Analysis of correlated binary data under partially linear single-index logistic models

Clustered data arise commonly in practice and it is often of interest to estimate the mean response parameters as well as the association parameters. However, most research has been directed to address the mean response parameters with the association parameters relegated to a nuisance role. There is relatively little work concerning both the marginal and association structures, especially in the semiparametric framework. In this paper, our interest centers on the inference of both the marginal and association parameters. We develop a semiparametric method for clustered binary data and establish the theoretical results. The proposed methodology is investigated through various numerical studies.     

Efficient estimation in conditional single-index regression

Semiparametric single-index regression involves an unknown finite-dimensional parameter and an unknown (link) function. We consider estimation of the parameter via the pseudo-maximum likelihood method. For this purpose we estimate the conditional density of the response given a candidate index and maximize the obtained likelihood. We show that this technique of adaptation yields an asymptotically efficient estimator: it has minimal variance among all estimators.     

Testing the equality of linear single-index models

Comparison of nonparametric regression models has been extensively discussed in the literature for the one-dimensional covariate case. The comparison problem largely remains open for completely nonparametric models with multi-dimensional covariates. We address this issue under the assumption that models are single-index models (SIMs). We propose a test for checking the equality of the mean functions of two (or more) SIM’s. The asymptotic normality of the test statistic is established and an empirical study is conducted to evaluate the finite-sample performance of the proposed procedure.     

A profile-type smoothed score function for a varying coefficient partially linear model

The varying coefficient partially linear model is considered in this paper. When the plug-in estimators of coefficient functions are used, the resulting smoothing score function becomes biased due to the slow convergence rate of nonparametric estimations. To reduce the bias of the resulting smoothing score function, a profile-type smoothed score function is proposed to draw inferences on the parameters of interest without using the quasi-likelihood framework, the least favorable curve, a higher order kernel or under-smoothing. The resulting profile-type statistic is still asymptotically Chi-squared under some regularity conditions. The results are then used to construct confidence regions for the parameters of interest. A simulation study is carried out to assess the performance of the proposed method and to compare it with the profile least-squares method. A real dataset is analyzed for illustration.     

Model checking in errors-in-variables regression

This paper discusses a class of minimum distance tests for fitting a parametric regression model to a class of regression functions in the errors-in-variables model. These tests are based on certain minimized distances between a nonparametric regression function estimator and a deconvolution kernel estimator of the conditional expectation of the parametric model being fitted. The paper establishes the asymptotic normality of the proposed test statistics under the null hypothesis and that of the corresponding minimum distance estimators. We also prove the consistency of the proposed tests against a fixed alternative and obtain the asymptotic distributions for general local alternatives. Simulation studies show that the testing procedures are quite satisfactory in the preservation of the finite sample level and in terms of a power comparison.     

Functional-coefficient partially linear regression model

In this paper, the functional-coefficient partially linear regression (FCPLR) model is proposed by combining nonparametric and functional-coefficient regression (FCR) model. It includes the FCR model and the nonparametric regression (NPR) model as its special cases. It is also a generalization of the partially linear regression (PLR) model obtained by replacing the parameters in the PLR model with some functions of the covariates. The local linear technique and the integrated method are employed to give initial estimators of all functions in the FCPLR model. These initial estimators are asymptotically normal. The initial estimator of the constant part function shares the same bias as the local linear estimator of this function in the univariate nonparametric model, but the variance of the former is bigger than that of the latter. Similarly, initial estimators of every coefficient function share the same bias as the local linear estimates in the univariate FCR model, but the variance of the former is bigger than that of the latter. To decrease the variance of the initial estimates, a one-step back-fitting technique is used to obtain the improved estimators of all functions. The improved estimator of the constant part function has the same asymptotic normality property as the local linear nonparametric regression for univariate data. The improved estimators of the coefficient functions have the same asymptotic normality properties as the local linear estimates in FCR model. The bandwidths and the smoothing variables are selected by a data-driven method. Both simulated and real data examples related to nonlinear time series modeling are used to illustrate the applications of the FCPLR model.     

