A new flavonoid with a benzoic acid substituent from Selaginella uncinata

6-（5-Carboxyl-2-methoxyphenyl）-apigenin （1）, a new flavonoid, was isolated from the 60% ethanol extract of Selaginella uncinata （Desv.） Spring. Its structure was established by spectroscopic methods. Compound 1 represents the first example of the flavonoids possessing a benzoic acid substituent at C-6.     

A new isochroman-4-one derivative from the peel of Musa sapientum L. and its total synthesis

A new isochroman-4-one,7,8-dihydroxy-3-methylisochroman-4-one was isolated from water soluble fraction of Musa sapientum L.Its structure was determined by spectroscopic evidences and its total synthesis has also been reported.The compound showed potent antihypertensive activity.     

Two new C-glycosylflavones from Mimosa pudica

Two new C-glycosylflavones were isolated from the whole plant of Mimosa pudica,and their structures were determined as 6,7,3′,4′-tetrahydroxyl-8-C-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranosyl flavone(1),5,7,3′,4′-tetrahydroxy-8-C[β-D- apiose-(1→4)]-β-D-glycopyranosyl flavone (2).Their structures elucidated by chemical and spectroscopic analysis including IR,MS,1D and 2D NMR spectra.     

A new coumarin from Wikstroemia indica （L.） C. A. Mey

A new coumadn was obtained from the stems and roots of Wikstroemia indica (L.) C.A.Mey.Its structure was elucidated as methyl 3-(2-hydroxy-4-(7-hydroxy-6-methoxy-2-oxo-2H-chromen-3-yloxy) phenyl) propanoate by spectroscopic methods.     

A new Compound from Chaenomeles sinensis (Thouin) Koehne

A new dihydrochromone derivative,named chaenomone,was isolated from the twigs of Chaenomeles sinensis (Thouin)Koehne .The structure was determined by spectroscopic methods.     

A new Furostanoside from Asparagus filicinus

A new furostanoside,aspafiliosde D(1) has been isolated from the root of Asparagus filicinus.Its structure was determined by spectral and chemical methods.     

A new Dendrobine-Type Alkaloid from Dendrobium nobile

A new dendrobine-type alkaloid has been isolated from stems of Dendrobium nobile lindl.Its structure has been identified on the basis of spectroscopic method.     

A New Alkaloid from Sinomenium acutum

Sinomenium acutum is widely used in East and South Asia for the treatment of many diseases, especially rheumatoid arthritis （RA）. The chemical research on Sinomenium acutum led to the isolation of a new alkaloid compound （1）. On the basis of chemical evidences and spectral analysis, 1 was identified as N-（1, 7-dimethoxylphenanthren-2-yl）acetamide.     

A new caffeic ester from Incarvillea mairei var. granditlora （Wehrhahn） Grierson

A new cafferic ester, （＋）-2-（1-hydroxyl-4-oxocyclohexyl） ethyl caffeate, was isolated from the 80% ethanol extract of the whole plants of Incarvillea mairei var. granditlora （Wehrhahn） Grierson. The structure of the compound was established by spectroscopic methods.     

A new tetrastilbene from Caragana sinica

A new tetrastilbene named carasinol D （1） was isolated from the roots of Caragana sinica. Its structure was elucidated by spectroscopic analysis. Compound 1 was obtained from carasinol B （2） by an acid-catalyzed conversion.     

A new dihydrobenzofuran lignanoside from Selaginella moellendorffii Hieron

A new lignanoside, （7R,8S）-7,8-dihydro-7-（4-hydroxy-3,5-dimethoxyphenyl）-1＇-formyl-3＇-y-methoxyl-8-hydroxymethylbenzo- furan-4-O-β-D-glucopyranoside （moellenoside A）, was isolated from Selaginella moellendorffii Hieron. Its structure was determined by spectroscopic evidences. 2007 Wei Sheng Feng. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.     

A new pyrrole alkaloid from Selaginella moellendorfii Hieron

One new pyrrole alkaloid,N-（2E）-3-（3,4-dihydrophenyl）prop-N₁-（4-aminoburyl）-3-pyrrole formaldehyde （1）,was isolated from the whole herbs of Selaginella moellendorfii Hieron.The structure was elucidated by spectroscopic analyses including UV,1R,1D NMR,2D NMR and MS methods.Additionally, compound 1 exhibited potent protective effect against the injury of human umbilical vein endothelial cell（HUVECs） induced by high concentrations of glucose in vitro.     

