A novel dosimetry system for computed tomography using phototransistor

Computed tomography (CT) dosimetry normally uses an ionization chamber 100 mm long to estimate the computed tomography dose index (CTDI), however some reports have already indicated that small devices could replace the long ion chamber to improve quality assurance procedures in CT dosimetry. This paper presents a novel dosimetry system based in a commercial phototransistor evaluated for CT dosimetry. Three detector configurations were developed for this system: with a single, two and four devices. Dose profile measurements were obtained with them and their angular responses were evaluated. The results showed that the novel dosimetry system with the phototransistor could be an alternative for CT dosimetry. It allows to obtain the CT dose profile in details and also to estimate the CTDI in longer length than the 100 mm pencil chamber. The angular response showed that the one device detector configuration is the most adequate among the three configurations analyzed in this study.     

Effects on skin dose from unwanted air gaps under bolus in photon beam radiotherapy

The dose under small air gaps located under bolus material of up to 10 mm have been measured with an Attix parallel plate ionization chamber and radiochromic film. For a 6 MV x-ray beam with 10 mm bolus, an air gap of 2 mm produced no reduction in skin dose when measured with the Attix chamber. An air gap of 4 mm will introduce a reduction of dose to the basal layer of approximately 0–4% depending on field size, angle of incidence and other patient specific parameters and a reduction of up to 10% could be seen at the basal cell layer for a 10 mm air gap. The 10% reduction was for a small x-ray field at 60 degrees angle of incidence and was a reduction in dose from 100% of D_max down to 90% of D_max. Results at oblique angles of incidence show that larger reductions in dose are seen with increasing angle of incidence. Radiochromic film results agree with the Attix chamber results measuring 2%±2% decrease for a 4 mm gap and 4%±2% for a 10 mm gap at normal incidence. Clinically, results show that small air gaps can reduce skin dose, however, at least 90% of maximum dose is still delivered for air gaps up to 10 mm.     

Investigation of a fibre-coupled beryllium oxide (BeO) ceramic luminescence dosimetry system

The purpose of this study is to investigate the potential use of a beryllium oxide (BeO) ceramic as a radioluminescence (RL) and optically stimulated luminescence (OSL) probe material for fibre-coupled luminescence dosimetry. A portable dosimetry system, named RL/OSL BeO FOD was developed, consisting of a 1 mm diameter, 1 mm long BeO ceramic cylinder coupled to a silica/silica optical fibre. The reader measures the RL signal and also uses a 450 nm laser diode to stimulate the BeO ceramic. A second background optical fibre is used to remove the stem effect. The RL/OSL BeO FOD was characterised in a solid water phantom, using a 6 MV x-ray beam. The RL was found to be reproducible and have a linear response to doses ranging from 30 cGy–15 Gy and dose rates from 100 cGy/min – 600 cGy/min. The OSL response was linear to doses of 10 Gy, becoming supralinear at higher doses. Measured percentage depth curves using the RL/OSL BeO FOD agreed with those measured using an IC15 ion chamber to within 5%, beyond the build up region. It was also found that the RL from BeO ceramic is unaffected by the delivered dose to the probe and hence, it remains constant for a given dose-rate. The insensitivity of the RL to accumulated dose makes BeO ceramic potentially capable of accurate dose-rate measurements without any corrections for the accumulated dose. This study demonstrates the feasibility of BeO ceramic as a versatile fibre-coupled luminescence dosimeter probe.     

Characterisation of 32P beta source for external radiation protection

Custom-made design of ³²P patch sources are used in brachytherapy applications. Use of this source requires external radiation protection. This implies measurement of absorbed dose rate to tissue at a depth of 0.07 mm. Towards this goal, 2.75 mCi ³²P patch source was locally developed. Characterization of this source has been carried out by measuring source parameters such as uniformity in the activity distribution and beam uniformity. The characterization also includes output measurements in terms of absorbed dose rate to air using an extrapolation chamber at 11, 20 and 30 cm from the source. Various correction factors which are dependent on the cavity length as well as independent of the cavity length were also determined in this study. The backscatter correction and Bragg–Grapy stopping power ratio were calculated using the Monte Carlo techniques. Using these correction factors and the measured absorbed dose rate to air, absorbed dose rate to tissue at a depth of 0.07 mm was determined. The study also includes measurements of H_p(0.07) and H_p(10) at different source-to-detector distances using an electronic pocket dosimeter.     

