Reaction of Substituted 2-Allylthiopyrimidin-4(3H)-ones with Sulfenyl Chlorides

Reaction of substituted 2-allylthiopyrimidin-4(3H)-ones with p-nitrobenzosulfenyl chloride gives the products of addition at the allyl moiety, while the reaction with 2-benzothiazolyl sulfenyl chloride yields thiazolidinopyrimidines with an angular structure.     

Sulfenyl Halides in the Synthesis of Heterocycles. 2. Cyclization in Reactions of Hetarenesulfenyl Chlorides with 3,3-Dimethyl-1-butene

Products of additive cyclization with ring closure at the nitrogen atom of the thiohetaryl unit were synthesized by the interaction of 4,6-dimethylpyrimidine-2-, 3-cyano-4,6-dimethylpyridine-2-, quinoline-8-, and 1,3-benzothiazole-2-sulfenyl chlorides with 3,3-dimethyl-1-butene. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, 893–900, June, 2005.     

Study of the Products from Reaction of 1(2)-Aminoanthraquinones with 1-Chloro-2,3-Epoxypropane

1(2)-(3-Chloro-2-hydroxypropylamino)anthraquinones were synthesized by the reaction of 1(2)-aminoanthraquinones with 1-chloro-2,3-epoxypropane and were then subjected to various transformations.__________Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 505–516, April, 2005.     

1-Chloro-2,6-dinitro-4-perfluoroalkylthiobenzenes in the Synthesis of Heterocycles

1-Chloro-2,6-dinitro-4-perfluoroalkylthiobenzenes was obtained in first time by perfluoroalkylation of bis(4-chloro-3,5-dinitrophenyl)disulfide in the presence of xenon bisperfluoroalkylcarboxylates. At the interaction of these compounds with potassium ethylxanthogenate only substitution of chlorine atom occurred. The reaction with sodium N,N-dimethyldithiocarbamate leads to the nucleophilic substitution of nitro group with formation of 1,3-benzodithiol-2-one, but on action of ethyl thioglycolate the intramolecular condensation occurs with formation of benzothiazoles N-oxides.     

Reaction of 2-Chloro-5-(chloromethyl)thiophene with Monoethanolamine Vinyl Ether

At the alkylation of monoethanolamine vinyl ether with 2-chloro-5-(chloromethyl)thiophene in ethyl alcohol (60-70°C) a product of disubstitution and transvinylation, viz. N,N-bis(5-chloro-2-thienylmethyl)-N-(2-hydroxyethyl)ammonium chloride is formed. The analogous reaction in the absence of solvent proceeds with the formation of N-(5-chloro-2-thienylmethyl)-N-(2-vinyloxyethyl)amine.     

Sulfenyl Halides in the Synthesis of Heterocycles. 1. Heterocyclization in Reactions of 1-Phenyl-5-tetrazolesulfenyl Chloride with Arylolefins

2,3-Dihydrothiazolo[3,2-d]tetrazolium perchlorates have been synthesized by the interaction of 1-phenyl-5-tetrazolesulfenyl chloride with styrene and with (E)-1-phenylpropene in nitromethane in the presence of lithium perchlorate.     

A Synthesis of Dialkyl Phosphorylsuccinates from the Reaction of NH-Acids with Dialkyl Acetylenedicarboxylates in the Presence of Trialkyl(aryl) Phosphites

Summary. The reaction of dialkyl acetylenedicarboxylates with trialkyl(aryl) phosphites in the presence of isatin, phthalimide, indole, or pyrrole leads to stable dialkyl(aryl) phosphorylsuccinates in excellent yields.     

Reaction of 2-Chloro-5(6)-nitrobenzimidazole with Cloromethylthiirane and Isomeric Composition of the Products

The alkylation of 2-chloro-5(6)-nitrobenzimidazole with 2-chloromethylthiirane was studied for the first time. Depending on the conditions, isomeric mixtures of nitro-substituted 2-chloro-1-(thietan-3-yl)benzimidazoles and dihydrothiazolo[3,2-a]benzimidazoles were obtained.     

Reaction of Indium with Tricarbonylcyclopentadienyl-molybdenum(II) and -tungsten(II) Chlorides

The reactions of indium with tricarbonylcyclopentadienyl-molybdenum(II) and -tungsten(II) chlorides in donor solvents result in formation of compounds containing Mo-In and W-In bonds. The formalkinetic features of the metal oxidation with ⁵-C₅H₅Mo(CO)₃Cl in dimethylformamide were studied.     

