共查询到20条相似文献,搜索用时 15 毫秒
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Zhongjing Huang Changlun Shao Yiguang Chen Zhigang She Yongcheng Lin Shining Zhou 《Chemistry of Natural Compounds》2007,43(6):655-658
A new isocoumarin, 3,4-dihydro-6-methoxy-8-hydroxy-3,4,5-trimethylisocoumarin-7-carboxylic acid methyl ester (1), together with three known compounds, 3,4-dihydro-4,8-dihydroxy-3,5-dimethylisocoumarin (2), 3,4-dihydro-8-hydroxy-3-methylisocoumarin-5-carboxylic acid (3), and Entinclole SB (4) were isolated from the mangrove endophytic fungus (No. dz17). The structure of the compound 1 was elucidated by analysis of spectroscopic data. Primary bioassays showed that 1 exhibited weak cytotoxicity against Hep-2 and HepG2 cells.
Published in Khimiya Prirodnykh Soedinenii, No. 6, pp. 543–545, November–December, 2007. 相似文献
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南海红树内生真菌1947号次级代谢产物的研究 总被引:5,自引:1,他引:4
红树植物是一类生长于潮间带的乔灌木的通称。近年来,国内外对红树内生真菌代谢产物的研究呈快速发展趋势。本课题组自上世纪90年代以来开始研究南海红树内生真菌代谢产物,迄今已从南海红树内生真菌分离得到许多有意义的代谢产物[1-5]。编号为1947号的内生真菌分离自香港江口红 相似文献
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X. K. Xia L. G. Yang Z. G. She C. L. Shao Z. J. Huang F. Liu Y. C. Lin S. N. Zhou 《Chemistry of Natural Compounds》2008,44(4):416-418
Two new acids 1 and 2, together with a known compound, purpactin A (3), were isolated from endophytic fungus No. ZZF13. Their structures were elucidated on the basis of 1D, 2D NMR, and HREIMS
spectra.
Published in Khimiya Prirodnykh Soedinenii, No. 4, pp.336-337, July-August, 2008. Original articlesubmitted April 24, 2007. 相似文献
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Guangying Chen Yongcheng Lin L. L. P. Vrijmoed Wang-Fun Fong 《Chemistry of Natural Compounds》2006,42(2):138-141
A new isochroman, 6-hydroxy-3-methylisochroman-5-carboxylic acid, and six known compounds were isolated from the culture of
marine-derived mangrove fungus 1893#. Their structures were elucidated by analysis of spectroscopic data.
Published in Khimiya Prirodnykh Soedinenii, No. 2, pp. 114–116, March–April, 2006. 相似文献
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Three xanthones were produced from the marine-derived endophytic fungus isolate 1850 from a leaf of Kandelia candel from an
estuarine mangrove in Hong Kong. Their structures were elucidated as sterigmatocystin (1), dihydrosterigmatocystin (2), and secosterigmatocystin (3) by analysis of spectroscopic data.
