Synthesis and Characterization of Novel Orange-emitting Iridium(III) Complexes with Diphenylquinoline Ligands Containing Fluorinated Substituent

Recently, the iridium complexes as phosphorescent emitter in organic light-emitting diodes (OLEDs) have attracted much attention since the realization of a high efficiency OLED device based on the complex fac tris(2-phenylpyridine)iridium [Ir(ppy)3]1-4. T…     

Synthesis and Characterization of Novel Lanthanocene Complexes with Dichalcogenolate o-Carboranyl Ligands

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Synthesis and Characterization of Chiral Organogallium and Indium Complexes with Salen Ligands

Several new chiral organogallium and indium complexes with chiral Salen(1 and 2) as anxciliary ligands have been synthesized and characterized by elemental analysis,IR,^1H NMR and Mass spectroscopy.For the gallium,Mono and bimetallic complexes were obtained,whereas ring closure complexes of indium were obtained.     

Synthesis and Characterization of Complexes of Te(IV) with Sulfur and Selenium Containing Ligands: Crystal and Molecular Structure of Trichloro(4-methoxyphenyl)tellurium(IV)· N -methylbenzothiazole-2-( 3H )-thione

We report the synthesis and characterization of two new complexes of trichloro(4-methoxyphenyl)tellurium(IV) with N -methylbenzothiazole-2-( 3H )-thione ( 1 ) and N -methylbenzothiazole-2-( 3H )-selone ( 2 ). Both are obtained as air-stable complexes by the addition of a 1:1 molar ratio of the substituted tellurium(IV) trichloride with the appropriate ligand in tetrahydrofuran under an atmosphere of dry nitrogen. Both ( 1 ) and ( 2 ) have been characterized by 1 H and 13 C NMR spectroscopy, elemental analysis, and, in the case of ( 1 ), by a single crystal x-ray diffraction study. The molecular structure of ( 1 ) shows an approximately square-based pyramidal structure with one short Te--Cl bond [2.388(2)Å] trans to a very long Te--S linkage [2.883(2)Å]. A comparison with the related structures of some heavy main group elements is included.     

Synthesis and Characterization of Thermotropic Liquid Crystalline Complexes Containing Ferrocenyl Group

ＳｙｎｔｈｅｓｉｓａｎｄＣｈａｒａｃｔｅｒｉｚａｔｉｏｎｏｆＴｈｅｒｍｏｔｒｏｐｉｃＬｉｑｕｉｄＣｒｙｓｔａｌｌｉｎｅＣｏｍｐｌｅｘｅｓＣｏｎｔａｉｎｉｎｇＦｅｒｒｏｃｅｎｙｌＧｒｏｕｐＺｈａｎＭｅｉＬＩＵ；ＷｅｉＬＩＡＮ，ＨａｉＸｉａＳＨＩ；Ｔｏｎ...     

Synthesis and Characterization of Novel Orange-emitting Iridium（Ⅲ） Complexes with Diphenylquinoline Ligands Containing Fluorinated Substituent

Three new cyclometalated iridium（m） complexes based on ligands of diphenylquinoline with fluorinated subsfituents were prepared, and characterized by elemental analysis （EA）, ^1H NMR, and mass spectroscopy （MS）. The photophysical and electrophosphorescent properties of the complexes were briefly discussed.     

Synthesis, Characterization and Cytotoxicity of Ammine/Methylamine Platinum(Ⅱ) Complexes with Carboxylates

