共查询到20条相似文献,搜索用时 15 毫秒
1.
U. T. Teshebaeva A. N. Sultankhodzhaev A. A. Nishanov 《Chemistry of Natural Compounds》1999,35(6):659-660
A new alkaloid called akiramidine is isolated from the aerial part ofAconitum kirinense. The structure 6β,14α,16β-trimethoxy-1α,4β,8β-trihydroxy-N-ethylaconitane is proposed based on spectral data and confirmed
by chemical transformation from akiramine.
Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 774–776, November–December, 1999. 相似文献
2.
Another new cardenolide glycoside has been isolated from the plantCheiranthus allioni Hort., and has been named glucocheiranthoside. Its chemical structure has been established as 3β-(4′-O-β-D-glucopyranosyl-β-D-gulmoethylpyranosyloxy)-14-hydroxy-19-oxo-5β,14β-card-20(22)-enolide.
State Scientific Center for Drugs, Ukraine, 310085, Kharkov, USSR. ul. Astronomicheskaya, 33. Translated from Khimiya Prirodnykh
Soedinenii, No. 2, pp. 269–271, March–April, 1994. 相似文献
3.
U. A. Baltaev 《Chemistry of Natural Compounds》1991,27(6):712-713
A new ecdysteroid (rhapisterone B) has been isolated from the seeds ofRhaponticum cathamoides (Willd.) Iljin. (familyCompositae). It has been shown that it is 2β, 3β, 11α, 14α, 20R, 24ξ-hexahydroxy-5β-cholest-7-en-6-one.
Institute of the Chemistry of Plant Substances, Uzbek Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii,
No. 6, pp. 806–808, November–December, 1991. 相似文献
4.
A new withasteroid — physangulide — has been isolated from the leaves ofPhysalis angulata L. It has been shown that physangulide is the first natural 22S-withanolide. Its structure has been determined as 3β,4β,20,24,25-pentahydroxy-1-oxo-5β,6β-epoxy-20R,22S,24S,25R-withanolide.
Its1H and13C NMR spectra, confirming this interpretation, are given.
Institute of the Chemistry of Plant Substances, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh
Soedinenii, No. 3, pp. 366–371, May–June, 1990. 相似文献
5.
The lactone 20R-25-norcycloartan-3β,6α,16β-triol-20,24-olide was synthesized from cyclosiversigenin.
Presented at the 1st International Symposium on Edible Plant Resources and the Bioactive Ingredients, Xinjiang, China, July
25–27, 2008.
Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 324–327, May–June, 2009. 相似文献
6.
R. Zh. Karimov R. U. Umarova Z. Saatov M. G. Levkovich N. D. Abdullaev 《Chemistry of Natural Compounds》1998,34(5):609-612
Two new triterpene glycosides of the cycloartane series, which have been called cyclostipulosides A and B, have been isolated
in the individual form from the roots ofTragacantha stipulosa Boviss. Their structures have been established by physicochemical methods. Cyclostipuloside A is 24R-cycloartane-3β,6α,16β,24,25-pentaol
16-O-β-D-glucopyranoside 3-O-β-D-xylopyranoside, and cyclostipuloside B is 24R-cycloartane-3β,6α,16β,24,25-pentaol 6-O-α-L-arabinopyranoside 16-O-β-D-glucopyranoside 3-O-β-D-xylopyranoside. By the acid hydrolysis of cyclostipulosides A and B we have obtained the new glycoside
24R-cycloartane-3β,6α,16β,24,25-pentaol 16-O-β-D-glucopyranoside.
Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (371) 120
64 75. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 670–674, September–October, 1998. 相似文献
7.
I. A. Sukhina R. P. Mamedova M. A. Agzamova M. I. Isaev 《Chemistry of Natural Compounds》2007,43(2):159-161
The two trisdesmoside cycloartane glycosides astragaloside VII and cyclotrisectoside were isolated from Astragalus dissectus (Leguminosae) and identified. The latter was 20R,25-epoxy-24S-cycloartan-3β,6α,16β,24-tetraol 3-O-β-D-xylopyranoside-6,24-di-O-β-D-glucopyranoside and was a new natural compound.
Presented at the Sixth International Symposium on the Chemistry of Natural Compounds (SCNC, Turkey, Ankara, 28–29 June 2005).
__________
Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 132–134, March–April, 2007. 相似文献
8.
Ya. L. Garazd E. M. Kornienko L. N. Maloshtan M. M. Garazd V. P. Khilya 《Chemistry of Natural Compounds》2005,41(5):508-512
3,4-Cyclocondensed coumarin O-glycopyranosides containing glucose, galactose, xylose, and arabinose were synthesized by condensation
of potassium salts of hydroxycoumarins and acetobromosugars. 7-(β-D-Galactopyranosyloxy)-2,3-dihydrocyclopenta[c]chromen-4-one,
3-(β-D-xylopyranosyloxy)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one, and 3-(α-D-arabinopyranosyloxy)benzo[c]chromen-6-one exhibited
distinct anticoagulant activity.
