New Synthesis of β-Iodostyrenes

A general procedure for the synthesis of -iodostyrenes is proposed. Aromatic aldehyde and ketone hydrazones are converted into the corresponding -iodostyrenes by treatment with CHI₃ in the presence of a catalytic amount of CuCl.     

Synthesis of New F-Alkyl β-Amino Alcohols

F-alkyl oxiranes 1 and p-methylbenzene sulfonate ester intermediates 3 derived from 2-F-alkyl ethane -1,2-diols 2 are converted into F-alkyl β-amino alcohols 5 respectively by a two-step process.     

A New Formal Total Synthesis of β-Elemenone

A short, stereoselective synthesis of an intermediate in Grieco's synthesis of β-elemenone is described.     

A New Asymmetric Synthesis of β-Aminophosphonic Acids

Addition of α-phosphonate carbanions to (S)-sulfinimines 2 gives N-sulfinyl-β-aminophosphonates 3 with a high diastereoselectivity (up to 10:1). The major diastereomer of 3 (R=Ph) was converted into (+)-(R)-β-amino-β-phenylethanephosphonic acid 5.     

Synthesis of New Sulfonamides Based on β-Pinene

Russian Journal of Organic Chemistry - Reactions of pinane-10-sulfonyl chlorides with alkyl-, aryl-, and hetarylamines afforded up to 92% of new chiral sulfonamides that are potentially...     

Synthesis of a New Polysiloxane Modified Polyurethane

It is well known that the polysiloxane polymers possess important physical and chemical properties, such as very good resistance to temperature and oxidant agents, very low glass-transition temperature, high permeability to gases and biocompatibility. But…     

Synthesis of a 1,3,4,5-tetrahydrobenzindole β-ketoester

Pd(OAc)₂-catalyzed decomposition of ethyl 2-diazo-4-(4-indolyl)-3-oxobutanoate leads to a tricyclic tetrahydrobenzindole compound formed by a formal C-H insertion reaction. This tricyclic indole rearranges to a novel and thermodynamically more stable naphthalene derivative. Treatment of N-tosyl-protected ethyl 2-diazo-4-(4-indolyl)-3-oxobutanoate with a base induces facile pyrazole formation.     

Development of a New α‐Aminonitrile Synthesis

Abstract

α‐Aminonitriles are prepared upon reaction of aryl carboxaldehydes with LiHMDS and acetone cyanohydrin. This new method provides a general route to the synthesis of various substituted α‐amino‐arylacetonitriles in high yield and purity, and avoids the use of the highly toxic cyanide salts.     

Synthesis of a New Series of Bone Affinity Compounds

As known that tetracycline possesses bone affinity1, which can be used as carrier of bone-targeting drugs. Chrysophanol is one of the anthraquinone components isolated from Rheum palmatum L., its structure is similar to tetracycline. The bone affinity of …     

First Synthesis of a Series of New Natural Glucosides

Alkyl glucoside 1 and aryl glycosides 2-4 were highly stereospecifically synthesized over 4-6 steps from commercially available starting materials. The coupling reaction of the acetobromo-α-D-glucose with the unprotective dihydroxy aglycon in the presence of silver oxide, or with aromatic aglycon in the presence of sodium hydroxide produced the key intermediate. Only β-configuration glycosides were formed in this procedure. The synthesis of all these glycosides was reported for the first time.     

Synthesis and Stereostructure of New β-Lactam Derivatives of1,5-Benzothiazepines

Becauseoftheimportanceofbenzothiazepinederivatives,whichexhibitversatilebiologicalactivities.thechemistryofbenzothiazepinehasarousedinterestforalongtime'-'.Inourpreviouspapers.wehavereportedthesynthesisandelucidationofthestereostructureoftwokindsofl,5-benzothiazepine-6-lactams'-'.InordertoelucidatetheinfluenceofthesizeofthesubstituentatC-2ontheconfigurationof0-lactammoietyandfurtherstudythestereochemistryofthecycloadditionreaction.wepreparedaseriesofnewfi-lactamderivativesofI.5-benzothiazepine…     

