共查询到20条相似文献,搜索用时 375 毫秒
1.
A. Yu. Dubovtsev A. A. Moroz M. V. Dmitriev A. N. Maslivets 《Russian Journal of Organic Chemistry》2016,52(4):546-552
Methyl 3-aroyl-1-aryl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates reacted with arylhydrazines to give methyl 3-aroyl-1-aryl-2-(2-arylhydrazinyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxylates which underwent thermal recyclization into isomeric methyl 1-aryl-5-(arylcarbamoyl)-4-aroyl-1H-pyrazole- 3-carboxylates and methyl 1,5-diaryl-4-[2-oxo-2-(arylamino)acetyl]-1H-pyrazole-3-carboxylates. 相似文献
2.
N. L. Racheva Z. G. Aliev M. A. Belova I. V. Mashevskaya A. N. Maslivets 《Russian Journal of Organic Chemistry》2008,44(5):701-705
3-Aroyl-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones react with substituted alkyl 3-amino-2-propenoates to form substituted alkyl 3-aroyl-4-hydroxy-1-o-hydroxyphenyl-5-oxo-2,5-dihydro-1H-pyrrole-2-spiro-3′-(2-oxo-2,3-dihydro-1H-pyrrole-4-carboxylates). Crystal and molecular structure of ethyl 3-benzoyl-4-hydroxy-1-o-hydroxyphenyl-5-oxo-2,5-dihydro-1H-pyrrole-2-spiro-3′-(5-methyl-2-oxo-2,3-dihydro-1H-pyrrole-4-carboxylate) was investigated. 相似文献
3.
Yu. N. Bannikova Yu. S. Rozhkova Yu. V. Shklyaev A. N. Maslivets 《Russian Journal of Organic Chemistry》2008,44(5):697-700
Methyl 1-aryl-3-aroyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates reacted with substituted 1-methyl-3,4-dihydroisoquinolines with the formation of substituted 3-oxo-2,3,5,6-tetra-hydropyrrolo[2,1-a]-isoquinoline-2-spiro-2′-(1-aryl-3-aroyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrroles). A new approach was developed to the synthesis of 13-azagonanes, substituted benzo[f]pyrrolo[2,1-a]isoquinoline-9-spiro-2′-pyrroles. 相似文献
4.
V. V. Konovalova K. A. Galata Yu. V. Shklyaev A. N. Maslivets 《Russian Journal of Organic Chemistry》2013,49(11):1666-1669
3-Aroylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react with 1,3,3,7,9-pentamethyl-2-azaspiro-[4.5] deca-1,6,9-trien-8-one and 2′,5′,5′-trimethyl-4′,5′-dihydro-4H-spiro[naphthalene-1,3′-pyrrol]-4-one providing 3-aroyl-2-hydroxy-3a-{(3,3,7,9-tetramethyl-8-oxo-2-azaspiro[4.5]deca-1,6,9-trien-1-yl)methyl}pyrrolo[1,2-a-quinoxaline-1,4(3a H,5H)-diones and 3-aroyl-2-hydroxy-3a-{(5′,5′-dimethyl-4-oxo-4′,5′-dihydro-4H-spiro[naphthalene-1,3′-pyrrol]-2′-yl)methyl}pyrrolo[1,2-a]-quinoxaline-1,4(3aH,5H)-diones. 相似文献
5.
Methyl 3-aroyl-1-aryl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates reacted with 3-amino-5,5-dimethylcyclohex-2-en-1-one having no substituent on the nitrogen atom to give 3-aroyl-4-arylamino-6′,6′-dimethyl-6′,7′-dihydro-5H-spiro[furan-2,3′-indole]-2′,4′,5′(1′H,5′H)-triones or methyl 12-aroyl-11-aryl-9-hydroxy-5,5-dimethyl-3,10-dioxo-8,11-diazatricyclo[7.2.1.02,7]dodec-2(7)-ene-1-carboxylates. The latter underwent thermal recyclization to 3′-aroyl-1′-aryl-4′-hydroxy-6,6-dimethyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-triones. 相似文献
6.