Equilibrium low temperature heat capacity of the spin density wave compound (TMTTF)<Subscript>2</Subscript>Br: effect of a magnetic field

We have investigated the effect of the magnetic field (B) on the very low-temperature equilibrium heat capacity c_eq of the quasi-1 D organic compound (TMTTF)₂Br, characterized by a commensurate Spin Density Wave (SDW) ground state. Below 1 K, c_eq is dominated by a Schottky-like A_ST^-2 contribution, very sensitive to the experimental time scale, a property that we have previously measured in numerous DW compounds. Under applied field (in the range 0.2–7 T), the equilibrium dynamics, and hence c_eq extracted from the time constant, increases enormously. For B ≥ 2–3 T, c_eq varies like B², in agreement with a magnetic Zeeman coupling. Another specific property, common to other Charge/Spin density wave (DW) compounds, is the occurrence of metastable branches in c_eq, induced at very low temperature by the field exceeding a critical value. These effects are discussed within a generalization to SDWs in a magnetic field of the available Larkin-Ovchinnikov local model of strong pinning. A limitation of the model when compared to experiments is pointed out.     

Neural network enhanced 3D turbo spin echo for MR intracranial vessel wall imaging

PurposeTo improve the signal-to-noise ratio (SNR) and image sharpness for whole brain isotropic 0.5 mm three-dimensional (3D) T₁ weighted (T₁w) turbo spin echo (TSE) intracranial vessel wall imaging (IVWI) at 3 T.MethodsThe variable flip angle (VFA) method enables useful optimization across scan efficiency, SNR and relaxation induced point spread function (PSF) for TSE imaging. A convolutional neural network (CNN) was developed to retrospectively enhance the acquired TSE image with PSF blurring. The previously developed VFA method to increase SNR at the expense of blur can be combined with the presented PSF correction to yield long echo train length (ETL) scan while the acquired image remains high SNR and sharp. The overall approach can enable an optimized solution for accelerated whole brain high-resolution 3D T₁w TSE IVWI. Its performance was evaluated on healthy volunteers and patients.ResultsThe PSF blurred image acquired by a long ETL scan can be enhanced by CNN to restore similar sharpness as a short ETL scan, which outperforms the traditional linear PSF enhancement approach. For accelerated whole brain IVWI on volunteers, the optimized isotropic 0.5 mm 3D T₁w TSE sequence with CNN based PSF enhancement provides sufficient flow suppression and improved image quality. Preliminary results on patients further demonstrated its improved delineation for intracranial vessel wall and plaque morphology.ConclusionThe CNN enhanced VFA TSE imaging enables an overall image quality improvement for high-resolution 3D T₁w IVWI, and may provide a better tradeoff across scan efficiency, SNR and PSF for 3D TSE acquisitions.     

Investigations into the reliability of SAR-OSL equivalent doses obtained for quartz samples displaying dose response curves with more than one component

Fast component dominated quartz single aliquot regenerative dose optically stimulated luminescence (SAR-OSL) dose response curves that display continuing growth at high doses are increasingly reported in literature. This behaviour would result in higher equivalent doses being obtained. Here we document the characteristics of OSL signals from fine (4–11 μm) and coarse (63–90 μm) quartz extracted from Romanian loess that display such behaviour. For very high doses (>1 kGy up to 5–15 kGy) the data could be closely fitted to a double saturating exponential regression model. Nonetheless, the saturation charcteristics of these fine and coarse quartz grains are very different, with average saturation chracteristic doses of D₀₁ ≈ 175 Gy and D₀₂ ≈ 1800 Gy in the case of the fine material, while in the case of the coarse material values of D₀₁ ≈ 55 Gy and D₀₂ ≈ 600 Gy have been obtained. Our results imply a hitherto unexplained mechanism in OSL production at high doses and question the reliability of obtaining SAR-OSL equivalent doses in the high dose region when a second function is needed to describe the dose response.     

Characterisation of a real-time fibre-coupled beryllium oxide (BeO) luminescence dosimeter in X-ray beams

For the first time the feasibility of using beryllium oxide (BeO) ceramics as a fibre-coupled radioluminescent dosimeter is investigated. BeO ceramic exhibits both radioluminescence (RL) and optically stimulated luminescence (OSL), and has the potential to be a near tissue equivalent alternative to Al₂O₃:C. A BeO fibre-coupled radioluminescence dosimeter is demonstrated and characterised for 6 MV X-rays and superficial X-ray energies, 150 kVp and 120 kVp. Based on the results, we demonstrate the capability of the RL BeO FOD for accurate and reproducible dose measurements with a linear dose rate and dose response. It has also been found that the percentage depth dose curves for 6 MV agreed with ion chamber measurements to within 2%, except in the build up region. For the 150 kVp and 120 kVp photon beams, the depth dose measurements agreed with ion chamber measurements to within 2.5% and 4%, respectively.     