Synthesis of a New Aryl Ether Ketone Polymer

SemicrystallinearyletherketonepolymerssuchasPEEKbelongtoaclassofmaterialsknownasengineeringthermoplastics.PEEKexhibitsarelativelyhighdegreeofcrystallinityandameltingpoint(T.)of335"C.Ontheotherhand,PEEKsuffersfrompoorcreepbehavioraboveitsrelativelylowglasstransitiontemperature(T,)of143"C.Therefore,thesynthesisofnewvariantsisthefocusofmuchresearchl'2.Thesenewvariantsareusuallysemicrystallineinnatureandexhibithighmeltingpoints.Thisresultsinprocessingdifficulties,whichhascreatedaneedforpoly…     

Synthesis of New β-Cyclodextrin Dimers Bridged by Schiff Base

Thecyclodextrindimerisaveryinterestingsupramolecularhostthatcanrecognizeditopicgueststoformvarioussignificantsupramolecularstructures.Althoughmanycyclodextrindimershavebeensuccessfullyprepared',theirsynthesisisstilldifficultandrequirescontinuousefforttoovercome.Sincethepropertiesofacyclodextrindimeraredecideddomnantlybythebridge,itiscriticaltochoosealinkerthathassignificanceandavailability.ConsideringtheinterestingbindingandchromophoricpropertiesoftheSchiffbasemoiety,aswellastheconvenienceofin…     

New Synthesis of β-Anilinochalcones by Regioselective Oxidation of β-Anilinodihydrochalcones Using Iodine–DMSO

β-Anilinodihydrochalcones readily undergo oxidation α to the carbonyl group region in the presence of a catalytic amount of iodine in dimethyl sulfoxide at 130 °C in good yield. Oxidation of allyloxy-substituted β-anilinodihydrochalcones to β-anilinochalcones is a preferred reaction over deallylation.     

Simple and New Method for the Synthesis of β-Acetamido Ketones on a Solid Surface

Diels–Alder reactions of 3-vinylindoles were carried out with methyl acrylate and N-phenylmaleimide as dienophiles under microwave conditions to furnish unreported tetrahydrocarbazoles regio- and stereoselectively in good yields. Further dehydrogenation resulted in new substituted carbazoles.     

Synthesis of a New Chiral Cyclicβ-Amino Alcohol

The enantioselective chiral l,3,2-oxazaborolidine-catalyzed reduction of prochiralketones by borane has been intensively investigated'-'. Most oxazaborolidine catalystshave been prepared from chiral D-amino alcohols. In our previous study on the catalyststructure-enantioselectivity relationships, we prepared (R)-2-amino-1,l-diphenyl-3~(2naphthyl)-l-propanol I which proved to be a good precursor of chiral catalyst for theenantioselective borane reduction of prochiral ketones4-9. This let'ter d…     

Synthesis of a New Polyoxometalate Loaded Stearic Acid Nanoparticles

The stearic acid nanoparticles loaded polyoxometalate K6[γ-(CpTi)2SiW10O38][(CpTi)2SiW10] have been prepared and structurally characterized by elemental analysis, IR spectra.The particle size was estimated by transition electron microscope and zatesizer instrument. The result showed that the polyoxometalate retained the parent structure after encapsulation by stearic acid nanoparticles.     

Synthesis and Characteristics of a New Molybdoantimonate KSbMoO_5

1 INTRODUCTION Great efforts have been made for the discovery of microporous solids due to their rich structural chemi- stry and wide applications in some commercial pur- poses as ion exchanger, absorbent, and catalyst[1]. Since many properties of porous materials depend on their composition and architecture, recent attention has been paid to incorporating other main group and tra- nsition metals into open frameworks, and plenty of materials are reported to contain polyhedra, such as [X…     

Synthesis and Structure of a New Dinuclear Uranyl Complex

Dinuclear complexes have been widely investigated since 1970s when Robson proposed the conception of dinucleating ligand1,2. These compounds attracted much interests because of their applications as metal-enzemy model in bioinorganic chemistry or promising applications as functional materials. Most of these dinuclear complexes contain d transition metals as central ions. Few dinuclear U complexes have been reported. It is known, in most complexes of axial ion, five donors from ligands shou…