Molecularly Imprinted Polymers with Bi-functional Monomers of Polymerizable Cyclodextrin Derivatives and 2-（Diethylamino）ethyl Methacrylate for Recognition of Norfloxacin in Aqueous Media

Molecular imprinting technique is one of the most promising methodologies for synthesizing artificial receptors and has already demonstrated their potential for the separation and analytical application1-6. In the case of molecularly imprinted polymers pr…     

硅基催化结构合成的策略

Two approaches to synthesize silicon-based catalytic structures that aim at capturing the properties and functionalities of natural enzymes are described in this brief review:unit-by-unit synthesis of macromolecular units and templating/imprinting synthesis of nanocages. The unit-by-unit approach mimics the peptide synthesis method,offers atomic control of the structure,but is inefficient in synthesizing large structures such as nanocages. The templating/imprinting method is more suitable for nanocages at the sacrifice of atomic control,and the nanocages obtained are shown to possess properties exhibited by enzyme cavities.     

Surface-imprinted polymers in microfluidic devices

Molecularly imprinted polymers are generated by curing a cross-linked polymer in the presence of a template. During the curing process, noncovalent bonds form between the polymer and the template. The interaction sites for the noncovalent bonds become "frozen" in the cross-linking polymer and maintain their shape even after the template is removed. The resulting cavities reproduce the size and shape of the template and can selectively reincorporate the template when a mixture containing it flows over the imprinted surface. In the last few decades the field of molecular imprinting has evolved from being able to selectively capture only small molecules to dealing with all kinds of samples. Molecularly imprinted polymers (MIPs) have been generated for analytes as diverse as metal ions, drug molecules, environmental pollutants, proteins and viruses to entire cells. We review here the relatively new field of surface imprinting, which creates imprints of large, biologically relevant templates. The traditional bulk imprinting, where a template is simply added to a prepolymer before curing, cannot be applied if the analyte is too large to diffuse from the cured polymer. Special methods must be used to generate binding sites only on a surface. Those techniques have solved crucial problems in separation science as well as chemical and biochemical sensing. The implementation of imprinted polymers into microfluidic chips has greatly improved the applicability of microfluidics. We present the latest advances and different approaches of surface imprinting and their applications for microfluidic devices.     

Simultaneous Chiral Separation Using a Combinatorial Molecular Imprinting Phase

Molecular imprinting is a technology by which specific recognition sites can be producedby using a template molecule in the polymerization procedure. In recent years,molecular imprinting has become an important approach for the preparation of chiralstationary phase with predetermined selectivity'-'. So far, the commonly atilizedfunctional monomers include methacrylic acid', acrylamide' and 4-vinylpyridine',combined functional monomers such as methacrylic acid 2-vinylpyridine'-' andacrylamide…     

Preparation of quercetin imprinted core-shell organosilicate microspheres using surface imprinting technique

In this work,the quercetin imprinted core-shell microspheres were prepared using silica surface imprinting technique.A simple sol-gel procedure was used for the synthesis of the imprinted materials with 3-aminopropyltriethoxysilane as functional monomer and tetraethyl orthosilicate as crosslinker.The SEM images indicated that the MIPs shell was successfully grafted onto the silica surface.The characteristics of the molecularly imprinted polymers such as capacity,selectivity and absorption dynamic were investigated by rebinding experiments.The results showed that the prepared MIPs had good imprinting effect and adsorption amount of quercetin.     

An ion-imprinted polymer supported by attapulgite with a chitosan incorporated sol-gel process for selective separation of Ce(Ⅲ)

The surface ion-imprinting concept and chitosan incorporated sol-gel process were applied to the synthesis of a new attapulgitesupported polymer for selective separation of Ce(Ⅲ) from aqueous solution.The imprinting mechanism of prepared ion-imprinted polymer were discussed with the Characteristics of FT-IR and SEM.Results from the experiments of adsorption capacity and selectivity suggested that ion-imprinted polymer offered a fast kinetics for the adsorption of Ce(Ⅲ) under the optimum conditions. Its m...     

Preparation of hydrophilic molecularly imprinted polymers for tetracycline antibiotics recognition

Hydrophilic molecularly imprinted polymers(MIPs) were prepared using tetracycline as template,methacrylic acid as monomer and glycidilmethacrylate as pro-hydrophilic co-monomer.Compared with common MIPs,the imprinting effect and adsorption amounts of hydrophilic MIPs for tetracycline(TC) were greatly improved in water media.Furthermore,the electrochemical sensor fabricated by modifying hydrophilic MIPs on glassy carbon electrode was developed for the determination of TC in foodstuff samples.     

Molecular imprinting of protein by coordinate interaction

In this article,a novel strong interaction by forming complex between bovine serum albumin(BSA) and copper ion was utilized for the preparation of molecular imprinted hydrogel in aqueous solution.Results show that the inclusion of copper ion in preparation can bridge the template BSA and functional monomers together and improve the imprinting effect compared to the polymer made without copper ion added.High selectivity factor and large adsorption capacity are also observed for the obtained BSA-imprinted ...     

RECENT ADVANCES IN THE PREPARATION OF MOLECULARLY IMPRINTED POLYMERS VIA CONTROLLED RADICAL POLYMERIZATION TECHNIQUES

Molecular imprinting technique is a simple and efficient method for the preparation of polymer materials （i. e., molecularly imprinted polymers, MIPs） with tailor-made recognition sites for certain target molecules. The resulting MIPs have proven to be versatile synthetic receptors due to their high specific recognition ability, favorable mechanical, thermal and chemical stability, and ease of preparation. Recent years have witnessed significant progress in the synthesis and applications of MIPs. This review focus on the recent developments and advances in the preparation of MIPs via various controlled radical polymerization techniques.     

Preparation of imprinted monolithic column under molecular crowding conditions

Molecular crowding is a new concept to obtain molecularly imprinted polymers(MIPs) with greater capacity and selectivity.In this work,molecular crowding agent was firstly applied to the preparation of MIPs monolithic column.A new polymerization system based on molecular crowding surrounding was developed to prepare enrofloxacin-imprinted monolith,which was composed of polystyrene and tetrahydrofuran.The result showed that the monolithic MIPs under molecular crowding conditions presented good molecular recognition for enrofloxacin with an imprinting factor of 3.03.