Synthesis, Structure and Magnetic Properties of a Diphenoxo-bridged Binuclear Copper(II) Complex

ＩｎｔｒｏｄｕｃｔｉｏｎＥｘｃｈａｎｇｅ ｃｏｕｐｌｅｄｐｏｌｙｎｕｃｌｅａｒｃｏｐｐｅｒ(ＩＩ)ｃｏｍｐｌｅｘ ｅｓａｒｅｏｆｓｐｅｃｉａｌｉｎｔｅｒｅｓｔｄｕｅｔｏｔｈｅｉｒｉｎｖｏｌｖｅｍｅｎｔｉｎｂｉｏ ｌｏｇｉｃａｌｐｒｏｃｅｓｓｅｓａｎｄｉｎｉｎｏｒｇａｎｉｃｍａｔｅｒｉａｌｓ .1,2 Ｔｈｅｉｎｔｉ ｍａｔｅｒｅｌａｔｉｏｎｓｈｉｐｂｅｔｗｅｅｎｔｈｅｓｐｉｎｃｏｕｐｌｉｎｇａｎｄｔｈｅｍｏｌｅｃｕｌａｒｓｔｒｕｃｔｕｒｅｈａｓｆｏｓｔｅｒｅｄｔｈｅｅｍｅｒｇｅｎｃｅｏｆｍｏｌｅｃ ｕｌａｒ…     

Synthesis,Structure and Magnitic Properties of a Diphenoxobridged Binuclear Copper（Ⅲ） Complex

A mixed-ligand copper(Ⅱ） complex[Cu2(phen)2(HL^1)2]-(ClO4)2(1) was synthesized.X-ray analyses reveal that 1 has a bis(μ2-phenoxo)-bridged dicopper(Ⅱ） structure.2D hydrogen-bonded network is formed utilizing the N-H,O-H and C-H groups of the (HL^1) ligands (H2L^1=N-(2-hydroxybenzyl)ethanolamine),the C-H groups of the phenanthrolines and the perchlorate anions.Variable temperature magnetic properties of 1 have shown comparatively weak antiferromagnetic interactions with respect to the bridge angles, which have been ascribed to the unfavorable overlaps of the magnetic orbitals fo the highly distorted copper coordination polyhedra and the pyramidal distortions at the phenoxo oxygen atoms.     

Synthesis and Crystal Structure of Binuclear Copper （Ⅱ） Complex Containing （Dimethylaminomethyl）ferrocene

1 INTRODUCTION Transition metal complexes with ferrocene are of considerable interest in the past fifty years because of their novel structures and special properties[1, 2]. The chemistry of ferrocene and its derivatives has become richer and richer in the last decade. Many complexes containing ferrocenyl have been synthesized and characterized[3～5]. Recently we have reported the synthesis and crystal structure of dibromo[1,1?bis(diphenylphosphino)- ferrocene]cadmium (Ⅱ)[6]. Herein we…     

Synthesis and Crystal Structure of a Copper(II) Complex with Benzilic Acid and 1,10-Phenanthroline

A new complex [Cu(phen)3][(C6H5)2C(OH)COO]2·6H2O was prepared by self-assembly of benzilic acid, 1,10-phenanthroline (phen), and copper perchlorate. It crystallizes in triclinic, space group P1, with a = 1.14661(17), b = 1.6455(2), c = 1.6457(2) nm, α = 74.779(2), β = 74.904(3), γ = 84.424(3)o, V = 2.8914(7) nm3, Dc = 1.340 g/cm3, Z = 2, F(000) = 1218, GOOF = 1.018, the final R = 0.0643 and wR = 0.1633. The crystal structure shows that the copper ion is coordinated with six nitrogen atoms from six 1,10-phenanthroline molecules, forming a distorted octahedral coordination geometry.     

Synthesis and Crystal Structure of Binuclear Complex of Copper(Ⅱ)Chloroacetate with Acetamine

１ＩＮＴＲＯＤＵＣＴＩＯＮＣｏｐｐｅｒｃｏｍｐｌｅｘｅｓｈａｖｅａｌａｒｇｅｖａｒｉｅｔｙｏｆｓｔｅｒｉｃｓｔｒｕｃｔｕｒｅｓａｎｄｐｌａｙａｎｉｍｐｏｒｔａｎｔｒｏｌｅｉｎｃａｔａｌｙｓｉｎｇｔｈｅｅｎｚｙｍａｔｉｃａｃｔｉｖｉｔｉｅｓ，ｗｈｉｃｈ...     

