共查询到20条相似文献,搜索用时 31 毫秒
1.
M. Khakimov R. F. Ambartsumova B. Tashkhodzhaev M. Yu. Antipin Kh. M. Shakhidoyatov 《Chemistry of Heterocyclic Compounds》2001,37(8):1005-1010
We have synthesized 3-substituted 4-alkyl-5-imino-4,5-dihydro-1,2,4-thiadiazoles by reaction of 3-alkyl(benzyl)thio-5-amino-1,2,4-thiadiazoles with methyl iodide or ethylene chlorohydrin. In the reaction with epichlorohydrin, addition of an oxirane molecule occurs with formation of tetrahydropyrimido[2,1-b]-1,2,4-thiadiazoles. 相似文献
2.
The review summarizes published data on the structure, tautomeric properties, direct, indirectmethods of preparation, chemical properties, and reactivity of 5-amino-3-nitro-1,2,4-triazole which is one of the most important synthons of the symmetric triazole series. 相似文献
3.
Zusammenfassung Es wird die Darstellung von drei verschiedenen 5-aminoalkyl-substituierten 3-Amino-1,2,4-triazolen sowie des 5-(4-Pyridyl)-3-amino-1,2,4-triazols beschrieben. Die Ergebnisse pharmakologischer und bakteriologischer Untersuchungen von einigen Verbindungen werden mitgeteilt. 相似文献
4.
Long-Chih Hwang 《高等学校化学学报》1998,19(Z1):33
A facile ring closure reaction with the N-l nitrogen of the 1,2,4-triazine ring occurs when 3-amino-6-hydrazino-1,2,4-triazin-5-one(1) is refluxed in either acid, orthoester/dimethylformamide, carbon disulfide, cyanogen bromide or nitrous acid. 3-amino-2-benzyl-6-hydrazino-1,2,4-triazin-5-one(2), containing the benzyl group on the 2-position of 1, can not be cyclized under the above reaction conditions except refluxed with carbon disulfide in pyridine-water(1:1), which will pass through a novel rearrangement cyclization to afford a bicycloheterocyclic compound,6-amino-3-benzylmercapto-1,2,4-triazolo[3,4-f][l,2,4]triazin-8(7H)-one(3). The mechanisms of their ring closure and rearrangement cyclization will be presented in detail. 相似文献
5.
A series of 3-amino-1,2,4-benzothiadiazine 1-oxides were obtained from the corresponding 3-thiomethyl ethers by displacement with a series of amines; examples of the last included variously substituted piperazines and piperidines. 相似文献
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7.
Krylov A. S. Tolstyakov V. V. Gurzhiy V. V. Dogadina A. V. 《Russian Journal of General Chemistry》2021,91(1):72-76
Russian Journal of General Chemistry - A series of new 6-phosphonylated 1H-imidazo[2,1-c][1,2,4]triazoles was synthesized by the reaction of diethyl chloroethynylphosphonate with 2-substituted... 相似文献
8.
Nitrogen-rich heterocycles are increasingly used in energetic chemistry with the aim to achieve superior performance of the new energetic materials. Combining such building blocks into biheterocycles increases energy output while at the same time retains low sensitivity. Herein, we report the synthesis and characterization of a compound containing a 5-amino-1,2,4-triazole moiety connected with a 1,2,4-oxadiazole ring. The trichloromethyl group attached to the oxadiazole ring offers an attractive point for further transformations into potentially energetic compounds. 相似文献
9.
Ming Li Guilong Zhao Lirong Wen Xiao Wang Xiaomao Zou Huazheng Yang 《Monatshefte für Chemie / Chemical Monthly》2005,136(12):2045-2049
Summary. A novel coupling reaction of 4-amino-5-mercapto-3-substituted-1,2,4-triazoles to generate symmetrically substituted hydrazines,
N,N′-bis(5-mercapto-3-substituted-1,2,4-triazol-4-yl)hydrazines was unexpectedly observed. Five examples are presented to demonstrate
this reaction. All isolated products were unambiguously characterized. 相似文献
10.
Ester derivatives of N-phosphorylated 3(5)-methylpyrazole and 3-amino-1,2,4-triazole, respectively, have been synthesized. The results of hydrolysis studies are described. 相似文献
11.
LIU Hai-ping LINing BI Si-fu LI De-yu ZOU Zhong-li 《高等学校化学研究》2008,24(1):101-105
The effects of organic additive, 3-amino-5-mercapto-1,2,4-triazole (AMTA) on bath stability, deposition rate, reaction activation energy, and Ni-P coating composition in acidic electroless nickel plating were investigated. Polarization curve method and infrared reflection spectroscopy were used to analyze the mechanism of the effect of AMTA on electroless nickel deposition. It was observed that AMTA improved bath stability, decreased the deposition rate, and increased the reaction activation energy. It was also revealed that AMTA decreased the phosphorus content and increased the sulfur content in Ni-P coating. In addition, AMTA inhibited the anodic oxidation of hypophosphite and accelerated the cathodic reduction of Ni^2+. Infrared reflection spectroscopy result indicates that AMTA was adsorbed on the surface of Ni-P and interacted with Ni^2+ to form an AMTA-Ni^2+ compound. On the basis of the results of this study, the mechanism of the effect of AMTA on electroless nickel deposition was deduced. 相似文献
12.