Synthesis of Three‐Membered and Four‐Membered Heterocycles with the Assistance of Photochemical Reactions

Some transformations are not possible with ground‐state reactions even in the presence of a catalyst; hence, they are performed under photochemical conditions. Electron transfer occurred even with the photochemical excitement of one molecule where redox reaction is not possible at the ground state. The side products were obtained from ground‐state reactions. For C─C bond formation during photochemical reactions, there was no requirement of any chemical activation of the substrates. Therefore, these reactions are presented here for the synthesis of three‐membered and four‐membered heterocycles in the context of sustainable processes.     

Reaction of Methyl 5(6)-(4-Aminophenylthio)-2-benzimidazolylcarbamate with Carboxylic Acid Chlorides

Methyl 5(6)-(4-aminophenylthio)-2-benzimidazolylcarbamate was reacted with carboxylic acid chlorides to obtain mono- and disubstitution products. The formation of the former involves the aniline nitrogen and of the latter, both the aniline and benzimidazole nitrogens. Biological properties of the products are studied.     

Magnesium Sulfate Catalyzed Intermolecular Wittig Reaction of Dialkyl 2-(1-acetyl-2-oxopropyl)-3-(triphenylphosphoranylidene) Succinates with Ninhydrin in Solvent-Free Conditions

A facial one-pot stereoselective synthesis of dialkyl 3,3-diacetyl-3 a -hydroxy-8-oxo-2,3,3 a ,8-tetrahydrocyclopenta[ a ]indene-1,2-dicarboxylates in fairly high yields by the intermolecular Wittig reaction of dialkyl 2-(1-acetyl-2-oxopropyl)-3-(triphenylphosphoranylidene) succinates and ninhydrin in the presence of MgSO 4 in solvent-free conditions at 100°;C is reported.     

Base-Catalyzed Intramolecular Cycloaddition of Dialkyl(4-hydroxybut-2-yn-1-yl)[3-(4-bromophenyl)prop-2-yn-1-yl]ammonuim Chlorides and Recyclization of the Products

Russian Journal of Organic Chemistry - Dialkyl(4-hydroxybut-2-yn-1-yl)[3-(4-bromophenyl)prop-2-yn-1-yl]ammonium chlorides in the presence of 2 equiv of potassium hydroxide at room temperature...     

Microwave Induced Reaction of Dialkyl 2-(1-Acetyl-2-Oxopropyl)-3-(triphenylphosphoranylidene) Succinates with Ninhydrin in the Presence of Magnesium Sulfate in Solvent-Free Conditions

Microwave catalyzed one-pot stereoselective synthesis of dialkyl 1,1-diacetyl-8 a -hydroxy-8-oxo-1,2,8,8 a -tetrahydrocyclopenta[ a ]indene-2,3-carboxylates in fairly high yields by the reaction of dialkyl 2-(1-acetyl-2-oxopropyl)-3-(triphenylphosphoranylidene) succinates and ninhydrin in the presence of MgSO 4 in solvent-free conditions.     

氯化铯催化羧酸钠(钾)与α-氯代乙酸酯及溴(氯)代烃反应

以DMF为溶剂,在催化量氯化铯存在下,羧酸钠(钾)与α-氯代乙酸酯在室温下反应及其与溴(氯)代烃在60℃反应,分别形成对应的羧酸(α-烷氧甲酰)甲酯与羧酸酯,产率90%以上,讨论了催化机理.     

新显色剂2－氯－5－羧基苯基重氮氨基偶氮苯的合成及与镉显色反应的研究

本文报道了新显色剂２－氯－５－羧基苯基重氮氨基偶氮苯（ＣＣＤＡＡ）的合成。研究了在ｐＨ９．８硼砂－氢氧化钠介质中、在ＴｒｉｔｏｎＸ－１００存在下镉（Ⅱ）与ＣＣＤＡＡ形成稳定的红色配合物，λ＿（ｍａｘ）＝４８５ｎｍ，ε＿（１８５）＝１．２４×１０￣５Ｌ．ｍｏｌ￣（－１）、ｃｍ￣（－１），镉量在０～１０μｇ／２５ｍＬ范围内遵守比尔定律。本法灵敏度高，选择性好，已用于测定工业废水中微量镐（Ⅱ），结果满意。     

Quantum-chemical Analysis of Reactions between Alkenes and Sulfenyl Chlorides. Position of Episulfuran and Tight Ion Pair on the Reaction Coordinate

In the first stage the reaction between 3,3-dimethyl-1-butene and 1-phenyl-5-tetrazolylsulfenyl chloride gives rise to intermediate of tight ion pair type that, in the course of system movement along the reaction coordinate, transforms into an intermediate species of sulfuran type or directly into an adduct. The intermediate of sulfuran type also transforms into an adduct going over the energy barrier of 40 kcal mol^-1. The formation of an episulfuran type intermediate directly from the reagents requires overcoming an energy barrier that is by 10 kcal mol^-1 higher than in going through a tight ion pair.