Structure of a new schiff base cobalt(III) complex with antibacterial activity

A new Schiff base cobalt(III) complex with the formula [CoL¹L²(N₃)]·NO₃ (L¹ is 2-[1-(2-phenylaminoethylimino)ethyl]phenolate, L² is N-phenylethane-1,2-diamine) is prepared and characterized by physicochemical methods and single crystal X-ray determination. The complex crystallizes in the triclinic system space group P-1, with a = 8.504(2) Å, b = 14.973(3) Å, c = 20.676(4) Å, α = 100.021(3)°, β = 90.005(3)°, γ = 103.084(2)°, V = 2523.0(9) ų, Z = 4, R ₁ = 0.0732, and wR ₂ = 0.1182. Single crystal X-ray diffraction analysis reveals that the complex contains two mononuclear [CoL¹L²(N₃)]⁺ cations and two nitrate anions. The Co atom is six-coordinated in an octahedral geometry. The ligands and the cobalt(III) complex are screened in vitro for their antibacterial activity against Bacillus subtillis, Staphylococcus aureus, Escherichia coli, and Pseudomonas aereuguinosa.     

Structure of a diruthenium(II,III) complex with benzamidato bridging ligands

The compound Ru₂Cl(C₆H₅CONH)₄ has now been obtained in crystalline form and the crystal and molecular structure determined by X-ray met     

Dinuclear iron (III) complex with a bridging diphenylphosphate and two terminal diphenylphosphate ligands

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Cyclophosphates as ligands for cobalt(III) in water

Examination of cyclotriphosphate and cyclotetraphosphate as ligands for Co(III) in aqueous solutions revealed that cyclotetraphosphate affords stable complexes as a hemilabile ligand, while cyclotriphosphate exhibits facile hydrolysis.     

Interaction of cobalt(III) polypyridyl complexes containing asymmetric ligands with DNA

Four asymmetric cobalt(III) complexes, [Co(bpy)₂(aip)]³⁺, [Co(bpy)₂(pyip)]³⁺, [Co(phen)₂(aip)]³⁺, and [Co(phen)₂(pyip)]³⁺ (bpy = 2,2,bipyridine, phen = 1,10-phenathroline), (pyip = 2-(1-pyrenyl)-1H-imidazo[4,5-f][phen], (aip = 2-(9-anthryl)-1H-imidazo[4,5,-f][phen], have been synthesized and characterized. Their interaction with calf thymus DNA (CT-DNA) was investigated by physico-chemical methods and photocleavage. The size and shape of the ligands have a marked effect on the DNA-binding affinity of the complexes. Irradiation of pBR322 DNA with these novel cobalt(III) complexes results in nicking of the plasmid DNA. Toxicity and induced cell death investigations revealed that the complexes of pyip had higher toxicity than those of aip. Electronic supplementary material  The online version of this article (doi:) contains supplementary material, which is available to authorized users.     

Tri­azido­cobalt(III) complexes with tridentate amine ligands

The title compounds, [N‐(2‐amino­ethyl)‐1,3‐propane­di­amine‐κ³N]­tri­azido­cobalt(III), [Co(N₃)₃(C₅H₁₅N₃)], [N‐(2‐amino­ethyl)‐N‐methyl‐1,3‐propane­di­amine‐κ³N]­tri­azido­cobalt(III), [Co(N₃)₃(C₆H₁₇N₃)], [N‐(2‐amino­propyl)‐1,3‐pro­pane­di­am­ine‐κ³N]­tri­azido­cobalt(III), [Co(N₃)₃(C₆H₁₇N₃)], and [N‐(2‐amino­propyl)‐N‐methyl‐1,3‐pro­pane­di­am­ine‐κ³N]triazidocobalt(III), [Co(N₃)₃­(C₇­H₁₉­N₃)], each consist of a Co^III atom, three azide ligands in a meridional configuration and a tridentate amine ligand, namely aepn [N‐(2‐amino­ethyl)‐1,3‐propane­di­amine] or dpt [N‐(3‐amino­propyl)‐1,3‐pro­pane­di­amine], or their N‐methyl­­ated analogs.     

Pentadentate terpyridine-catechol linked ligands and their cobalt(III) complexes

A series of novel pentadentate terpyridine-catechol linked ligands were prepared, in which the terpyridine and catechol moieties were linked together by (CH2)n chains of different lengths (n = 4-6). Together with 1-methylimidazole, these ligands formed low-spin, six-coordinate Co(III) complexes. Two of the complexes (n = 4, 5) were characterized by X-ray crystallography [n = 4, monoclinic, P2(1)/c, a = 14.957(7) A, b = 10.585(9) A, c = 23.033(7) A, beta = 106.01(3) degrees, V = 3505(3) A3, Z = 4, R = 0.063; n = 5, monoclinic, P2(1)/c, a = 8.848(7) A, b = 15.78(1) A, c = 25.455(7) A, beta = 93.90(5) degrees, V = 3544(3) A3, Z = 4, R = 0.056], which revealed similar structures around the Co(III) centers but different conformations for the (CH2)n linkers. The (CH2)4 linker showed a straight, symmetric conformation whereas the (CH2)5 linker showed a curved conformation that allowed the accommodation of one extra CH2 unit, suggesting that the (CH2)4 linker presents the "best-fit" length for these complexes.