V. V. Dotsenko T. Yu. Evmeshchenko N. A. Aksenov I. V. Aksenova G. D. Krapivin D. I. Sharapa F. F. Chausov V. D. Strelkov L. V. Dyadyuchenko 《Russian Journal of General Chemistry》2018,88(10):2050-2057
Aminomethylation of xanthane hydride (5-amino-1,2,4-dithiazole-3-thione) with the RNH2–HCHO system has resulted in the formation of the derivatives of new heterocyclic system (3,7-dihydro-5H-[1,2,4]-dithiazolo[4,3-a][1,3,5]triazine) in low yields. The reaction of xanthane hydride with dicyandiamide has led to thioammeline [4,6-diamino-1,3,5-triazine-2(5Н)-thione]. Some practically important properties of xanthane hydride and its derivatives have been investigated. Xanthane hydride has efficiently exhibited carbon steel corrosion in neutral aqueous media. The prepared compounds have not exhibited growth-regulating or antidote activity to herbicide 2,4-D. 相似文献
13.
V. N. Britsun I. M. Bazavova A. N. Esipenko M. O. Lozinskii 《Chemistry of Heterocyclic Compounds》2003,39(12):1623-1626
The reactions of 4-amino-3-methylthio-5-oxo-6-R-4,5-dihydro-1,2,4-triazines with arylsulfonylacetonitriles and with dinitriles of sulfonyldiacetic acid and methylenebis(sulfonylacetic) acid have been studied. 7-Amino-3-R-8-(R'-sulfonyl)-1,4-dihydropyrazolo[5,1-c][1,2,4]triazin-4-ones have been synthesized and these are the first representatives of geminal sulfones in which the heterocyclic ring is bound directly to the sulfur atoms of the sulfonyl groups. 相似文献
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15.
I. M. Bazavova V. N. Britsun A. N. Esipenko M. O. Lozinskii 《Chemistry of Heterocyclic Compounds》2003,39(6):809-812
A study was carried out on the reaction of 4-amino-6-R-2,3,4,5-tetrahydro-3-thioxo-1,2,4-triazin-5-ones with halo ketones in alkaline media to yield 4-amino-6-R-4,5-dihydro-3-phenacylthio-1,2,4-triazin-5-ones, which then convert to 8H-3-R-7-aryl-1,2,4-triazino[3,4-b][1,3,4]thiadiazin-4-ones. 相似文献
16.
Seventeen novel fused heterocycles have been prepared by the intramolecular Mannich reaction of 4-amino-3-aryl-5-mercapto-1,2,4-triazole with aldehydes in the presence of acid, Yield: 32 ~ 90%. These compounds were screened for their antimicrobial activities. 相似文献
17.
Raafat M. Shaker Ashraf A. Aly 《Phosphorus, sulfur, and silicon and the related elements》2013,188(11):2577-2613
The synthesis and reactions of substituted 4-amino-1,2,4-triazole-5-thione derivatives as well as their biological activity are reviewed. 相似文献
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19.
Nucleosides of 5-substituted-1,2,4-triazole-3-carboxamides were prepared by the acid-catalyzed fusion procedure and by glycosylation of the appropriate trimethylsilyl derivative. The following nucleosides were obtained in two steps starting from methyl 4-substituted-1,2,4-triazole-3-carboxylates: 5-chloro-1-β- D -ribofuranosyl-1,2,4-triazole-3-carboxamide ( 6 ), 3-chloro-1-β- D -ribofuranosyl-1,2,4-triazole-5-carboxamide ( 5 ), 3-nitro-1-β- D -ribofuranosyl-1,2,4-triazole-5-carboxamide ( 12 ), 3-amino-1-β- D -ribofuranosyl-1,2,4-triazole-5-carboxamide ( 13 ), 5-methyl-1-β- D -ribofuranosyl-1,2,4-triazole-3-carboxamide ( 15 ), and 3-methyl-1-β- D -ribofuranosyl-1,2,4-triazole-5-carboxamide ( 16 ). In addition, 5-amino-1-β- D -ribofuranosyl-1,2,4-triazole-3-carboxamide ( 7 ), and 1-β- D -ribofuranosyl-1,2,4-triazole-3-carboxamide-5-thiol ( 8 ) were prepared from 6 . 相似文献
20.
V. M. Chernyshev A. V. Chernysheva V. A. Taranushich 《Russian Journal of Applied Chemistry》2006,79(5):783-786
Various synthetic routes to esters and amides of 5-amino-1,2,4-triazole-3-carboxylic and 5-amino-1,2,4-triazol-3-ylacetic acids were examined. 相似文献