共查询到20条相似文献,搜索用时 98 毫秒
1.
ZhenLingLIU ZhongJianJIA XuanTIAN HongWANG 《中国化学快报》2004,15(2):197-199
Two new dihydroagarofuran sesquiterpenes with a novel substitution pattern:1α-(α-methyl)-butanoyl-2α,15-diacetoxy-4β-hydroxy-9β-(β-)furancarboxy-β-dihydroagarofuran (1) and 1α,2α-di-(α-methyl)-butanoyl-4β-hydroxy-9β-(β-)furancarboxy-15-acetoxy-β-dihydro-agaro-furan (2) were isolated from Euonymus nanoides. Their structures were elucidated by means of ^1H and ^13C NMR spectroscopic studies, including 2D NMR technique. 相似文献
2.
以滇桂艾纳香枝叶为原料,经陶瓷膜、有机膜分离,醇沉、Sevag法除蛋白,DEAE-纤维素柱层析和SephadexG- 10,SephadexG-50凝胶柱色谱纯化得到的BROS;经HPGPC检测分析表明,BROS为均一寡糖,MALDI-TOF-MS测定分子量为1314.用IR,HPLC,甲基化分析,GC-MS,NMR (1H NMR,13C NMR,1H)HCOSY,HMQC和HMBC)等方法对BROS结构进行表征,结果表明,该寡糖由1个葡萄糖(α-D-Glcp)和7个果糖(β-D-Fru组成,残基间以→2)Fruf-(1→链接,分子末端链接为a-Glcp-(1→,→2)-β-D-Fruf推出BROS的结构式为:β-D-Fruf1-(2→1)-β-D-Fruf2-(2→1)-β-D-Fruf3-(2→ 1)-β-D-Fruf4-(2→1)-β -D-Fruf5-(2→1)-β-D-Fruf6-(2→ 1)-β-D-Fruf7-(2→ 1)-a-D-Glcp. 相似文献
3.
A new flavonol ologosaccharide,quercetin-3-O-[β-D-xylopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside-3′-O-β-D-glucopyranoside, named aesculfavoside was inolated from Aesculus chinensis.It′s structure was elucidatede by spectra FAB-MS,1D NMR and 2D NMR including ^1H NMR,^13C NMR,HMQC and HMBC techniques. 相似文献
4.
单2-O-和单6-O-(2-羟丙基)-β-环糊精结构表征 总被引:1,自引:0,他引:1
以β-环糊精和环氧丙烷为原料,分别在1.5%、30%(m/m)NaOH水溶液和β-环糊精与环氧丙烷的摩尔比为1∶7的条件下合成了2-O-(2-羟丙基)-β-环糊精和6-O-(2-羟丙基)-β-环糊精,以异丙醇-水-氨水(6∶3∶1,V/V)为洗脱液,分别经柱色谱分离得到单2-O-(2-羟丙基)-β-环糊精和单6-O-(2-羟丙基)-β-环糊精,并利用DSC,ESI-MS,1HNMR,13C NMR对单2-O-(2-羟丙基)-β-环糊精、单6-O-(2-羟丙基)-β-环糊精的结构进行了系统研究。结果发现,2-O-(2-羟丙基)-β-环糊精的热稳定性要高于6-O-(2-羟丙基)-β-环糊精。13C NMR结果表明,当β-环糊精2-位上引入取代基后,会影响2-位、1-位、3-位碳化学位移的变化,当β-环糊精6-位上引入取代基后,会影响6-位、5-位碳化学位移的变化,因此,可以用13C NMR方法有效地识别2-HP-β-CD取代基的位置。 相似文献
5.