Bioactive compounds from Selaginella involven Spring that protect PC-12 cells

Two new compounds named as 3b 12 16-trihydroxy-6 8 11 13-abietatrien（1） （8R 80S）-4 40 8-trihydroxyl-3 30-dimethoxyl-90-lignanolide（2） and a new natural product 4 40-dihydroxyl-3 30 5 50-dimethoxyldiphenyl diketone（3） were isolated from the whole herbs of Selaginella involven Spring.The structures were elucidated by spectroscopic analyses including UV,IR,1D,2D NMR and MS methods.Additionally,these three compounds exhibited potent protective effect against the injury of PC-12 cells induced by hypoxia/reoxygenation.     

A new flavonoid from Selaginella tamariscina

6-(2-Hydroxy-5-acetylphenyl)-apigenin (1),a new flavonoid with a phenyl substituent,was first isolated from Selaginella tamariscina.Its structure was elucidated on the basis of 1D and 2D NMR as well as ESI-HR-MS spectroscopic analysis.     

A new flavone glycoside from Selaginella moellendorffii Hieron.

From the ethanol extract of Selaginella moellendorffii Hieron., a new flavone O-glycoside and three known flavone C-glycosides have been isolated and identified as 5-carboxymethyl-4'-hydroxyflavone-7-O-β-D-glucopyranoside 1, 6,8-di-C-β-D-glucopyrano-sylapigenin 2, 6-C-β-D-glucopyranosyl-8-C-β-D-xylopyranosyl apigenin 3, 6-C-β-D-xylopyranosyl-8-C-β-D-glucopyranosylapi-genin 4, respectively. Their structures were elucidated by spectroscopic methods.     

Pictalignans D-F,three new neolignan derivatives from Selaginella picta

Abstract

Three new neolignan derivatives (1–3), together with three known isolariciresinol derivatives (4–6) were isolated from Selaginella picta. Their structures were elucidated by spectroscopic methods (1D/2D NMR, HRESIMS and CD). All isolated compounds were assayed on the neuroprotective activity against the injury of HT-22 cells induced by L-Glutamate in vitro. All compounds displayed potent protective effect on HT-22 cells.     

Two new anthraquinone derivatives and one new triarylbenzophenone analog from Selaginella tamariscina

Abstract

Two new anthraquinone derivatives, selaginones A (1) and B (2), and one new triarylbenzophenone analog, selagibenzophenone B (3), were isolated from Selaginella tamariscina (Beauv.) Spring. Their structures were established by 1D-, 2D-NMR and HR-ESI-MS data. Compounds 1 and 2 represent the uncommon examples of aryl substituted anthraquinone derivatives. Especially, compound 2 is a unique anthranone with exceptional structural feature, in which a p-hydroxyphenyl moiety is attached to the C-10 position. Compound 3 is the second naturally occurring triarylbenzophenone and showed moderate activity against SMCC-7721 and MHCC97-H cell lines with IC₅₀ values of 39.8, 51.5 μM respectively.     

Two New Chromone Glycosides from Selaginella uncinata

Two new chromone glycosides,5-hydroxy-2,6,8-trimethylchromon-7-O-β-D-gluco-pyranoside,named uncinoside A;5-acetoxy-2,6,8-trimethylchromone-7-O-β-D-glucopyranoside, named uncinoside B,and a known chromone compound named 8-methyl eugenitol were isolated from Selaginella uncinate. Their structures were elucidated by spectra analysis of FAB-MS,1D NMR and 2D NMR including ^1H NMR,^13C NMR,HMQC,HMBC and single-crystal X-ray diffraction techniques.     

Uncinatic acids A-C,three new carboxylated flavonoids from Selaginella uncinata

Three new carboxylated flavonoids, uncinatic acids A-C(1–3), were isolated from the whole herb of Selaginella uncinata. Their structures were established on the basis of extensive NMR analysis including1 D, 2D NMR experiments and HR-ESIMS techniques. All of them share the carboxylation structural characteristic. Compounds 1 and 2 belong to novel naturally occuring furanoflavonoids which is firstly reported in genus Selaginella. Such furanoflavonoids with dicarboxylic acid structrure have never been discovered before. In addition, the isolates were tested for their cytotoxicity against A549 and BGC-823 cell lines in vitro.     

Five new benzophenone glycosides from the leaves of Aquilaria sinensis(Lour.) Gilg

Phytochemical investigation on the ethanol extract from the leaves of Aquitaria sinensis led to the isolation of five new benzophenone glycosides,aquilarinensides A-E(1-5).Their structures were elucidated by a combination of 1D and 2D NMR,HRMS,and chemical analysis.