共查询到20条相似文献,搜索用时 15 毫秒
1.
Masato Mizutani Yuzuru Sanemitsu Yoshinao Tamaru Zen-Ichi Yoshida 《Tetrahedron》1985,41(22):5289-5293
The S → N allylic transposition of 4-allylthiopyrimidin-2(lH)-ones 4 and 5-allylthio-1,2,4-triazin-3(2H)-ones 5 has been performed successfully by catalysis of palladium(II) salts. In both cases the N-alkylated products (6 and 7) are obtained with no traces of the C-alkylated products. 相似文献
2.
D. L. Lipilin A. M. Churakov Yu. A. Strelenko V. A. Tartakovsky 《Russian Chemical Bulletin》2006,55(2):357-361
A preparative method for the synthesis of 2-alkyl-1,2,4-benzotriazin-3(2H)-ones 3 was developed. The method involves treatment with sodium cyanate of 2-alkylbenzotetrazinium tetrafluoroborates, which exist
in solutions in equilibrium with o-(alkylazo)aryldiazonium tetrafluoroborates. Reduction of compounds 3 with zinc in acetic acid afforded 2-alkyl-1,4-dihydro-1,2,4-benzotriazin-3(2H)-ones.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 346–349, February, 2006. 相似文献
3.
Condensation of 2,3-diaminopyridine ( 1 ) with ethyl o-, m- and p-substituted benzoylpyruvates 2–9 gave two isomeric products. The preferential formation of one or the other isomer has been achieved by different reaction conditions. All the products appear to exist in the enamine form as evidenced by their 1H nmr and ir spectra. 相似文献
4.
Katritzky AR Odens HH Zhang S Rostek CJ Maender OW 《The Journal of organic chemistry》2001,66(20):6792-6796
Nucleophilic additions of alpha-mercaptoalkanoate esters and beta-mercaptoalkanoate acids to benzoquinone diimines, followed by cyclization with trifluoroacetic acid or 1,3-dicyclohexylcarbodiimide (DCC), provide novel, high-yielding syntheses of 2H-1,4-benzothiazin-3(4H)-ones (3a-f) and 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones (5a-c), respectively. 相似文献
5.
A. S. Fisyuk Y. P. Bogza N. V. Poendaev D. S. Goncharov 《Chemistry of Heterocyclic Compounds》2010,46(7):844-849
A method has been developed for the synthesis of 3-S-hetaryl-substituted pyridin-2(1H)-ones and 5,6-dihydropyridin-2(1H)-ones
based on the base catalyzed cyclization of N-(3-oxoalkyl)- and N-(3-oxoalkenyl)amides which contain a divalent sulfur atom
in an α-position to a carbamoyl group and bound to the heterocycle. 相似文献
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7.
Takehiko Nishio Katsuhiro Katahira Akira Kato Choji Kashima Yoshimori Omote 《Tetrahedron letters》1979,20(43):4211-4212
Irradiation of N-aryl-2(1H)-pyrimidin-2-ones (-) in a mixed benzene-alcohol solution afforded the products initiated by Type I cleavage, 1-(3-alkoxycarbonylamino-2-propene)-N-arylimines (-, , and ) in 45–51% yields. 相似文献
8.
B. P. Bandgar 《合成通讯》2013,43(12):2065-2068
Synthesis of quinazolin-4-(3H)-ones from o-amidobenzonitriles has been carried out by using urea-hydrogen peroxide as a mild, stable and non-hazardous reagent. 相似文献
9.
B. A. Puodzhyunaite R. A. Yanchene P. B. Terent'ev K. A. Abdurakhmanov G. Dzhumakuliev 《Chemistry of Heterocyclic Compounds》1992,28(7):798-802
Alkylation of 4-methyl-7(8)-nitro-2,3,4,5-tetrahydrobenzodiazepin-2-ones under phase transfer catalytic conditions or in dry acetone occurs only at position 1. The 5-alkyl isomers are obtained by reductive alkylation of 4-methyl-7(8)-nitro-2,3-dihydro-1,5-benzodiazepin-2-ones. The UV, IR, PMR, and mass spectra of the isomeric compounds are reported.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 959–963, July, 1992. 相似文献
10.
