Model checking for partially linear models with missing responses at random

In this paper, we investigate the model checking problem for a partial linear model while some responses are missing at random. By imputation and marginal inverse probability weighted methods, two completed data sets are constructed. Based on the two completed data sets, we build two empirical process-based tests for examining the adequacy of partial linearity of the model. The asymptotic distributions of the test statistics under the null hypothesis and local alternative hypotheses are obtained respectively. A re-sampling approach is applied to obtain the approximation to the null distributions of the test statistics. Simulation results show that the proposed tests work well and both proposed methods have better finite sample properties compared with the complete case (CC) analysis which discards all the subjects with missing data.     

Estimation in partially linear models with missing responses at random

A partially linear model is considered when the responses are missing at random. Imputation, semiparametric regression surrogate and inverse marginal probability weighted approaches are developed to estimate the regression coefficients and the nonparametric function, respectively. All the proposed estimators for the regression coefficients are shown to be asymptotically normal, and the estimators for the nonparametric function are proved to converge at an optimal rate. A simulation study is conducted to compare the finite sample behavior of the proposed estimators.     

Partially linear varying coefficient models with missing at random responses

This paper considers partially linear varying coefficient models when the response variable is missing at random. The paper uses imputation techniques to develop an omnibus specification test. The test is based on a simple modification of a Cramer von Mises functional that overcomes the curse of dimensionality often associated with the standard Cramer von Mises functional. The paper also considers estimation of the mean functional under the missing at random assumption. The proposed estimator lies in between a fully nonparametric and a parametric one and can be used, for example, to obtain a novel estimator for the average treatment effect parameter. Monte Carlo simulations show that the proposed estimator and test statistic have good finite sample properties. An empirical application illustrates the applicability of the results of the paper.     

Empirical likelihood for single-index models with responses missing at random

The missing response problem in single-index models is studied, and a bias-correction method to infer the index coefficients is developed. Two weighted empirical log-likelihood ratios with asymptotic chisquare are derived, and the corresponding empirical likelihood confidence regions for the index coefficients are constructed. In addition, the estimators of the index coefficients and the link function are defined, and their asymptotic normalities are proved. A simulation study is conducted to compare the empirical likelihood and the normal approximation based method in terms of coverage probabilities and average lengths of confidence intervals. A real example illustrates our methods.     

Empirical likelihood for linear models with missing responses

The purpose of this article is to use an empirical likelihood method to study the construction of confidence intervals and regions for the parameters of interest in linear regression models with missing response data. A class of empirical likelihood ratios for the parameters of interest are defined such that any of our class of ratios is asymptotically chi-squared. Our approach is to directly calibrate the empirical log-likelihood ratio, and does not need multiplication by an adjustment factor for the original ratio. Also, a class of estimators for the parameters of interest is constructed, and the asymptotic distributions of the proposed estimators are obtained. Our results can be used directly to construct confidence intervals and regions for the parameters of interest. A simulation study indicates that the proposed methods are comparable in terms of coverage probabilities and average lengths/areas of confidence intervals/regions. An example of a real data set is used for illustrating our methods.     

Variable selection for semiparametric varying-coefficient partially linear models with missing response at random

In this paper, we present a variable selection procedure by combining basis function approximations with penalized estimating equations for semiparametric varying-coefficient partially linear models with missing response at random. The proposed procedure simultaneously selects significant variables in parametric components and nonparametric components. With appropriate selection of the tuning parameters, we establish the consistency of the variable selection procedure and the convergence rate of the regularized estimators. A simulation study is undertaken to assess the finite sample performance of the proposed variable selection procedure.     

Statistical estimation in partial linear models with covariate data missing at random

In this paper, we consider the partial linear model with the covariables missing at random. A model calibration approach and a weighting approach are developed to define the estimators of the parametric and nonparametric parts in the partial linear model, respectively. It is shown that the estimators for the parametric part are asymptotically normal and the estimators of g(·) converge to g(·) with an optimal convergent rate. Also, a comparison between the proposed estimators and the complete case estimator is made. A simulation study is conducted to compare the finite sample behaviors of these estimators based on bias and standard error.     

Checking the adequacy of partial linear models with missing covariates at random

In this paper, we consider the goodness-of-fit for checking whether the nonparametric function in a partial linear regression model with missing covariate at random is a parametric one or not. We estimate the selection probability by using parametric and nonparametric approaches. Two score type tests are constructed with the estimated selection probability. The asymptotic distributions of the test statistics are investigated under the null and local alterative hypothesis. Simulation studies are carried out to examine the finite sample performance of the sizes and powers of the tests. We apply the proposed procedure to a data set on the AIDS clinical trial group (ACTG 315) study.     

Model averaging for semiparametric additive partial linear models

To improve the prediction accuracy of semiparametric additive partial linear models(APLM) and the coverage probability of confidence intervals of the parameters of interest,we explore a focused information criterion for model selection among ALPM after we estimate the nonparametric functions by the polynomial spline smoothing,and introduce a general model average estimator.The major advantage of the proposed procedures is that iterative backfitting implementation is avoided,which thus results in gains in co...     