Statistical inference for the index parameter in single-index models

In this paper, we are concerned with statistical inference for the index parameter in the single-index model . Based on the estimates obtained by the local linear method, we extend the generalized likelihood ratio test to the single-index model. We investigate the asymptotic behaviour of the proposed test and demonstrate that its limiting null distribution follows a χ²-distribution, with the scale constant and the number of degrees of freedom being independent of nuisance parameters or functions, which is called the Wilks phenomenon. A simulated example is used to illustrate the performance of the testing approach.     

A lack-of-fit test in Tobit errors-in-variables regression models

The problem of fitting a parametric model in Tobit errors-in-variables regression models is discussed in this paper. The proposed test is based on the supremum of the Khmaladze type transformation of a certain partial sum process of calibrated residuals. This framework covers the usual error-free Tobit model as a special case. The asymptotic null distribution of this transformed process is shown to be the same as that of a time transformed standard Brownian motion. Consistency against some fixed alternatives and asymptotic power under some local nonparametric alternatives of this test are also discussed. Simulation studies are conducted to assess the finite sample performance of the proposed test.     

Empirical likelihood for a varying coefficient partially linear model with diverging number of parameters

The purpose of this paper is two-fold. First, for the estimation or inference about the parameters of interest in semiparametric models, the commonly used plug-in estimation for infinite-dimensional nuisance parameter creates non-negligible bias, and the least favorable curve or under-smoothing is popularly employed for bias reduction in the literature. To avoid such strong structure assumptions on the models and inconvenience of estimation implementation, for the diverging number of parameters in a varying coefficient partially linear model, we adopt a bias-corrected empirical likelihood (BCEL) in this paper. This method results in the distribution of the empirical likelihood ratio to be asymptotically tractable. It can then be directly applied to construct confidence region for the parameters of interest. Second, different from all existing methods that impose strong conditions to ensure consistency of estimation when diverging the number of the parameters goes to infinity as the sample size goes to infinity, we provide techniques to show that, other than the usual regularity conditions, the consistency holds under moment conditions alone on the covariates and error with a diverging rate being even faster than those in the literature. A simulation study is carried out to assess the performance of the proposed method and to compare it with the profile least squares method. A real dataset is analyzed for illustration.     

Empirical likelihood inference in partially linear single-index models for longitudinal data

The empirical likelihood method is especially useful for constructing confidence intervals or regions of parameters of interest. Yet, the technique cannot be directly applied to partially linear single-index models for longitudinal data due to the within-subject correlation. In this paper, a bias-corrected block empirical likelihood (BCBEL) method is suggested to study the models by accounting for the within-subject correlation. BCBEL shares some desired features: unlike any normal approximation based method for confidence region, the estimation of parameters with the iterative algorithm is avoided and a consistent estimator of the asymptotic covariance matrix is not needed. Because of bias correction, the BCBEL ratio is asymptotically chi-squared, and hence it can be directly used to construct confidence regions of the parameters without any extra Monte Carlo approximation that is needed when bias correction is not applied. The proposed method can naturally be applied to deal with pure single-index models and partially linear models for longitudinal data. Some simulation studies are carried out and an example in epidemiology is given for illustration.     

Statistical inference for panel data semiparametric partially linear regression models with heteroscedastic errors

We consider a panel data semiparametric partially linear regression model with an unknown parameter vector for the linear parametric component, an unknown nonparametric function for the nonlinear component, and a one-way error component structure which allows unequal error variances (referred to as heteroscedasticity). We develop procedures to detect heteroscedasticity and one-way error component structure, and propose a weighted semiparametric least squares estimator (WSLSE) of the parametric component in the presence of heteroscedasticity and/or one-way error component structure. This WSLSE is asymptotically more efficient than the usual semiparametric least squares estimator considered in the literature. The asymptotic properties of the WSLSE are derived. The nonparametric component of the model is estimated by the local polynomial method. Some simulations are conducted to demonstrate the finite sample performances of the proposed testing and estimation procedures. An example of application on a set of panel data of medical expenditures in Australia is also illustrated.     

Corrected empirical likelihood inference for right-censored partially linear single-index model

This article deals with the inference on a right-censored partially linear single-index model (RCPLSIM). The main focus is the local empirical likelihood-based inference on the nonparametric part in RCPLSIM. With a synthetic data approach, an empirical log-likelihood ratio statistic for the nonparametric part is defined and it is shown that its limiting distribution is not a central chi-squared distribution. To increase the accuracy of the confidence interval, we also propose a corrected empirical log-likelihood ratio statistic for the nonparametric function. The resulting statistic is proved to follow a standard chi-squared limiting distribution. Simulation studies are undertaken to assess the finite sample performance of the proposed confidence intervals. A real example is also considered.     