A. V. Velikorodov A. K. Kuanchalieva V. A. Ionova 《Russian Journal of Organic Chemistry》2011,47(11):1715-1717
By the reaction of methyl {4(3)-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetyl]phenyl} carbamates with ethyl 3-aminocrotonate at boiling in the mixture toluene-anhydrous ethanol,
2: 1, ethyl 5-{3(4)-[(methoxycarbonyl)amino]phenyl}-2-methyl-4-(2-oxo-2,3-dihydro-1H-indol-3-yl)-1H-pyrrole-3-carboxylates were obtained. The condensation of methyl {3(4)-[2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetyl] phenyl}carbamates with ethyl acetoacetate in the presence of ammonium acetate and 20 mol% of 1-methyl-3-butylimidazolium
chloride or 1-methyl-3-octylimidazolium tetrafluoroborate at boiling in anhydrous ethanol led to the formation of the corresponding
3-pyrrol-3′-yloxindoles with a carbamate function. 相似文献
7.
E. S. Denislamova A. Yu. Dubovtsev P. A. Slepukhin A. N. Maslivets 《Russian Journal of Organic Chemistry》2014,50(7):1017-1021
Methyl 1-aryl-3-aroyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates reacted with methyl 2-arylamino-4-(2-naphthyl)-4-oxobut-2-enoates to give methyl 1,7-diaryl-4-aroyl-3-hydroxy-9-(2-naphthalen-2-ylcarbonyl)-2,6-dioxo-1,7-diazaspiro[4.4]nona-3,8-diene-8-carboxylates. 相似文献
8.
V. P. Sheverdov M. A. Mar’yasov V. V. Davydova O. E. Nasakin P. V. Dorovatovskii V. N. Khrustalev 《Russian Journal of General Chemistry》2017,87(7):1490-1494
Reaction of methyl 2,4-dioxobutanoates with tetracyanoethylene yielded methyl 3-acyl-4-cyano-5-(dicyanomethylene)-2-hydroxy-2,5-dihydro-1H-pyrrole-2-carboxylates. X-Ray diffraction data showed that 3-acyl-4-cyano-5-(dicyanomethylene)-2-hydroxy-2,5-dihydro-1H-pyrrole-2-carboxylic acid methyl esters can form supramolecular structures with one-dimensional channels which make possible inclusion of large organic and bioorganic molecules. 相似文献
9.
N. I. Makarova E. N. Shepelenko O. G. Karamov A. V. Metelitsa V. A. Bren’ V. I. Minkin 《Russian Chemical Bulletin》2014,63(1):109-114
New nonsymmetrical dihetarylethenes, 3-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)-4-(3-thienyl)furan-2,5-dione and 1-alkyl- and (1-aryl)-3-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)-4-(3-thienyl)-1H-pyrrole-2,5-dione, exhibiting photochromic properties in solutions were synthesized. Noncyclic isomers of dihetarylethenes show fluorescence with quantum yields up to 0.13. 相似文献
10.
Uroš Urši? 《Tetrahedron》2010,66(24):4346-1445
(2E,3Z)-2-(1-Methyl-2,5-dioxoimidazolidin-4-ylidene)-3-[(arylamino- or heteroarylamino)methylene]succinate 5 obtained by [2+2] cycloaddition of (5Z)-5-[(dimethylamino)methylene]-3-methylimidazolidine-2,4-dione (1) and dimethyl acetylenedicarboxylate (2) followed by substitution of the dimethylamino group with aromatic or heteroaromatic amines, afforded by heating in ethanol in the presence of potassium hydroxide, potassium salts 6. Acidification of 6 with hydrochloric acid afforded mixtures of (E)- and (Z)-isomers of methyl 4-(2-hydroxy-1-methyl-5-oxo-1H-imidazol-4(5H)-ylidene)-5-oxo-1-phenyl-4,5-dihydro-1H-pyrrole-3-carboxylates. On the other hand, alkylation of compounds 6 with methyl iodide or benzyl bromide produced the corresponding methyl (E)-4-(2-methoxy- or 2-benzyloxy-1-methyl-5-oxo-1H-imidazol-4(5H)-ylidene)-5-oxo-1-phenyl-4,5-dihydro-1H-pyrrole-3-carboxylates 9, derivatives of a new triazafulvalene system. 相似文献
11.