Estimation for partially linear models with missing responses: the fixed design case

Suppose that we have a partially linear model Yi=x′iβ+g(ti)+εi with independent zero mean errorsεi,where{xi,ti,i=1,···,n}are non-random and observed completely and{Yi,i=1,···,n}are missing at random(MAR).Two types of estimators ofβand g(t)for fixed t are investigated:estimators based on semiparametric regression and inverse probability weighted imputations.Asymptotic normality of the estimators is established,which is used to construct normal approximation based confidence intervals onβand g(t).Results are reported of a simulation study on the finite sample performance of the estimators and confidence intervals proposed in this paper.     

Frequentist model averaging for linear mixed-effects models

Linear mixed-effects models are a powerful tool for the analysis of longitudinal data. The aim of this paper is to study model averaging for linear mixed-effects models. The asymptotic distribution of the frequentist model average estimator is derived, and a confidence interval procedure with an actual coverage probability that tends to the nominal level in large samples is developed. The two confidence intervals based on the model averaging and based on the full model are shown to be asymptotically equivalent. A simulation study shows good finite sample performance of the model average estimators.     

Empirical likelihood semiparametric nonlinear regression analysis for longitudinal data with responses missing at random

This paper develops the empirical likelihood (EL) inference on parameters and baseline function in a semiparametric nonlinear regression model for longitudinal data in the presence of missing response variables. We propose two EL-based ratio statistics for regression coefficients by introducing the working covariance matrix and a residual-adjusted EL ratio statistic for baseline function. We establish asymptotic properties of the EL estimators for regression coefficients and baseline function. Simulation studies are used to investigate the finite sample performance of our proposed EL methodologies. An AIDS clinical trial data set is used to illustrate our proposed methodologies.     

Empirical likelihood inference for a partially linear errors-in-variables model with covariate data missing at random

The authors study the empirical likelihood method for partially linear errors-in-variablesmodel with covariate data missing at random. Empirical likelihood ratios for the regression coefficients and the baseline function are investigated, and the corresponding empirical log-likelihood ratios are proved to be asymptotically standard chi-squared, which can be used to construct confidence regions. The finite sample behavior of the proposed methods is evaluated by a simulation study which indicates that the proposed methods are comparable in terms of coverage probabilities and average length of confidence intervals. Finally, the Earthquake Magnitude dataset is used to illustrate our proposed method.     

Generalized partially linear models with missing covariates

In this article we study a semiparametric generalized partially linear model when the covariates are missing at random. We propose combining local linear regression with the local quasilikelihood technique and weighted estimating equation to estimate the parameters and nonparameters when the missing probability is known or unknown. We establish normality of the estimators of the parameter and asymptotic expansion for the estimators of the nonparametric part. We apply the proposed models and methods to a study of the relation between virologic and immunologic responses in AIDS clinical trials, in which virologic response is classified into binary variables. We also give simulation results to illustrate our approach.     

A class of weighted estimating equations for additive hazard models with covariates missing at random

Missing covariate data arise frequently in biomedical studies. In this article, we propose a class of weighted estimating equations for the additive hazard regression model when some of the covariates are missing at random. Time-specific and subject-specific weights are incorporated into the formulation of weighted estimating equations. Unified results are established for estimating selection probabilities that cover both parametric and non-parametric modeling schemes. The resulting estimators have closed forms and are shown to be consistent and asymptotically normal. Simulation studies indicate that the proposed estimators perform well for practical settings. An application to a mouse leukemia study is illustrated.

     

A class of weighted estimating equations for additive hazards models with covariates missing at random

Missing covariate data arise frequently in biomedical studies.In this article,we propose a class of weighted estimating equations for the additive hazards regression model when some of the covariates are missing at random.Time-specific and subject-specific weights are incorporated into the formulation of weighted estimating equations.Unified results are established for estimating selection probabilities that cover both parametric and non-parametric modelling schemes.The resulting estimators have closed forms and are shown to be consistent and asymptotically normal.Simulation studies indicate that the proposed estimators perform well for practical settings.An application to a mouse leukemia study is illustrated.     

响应变量存在缺失时部分线性模型的经验似然推断

考虑响应变量带有缺失的部分线性模型,采用借补的思想,研究了参数部分和非参数部分的经验似然推断,证明了所提出的经验对数似然比统计量依分布收敛到χ2分布,由此构造参数部分和函数部分的置信域和逐点置信区间.对参数部分,模拟比较了经验似然与正态逼近方法;对函数部分,模拟了函数的逐点置信区间.     

Dimension reduction for kernel-assisted M-estimators with missing response at random

Annals of the Institute of Statistical Mathematics - To obtain M-estimators of a response variable when the data are missing at random, we can construct three bias-corrected nonparametric...     

Testing conditional independence with data missing at random

It is known that conditional independence is a quite basic assumption in many fields of statistics. How to test its validity is of great importance and has been extensively studied by the literature. Nevertheless, all of the existing methods focus on the case that data are fully observed, but none of them seems having taken into account of the scenario when missing data are present. Motivated by this, this paper develops two testing statistics to handle such a situation relying on the idea of inverse probability weighted and augmented inverse probability weighted techniques. The asymptotic distributions of the proposed statistics are also derived under the null hypothesis. The simulation studies indicate that both testing statistics perform well in terms of size and power.