third; in group II (N = 5), it was located in the middle third; and in group III (N = 6), it was located in the upper third of the cricoid. The elongations of the vocal fold were 12%, 8%, and 3%, in groups I, II, and III, respectively.

Conclusions

The anatomical structure of the CTJ influences directly (1) the position of the effective rotation axis and (2) the elongation of the vocal folds.  相似文献   

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【例1】(2006年全国理综Ⅱ)如图1所示,一固定在竖直平面内的半圆形轨道ABC,其半径R=0.5m,轨道C处与水平地面相切.在C处放一小物块,给它一水平向左的初速度”0=5m/s,结果它沿CBA运动,通过A点,最后落在水平面上的D点,求C、D间的距离,取重力加速度g=10m/s^2.  相似文献   

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New micromanipulation techniques now enable physicists and biologists to study the behavior of single biomolecules such as DNA. In particular, it is possible to measure the elastic response of individual DNA molecules to changes in the double helix's supercoiling. The force versus extension diagram for torsionally relaxed DNA is continuous and allows one to evaluate the persistence length of the polymer. When the molecule is supercoiled, however, stretching leads to the buildup of torsional stress in the double helix's axis. When the twist energy thus generated increases beyond a critical value, the molecule is locally destabilized and changes conformation. This structural transition occurs at stretching forces which can be exerted in vivo by molecular motors and at degrees of supercoiling found in the cell, and may have implications for DNA structure and function within the nucleus.  相似文献   

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The equivalence between the approaches of Drinfeld-Sokolov and Feigin-Frenkel to the mKdV and KdV hierarchies is established. A new derivation of the mKdV equations in the zero curvature form is given. Connection with the Baker-Akhiezer function and the tau-function is also discussed. Received: Received: 1 July 1996 / Accepted: 21 October 1996  相似文献   

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Acoustical Physics - Based on the method of continued boundary conditions, two algorithms for the numerical solution of the problem of plane wave diffraction by a Janus sphere in the form of a...  相似文献   

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在胶子和鬼传播子所满足的耦合的Dyson-Schwinger方程中, 采用裸胶子-鬼顶点, 利用两种重整化方案: 解析延拓方法和减除方法, 得到了胶子和鬼传播子的红外行为. 计算表明两种重整化方案在红外区对胶子和鬼传播子得到一致的结果.  相似文献   

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Acoustical Physics - Modified discrete source method and diagram equation method are used to develop two algorithms for solving a three-dimensional scattering problem in the case of scattering from...  相似文献   

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