I. V. Mashevskaya I. G. Mokrushin L. V. Kuslina Z. G. Aliev A. N. Maslivets 《Russian Journal of Organic Chemistry》2011,47(3):417-420
Recyclization of 3-aroyl-1H-pyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones by the action of benzoic acid hydrazides gave N-[2,4-dihydroxy-5-oxo-3-(3-oxo-3,4-dihydroquinoxalin-2-yl)-2-aryl-2,5-dihydro-1H-pyrrol-1-yl]benzamides whose structure was proved by X-ray analysis. 相似文献
12.
A. Yu. Dubovtsev P. S. Silaichev M. A. Zheleznova Z. G. Aliev A. N. Maslivets 《Russian Journal of Organic Chemistry》2016,52(12):1779-1783
Substituted alkyl 4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates reacted with urea to give alkyl 2-(carbamoylamino)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxylates which underwent intramolecular cyclization to 8-hydroxy-1,3,6-triazaspiro[4.4]non-8-ene-2,4,7-triones by the action of sodium methoxide. 相似文献
13.
V. O. Koz’minykh V. I. Goncharov A. V. Aksenov E. N. Koz’minykh K. Sh. Lomidze A. N. Berezin 《Russian Journal of Organic Chemistry》2006,42(9):1356-1359
Methyl and ethyl 2-(2-oxo-2,3-dihydro-3H-indol-3-ylidene)acetates react with aromatic amines to give products of regioselective addition at the α-position of the activated exocyclic C=C bond, methyl and ethyl 2-arylamino-2-(2-oxo-2,3-dihydro-1H-indol-3-yl)acetates. 相似文献
14.
Reactions of methyl acetyl- or benzoylpyruvates with aromatic aldehydes and ethylenediamine, depending on the reactant ratio, afforded 4-acyl-1-(2-aminoethyl)-5-aryl-3-hydroxy-2,5-dihydro-1H-pyrrol-2-ones or 1,2-bis(4-acyl-5-aryl-3-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)ethanes. Substituted 1-(2-aminoethyl)-3-hydroxy-2,5-dihydro-1H-pyrrol-2-one hydrochlorides were brought into reactions with p-methoxyaniline and hydrazine.__________Translated from Zhurnal Obshchei Khimii, Vol. 75, No. 2, 2005, pp. 282–287.Original Russian Text Copyright © 2005 by Gein, Kasimova. 相似文献
15.
Issa Yavari Zinatossadat Hossaini Maryam Sabbaghan Majid Ghazanfarpour-Darjani 《Tetrahedron》2007,63(38):9423-9428
The reaction of ethyl propiolate with triphenylphosphine (Ph3P) in the presence of N-alkylisatins led to ethyl 2,2,2-triphenyl-2,5-dihydro-1,2-λ5-oxaphosphole-4-carboxylate-spiro-1-alkyl-1,3-dihydro-2H-indol-2-ones in good yield. The reaction of dialkyl acetylenedicarboxylates with Ph3P in the presence of N-alkylisatins led to dialkyl 2,2,2-triphenyl-2,5-dihydro-1,2-λ5-oxaphosphole-3,4-dicarboxylate-spiro-1-alkyl-1,3-dihydro-2H-indol-2-ones and alkyl 4-(alkoxy)-5-oxo-2,5-dihydro-3-furancarboxylate-spiro-1-alkyl-1,3-dihydro-2H-indol-2-ones. 相似文献
16.