Published in Khimiya Prirodnykh Soedinenii, No. 2, pp. 111–113, March–April, 2007. 相似文献
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Zhongjing Huang Ruiyun Yang Xianhong Yin Zhigang She Yongcheng Lin 《Magnetic resonance in chemistry : MRC》2010,48(1):80-82
The structure elucidations and complete 1H and 13C NMR assignments are reported for two new xanthone derivatives: 1,7‐dihydroxy‐2‐methoxy‐3‐(3‐methylbut‐2‐enyl)‐9H‐xanthen‐9‐one (1) and 1‐hydroxy‐4,7‐dimethoxy‐6‐(3‐oxobutyl)‐9H‐xanthen‐9‐one (2). Both of these secondary metabolites were isolated from the fermentation medium of a mangrove endophytic fungus (No. ZH19). High‐resolution electron impact mass spectrometry (HREIMS), Fourier transform infrared (FT‐IR) absorption spectrometry, and NMR experiments including gCOSY, gHMQC, and gHMBC were used for the determination of the structures and NMR spectral assignments. Preliminary pharmacological test showed that compounds (1) and (2) inhibited KB cells with IC50 values of 20 and 35 µmol/ml, and KBV200 cells with IC50 values of 30 and 41 µmol/ml, respectively. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
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Jing Li Yanyu Xue Jie Yuan Yongjun Lu Xun Zhu Yongcheng Lin 《Natural product research》2016,30(7):755-760
Four new lasiodiplodins (1–4), together with three known analogues, have been isolated from a mangrove endophytic fungus, Lasiodiplodia sp. 318#. Their structures were elucidated by spectroscopic techniques. Cytotoxic activities of compounds 1–7 were evaluated in vitro against human cancer lines THP1, MDA-MB-435, A549, HepG2 and HCT-116. Compound 4 exhibited moderate cytotoxic activities. 相似文献
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Changlun Shao Changyun Wang Meiyan Wei Zhenbin Jia Zhigang She Yongcheng Lin 《Chemistry of Natural Compounds》2009,45(6):779-781
Two new benzaldehyde derivatives, 6-ethyl-2-hydroxy-4-methoxy-3-methylbenzaldehyde (1), 6-ethyl-2,4-dihydroxy-3-methylbenzaldehyde (2), together with 2, 4-dihydroxy-3,6-dimethylbenzaldehyde (3) were isolated from mangrove fungus (No. ZZF 32#) from the South China Sea. The structures of compounds 1 and 2 were established by comprehensive analysis of the spectral data, especially 2D NMR spectral results. 相似文献
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Shao C Wang C Wei M Gu Y Xia X She Z Lin Y 《Magnetic resonance in chemistry : MRC》2008,46(11):1066-1069
Two new xanthones, 8-(methoxycarbonyl)-1-hydroxy-9-oxo-9H-xanthene-3-carboxylic acid (1) and dimethyl 8-methoxy-9-oxo-9H-xanthene-1,6-dicarboxylate (2) and one known xanthone methyl 8-hydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylate (3) were isolated from the culture broth of the mangrove fungus Penicillium sp. (ZZF 32#) collected from the South China Sea. Their structures were established by comprehensive analysis of one-dimensional (1D) and two-dimensional (2D) NMR data. The structure of compound 3 was confirmed by X-ray crystallography, which led to the suggestion that janthinone (4) might have the same structure as 3. Compounds 1-3 were inactive against KB or KBv200 cells during cytotoxicity evaluations. 相似文献
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W. Y. Shen R. Bai A. R. Wang J. Y. He H. Wang Y. Zhang 《Natural product research》2016,30(19):2173-2182
A highly antagonistic endophytic fungus, designated strain CL39, was originated from the leaves of Chloranthus multistachys collected in Wulong of Chongqing municipality of China in November 2015. The strain was identified as Fusarium solani based on morphological characteristics, 5.8S gene and internal transcribed spacer sequence analysis. Two new compounds, 2β, 9α-dihydroxy-5α-methoxyergosta-7, 22-diene (1), 2β, 6β-dihydroxy-5α-methoxyergosta-7, 22-diene (2) have been isolated from the culture broth of the strain. Structures of the new compounds were elucidated by detailed analysis of their spectroscopic data aided by the comparison with reported data of related derivatives, and found to belong to the polyhydroxylated steroids with a hydroxyl at C-2 instead of C-3, a rare structure among the steroids. The extract of this strain and all isolated compounds were evaluated for their antagonistic activities. 相似文献
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Isolation, structure elucidation, and mutagenicity of four alternariol derivatives produced by the mangrove endophytic fungus No. 2240 总被引:1,自引:0,他引:1
Ni Tan Yiwen Tao Jiahui Pan Sanyong Wang Fang Xu Zhigang She Yongcheng Lin E. B. Gareth Jones 《Chemistry of Natural Compounds》2008,44(3):296-300
A new alternariol derivative, 2240B (1), together with alternariol (2), alternariol 4,10-dimethyl ether (3), and alternariol 4-methyl ether (4), was isolated from the ethyl acetate extract of the liquid medium GYT of No. 2240, the mangrove endophytic fungus from the
South China Sea Coast. The structure of compound 1 was unambiguously elucidated as alternariol 4-methyl-10-acethyl ester by spectra including one/two-dimensional NMR, HREIMS,
IR, and UV. The structures of compounds 2–4 were also established by spectroscopic analyses and comparison with related literature data. The anticancer tests showed
that compounds 2 and 4 had strong activities against KB and KBv200 cells with IC50 values of 3.17, 3.12, and 4.82, 4.94 μg/mL, while compounds 1 and 3 exhibited weak activities against the two kinds of tumor lines with IC50 values of more than 50 μg/mL.