Seven novel platinum (Ⅱ) complexes [Pt (Ⅱ) (NH3) (CH3NH2) X2] (Ⅰ -Ⅶ) (X: CH3COO- ,CH2 ClCOO - , CHCl2COO -, C6H5-COO - , p-CH3O-C6H4 -COO - , p-NH2-C6 H4 -COO - , p-NO2 -C6 H4 -COO-) were prepared and characterized by means of elemental analysis, molar conductivity, thermal analysis,IR, UV, and 1 H NMR spectrometries. The cytotoxicity against HCT-8, BGC-823, MCF-7, EJ, and HL-60 cell lines increases in the following sequence: cisplatin ＞Ⅳ＞Ⅴ＞Ⅵ＞Ⅶ＞Ⅰ＞Ⅱ＞Ⅲ. Moreover, the complexes(Ⅰ -Ⅶ) display substantially greater activities against EJ and HL-60 cell lines than those against the cell lines from other carcinomas. They can induce a concentration-dependent accumulation of HL-60 cells in the G2/M phase of the cell cycle as cisplatin. There is no significant correlation between total DNA platination levels and cytotoxicity of the complexes.     

Synthesis and Characterization of Novel Biodegradable Polyamides Containing α-amino Acid

The polyamides were obtained from 1,6-hexanediamine and diacylchloride which incorporated α -amino acid residues through interfacial polycondensation. High molecular weight (η_inh = 1.05–1.18 dL/g) polymers were produced with high yields. The structure of polyamides was verified by FT-IR and ¹H NMR spectra. They showed a remarkable ability to develop high crystallinity with melting temperatures in the range 117–191°C and was stable up to 350°C under nitrogen. Two methods such as alkali hydrolysis (10% NaOH w/v, 80°C) and enzymatic hydrolysis were employed for assessing the susceptibility of these polyamides to degradation. A preliminary investigation of the 5-fluorouracil (5-FU) release characteristics of these polyamides showed that the release rate increased with increasing water absorption of the polymers.     

Synthesis,Crystal Structure and Catalytic Activity Palladium (Ⅱ) Complexes Containing Bulky Azole Ligands

Bulky azole ligands in combination with PdCl_2 provide three new palladium(II) complexes. All these complexes, as pre-catalysts, have high catalytic efficiency for the Suzuki-Miyaura cross-coupling reactions of sterically hindered aryl chlorides and good to high yields are obtained with low catalysts loadings(0.1 mol%) under mild conditions in air.     

New Half-sandwich Zirconium（IV） Complexes Containing Salicylaldimine Ligands： Synthesis,Characterizations and Catalytic Properties

Two new half-sandwich zirconium（IV） complexes bearing salicylaldimine ligands of the type Cp＊Zr[2-tBu-4-R-6-（CH=NiPr）C6H2O]C12[R=H（1）, tBu（2）] were prepared by the reaction of Cp＊ZrC13 with the corresponding lithium of salicylaldimine ligands 2-tBu-4-R-6-（CH=NiPr）C6H2OLi[R=H（LiLa）, tBu（LiLb）]. Com- plexes 1 and 2 were characterized by 1H NMR, BC NMR spectroscopy and elemental analysis. When activated with AliBu3 and Ph3CB（C6F5）4, both complexes 1 and 2 exhibited reasonable catalytic activities for ethylene polymeriza- tion, producing polyethylenes with moderate molecular weight. Complexes 1 and 2 also exhibited reasonable catalyt- ic activities for ethylene copolymerization with 1-hexene, producing poly（ethylene-co-l-hexene）s with moderate molecular weight and reasonable 1-hexene content.     

Synthesis and Characterization of Silver–Platinum Bimetallic Nanowires and Platinum Nanotubes

A galvanic replacement reaction was used to prepare silver–platinum bimetallic nanowires and platinum nanotubes. Silver nanowires, prepared by boiling aqueous silver nitrate with sodium citrate in the presence of small amount of sodium hydroxide, were used as the sacrificial template in the galvanic reaction to prepare silver–platinum bimetallic nanowires and ultimately hollow platinum nanotubes. The resulting nanomaterials are stable and can be isolated without core aggregation or decomposition. These new materials have been characterized by transmission electron microscopy, energy dispersive X-ray analysis, and inductively coupled plasma atomic emission spectroscopy.     