双核Cu(II)-牛磺酸缩水杨醛席夫碱配合物的合成、晶体结构及生物活性

合成了双核铜配合物 [Cu(TSSB) (H2 O) ] 2 ·2H2 O (TSSB =牛磺酸缩水杨醛席夫碱 ) ,通过元素分析、红外光谱对配合物进行了表征 ,并利用X射线法测定其结构 .晶体属三斜晶系 ,空间群P1- ,其晶胞参数为 :a =0 .69613 ( 19)nm ,b =0 .93 0 7( 3 )nm ,c=1.0 43 9( 3 )nm ;α =10 8.796( 5 )° ,β =10 1.2 71( 5 )° ,γ =10 5 .617( 5 )° ,V =0 .5 869( 3 )nm3 ,Z =1,Dcald=1.849g/cm3 ,μ =2 .0 5 8mm-1,F( 0 0 0 ) =3 3 4,Gof =1.0 79,Δρ =3 79～ -4 0 6e·nm-3 .两个铜原子配位数各为五 ,处于变形四方锥的配位环境中 .并对配合物进行了的生物活性试验 ,结果表明 ,配合物抗菌活性与青霉素接近 ,肿瘤抑制率达 63 .5 % .半数致死量为 10 0 0mg/kg .有可能成为一种新的抗菌、抗肿瘤药物     

Synthesis and Crystal Structure of Copper(II) Complex with N-Acetoxyl-picolinamide

1 INTRODUCTION The picoloylhydrazide compounds are close to thebiologic environment and can react with microele-ments in organism so as to have antitubercular andantineoplastic activities. However, owing to the exis-tence of amino group, this kind of compounds aretoxic to some extent[1]. In order to decrease theirtoxicity, hydrazone or hydrazide compounds synthe-sized by the condensation reaction of amino and car-bonyl groups have been well studied in recentyears[1～7]. Herein we report t…     

钒氧多酸桥联大环铜配合物的合成及其晶体结构

以大环铜配合物［CuL］(ClO₄)₂(L=5,7,7,12,14,14-六甲基-1,4,8,11-四氮杂环十四-4,11-二烯)与NH₄VO₃反应合成了一个新的钒氧多酸桥联大环铜配合物［CuL］₂［H₂V₁₀O₂₈］·7H₂O(1),其结构经IR,元素分析和X-射线单晶衍射表征。1（CCDC: 1510831）属单斜晶系,P2(1)/n空间群,晶胞参数a=11.512(3) , b=18.170(4) , c=14.534(3) , β=102.997(4)°, V=2 962.3(11) ³, Dc=1.986 mg·cm^-3, Z=2, μ=2.300 mm^-1, R₁=0.047 2, wR₂=0.118 2。     

9-羟基-芴-9-羧酸双核铜配合物[Cu(C_(14)H_8O_3)(C_9H_7N)(C_2H_5OH)]_2的合成、晶体结构及热稳定性研究

在自然界中,α-羟基羧酸广泛的存在于动植物体内,在羧酸循环、碳水化合物代谢和氨基酸的合成中起到重要的作用。Tapscott等详细总结了有关羟基羧酸及其金属配合物的合成化学[1]。芴的9位上2个氢原子被羟基和羧基取代可生成9-羟基-芴-9-羧酸(简称芴酸),它是α-羟基乙酸的衍生物,是一种具有生理活性的植物生长整形素,它能够延缓植株生长,影响植株根的向地性和茎的向光性[2]。由于芴酸含有羟基和羧基两种不同的氧配位原子,使其又可以作为一种潜在的构筑配合物的组织基元。目前有关芴酸与金属离子的合成与结构化学研究相对较少,仅见铜、镉的单…     

Synthesis and Characterization of an Unexpected Asymmetric Binuclear Copper(I) Complex Containing 4-Vinyl-pyridine

Introduction Many examples of complexes containing the eight-membered ring M(-dppm)M' are known with a variety of metals, oxidation states and stereochemis-tries.1-4 In general, they contain trans-bound, bridging dppm ligands to give a planar M2P4 core structure with the two metal atoms held in close proximity to each other (regardless of whether a metal-metal bond is pre-sent or not). This feature is presumably one of the chief reasons for the unusual bonding, reactivity and catalytic prope…     