深能级陷阱对FET的光瞬态特性、等效噪声电流和漏电流升高的影响

本文基于位于准费密能级下深受主陷阱和剩余空穴,在平衡(无光照)和非平衡(有光照)条件下单位时间内空穴浓度变化率的微分方程基础上,导出了指数衰减理论方程,可很好地解释深能级对FET光脉冲瞬态特性的影响,指出了深能级是衰减长尾产生的根本原因,并测定了GaAs MESFET、GaAlAs TEGFET Si JFET的光脉冲瞬态特性,验证了理论模型的准确性。探讨了能级深度E_T等因素对衰减曲线的影响。测定了上述三类器件的等效噪声电压与频率f之间的关系,应用文献[6]的公式得出了相应的等效噪声 关键词：     

Two-dimensional numerical simulation on galloping detonation in a narrow channel

The numerical simulations of the two-dimensional galloping detonation performed by using two-dimensional full Navier–Stokes simulations with a detailed chemistry model are presented. The detonation in a narrow channel with d = 5 mm, which is approximately twice the half-reaction length of hydrogen, shows a feature of galloping detonation with two initiations during its propagation under the laminar flow assumption. The distance between these two initiations is approximately 1300 mm, which causes the induction time behind the leading shock wave. As the channel width increases, the galloping feature diminishes. The detonation propagates approximately 4% lower than D_CJ for d = 10 and 15 mm. By increasing the channel width, the strength of the detonation increases, as shown in the maximum pressure histories. The effects of turbulence behind the detonation show that the galloping feature disappears, although its propagation velocity becomes 0.9 D_CJ. The strength of the detonation becomes significantly weak compared with the detonation propagating in the wide channel widths, and this feature is similar to the laminar assumption. The trend of the velocity deficits in the NS simulations agrees fairly well with the trend of the modified ZND calculations with η = 0.25.     

ONP Spectroscopy of Defects in Silicon

Optical nuclear polarization technique is used to study metastable properties of the gold donor center in silicon. A model of a deep defect’s symmetry changing C _3V  → C _1h  → D _2d with its charge state (D⁻ → D⁰ → D⁺) is proposed to account for the observed optically induced quenching and regeneration of Au⁰ centers.     

Embedding of insulating nano-inclusions in Y-123 superconductor as pinning centers: The influence of size

The optimization of flux line pinning in superconductors is one of the most efficient ways to improve the transport properties of these materials. The generation of effective artificial pinning centers in a controlled way and with optimal dimensions can contribute to the enhancement of pinning capability and to the improvement of the critical current densities J_c. In this work, we examined the effectiveness of an insulating inclusion in a type II superconductor as a pinning center with a size close to the penetration depth λ instead of the coherence length ξ. To this effect, insulating nano-pinning centres (100–150 nm) have been successfully embedded into superconducting YBa₂Cu₃O_7?d (Y-123) matrix by slightly doping with nano-particle alumina dispersions. Two alumina nano-particle dispersions with mean size diameters of about 130 nm and 150 nm which are considerably larger than the coherence length ξ of Y-123 were used. A systematic study of the relationship of J_c(H,T) with different amounts of D₁ and D₂-nanoalumina additions was performed to determine the optimum nano-particle doping contents. The results indicate that slight inclusions of D₁ or D₂-nanoalumina can effectively enhance the flux pinning capability of samples. The best flux pinning was observed in the sample with 10^?2 wt.% D₁-alumina and 3 × 10^?2 wt.% D₂-alumina. The present work suggests that the use of sufficiently large insulating inclusions in the nanometer sub-scale can stabilize the flux-line lattice. It also shows that the optimal size for an insulating inclusion, acting as a pinning center in bulk material, is more likely related to λ than to ξ.     