Published in Khimiya Prirodnykh Soedinenii, No. 3, pp. 235–238, May–June, 2008. 相似文献
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Jia-Ting Wu Cai-Juan Zheng Bin Zhang Xue-Ming Zhou Qi Zhou 《Natural product research》2019,33(1):34-40
Two new compounds (1 and 2), together with six known compounds (3–8), were obtained from the Cladosporium sp. JJM22, an endophytic fungus isolated from the stem bark of the mangrove plant Ceriops tagal collected in South China Sea. Their structures were elucidated on the basis of detailed spectroscopic analysis. The absolute configurations of 1 and 2 were confirmed by the comparison of optical rotation and the CD data with those of known compounds. The inhibitory activities of the isolated compounds against six terrestrial pathogenic bacteria and human cervical carcinoma Hela cell line were evaluated. Compound 3 exhibited a broad spectrum of antibacterial activities. 相似文献
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Chunyuan Li Weijiang Ding Zhigang She Yongcheng Lin 《Chemistry of Natural Compounds》2008,44(2):163-165
A new biphenyl derivative 3,5′-dihydroxy-4′,5-dimethoxy-2′-methyl-[1,1′-biphenyl]-2-carboxylic acid methyl ester (1), was isolated from the culture broth of a fungus isolated from the rhizosphere soil of mangrove root on the South China
Sea. The structure of 1 was determined by comprehensive spectroscopic methods, primarily 2D NMR techniques.
Published in Khimiya Prirodnykh Soedinenii, No. 2, pp. 128–129, March–April, 2008. 相似文献
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Liang-Liang Chen Fan-Dong Kong Pei Wang Jing-Zhe Yuan Zhi-Kai Guo Hao Wang Hao-Fu Dai Wen-Li Mei 《中国化学快报》2017,28(2):222-225
Two new tremulane sesquiterpenes coriolopsin A (1) and coriolopsin B (2), together with two known ones conocenol C (3) and ceriponol E (4), were isolated from the fermentation extract of endophytic fungus Coriolopsis sp. J5 from Ceriops tagal. The structures and absolute configuration of compounds 1 and 2 were determined based on HR-ESI-MS and spectroscopic data (IR, UV, 1D, 2D NMR and X-ray crystallographic analysis). 相似文献
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Wenqing Yin Yongcheng Lin Zhigang She L. L. P. Vrijmoed E. B. Gareth Jones 《Chemistry of Natural Compounds》2008,44(1):3-5
A new metabolite xyloketal H (1), was isolated from mangrove fungus Xylaria sp. (No.2508) obtained from the South China Sea. By spectroscopic analyses, primarily 2D NMR methods and X-ray diffraction
experiments, its structure was elucidated.
Published in Khimiya Prirodnykh Soedinenii, No. 1, pp. 5–6, January–February, 2008. 相似文献
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Na Zheng Feihua Yao Xuefeng Liang Quan Liu Weifeng Xu Yan Liang 《Natural product research》2018,32(7):755-760
A new phthalide derivative, xylarphthalide A (1), along with two known compounds (-)-5-carboxylmellein (2) and (-)-5-methylmellein (3), were isolated from the endophytic fungus Xylaria sp. GDG-102 cultured from the Chinese medicinal plant Sophora tonkinensis. Their structures were identified by MS and NMR experiments, and the absolute configuration of 1 was further confirmed by single-crystal X-ray diffraction analysis. Compound 1–3 showed antibacterial activities against Bacillus megaterium, Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Shigella dysenteriae with MIC values of 12.5–25 μg/mL. 相似文献