Jeffery B. Press Victor T. Bandurco Elizabeth M. Wong Zoltan G. Hajos Ramesh M. Kanojia Robert A. Mallory Edward G. Deegan James J. Mcnally Jerry R. Roberts Mary Lou Cotter David W. Graden John R. Lloyd 《Journal of heterocyclic chemistry》1986,23(6):1821-1828
Synthesis of 5,6-dimethoxyquinazolin-2(1H)-one derivatives was the subject of investigations leading to the preparation of title compounds 11, 13, 14 and 26 . Target quinazolines 1 were synthesized in three ways; the route starting from o-vanillin via the intermediacy of 6-amino-2,3-dimethoxyacetophenone ( 19 ) was used for most of the preparative work. The unexpected formation of an acid-labile dimer of 13 was discovered and solid state 13C nmr was used for structural assignment. The 5-methoxy substituent in these systems shows anomalous spectral characteristics and, in one case, was cleaved in acid media to 22 . 相似文献
11.
探讨了在微波加热条件下,芳香醛、取代苯乙酮和尿素的三组分反应在N,N-二甲基甲酰胺(DMF)中制得4,6-二芳基-3,4-二氢嘧啶-2(1H)-酮类化合物,收率为68%~84%.若在反应体系中加入三甲基氯硅烷,该三组分反应则高产率(66%~87%)地生成相应的脱氢产物4,6-二芳基嘧啶-2(1H)-酮类化合物.该反应具有反应条件温和、产物收率高、操作方便等优点,为4,6-二芳基-嘧啶-2(1H)-酮类药物中间体的合成提供了一条全新的路线. 相似文献
12.
13.
Data on methods for the production of 5,6-dihydropyridin-2(1H)-ones and 5,6-dihydropyridine-2(H)-thiones and their biological activity are reviewed.Omsk State University, Omsk, Russia. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 147–167, February, 1999. 相似文献
14.
15.
《中国化学快报》2022,33(8):4057-4060
Herein, we report a practical electro-reductive protocol for the direct C–H cyanoalkylation of quinoxalin-2(1H)-ones via iminyl radical-mediated ring opening. These mild reactions proceed under metal-, reductant-, and reagent-free conditions to provide synthetically useful cyanoalkylated quinoxalin-2(1H)-ones. 相似文献
16.
N. N. Romanova V. A. Budylin G. V. Grishina V. M. Potapov V. N. Torocheshnikov M. L. Demchuk Yu. G. Budel' 《Chemistry of Heterocyclic Compounds》1984,20(12):1354-1357
Phase-transfer catalyzed cyclization of racemic and optically active N-substituted -aminoacids has given racemic and optically active 2-azetidinones, the spatial structures of which have been established by NMR spectroscopy. The original -aminoacids were obtained by adding -phenylethylamine to substituted acrylic acids.Deceased.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1644–1647, December, 1984. 相似文献
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18.
Robert Weis Armin Presser Werner Seebacher 《Monatshefte für Chemie / Chemical Monthly》2003,12(9):1129-1136
3-Carboxamides and 3-carboxanilides of 6-alkyl and 6-aryldihydropyridin-2(1H)-ones have been prepared via different reaction pathways. All synthesized amides show hydrogen bonds in their NMR spectra. The 4-hydroxy compounds were obtained as a mixture of tautomers. Their configurations were elucidated by NMR experiments. 相似文献
19.
Yana Yu. Shmoylova Yuri A. Kovygin Irina V. Ledenyova Mikhail A. Prezent Elena D. Daeva Sergey V. Baranin Khidmet S. Shikhaliev 《Mendeleev Communications》2021,31(2):259-261
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20.
DBU-promoted cyclization of ortho-(3-hydroxy-1-alkynyl)benzamide is presented, providing an efficient method for the synthesis of trans-3,4-dihydroisoquinolin-1(2H)-ones and (E)-4-(1-alkenyl)isoquinolin-1(2H)-ones under mild conditions. 相似文献