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场效应晶体管(Field effect transistor, FET)生化传感器件具有噪声小、功耗低、免标记、易于集成和小型化等优点,在环境监测、食品安全、疾病诊断和临床治疗等领域具有良好的应用前景。二维材料作为新一代FET生化传感器件的沟道材料,具有原子级厚度、高载流子迁移率、高比表面积和可调带隙等特性,可进一步提升FET生化传感器件的性能和拓展器件应用场景,推动FET生化传感器件的快速发展。本文综述了近年来二维材料FET生化传感器件的发展历程和最新进展,分析了二维材料FET生化传感器件的挑战和发展前景,以期为研究人员设计新的生化传感器件提供思路,促进生化传感技术的进一步发展。 相似文献
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核酸适体生物传感器* 总被引:3,自引:0,他引:3
构建高速度、高特异性、高灵敏的蛋白质检测技术是目前蛋白质组学研究所面临的紧迫任务。传统蛋白质的检测主要利用抗体-抗原的特异相互作用。利用寡核苷酸间的严格的识别和亲和力而设计的人工合成寡核苷酸-适体(aptamer)的出现,使抗体抗原反应发生新的革命性变化。核酸适体对蛋白质的结合力和特异性可与抗原抗体间的作用力相媲美,且与抗体相比有许多优越性。因此利用核酸适体构建蛋白质的检测方法己引起许多科学工作者的关注。本文综述了核酸适体的发现(包括SELEX技术的原理),特点, 核酸适体生物传感器的原理、分类和应用,并对核酸适体生物传感器的发展进行了展望。 相似文献
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采用微机械剥离法得到横向尺寸为10μm的碲化锗(GeTe)纳米片.通过电子束曝光和真空溅射镀膜的方法,以钛金合金为接触电极,制备基于二维碲化锗(2D-GeTe)纳米材料的场效应晶体管(FET),并测定了其电学性能.结果表明,剥离所得GeTe纳米材料具有良好的结晶性,光学带隙为1.98 eV,属于p型半导体;该场效应晶体管展现出了6.4 cm2·V-1·s-1的载流子迁移率和670的开关电流比的良好电学性能. 相似文献
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FANG Wensheng HUANG Lei ZAMAN Shahid WANG Zhitong HAN Youjia XIA Bao Yu 《高等学校化学研究》2020,36(4):611-621
Due to their unique electronic and structural properties triggered by high atomic utilization and easy surface modification, two-dimensional(2D) materials have prodigious potential in electrocatalysis for energy conversion technology in recent years. In this review, we discuss the recent progress on two-dimensional nanomaterials for electrocatalysis. Five categories including metals, transition metal compounds, non-metal, metal-organic framework and other emerging 2D nanomaterials are successively introduced. Finally, the challenges and future development directions of 2D materials for electrocatalysis are also prospected. We hope this review may be helpful for guiding the design and application of 2D nanomaterials in energy conversion technologies. 相似文献
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ZHOU Xinyun YANG Juehan ZHONG Mianzeng XIA Qinglin LI Bo DUAN Xidong WEI Zhongming 《高等学校化学研究》2020,36(4):584-596
Two-dimensional(2D) layered materials have attracted great attention due to their unique electrical, optical, thermal and mechanical properties. 2D layered materials have unique van der Waals gaps, thus the foreign substance, such as atoms, molecules and ions, can be inserted into the gaps to change the physical and chemical properties of 2D layered materials, which is conducive to realize their multi-functional application. Herein, we present a critical review of recent research progress of 2D intercalated materials, including the synthesizing methods, theoretical calculation, characterization and multifunctional application. Finally, we will summarize the current challenges and future opportunities in the development of 2D intercalated materials. 相似文献
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《Analytical letters》2012,45(4):672-681
Insulin plays an important role in glucose metabolism and its detection in biological fluids is of interest. In this study, a triple-helix molecular switch was employed for the simple, sensitive, and rapid determination of insulin. The triple-helix molecular switch was composed of a target specific aptamer sequence flanked by two arm segments and a dual-labeled oligonucleotide acting as a signal transduction probe. This approach takes advantage of unique properties of aptamers and triple-helix molecular switches such as high affinity, selectivity, and stability. In the absence of insulin, the fluorescence of triple-helix molecular switch is on. Upon addition of insulin, the aptamer binds to its target, leading to the release of the signal transduction probe, folding of the signal transduction probe to a stem loop structure, and the quenching of the fluorescence. This sensor showed a high selectivity toward insulin and a limit of detection as low as 9.97 nM. The sensor was employed for the determination of insulin in biological samples. This platform may be generalizable for a variety of molecules. 相似文献
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Controlled large-quantity synthesis of two-dimensional materials is vital for the research on their physical and chemical characters and potential applications. Utilizing structural features of layered compounds, intercalation of molecules or ions can be applied to the acceleration of liquid-phase exfoliation. In this review, we aim at recent progress on synthesis of two-dimensional materials via intercalation-assisted exfoliation strategy. Works on wet chemical intercalation and electrochemical intercalation, together with product exfoliation afterwards, are summarized. Furthermore, the features and advantages of intercalation-assisted exfoliation strategy for two-dimensional materials synthesis are discussed. 相似文献
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With the increased energy demand,developing renewable and clean energy technologies becomes more and more significant to mitigate climate warming and alleviate the environmental pollution.The key point is design and synthesis of low cost and efficient materials for a wide variety of electrochemical reactions.Over the past ten years,two-dimensional(2D)nanomaterials that graphene represents have been paid much attention as a class of the most promising candidates for heterogeneous electrocatalysts in electrochemical storage and conversion.Their unique properties,such as good chemical stability,good flexibility,and good electronic properties,along with their nanosized thickness and large specific area,make them exhibit comprehensively good performances for energy storage and conversion.Here,we present an overview on the recent advances in electrochemical applications of graphene,graphdiyne,transition metal dichalcogenides(TMDs),and MXenes for supercapacitors(SCs),oxygen reduction reaction(ORR),and hydrogen evolution reaction(HER). 相似文献
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Highly selective, sensitive, and stable biosensors are essential for the molecular level understanding of many physiological activities and diseases. Electrochemical aptamer-based (E-AB) sensor is an appealing platform for measurement in biological system, attributing to the combined advantages of high selectivity of the aptamer and high sensitivity of electrochemical analysis. This review summarizes the latest development of E-AB sensors, focuses on the modification strategies used in the fabrication of sensors and the sensing strategies for analytes of different sizes in biological system, and then looks forward to the challenges and prospects of the future development of electrochemical aptamer-based sensors. 相似文献
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电催化水分解因其丰富的原料来源和环境友好被认为是一种有前途的制氢技术. 开发用于电催化析氢反应的高效电催化剂是迫切需要的. 随着石墨烯的兴起, 二维(2D)材料因其独特的物理、 化学和电子特性, 已逐渐成为水电解的潜在候选材料. 本文介绍了二维材料用于电化学水分解产生氢气的最新进展, 概括了二维材料的合成方法, 总结了改善二维材料电化学析氢性能的策略, 讨论了该领域面临的挑战和未来的发展机遇. 相似文献
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