Generalized partially linear models with missing covariates

In this article we study a semiparametric generalized partially linear model when the covariates are missing at random. We propose combining local linear regression with the local quasilikelihood technique and weighted estimating equation to estimate the parameters and nonparameters when the missing probability is known or unknown. We establish normality of the estimators of the parameter and asymptotic expansion for the estimators of the nonparametric part. We apply the proposed models and methods to a study of the relation between virologic and immunologic responses in AIDS clinical trials, in which virologic response is classified into binary variables. We also give simulation results to illustrate our approach.     

Structural test in regression on functional variables

Many papers deal with structural testing procedures in multivariate regression. More recently, various estimators have been proposed for regression models involving functional explanatory variables. Thanks to these new estimators, we propose a theoretical framework for structural testing procedures adapted to functional regression. The procedures introduced in this paper are innovative and make the link between former works on functional regression and others on structural testing procedures in multivariate regression. We prove asymptotic properties of the level and the power of our procedures under general assumptions that cover a large scope of possible applications: tests for no effect, linearity, dimension reduction, …     

On rates of convergence in functional linear regression

This paper investigates the rate of convergence of estimating the regression weight function in a functional linear regression model. It is assumed that the predictor as well as the weight function are smooth and periodic in the sense that the derivatives are equal at the boundary points. Assuming that the functional data are observed at discrete points with measurement error, the complex Fourier basis is adopted in estimating the true data and the regression weight function based on the penalized least-squares criterion. The rate of convergence is then derived for both estimators. A simulation study is also provided to illustrate the numerical performance of our approach, and to make a comparison with the principal component regression approach.     

Thresholding projection estimators in functional linear models

We consider the problem of estimating the regression function in functional linear regression models by proposing a new type of projection estimators which combine dimension reduction and thresholding. The introduction of a threshold rule allows us to get consistency under broad assumptions as well as minimax rates of convergence under additional regularity hypotheses. We also consider the particular case of Sobolev spaces generated by the trigonometric basis which permits us to get easily mean squared error of prediction as well as estimators of the derivatives of the regression function. We prove that these estimators are minimax and rates of convergence are given for some particular cases.     

Rank-based inference for the single-index model

This paper is concerned with estimating the coefficients in single-index models. We develop a robust estimator, which combines the ideas of rank-based regression inference and outer product of gradients. Both asymptotic and numerical results show that the proposed procedure has better performance than the least-squares-based method when the errors deviate from normal.     

Estimation of the regression operator from functional fixed-design with correlated errors

We consider the estimation of the regression operator r in the functional model: Y=r(x)+ε, where the explanatory variable x is of functional fixed-design type, the response Y is a real random variable and the error process ε is a second order stationary process. We construct the kernel type estimate of r from functional data curves and correlated errors. Then we study their performances in terms of the mean square convergence and the convergence in probability. In particular, we consider the cases of short and long range error processes. When the errors are negatively correlated or come from a short memory process, the asymptotic normality of this estimate is derived. Finally, some simulation studies are conducted for a fractional autoregressive integrated moving average and for an Ornstein-Uhlenbeck error processes.     

Empirical likelihood for semiparametric regression model with missing response data

A bias-corrected technique for constructing the empirical likelihood ratio is used to study a semiparametric regression model with missing response data. We are interested in inference for the regression coefficients, the baseline function and the response mean. A class of empirical likelihood ratio functions for the parameters of interest is defined so that undersmoothing for estimating the baseline function is avoided. The existing data-driven algorithm is also valid for selecting an optimal bandwidth. Our approach is to directly calibrate the empirical log-likelihood ratio so that the resulting ratio is asymptotically chi-squared. Also, a class of estimators for the parameters of interest is constructed, their asymptotic distributions are obtained, and consistent estimators of asymptotic bias and variance are provided. Our results can be used to construct confidence intervals and bands for the parameters of interest. A simulation study is undertaken to compare the empirical likelihood with the normal approximation-based method in terms of coverage accuracies and average lengths of confidence intervals. An example for an AIDS clinical trial data set is used for illustrating our methods.