Hydrothermal Syntheses,Crystal Structures,and Characterization of Two Zinc(Ⅱ) Complexes Containing Flexible Bis(benzimidazole) Ligands

Two zinc(Ⅱ) complexes, namely, [Zn(L_1)Cl_2]_2(1) and {[Zn(L_2)(tbta)]·3H_2O}n(2)(L_1 = 1,3-bis(2-methylbenzimidazol-1-ylmethyl)benzene, H2 tbta = tetrabromoterephthalic acid, L2_ = 1,3-bis(2-methylbenzimidazol-1-yl)-2-propanol), have been successfully obtained under hydrothermal conditions. Complex 1 displays a binuclear structure which is further extended into a 1D supramolecular chain through π-π stacking. Complex 2 features a 2D(4,4) network based on a L2/tbta2- double linker. The thermal stability, fluorescence properties and catalytic activities of two complexes for the degradation of methyl orange in a Fenton-like process were discussed.     

Synthesis and Characterization of Aryl Acylguanidines and Their Copper(Ⅱ) Complexes

A series of eight N-mono-substituted aryl acylguanidines L~(1～8) were synthesized from the reactions of their parent acylthioureas and respective primary amines, including five R~1C(O)N=C(NHR~2)_2 with balanced arms(denoted as R~1–R~2–R~2: Ph–Ar'–Ar', L~1(1); Ph–Ar'–Ar', L~2(2); 1-Naph–Ar'–Ar', L~3(3); 1-Naph–Ar'–Ar', L~4(4); 2-Naph–Ar'–Ar', L`5(5); Ar' = 2,6-Me_2C_6H_3, Ar' = 2,6-iPr_2C_6H_3) and three R~1C(O)N=C(NHR~2)NHR~3 with unbalanced arms(denoted as R~1–R~2–R~3: Ph–Ar'–Ph, L~6(6); Ph–Ar' –Ph, L~7(7); Ph–Ar' –Ar', L~8(8)). Treatment of L~(1～5)(1～5) with copper acetate in a molar ratio of 2:1 in dichloromethane led to the formation of homoleptic Cu(Ⅱ) complexes trans-L_2~(n')Cu(9～13), in which the Cu(Ⅱ) center was stabilized by deprotonated ligands Ln'(n = 1～5) in the O,N-bidentate mode. When similar reactions of L~6(Ph–Ar'–Ph)(6) and L~7(Ph–Ar'–Ph)(7) that contain unbalanced arms were investigated, the Cu(Ⅱ) products trans-L_2~(6')Cu(14) and trans-L_2~(7')Cu(15) were formed by deprotonating the bulky amine groups in Ln(-NHAr' for L~6 and-NHAr' for L~7) rather than the-NHPh group. In sharp contrast, trans-L_2~(8')Cu(16) was obtained from two-arm unbalanced L~8(Ph–Ar'–Ar')(8) not by deprotonating the more bulky-NHAr' group but the relatively less bulky-NHAr' group. In a further exploration, the reaction of 1:1 mixed ligands Ln and Lm with copper acetate was found to give only homoleptic Cu(Ⅱ) complex L_2~(n')Cu instead of the heteroleptic one L~(n')CuL~(m'). The in vitro antibacterial activity of L~n was evaluated against S. aureus, E. coli and C. albicans by determining the minimum inhibitory concentrations(MICs) using Kirby-Bauer test.     