N. I. Makarova P. V. Levchenko E. N. Shepelenko A. V. Metelitsa V. S. Kozyrev V. P. Rybalkin V. A. Bren?? V. I. Minkin 《Russian Chemical Bulletin》2011,60(9):1899-1905
New nonsymmetric dihetarylethenes were synthesized: 3-(5-methoxy-1,2-dimethyl-1H-indol-3-yl)-4-(3-thienyl)furan-2,5-dione and photochromic 1-alkyl-(1-aryl)-3-(5-methoxy-1,2-dimethyl-1H-indol-3-yl)-4-(3-thienyl)-1(H)-pyrrole-2,5-diones. The absence of benzoannulation in the indole moiety results in the enhancement of the efficiencies of fluorescence and photocyclization of noncyclic isomers compared to the benzoindole derivatives. 相似文献
17.
P. S. Silaichev N. V. Kudrevatykh P. A. Slepukhin A. N. Maslivets 《Russian Journal of Organic Chemistry》2013,49(6):860-863
4,5-Diaroyl-1-aryl-1H-pyrrole-2,3-diones reacted with ethyl 3-amino-3-phenylprop-2-enoate to give ethyl 4-aroyl-1,6-diaryl-3-hydroxy-2-oxo-8-phenyl-1,7-diazaspiro[4.4]nona-3,6,8-triene-9-carboxylates. The crystalline and molecular structures of ethyl 4-benzoyl-3-hydroxy-1-(4-methylphenyl)-2-oxo-6,8-diphenyl-1,7-diazaspiro[4.4]nona-3,6,8-triene-9-carboxylate were determined by X-ray analysis. 相似文献
18.
N. I. Makarova E. N. Shepelenko A. V. Metelitsa V. A. Bren’ V. I. Minkin 《Russian Chemical Bulletin》2013,62(11):2424-2429
Novel asymmetric dihetarylethenes, viz., 3-(1-isopropyl-5-methoxy-2-methyl-1H-indol-3-yl)-4-(3-thienyl)furan-2,5-dione and 1-alkyl/aryl-3-(1-isopropyl-5-methoxy-2-methyl-1H-indol-3-yl)-4-(3-thienyl)-1H-pyrrole-2,5-diones, were obtained. These dihetarylethenes exhibit photochromism in solutions. Replacement of the N-methyl group in the indole fragment by the N-isopropyl group imparts photochromic properties to the resulting furan-2,5-dione derivative. The open forms of (N-isopropylindol-3-yl)pyrrole-2,5-diones are characterized by lower quantum yields of fluorescence, and their cyclic forms are thermally more stable. 相似文献
19.
Saya Kawano Yutaka Yoshikawa Akihiro Kato Shoko Higashi Kyohei Mitani Hiroyuki Yasui Yoichi Habata Shunsuke Kuwahara Kaname Sasaki Ryota Saito 《Tetrahedron letters》2019,60(23):1534-1537
We have developed a synthetic route to novel ethyl 1-arylmethyl-5-oxo-2-thioxopyrrolidine-3-carboxylates (1a–e) via an unprecedented reaction of ethyl 1-arylmethyl-4-acetoxy-5-oxo-2,5-dihydro-1H-pyrrole-3carboxylates with potassium thioacetate. Synthesized products 1a–e were further converted into their zinc(II) complexes (10a–e), having an S2O2-type coordination mode, that showed improved insulin-mimetic activities compared to ZnSO4, a positive standard, and also the previously reported zinc(II) complexes of ethyl 1-benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylates with O4-type coordination mode. 相似文献
20.
4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiols reacted with N-substituted isatins to give 2-oxo-3-[5-(pyridin-4-yl)-3-sulfanyl-4H-1,2,4-triazole-4-ylimino]-2,3-dihydro-1H-indoles which were treated with phenacyl bromides to obtain the corresponding S-phenacyl derivatives. The latter underwent base-catalyzed intramolecular cyclization with formation of 6,7-dihydro-5H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines spiro-fused to 2-oxo-2,3-dihydro-1H-indole fragment at C3. Analogous cyclization of 2,6-di-tert-butyl-4-[5-hetaryl-3-(2-aryl-2-oxoethylsulfanyl)-4H-1,2,4-triazole-4-ylimino]cyclohexa-2,5-dienones involved the imino nitrogen atom to produce the corresponding 6-aroyl-5-(3,5-di-tert-butyl-4-hydroxyphenyl)-3-hetaryl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles. 相似文献