Analysis of phantom centering positioning on image noise and radiation dose in axial scan type of brain CT

ABSTRACT

This study examined the dose and image quality according to the position change of a human phantom in a CT scan. This study used an MDCT 128 Slice CT Scanner instrument. An axial scan was performed with a 16 cm CTDI phantom of a human phantom, and the dose was measured using a pencil chamber meter. The phantom was scanned 10 cm above and below the isocenter and 15 cm above the right and left. The position of the phantom is indicated by C-0 in the isocenter position, S-10 in the upper 10 cm, I-10 in the lower 10 cm, R-15 in the right 15 cm, and L-15 in the left 15 cm. The test was performed 30 times using the brain CT protocol to calculate the dose and the dose width product (DWP). The acquired images were analyzed using the ImageJ program. Statistical analysis was performed using SPSS with one-way ANOVA (p < .05). The mean DWP values of the CT scanner were C-0 31.97 mGy·cm, S-10 24.52 mGy·cm, I-10 24.28 mGy· cm, R-15 17.95 mGy·cm, and L15 17.6 mGy·cm. Compared to the isocenter (C-0), the DLP values measured at each site were 23.3% for S-10, 24% for I-10, 43.8% for R-15, and 44.9% for L15. A significant difference in the one-way ANOVA statistical process was observed (p>0.05). C-0 was measured to be 7.42 HU, S-10 7.87 HU, I-10 8.4 HU, R-15 117 HU, and L-15 13.6 HU for evaluating the image quality. Compared to C-0, S-10 was 5.39%, I-10 was 13.2%, R-15 was 57.6%, and L-15 was 83.2%. The PSNR for S-10, I-10, R-15, and L-15 was 17.37, 17.5, 16.62, and 16.37 dB, respectively. A good quality image can be obtained by positioning the subject precisely in the isocenter in the axial scan, if possible, because the irradiated dose to the subject is low, which can lead to an increase in noise in image reconstruction.     

Interaction of Cholesterol with Dimethyl and Diethyl Sulfoxides

The complexing of cholesterol with dimethyl and diethyl sulfoxides in carbon tetrachloride is investigated by the method of IR spectroscopy. It is established that the hydrogen bond is formed between the oxygen of the sulfoxide group of sulfoxides and the hydrogen of the hydroxyl group of cholesterol. The equilibrium constants (K _eq) of the complexes of cholesterol with dimethyl sulfoxide (K _eq = 93 liters/mole) and diethyl sulfoxide (K _eq = 98 liters/mole) at 23°C are determined.     

Combustion effects in confined explosions

Results of shock-dispersed-fuel (SDF) explosion experiments are presented. The SDF charge consisted of a spherical 0.5-g PETN booster surrounded by 1 g of fuel, either flake aluminum (Al) powder or TNT. The charge was placed at the center of a sealed chamber. Three cylindrical chambers (volumes of 6.6, 20, and 40 l with L/D = 1) and three tunnels (L/D = 3.8, 4.65, and 12.5) were used to explore the influence of chamber volume and geometry on completeness of combustion. Detonation of the SDF charge created an expanding cloud of explosion product gases and hot fuel (Al or TNT). When this fuel mixed with air, it formed a turbulent combustion cloud that consumed the fuel and liberated additional energy (31 kJ/g for Al or 15 kJ/g for TNT) over and above detonation of the booster (6 kJ/g) that created the explosion. Static pressure gauges were the main diagnostic. Pressure and impulse histories for explosions in air were much greater than those recorded for explosions in nitrogen—thereby demonstrating that combustion has a dramatic effect on the chamber pressure. This effect increases as the confinement volume decreases and the excess air ratio approaches values between 2 and 3.5.     

The pure rotational spectrum of ZnS (XΣ)

The pure rotational spectrum of ZnS (X¹Σ⁺) has been measured using direct-absorption millimeter/sub-millimeter techniques in the frequency range 372–471 GHz. This study is the first spectroscopic investigation of this molecule. Spectra originating in four zinc isotopologues (⁶⁴ZnS, ⁶⁶ZnS, ⁶⁸ZnS, and ⁶⁷ZnS) were recorded in natural abundance in the ground vibrational state, and data from the v = 1 state were also measured for the two most abundant zinc species. Spectroscopic constants have been subsequently determined, and equilibrium parameters have been estimated. The equilibrium bond length was calculated to be r_e  2.0464 Å, which agrees well with theoretical predictions. In contrast, the dissociation energy of D_E  3.12 eV calculated for ZnS, assuming a Morse potential, was significantly higher than past experimental and theoretical estimates, suggesting diabatic interaction with other potentials that lower the effective dissociation energy. Although ZnS is isovalent with ZnO, there appear to be subtle differences in bonding between the two species, as suggested by their respective force constants and bond length trends in the 3d series.     

