六十年的奋斗与耕耘——恭贺徐如人、庞文琴教授执教六十年暨八十华诞

一、吉林大学无机化学学科的创建1952年,徐如人和庞文琴分别从上海交大和东北师大化学系毕业后,即来到刚刚建立理科的东北人民大学(吉林大学前身)任教。他们在关实之教授的领导下与曹锡章、王式正等四位助教通力合作,在非常艰苦的条件下,因陋就简,开设了吉林大学第一个无机     

《分析测试统计方法和质量控制》书讯

正曹宏燕等编著。《分析测试统计方法和质量控制》全书分十三章,七十三万余字,介绍了分析测试及其试验研究中常用的数理统计方法,包括误差和误差的分布、统计检验、方差分析、正交设计、回归分析等统计方法的理论与实践。本书紧密结合国际标准(ISO)、国家标准(GB)及中国合格评定国家认可委员会(CNAS)等有关实     

发现化学之美感悟科学魅力

本文指出化学教学的关键,在于引导学生发现化学之美,感悟科学魅力,激发学生的学习兴趣及创造潜能。全文阐述了化学的外在美、揭示了化学的内在美———化学学科思想 (科学之美 )、崇尚化学家的人生之美及化学教师的人格之美。作者认为：化学教师的人格之美源自“以学生发展为本”的教育理念和对学生及化学教育事业的挚爱。本文旨在倡导广大教师更新教育观念,增强自身素质,升华崇高人格,真正实现化学教学中“教师快乐教学,学生享受学习”。     

《分析测试统计方法和质量控制》书讯

<正>曹宏燕等编著。《分析测试统计方法和质量控制》全书分十三章,七十三万余字,介绍了分析测试及其试验研究中常用的数理统计方法,包括误差和误差的分布、统计检验、方差分析、正交设计、回归分析等统计方法的理论与实践。本书紧密结合国际标准(ISO)、国家标准(GB)及中国合格评定国家认可委员会(CNAS)等有关实     

物理化学家和化学教育家傅鹰的教育之道

介绍了我国著名的物理化学家和化学教育家傅鹰坚定不移的爱国之心, 精益求精的治学之风, 别具一格的教学之道和光风霁月的品德之尊。结合具体的实例阐述了傅鹰的主要教学思想, 包括注重基础教学、化学史实和化学实验, 注重提高学生兴趣和培养创新意识。     

可贵的启示 难得的教材──评郭保章先生的《20世纪化学史》

郭保章先生经数十年辛勤的教学耕耘,积数年之奋力撰写,终于铸就了这本难能可贵的化学史专著《２０世纪化学史》。２０世纪的化学发展之快、范围之广、涉及问题之多,令人目不暇接。要把如此浩繁复杂而绚丽多彩的２０世纪化学编写成一本适合教学和研究的史书,真是谈何容易,如果没有艰辛的阅读和广博的学识,那简直是难以想象的。郭先生虽然年逾七旬,依然宝刀不老。他以专家的敏锐目光捕捉到了２０世纪化学发展的线索,即以至于力学和相对论的建立对现代化学发展的决定性作用为起点,抛开了以往以１９世纪末２０世纪初物理学的三大发现（…     

非平衡非线性化学

概述了非平衡非线性化学的主要研究内容和最新进展,着重介绍了各种非平衡非线性化学现象以及与之有关的非平衡态热力学理论和非线性化学动力理论;介绍一些典型的理论方法和实验手段以及涨落化学的概念;讨论了非平衡非线性化学研究的意义以及与其它科学尤其是生物学的联系。     

试谈分析化学的明天

分析化学是化学学科几大主要二级学科之一 ,曾被认为是“现代化学之母”[1] ,“化学是从分析化学开始的”[2 ] 。但是近年来情况却发生了变化 ,从有人说“不管人们喜欢不喜欢 ,化学正在走出分析化学”[3] ,到 1 981年英国曼彻斯特大学理工学院建立独立的“仪器装置和分析科学系” ,及国内外一些单位相继建立分析科学实验室或研究所 ,出版《分析科学学报》 ,到最近高鸿先生明确宣布“分析化学的现状和发展趋势都在说明分析化学实际上不再是化学的一个分支”[2 ] 。“分析化学已发展到分析科学阶段”在分析化学界几乎已成了共识。　　“化学之…     

“学科德育”视域下的高中化学教学实践——铝和铝合金

课堂教学是落实立德树人根本任务的主要阵地,以“铝和铝合金”知识内容为载体,将化学学科知识、化学学科核心素养与学科德育内容有效融合,通过飞行之“铝”、安全之“铝”、低碳之“铝”、未来之“铝”等4个环节,把德育内容融入化学教学中,提升德育效果。     

以实验引领化学的学习——美国教材《化学:物质与变化》的分析与启示

实验是化学学科的基础,也是化学学习的重要方法。中学化学教材编写如何体现化学的学科特色,实现实验的教学功能,美国高中化学教材《化学:物质与变化》的实验编排独具匠心,凸显了实验地位,使之对化学学习起到引领作用,通过优化实验题材,拓展了化学学习的范围,展示了实验的各种功能,改进着学生的学习方式。     

二氧化碳和丙烯直接合成甲基丙烯酸的NiPMo/TiO2催化剂的研究

用溶胶-凝胶法以磷钼酸(MPA)的镍盐溶液水解钛酸四丁酯制备了NiPMo/TiO2催化剂.使用ICP、 XRD、 TG-DTA、 IR、 TPD-MS和微反应技术研究了催化剂的化学组成、热稳定性、化学吸附性质和催化反应性能.杂多钼酸盐与TiO2通过O2-在TiO2表面发生了键合.在623 K下,杂多阴离子仍保持原有的Keggin结构.CO2在Lewis酸位Ni(Ⅱ)和Lewis碱位Ni-O-Mo的桥氧协同作用下生成CO2卧式吸附态Ni(Ⅱ)←O-(CO)←(O--Ni).丙烯有多种吸附态在催化剂上吸附.在563 K、 1 MPa和空速1500 h-1的反应条件下,丙烯的摩尔转化率为3.2%,产物MAA选择性为95%.     

Synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives

Different approaches for the synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives from simple amino acids have been investigated. A library of 33 precursors for the preparation of N-hydroxy pyrazinones was obtained in moderate to good yields.     

Toward new camptothecins. Part 6: Synthesis of crucial ketones and their use in Friedländer reaction

In the context of the preparation of camptothecin and luotonin A analogs, the synthesis of some key keto-precursors and their use in Friedländer condensation are described. This paper also focuses on the stability of these keto intermediates and emphasizes the major differences between indolizinones and pyrroloquinazolinones series. Noteworthy is also the report of some original structures isolated as by-products of some experiments.     

CoFe2O4自形成磁性液体场致结构化对磁化的影响

The Langevin paramagnetic theory can’t describe the relation between magnetization of ferrofluids and applied magnetic field. The structuralization of ferrofluids, which is considered the main influence factor of the magnetization, is regarded. The part of magnetization works is deposited when the structure is forming. This action influences the magnetization of ferrofluids directly or indirectly. On the base of the “compressing” model, the Langevin function that usually describes the magnetization of ferrofluid is modified, and a well-fitted curve is obtained. An equation of the relation between the equivalent volume fraction after being “compressed” and the intensity of magnetic field is discovered, which approximately describes the process of magnetization. The relation between the approximate initial susceptibility and the volume fraction can be obtained from modified formula.     

Highly regioselective Buchwald–Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries

The highly regioselective Buchwald–Hartwig amination at C-2 of the cheap and readily accessible reagent, 2,4-dichloropyridine with a range of anilines and heterocyclic amines is described. This new methodology is robust and provides a facile access to 4-chloro-N-phenylpyridin-2-amines on 0.25 mol scale. These intermediates undergo a further Buchwald–Hartwig amination at higher temperature to enable rapid exploration of the chemical space at C-4 and to provide a library of 2,4-bisaminopyridines.     

KMnO4-mediated oxidative CN bond cleavage of tertiary amines: Synthesis of amides and sulfonamides

KMnO₄-mediated oxidative CN bond cleavage of tertiary amines producing secondary amine was introduced, which was trapped by electrophiles (acyl chloride and sulfonyl chloride) to form amides and sulfonamides. The reaction could take place at mild condition, tolerating a wide range of function groups and affording products in moderate to excellent yields.     

Chemistry of heterocyclic compounds at the A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, over 50 years (Review)

The review contains a concise historical account and information on the most significant researches undertaken by the staff at the A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences on the Chemistry of Heterocyclic Compounds. Dedicated to Academician of the Russian Academy of Sciences B. A. Trofimov on his 70th jubilee. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1443–1502, October, 2008.     

A general and convenient synthesis of 4-(tosylmethyl)semicarbazones and their use in amidoalkylation of hydrogen,heteroatom, and carbon nucleophiles

A general synthesis of previously unknown semicarbazone-based α-amidoalkylating reagents, 4-(tosylmethyl)semicarbazones, has been developed. The synthesis involved three-component condensation of semicarbazones of aliphatic or aromatic aldehydes with the same or other aldehydes and p-toluenesulfinic acid. The scope and limitations of this reaction were investigated. The compounds obtained were demonstrated to be an efficient α-(4-semicarbazono)alkylating agents. They were reacted with H- (sodium borohydride), O- (sodium methylate), S- (sodium phenylthiolate), N- (pyrrolidine, sodium succinimide), P- (trialkyl phosphites), and C-nucleophiles (sodium diethyl malonate) to give the corresponding products of the tosyl group substitution, 4-substituted semicarbazones, including analogues of nitrofurazone. Among the prepared compounds tested in vitro for antibacterial and antifungal activity, three nitrofuryl-containing semicarbazones exhibited high biological activities with minimum inhibitory concentration (MIC) values of 8–32 μg/mL.     

Sulfur-directed metal-free and regiospecific methyl C(sp3)–H imidation of thioanisoles

Regiospecific and direct imidation of the methyl C(sp³)–H bond of thioanisoles is realized under mild and metal-free conditions with N-fluorobis(benzenesulfonyl)imide as an oxidant and nitrogen source. Proposed mechanism suggests that thionium ion intermediates and a Pummerer-type reaction are involved. The imidation has advantages such as high step-economy, excellent functionality tolerance, and regiospecificity, giving structurally diverse imidation products.     

Synthesis of novel chiral bidentate hydroxyalkyl-N-heterocyclic carbene ligands and their application in palladium-catalyzed Mizoroki–Heck couplings and asymmetric addition of diethylzinc to benzaldehyde

A small library of new chiral bidentate hydroxyalkyl-imidazolium salts 1 is conveniently synthesized on multi-gram scale from inexpensive and commercially available chiral pool amino acids. The corresponding carbenes, generated by deprotonation of imidazolium salts 1, in combination with palladium(II) chloride were tested in the Mizoroki–Heck coupling reaction. The most significant results in terms of yields and reactivities were achieved with low catalyst loading. The catalytic activities of these imidazolium salts were also investigated in the asymmetric addition of diethylzinc to benzaldehyde. The use of MgO nanoparticles as an additive in conjunction with these ligands played a crucial role in increasing the efficiency of these reactions.