__________
Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 416–419, September–October, 2005. 相似文献
9.
Chunyi Jiang Yu Feng Xiaotong Huang Yechun Xu Yaping Zhang Naiming Zhou Xu Shen Kaixian Chen Hualiang Jiang Dongxiang Liu 《Analytical and bioanalytical chemistry》2010,396(5):1745-1754
Aβ1–42 is the proteolytic cleavage product of cleavage of the amyloid precursor protein by β- and γ-secretases. The aggregation
of Aβ1–42 plays a causative role in the development of Alzheimer’s disease. To lock Aβ1–42 in a homogenous state, we embedded the Aβ1–42 sequence in an unstructured region of Bcl-xL. Both the N-terminus and the C-terminus of Aβ1–42 were constrained in the disordered region, whereas the conjunction did not introduce any folding to Aβ1–42 but maintained the sequence as a monomer in solution. With Bcl-xL-Aβ42, we developed an enzyme-linked immunosorbent assay to compare the affinity of compounds for monomeric Aβ1–42. Bcl-xL-Aβ42 was coated on a microplate and this was followed by incubation with different concentrations of compounds. Compounds binding
to Leu17-Val24 of Aβ1–42 inhibited the interaction between Bcl-xL-Aβ42 and antibody 4G8. The method can not only reproduce the activities of the reported Aβ1–42 inhibitors such as dopamine, tannin, and morin but can also differentiate decoy compounds that do not bind to Aβ1–42. Remarkably, using this method, we discovered a new inhibitor that binds to monomeric Aβ1–42 and inhibits Aβ1–42 fibril formation. As the structure of Bcl-xL-Aβ42 monomer is stable in solution, the assay could be adapted for high-throughput screening with a series of antibodies that
bind the different epitopes of Aβ1–42. In addition, the monomeric form of the Aβ1–42 sequence in Bcl-xL-Aβ42 would also facilitate the identification of Aβ1–42 binding partners by coimmunoprecipitation, cocrystallization, surface plasmon resonance technology, or the assay as described
here. 相似文献
10.
The new cycloartane glycoside cycloorbicoside D, which has the structure 23ξ,24ξ-cycloartan-3β6α,16β,23,24,25-hexaol 3-O-β-D-xylopyranoside,
was isolated from the aerial part of Astragalus orbiculatus Ledeb. (Leguminosae).
__________
Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 345–346, July–August, 2005. 相似文献
11.
A. A. Shashkov V. I. Grishkovets O. Ya. Tsvetkov V. Ya. Chirva 《Chemistry of Natural Compounds》1993,29(4):502-508
The previously known glycosides 3-O-α-L-arabinopyranosyl-28-O-[α-L-rhamnopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl]hederagenin
and 3-O-[α-L-rhamnopyranosyl-(1→2)-O-α-L-arabinopyranosyl]-28-O-[α-L-rhamnopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl]hederagenin
and the new triterpene glycoside tauroside St-H1 — 3-O-β-D-glucopyransyl-28-O-[α-L-rhamnopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl]hederagenin — have
been isolated from the stems ofHedera taurica Carr.
M. V. Frunze Simferopol' State University. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 571–579, July–August,
1993. 相似文献
12.
The structure of the new cycloartane glycoside cyclomacroside D, which was isolated from Astragalus macropus Bunge (Leguminosae) and is 24R-cycloartan-1α,3β,7β,24,25-pentaol 3-O-α-L-rhamnopyranoside–24-O-β-D-xylopyranoside, was proved.
Presented at the 7th International Symposium on the Chemistry of Natural Compounds (SCNC, Tashkent, Uzbekistan, October 16–18,
2007).
Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 48–50, January–February, 2009. 相似文献
13.
M. Kh. Dzhukharova Z. Saatov N. D. Abdullaev N. K. Abubakirov 《Chemistry of Natural Compounds》1994,30(6):680-683
A new brahuisterone glycoside — silenoside F — has been isolated from the epigeal part ofSilene brahuica Bois. (fam. Caryophyllaceae). Its structure has been established by an analysis of spectral characteristics: 3β,5,14α,22R,25-pentahydroxy-5β-cholest-6-one
3-O-β-D-glucopyranoside.
Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89
14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 734–737, November–December, 1994. 相似文献
14.
G. V. Shevchuk Yu. S. Vollerner A. S. Shashkov M. B. Gorovits V. Ya. Chirva 《Chemistry of Natural Compounds》1991,27(6):706-711
Two new glycosides which have been called nolinofurosides G(I) and H(III), have been isolated from the leaves ofNolina microcarpa. Nolinofuroside G is the sodium salt of 26-β-D-glucofuranosyloxy-(25S)-furost-5,20(22)-diene-1β, 3β-diol 1-sulfate, and nolinofuroside
H is the sodium salt of 1-β-D-fucopyranosyloxy-26-β-D-glucopyranosyloxy-(25S)-furost-5,20(22)-dinen-1β-3β-ol 3-sulfate.