FAN Gao-Jun HE Zhi-ShengShanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai ChinaWU Hou-Ming XU Jing-FeiState Key Laboratory of Bioorganic Natural Products Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai China 《中国化学》1997,15(5):431-437
Four new triterpenoid saponins were isolated from the roots of Adina rubella Hance. They were characterized as adinaic acid 3β-O-[α-L-rhamnopyranosyl(l→2)-β-D-glucopyranosyl(l→2)-β-D-glucurono-pyranoside-6-O-methyl ester]-28-O-β-D)-glucopyranoside, adinaic acid 3β-O-[α-L-rham-nopyranosyl(l→2)-β-D-glucopyranosyl(l→2)-β-D-glucuronopyranoside-6-O-butyl ester]-28-O-β-D-glu-copyranoside, adinaic acid 3β-O-[β-D-glucopyranosyl(l→2)-β-D-glucopyranosyl]-(28→1)-β-D-gluco-pyranosyl(l→6)-β-D-glucopyranosyl ester, 27-hydroxyursolic acid 3β-O-[α-L-rhamnopyranosyl (l→2)-β-O-glucopyranosyl(l→2)-β-D)-glucuronopyranoside-6-O-methyl ester]-28-O-β-D)-glucopyranoside. Their structures were elucidated by spectral methods, especially with the aid of 2D NMR techniques. Their complete assignments of the 1H and 13C NMR signals were carried out. 相似文献
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7.
两头尖的化学成分研究(Ⅰ) 总被引:4,自引:0,他引:4
采用硅胶柱色谱和高效液相色谱等方法,对两头尖的化学成分进行了研究,从中分离得到两个化合物,经化学及IR,ESI-MS,^1H NMR,^13C NMR,DEPT,HMQC,HMBC,GCOSY,TOCSY等谱学分析鉴定其结构分别为:3-O-α-Larabinopyranosyl(1→3)-α-L-dmmnopyranosyl(1→2)[β-D-glucopymnosyl(1→4)]-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside(1),3-O-β-D-glucopyranosyl(1→4)-β-D-glucopymnosyl(1→3)-α-L-rhammnopyranosyl(1→2)-α-L-arabinopyranosyl oleanolic acid 28-O-α-L-rhammnopymnosyl(1→4)-β-D-glucopyranosyl(1→6)-β-glucopymmside(2),该两个化合物为新化合物,分别命名为:多被银莲花皂苷16(Raddeanoside 16)和多被银莲花皂苷17(Baddeanoside 17). 相似文献
8.
Three new 27-nor-triterpenoid saponias named rubenorside A (1),rubenorside B(2) and rubenorside C (3) were isolated from the roots of Adina rubella.Their structures were characienzed as pyrocincholic acid 3β-O-α-L-rhamnopyranosyl(28→1 )-β-D-glucopyranosyl ester (1),pyrocinchohe acid 3β-O-β-D-glucopyranosyl(1→2)-β-D-fucopyranosyl(28→1)-β-D-glucopyranosyl(1→6)-β-D-glico-pyranosyl ester (2) and pyrocincholic acid 3β-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranosyl(28→1)β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl ester () by spectral methods,especially 2D NMR experiments. 相似文献
9.
Two new phenylpropanoid glycosides,9-O-[6-O-acetyl-β-D-glucopyranosyl]-4-hydroxycinnamic acid(1) and 8-O-β-D-glucopyranosyl -(R)-(+)-3,4,8-trihydroxy methyl phenylpropionate(2) were isolated from the 80%EtOH extract of the roots of Sanguisorba officinalis.Their structures were characterized by spectroscopic analysis and chemical method,including 1D NMR,2D NMR,and HR-ESI-MS.Compounds 1 and 2 exhibited the moderate antimicrobial activities against all Gram-positive and Gram-negative bacteria tested. 相似文献
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Two new diterpene rhamnosides, mimosasides B and C (1, 2) were isolated together with mimosaside A (3), a known diterpene rhamnoside (4), four known flavones (5-8), five known flavanones (9-13), and four known chalcones (14-17) from the leaves and twigs of a Brazilian medicinal plant, Mimosa hostilis. 相似文献
12.
Morikawa T Xu F Ninomiya K Matsuda H Yoshikawa M 《Chemical & pharmaceutical bulletin》2004,52(4):494-497
New dolabellane-type diterpene alkaloids, nigellamines A(3), A(4), A(5), and C, were isolated from the methanolic extract of an Egyptian medicinal food, black cumin (the seeds of Nigella sativa). Their absolute configurations were determined on the basis of chemical and physicochemical evidence. Nigellamines were found to lower triglyceride levels in primary cultured mouse hepatocytes, and in particular, the activity of nigellamine A(5) was equivalent to that of the hypolipidemic agent, clofibrate. 相似文献
13.