5-溴水杨醛缩乙醇胺Schiff碱Cu(II)配合物的合成和晶体结构

The title complex Cu(L)₂ [HL=N-(5-bromosalicylidene)-2-aminoethanol] was synthesized by the reaction of Cu(CH₃COO)₂·H₂O with N-(5-bromosalicylidene)-2-aminoethanol in the ethanol. It was characterized by elemental analysis, IR and X-ray single crystal diffraction analysis. The crystal of the title complex [Cu(C₉H₉BrNO₂)₂] belongs to monoclinic, space group P2₁/n with a=1.319 1(5) nm, b=0.444 58(16) nm, c=1.656 7(6) nm, β=91.226(5)°, V=0.971 46(6) nm³, Z=2, D_c=1.879 Mg·m^-3, μ=5.264 mm^-1, F(000)=542, and final R₁=0.045 6, wR₂=0.097 0. The complex comprises a four-coordinated copper(II) center, with an N₂O₂ planar coordination environment. The molecules are connected by hydrogen bonds to form two-dimensional layered structure. CCDC: 274180.     

Synthesis and Crystal Structure of a Copper(II) Complex with 2,4-Dihydroxybenzylidene Benzoylhydrazone Ligand

1 INTRODUCTION The chemical properties of acylhydrazones Schiff bases and their complexes with some transition metal ions have been intensively investigated in several re- search areas because of their chelating capability and pharmacological applications[1～10]. Intriguingly, the copper(II) complexes are shown to be signifycantly more potent than the metal free chelate, suggesting that the metal complex is the biologically active species. Owing to the biological interest in these types …     

Synthesis,Structure and Fluorescence of a Copper(II) Complex [Cu_2(bipy)_2(Hpht)_2Cl](Hpht)(bipy=2,2'-Bipyridine,H_2pht=o-Phthalic Acid)

1 INTRODUCTION o-Phthalic acid (H2pht) is a versatile ligand for co-ordinating to metal ions in various modes, such asmonodentate bonding through a carboxylic O atom[1],bidentate fashion via two carboxylic O atoms[2] andtriple coordination through its three carboxylic Oatoms[3], and bridging mode with two or four Oatoms of its carboxylate groups[4]. The coordinationproperties thus allow for the preparation of complex-es with a large variety of architectures, forming iso-lated mono-, di…     

Synthesis and Crystal Structure of the Copper(II) Complex with N,N'-Cyclohexanebis(3- formyl- 5-tert-butyl-salicylaldimine)

INTRODUCTION Schiff-base complexes are some of the most important stereochemical models in transition metal coordination chemistry, with their ease of preparation and structural variation.[1~4] Metal derivatives of Schiff-base have been studied extensively, and copper(II) and nickel (II) complexes play major roles in both synthetic and structural research. The geometry of the coordination sphere is usually planar in the case of Ni, but of Cu, a tetrahedral distortion is often observed.[…     

含氟喹诺酮双核铜(Ⅱ)配合物的合成、晶体结构和生物活性

A new binuclear copper(Ⅱ) complex containing fluoroquinolone ligand， [Cu₂(cfc)₂(bpy)₂(pip)]·6H₂O， was synthesized and its crystal structure was solved. The formula of the complex is C₂₅H₂₆ClCuFN₄O₆， and the crystal-lography data are as follows， triclinic， space group P1， a=6.874(2)?， b=10.761(3)?， c=17.976(5)?， α=80.071(6)°， β=85.253(6)°， γ=79.109(6)°， V=1284.5(6)?3， D=1.542g·cm^-3， F(000)=614， and Z=2. R₁=0.0776 and wR₂=0.2235(I >2σ(I)). The copper atom is five-coordinate with square-based pyramidal geometry and involves two nitrogen atoms from bpy， two oxygen atoms from cfc and one nitrogen atom from pip anion. The stacking effect between cfc and bpy ligands from two neighboring molecules was observed. Both ligand and complex were assayed against gram-positive and gram-negative bacteria by doubling dilutions method， the complex shows the same minimal inhibitory concentration (MIC) as the corresponding ligand against S.Aureus and E.Coli bacteria. The inhibitory effect of the ligand and complex on leukemia HL-60 cell line and liver cancer BEL-7402 cell line have been measured by using MTT (Methyl-Thiazol- Tetrozolium) and SRB (Sulphurhodamin B) assay methods. The results indicated that the complex has strong inhibitory effect on HL-60 cell line and on BEL-7402 cell line. CCDC： 191087.     