M. V. Frunze Simferopol' State University. Institute of the Chemistry of Plant Substances, Uzbek. Academy of Sciences, Tashkent.
Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 801–806, November–December, 1991. 相似文献
15.
Nine compounds including six cycloartane glycosides cyclosieversiosides A, B, F, G, and H and astrasieversianin IX; β-sitosterol, β-sitosterol β-D-glucopyranoside, and D-3-O-methyl-chiro-inositol were isolated and identified from roots of Astragalus sieversianus Pall. (Leguminosae) growing in the Republic of Kyrgyzstan.
Presented at the 6th International Symposium on the Chemistry of Natural Compounds (SCNC, Ankara, Turkey, June 28–29, 2005.
__________
Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 253–256, May–June, 2008. 相似文献
16.
A. É. Timbekova M. F. Larin M. R. Yagudaev N. K. Abubakirov 《Chemistry of Natural Compounds》1989,25(5):573-576
A new triterpene glycoside — medicoside H — has been isolated from the roots ofMedicago sativa L. (Fabaceae), and on the basis of chemical transformations and spectral characteristics its structure has been established
as medicagenic acid 3-O-β-D-glucopyranoside 28-O-[O-α-L-rhamnopyronosyl-(1 → 2)-β-L-arabino-pyranoside].
Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh
Soedinenii, No. 5, pp. 673–677, September–October, 1989. 相似文献
17.
G. V. Shevchuk Yu. S. Vollerner A. S. Shashkov V. Ya. Chirva 《Chemistry of Natural Compounds》1991,27(5):597-603
In addition to the know steroid sapogenin (25S)-ruscogenin (I), three new glycosides have been isolated from the leaves ofNolina microcarpa S. Wats. (family Dracaenacea), and the following structures are suggested for them: (25S)-spirost-5-ene-1β,3β-diol 1-O-β-D-fucopyranoside
(nolinospiroside C, II), (25S)-furost-5-ene-1β,3β,22α,26-tetraol 1-O-β-D-fucopyranoside (nolinofuroside A, III), and (25S)-furost-5-ene-1β,
3β, 22α, 26-tetraol 1-O-β-D-fucopyranoside 26-O-β-D-glucopyranoside (nolinofuroside C, V).
M. V. Frunze Simferopol' State University. Institute of Chemistry of Plant Substances, Uzbek Academy of Sciences, Tashkent.
Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 672–678, September–October, 1991. 相似文献
18.
The regio- and stereoselective synthesis of ginsenoside Rh2, which possesses antitumoral activity, has been effected by the glycosylation of 12β-acetoxydammar-24-ene-3β,20(S)-diol.
Condensation with α-acetobromoglucose was carried out in the presence of silver oxide in dichloroethane at room temperature,
and the yield of the desired glycoside amounted to 50%. A method for the selective protection of the C-12-OH group of dammar-24-ene-3β,12β,20(S)-triol
[20(S)-protopanaxadiol] has been proposed.
Pacific Ocean Institute of Bioorganic Chemistry, Far Eastern Branch, USSR Academy of Sciences, Vladivostok. Translated from
Khimiya Prirodnykh Soedinenii, Vol. 6, pp. 813–816, November–December, 1989. 相似文献
19.
M. A. Khodzhaeva 《Chemistry of Natural Compounds》1994,30(2):162-165
The structures of the glucofructans GFAS-B3 and GFAS-I have been established on the basis of the results of periodate oxidation,
methylation, and IR and13C NMR spectroscopies. It has been shown that the glucofructans studied are compounds containing both inulin, (2→1)β, and levan,
(2→6)β, glycosidic bonds.
Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, FAX (3712) 62
73 48. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 179–183, March–April, 1994. 相似文献
20.
Maksim Ionov Barbara Klajnert Konstantinos Gardikis Sophia Hatziantoniou Bartlomiej Palecz Bakhtiyar Salakhutdinov Josep Cladera Maria Zamaraeva Costas Demetzos Maria Bryszewska 《Journal of Thermal Analysis and Calorimetry》2010,99(3):741-747
To investigate the molecular interaction of amyloid beta peptides Aβ1–28 or Aβ25–40 with model lipid membranes differential scanning calorimetry (DSC) and DPH and TMA DPH fluorescence anisotropy approaches
were used. The main transition temperature (T
m) and enthalpy change (ΔH) of model lipid membranes composed of DMPC/DPPG on addition of Aβ25–40 or Aβ25–40 at 10:1 (w/w) phospholipid/peptide ratio either non-aggregated or previously aggregated were examined. The effect of Aβ1–28 and Aβ25–40 on the membrane fluidity of liposomes made of DMPC/DPPG (98:2 w/w) was determined by fluorescence anisotropy of incorporated
DPH and TMA DPH. The results of this study provide information that Aβ1–28 preferentially interacts with the hydrophilic part of the model membranes, while Aβ25–40 rather locates itself in the hydrophobic core of the bilayer where it reduces the order of the phospholipids packing. 相似文献