Subashini Raman Vikneswaran Murugaiyah Thaigarajan Parumasivam 《Molecules (Basel, Switzerland)》2022,27(19)
Andrographis paniculata is a well-known Asian medicinal plant with a major phytoconstituent of diterpene lactones, such as andrographolide, 14-deoxyandrographolide, and neoandrographolide. A World Health Organization (WHO) monograph on selected medicinal plants showed that A. paniculata extracts and its major diterpene lactones have promising anti-inflammatory, antidiabetic, antimalarial, anticancer, antifungal, antibacterial, antioxidant, and hypoglycemic activities. However, these active phytochemicals have poor water solubility and bioavailability when delivered in a conventional dosage form. These biological barriers can be mitigated if the extract or isolated compound are delivered as nanoparticles. This review discusses existing studies and marketed products of A. paniculata in solid, liquid, semi-solid, and gaseous dosage forms, either as an extract or isolated pure compounds, as well as their deficits in reaching maximum bioavailability. The pharmaceutics and pharmacological activity of A. paniculata as a nano-delivery system are also discussed. 相似文献
14.
Five new C19 diterpene alkaloids, leucanthumsines A ( 1 ), B ( 2 ), C ( 3 ), D ( 4 ), and E ( 5 ), were isolated from the Chinese medicinal herb Aconitum sungpanense var. leucanthum, together with the known C19 diterpene alkaloids pseudaconine, neoline, 1‐O‐methyldelphisine, crassicaudine, chasmanine, talatisamine, indaconitine, ezochansmanine, and leueantine D. The structures of these new alkaloids were elucidated by HR‐MS and advanced NMR methods, including 1H‐ and 13C‐NMR (DEPT), 1H,1H‐COSY, HMQC, and HMBC experiments. 相似文献
15.
Naoki Mori Chiaki Mase Hidenori Watanabe Hirosato Takikawa 《Tetrahedron letters》2018,59(26):2600-2603
Pseudolaric acids A (1) and B (2) are diterpene acids isolated from the root bark of Pseudolarix kaempferi as the main biologically active constituents of tujinpi, a traditional Chinese medicinal herb. Studies toward the total synthesis of 2 are described. The unusual trans-fused [5–7] ring system in the core structure of 2 was successfully synthesized via Dieckmann condensation. 相似文献
16.
Background
Triptolide is a diterpene triepoxide from the Chinese medicinal plant Tripterygium wilfordii Hook F., with known anti-inflammatory, immunosuppressive and anti-cancer properties. 相似文献17.
18.
Zou J Pan L Li Q Zhao J Pu J Yao P Gong N Lu Y Kondratyuk TP Pezzuto JM Fong HH Zhang H Sun H 《Organic letters》2011,13(6):1406-1409
From the medicinal plant Isodon rubescens, we isolated two novel diterpenes, rubesanolides A (1) and B (2). The compounds contain a unique β-lactone subgroup. This is the first discovery for a natural diterpene having rings A, B, and C in chair, boat, and twist-chair conformations, respectively. The structures were elucidated by analysis of spectroscopic data, and the absolute configuration of 1 was determined by X-ray diffraction. 相似文献
19.
藏药"帕朱胶囊"中微量元素及重金属元素分析 总被引:1,自引:0,他引:1
为探讨藏药“帕朱胶囊”中微量元素与其治疗胃病的相关性,以及监测藏药中的重金属含量,采用原子吸收分光光度法,对帕朱胶囊中的11种元素进行了测定。结果表明,帕朱胶囊中Fe元素含量较高,并含有Cu、Zn、Mn、Se等与治疗胃病直接相关的微量元素,重金属元素Pb、As、Hg含量不超标。为研究传统藏药帕朱胶囊的药效物质基础和安全使用,提供了科学依据。 相似文献
20.
Three new tetracyclic diterpenes were isolated from the chloroform-soluble extract of Euphorbia villosa, together with one new and one known lathyrane diterpene. The structures were elucidated by means of various spectroscopic methods, including HREI-MS, HRFAB-MS, UV, and 1D and 2D NMR techniques. Spectral analyses revealed that two of the tetracyclic compounds contain the rare 5-6-6-4 fused ring system, while the third has a 5-6-7-3 fused diterpene core. Such diterpene skeletons have previously been found only in euphoractines A-E isolated from Euphorbia micractina. As a new structural feature, the diterpene framework described here has a C-2 epimer configuration. The new lathyrane diterpene is a diester of a hitherto unknown polyfunctional parent alcohol. 相似文献