双大环配体与铜双核配合物的合成、晶体结构和磁偶合性质

由新型双功能配体2,6-双(1,5,9-三氮杂环十二烷)-2,6-二甲基苯甲酸(L)与溴化铜在甲醇中反应得到新型铜双核配合物[Cu~2LBr~2]Br.3H~2O单晶。晶体结构分析表明:2个Cu(II)中心离子由配体L中的羧酸基团桥联;2个等价的Cu(II)中心离子均由双功能配体L的1,5,9-三氮杂环十二烷([12aneN~3)的3个氮原子和羧酸的1个氧原子及1个Br^-离子配位,并都处在三角双锥的配位环境中;分子内Cu...Cu双核间的距离为0.5884(6)nm。变温磁化率数据表明:在同一分子中的2个铜核之间存在反铁磁偶合作用(J=-22.49cm^-^1)。     

含取代芳酰腙和单齿N-杂环分子铜(II)配合物的合成、结构及荧光性质

合成了1个含有取代芳酰腙和单齿N-杂环分子的三元铜配合物[Cu(L)(ampy)](H₂L=5-溴水杨醛苯甲酰腙，ampy=2-氨基吡啶)，并通过IR、UV、荧光光谱和循环伏安进行了性质研究。[Cu(L)(ampy)]的晶体结构分析表明，中心金属通过酰腙配体的酚基氧原子、亚胺基氮原子、去质子酰胺氧原子以及中性杂环分子的氮原子形成平面四方形的N₂O₂配位环境。配合物通过N-H…O和N-H…N氢键作用形成一维链状结构。     

一维链状镉配合物的合成及结构表征

在甲醇体系中合成了镉配合物[Cd(L)₂(H₂O)₂](ClO₄)₂·MeOH (1)[L=1,3,5-三(3-吡啶基甲氧基)苯]。通过元素分析及X-射线单晶衍射对其进行了表征。结构分析结果表明该化合物属于三斜晶系,P1空间群,晶胞参数为a=1.057 1(5) nm,b=1.059 0(5) nm,c=1.270 8(7) nm,α=87.460(16)°,β=81.895(17)°,γ=62.326(14)°,晶胞体积V=1.247 0(11) nm³,Z=1,D_calc=1.569 g·cm^-3,F(000)=604,μ=6.26 cm^-1,R=0.035 2,wR=0.066 4。在化合物1中,每个Cd(II)的配位环境为变形八面体,而每个配体L通过其两个吡啶基团连接2个Cd(II)形成一维链状结构,并进一步通过O-H…N,O-H…O和C-H…O氢键作用形成了一个具有三维结构的超分子化合物。     

β-二酮双核铜(Ⅰ)配合物的合成与结构

室温下,通过双二苯基膦甲烷还原[Cu(tfac)     

Synthesis and Crystal Structure of the Copper(II) Complex with Tris-(1,10-phenanthroline-5,6-dione)

1　ＩＮＴＲＯＤＵＣＴＩＯＮ1 ,1 0 Ｐｈｅｎａｎｔｈｒｏｌｉｎｅ 5,6 ｄｉｏｎｅ (Ｌ)ｃａｒｒｉｅｓａｎｏ ｑｕｉｎｏｎｅｍｏｉｅｔｙｗｉｔｈｐＨ ｄｅｐｅｎ ｄｅｎｔｅｌｅｃｔｒｏａｃｔｉｖｉｔｙａｎｄｃａｎｆｏｒｍｓｔａｂｌｅｃｏｍｐｌｅｘｅｓｗｉｔｈａｗｉｄｅｖａｒｉｅｔｙｏｆｍｅｔａｌｉｏｎｓ,ａｎｄｔｈｅｓｏｌｕｔｉｏｎｃｈｅｍｉｓｔｒｙａｎｄｅｌｅｃｔｒｏｃｈｅｍｉｓｔｒｙｏｆｉｔｓｔｒａｎｓｉｔｉｏｎｍｅｔａｌｃｏｍｐｌｅｘｅｓｈａｖｅｂｅｅｎｅｘｔｅｎｓｉｖｅｌｙｓｔｕｄｉｅｄ[1,2 ].Ｈ…