Synthesis and Characterization of 2,6-Bis(imino)phenoxy Cobalt Complexes

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Synthesis,Crystal Structure,Spectroscopic Property and Redox Behavior of Zinc(Ⅱ) Complexes Containing Oligoaniline-functionalized Terpyridine Ligands

Two novel mono-nuclear zinc(Ⅱ) complexes with oligoaniline-functionalized terpyridine ligands have been synthesized and verified by 1H-NMR,13C-NMR,Elemental Analysis (EA) and X-ray Diffraction (XRD). The UV-vis spectra show the ligand-centered (LC) π-π* transitions and intra-ligand charge transfer (1ILCT) transitions,and the 1ILCT band red-shifts with the increasing number of aromatic amine groups in the ligands. Complex [Zn(L1)2](PF6)2 with an aromatic amine group in ligand shows a strong emission peak at 523 nm in the MeCN solution at 293 K and a blue-shifted band at 517 nm in the alcoholic glass at 77 K. However,for complex [Zn(L2)2](PF6)2 containing aniline dimer modified ligand,no apparent emission can be observed in the MeCN solution at room temperature due to a PET non-radiative decay pathway. Both of them show multiplicate redox processes based on oligoaniline and terpyridine units. The shifts of redox potentials also reflect the D-A interactions between the oligoaniline units and [Zn(TPY)2]2+ core.     

Synthesis and Characterization of Ru(II) Complexes with π-Expansive Imidazophen Ligands for the Photokilling of Human Melanoma Cells

Ru(II) complexes were synthesized with π-expanding (phenyl, fluorenyl, phenanthrenyl, naphthalen-1-yl, naphthalene-2-yl, anthryl and pyrenyl groups) attached at a 1H-imidazo[4,5-f][1,10]phenanthroline ligand and 4,4′-dimethyl-2,2′-bipyridine (4,4′-dmb) coligands. These Ru(II) complexes were characterized by 1D and 2D NMR, and mass spectroscopy, and studied for visible light and dark toxicity to human malignant melanoma SK-MEL-28 cells. In the SK-MEL-28 cells, the Ru(II) complexes are highly phototoxic (EC₅₀ = 0.2–0.5 µm ) and have low dark toxicity (EC₅₀ = 58–230 µm ). The highest phototherapeutic index (PI) of the series was found with the Ru(II) complex bearing the 2-(pyren-1-yl)-1H-imidazo[4,5-f][1,10]phenanthroline ligand. This high PI is in part attributed to the π-rich character added by the pyrenyl group, and a possible low-lying and longer-lived ³IL state due to equilibration with the ³MLCT state. While this pyrenyl Ru(II) complex possessed a relatively high quantum yield for singlet oxygen formation (Φ_∆ = 0.84), contributions from type-I processes (oxygen radicals and radical ions) are competitive with the type-II (¹O₂) process based on effects of added sodium azide and solvent deuteration.     

Synthesis and Characterization of α-Hexadecyl-DOTA and its Gd(III) Chelate

Introduction Recent interest in polyazamacrocyclic paramagnetic Gd(III) chelates largely results form their clinical appli-cation for magnetic resonance imaging (MRI) contrast agents. The ligand DOTA (1,4,7,10-tetraazacyclodo- decane-N,N',N',N'-tetraacetic acid) forms one of the most thermodynamically stable and kinetically inert complexes with the trivalent lanthanide cations of any known chelate. These properties make Gd-DOTA one of the most effective and the safest MRI contrast …     

Synthesis,Characterization and Cytotoxicity of Ammine/Methylamine Platinum（Ⅱ） Complexes with Carboxylates

Introduction Cisplatinisoneofthemostactivechemotherapeu ticagentsavailableforthetreatmentofavarietyof cancers,especiallytesticularcancerandovariancanc er.However,itsclinicalutilityisrestrictedbyboththe drugresistanceandtoxicity.Sincethediscoveryofan tican…     

Synthesis and Characterization of Poly(ether imide)s Containing m-Methyl and Phthalazinone Moieties

Aromatic polyimides are distinguished for their excellent mechanical and thermal properties in many engineering fields1. However, aromatic polyimides are normally insoluble in common organic solvents, which restricts their applications in some fields. Many efforts have been taken to improve their solubility. Introducing bulky side groups and non-coplanar structure into polymers bone chains is a good way to obtain the polymers with excellent mechanical and thermal properties2. In this paper…