The relationship between current and channel diameter of 30 cm long laboratory sparks

In this study the dependence of channel diameter of 30 cm long sparks on discharge current is analyzed using a photographic technique. The results show the radial channel intensity variation follows a Gaussian distribution. The channel diameter (D), defined as the width of the intensity profile at 10% level, increases with the increasing peak current (I_p) up to 3 kA. The relationship between the two parameters can be represented by the equation, D = 8.36 ln(I_p) + 1.598, where D is in mm and I_p is in kA. The experimental results agree reasonably well with the available theory.     

The estimation of basic experimental parameters in the fine-grained quartz multiple-aliquot regenerative-dose OSL dating of Chinese loess

The sensitivity-corrected multiple-aliquot regenerative-dose (MAR) protocol provides a reliable approach for fine-grained quartz optically stimulated luminescence (OSL) dating. For reliable estimation of the equivalent dose (D_e), we investigated certain basic experimental parameters in the fine-grained quartz MAR OSL dating of Chinese loess. (1) For suitable bleaching of the natural OSL signal of the regenerative-dose aliquots, the effect of bleaching duration using sunlight, SOL2 and blue LEDs on D_e was studied, and it is found that the appropriate method is a short-duration SOL2 (e.g. 5 min) or blue LEDs (e.g. 60 s) bleaching. (2) To select the appropriate test dose, the relationship between the test dose and D_e was investigated based on three samples having D_e values of approximately 11, 31 and 137 Gy respectively. It is suggested that the test dose for sensitivity correction may be limited to less than approximately 10–20 Gy. (3) Three commonly used fitting modes for quartz OSL growth curve were compared at three regenerative-dose scales. The results indicate that the mode of two saturating exponential functions plus a constant is appropriate and universal. (4) The comparison of D_e values derived using OSL approach with those obtained using the recuperated OSL (ReOSL) protocol shows that the reliable D_e estimation in the fine-grained quartz MAR OSL dating of Chinese loess may be limited to less than approximately 300 Gy. (5) The comparison of growth curves for 18 samples from the Weinan, Xifeng and Jingyuan sites shows that it is feasible to construct a standardized growth curve (SGC) for fine-grained quartz OSL signal in the Chinese Loess Plateau (CLP).     

Improving the accuracy and precision of equivalent doses determined using the optically stimulated luminescence signal from single grains of quartz

Optically stimulated luminescence (OSL) measurements of quartz are widely used to measure equivalent dose (D_e). At radiation doses above ～100 Gy, saturation of traps results in a decrease in the rate of growth of the OSL signal, and this makes calculation of D_e increasingly difficult. A series of dose recovery experiments was undertaken using single grains of quartz from Kalambo Falls, Zambia to explore saturation of single grains. When the OSL signal from many grains is averaged, the characteristic dose (D₀) is 47 Gy, typical of published values for quartz. However, D₀ for individual grains varies from ～10 to 100 Gy. Doses up to two times the average D₀ could be accurately recovered, but above this dose the D_e became increasingly underestimated. Overdispersion for this type of experiment should be zero, but was observed in all data sets; furthermore the value of overdispersion increased with D_e. An additional acceptance criterion, the Fast Ratio, is suggested for single grain OSL analysis. This criterion assesses the relative contribution of the fast component of the OSL signal. Including this as an additional acceptance criterion leads to an improved precision, with overdispersion reduced to zero, and improved accuracy in dose recovery at high doses.     

Bilateral comparison of an alanine/ESR dosimetry system at radiotherapy dose levels

To improve the signal to noise ratio and to reduce the uncertainty for Electron Spin Resonance (ESR) readout of alanine dosimeters irradiated in the dose range of 2–10 Gy, new spectrometer settings have been proposed for microwave power, modulation amplitude, conversion time, sweeps of the spectrum and orientations of the alanine pellets (Garcia et al., 2009). To check the reliability of the new spectrometer settings at radiotherapy dose levels, a bilateral dose comparison in terms of absorbed dose to water was performed between the CEA LIST Laboratoire National Henri Becquerel (LNHB) and the Radiometrology Center of the China Institute of Atomic Energy (RC-CIAE). Eighteen alanine dosimeters were irradiated with 2, 5 and 10 Gy. Each dosimeter was readout with the new spectrometer settings developed within the framework of the collaboration. The results of D_meas/D_nom at both laboratories in the dose range of 2–10 Gy are within the tolerance limits. The maximum deviations observed are within the extended uncertainties (k = 2).