Doppler spectroscopy of blood in vivo under the action of low-intensity laser radiation

The rate of microcirculation of blood in human skin is studied in vivo in the normal state and in the presence of cardiovascular diseases. It is shown experimentally that low-intensity laser radiation affects the rheological characteristics of erythrocytes. To explain the results obtained, a model for calculating the heating of blood in capillaries under the action of low-intensity laser radiation is proposed.     

Direct simulation monte carlo of pulsed laser ablation of metals with clusterization processes in vapor

A mathematical model is proposed to describe laser ablation of metals in vacuum under the action of nanosecond laser pulses of moderate intensity taking into account the processes of cluster formation and decay in the vapor cloud. To describe the laser radiation absorption and metal heating, the thermal model based on the unsteady one-dimensional heat equation with a volume heat source is used, and the method of statistical modelling is employed for modelling vapor expansion and the processes of cluster formation. The efficiency of the proposed complex model is considered by the example of pulsed laser ablation of a niobium target. The work was supported financially by INTAS (grant No. 03-51-5208).     

Features of neodymium laser epilation

The efficiency and features of the use of the Nd:YAG laser for epilation in comparison with ruby, alexandrite, diode lasers and a broadband light source were studied. Procedures for calculating the temperature distribution of the hair follicle over the entire depth of its position in the skin and temperatures of undesirable heating of surrounding skin regions under exposure to Nd:YAG laser radiation were developed. The heating temperature of hair follicles with black, brown, and light hair was calculated. The heating temperature of follicles of biological tissues for patients with light, swarthy, and dark skin was calculated. The ranges of the neodymium laser applicability to hair and skin colors during epilation procedures were determined. The ways of optimization of the output radiation parameters (pulse energy and duration, light spot sizes) for removing variously colored hair of patients with various skin phototypes were directed. The ways of epilation technology improvement (active skin cooling, injection of special dyes into hair follicles, and others) were proposed.     

The effect of blood flow on the laser heating of skin

The dynamics of the action of laser radiation on skin is modeled taking into account the changes in blood flow. It is shown that a change in the blood flow rate significantly affects the character of laser heating, leading to the formation of a temperature peak at the initial stage of the heating.     

Numerical Simulation Optimization of Selective Heating of Blood Vessels in “Port-Wine Stains” under Laser Irradiation in Various Modes

Numerical simulation of blood vessel heating is used to select the most efficient and safe methods of laser treatment of “port-wine stains”. Selective heating under radiation is calculated for a 980-nm diode laser, a Nd:YAG laser, a copper vapor laser (CVL), and a pulsed dye laser (PDL). The energy exposure range (fluence), the diameter and depth of vessels, at which their selective heating to the coagulation temperature is possible, are determined.     

Temperature field dynamics inside a blood vessel subjected to the action of laser radiation

The dynamics of the temperature field in a subcutaneous blood vessel subjected to laser radiation is calculated by a method similar to that used previously but taking into account the heat exchange at the interface between the bloodstream and surrounding tissues. The distribution function of heat sources is determined based on the solution of the problem of diffraction of electromagnetic radiation from a circular cylinder. Regimes of irradiation of skin required for blocking the bloodstream under corresponding medical indications are modeled. In this case, the optimal exposure times depend on the vessel diameters and, for radiation at a wavelength of 530 nm, vary from tens to hundreds of microseconds.     

Effect of the initial temperature on the threshold of laser initiation of pentaerythritol tetranitrate seeded with aluminum nanoparticles

The effect of temperature on the threshold of explosive decomposition of pentaerythritol tetranitrate samples with a density of ρ = 1.73 g/cm³ containing 0.1 wt % 100- to 120-nm aluminum particles under the action of laser pulses (λ = 1.06 μm, τ = 20 ns) is examined. A model capable of describing the experimental results is proposed, according to which the explosive decomposition of the samples is associated with the absorption of laser radiation by structural defects of pentaerythritol tetranitrate and aluminum nanoparticles. It is demonstrated that, at 300 K, explosion initiation is largely determined by the heating of aluminum nanoparticles with the formation of chemical decomposition kernels nearby.     

Acoustoelectronic interaction in InGaAsP/InP laser heterostructures

The dynamics of change in the spectral characteristics of the emission from a laser heterostructure due to an alternating strain induced by a surface acoustic wave is investigated. The spectral distributions of the laser radiation intensities are analyzed with the aim of elucidating the mechanisms responsible for the interactions occurring in the laser heterostructure. A model is proposed for describing the experimental data, and their theoretical analysis is performed. It is demonstrated that the acoustoelectronic interaction is dominant under the action of surface waves. The deviation of the observed frequency modulation of radiation is determined from a comparison of the theoretical calculations with experimental data.     

Heat-transfer processes upon laser heating of inert-matrix-hosted inclusions

A model to describe the heating of metal inclusions in inert media by a laser radiation pulse with allowance for the heat-transfer and melting processes in the matrix and inclusion materials is proposed. The time regularities of the heating of the matrix and inclusions were examined, and the dependences of the maximum temperature on the particle surface on the laser pulse energy density and on the particle radius were obtained. Approximate formulae for the maximum heating temperature and for the radius of most heated particles are proposed. We show that melting processes result in a reduction of the maximum heating temperature and in an insignificant variation of the radius of most heated particles.     

Laser annealing of silica glass with ion-synthesized copper nanoparticles

The action of KrF excimer laser radiation on the composite material consisting of the silica glass with copper nanoparticles is investigated as a function of the number of nanosecond laser pulses. Metal nanoparticles are synthesized by ion implantation. It is established using optical reflectance measurements of composite layers that, at the initial stage, the irradiation leads to the fragmentation of the largest nanoparticles. Then, after irradiation by several pulses, the particles become larger due to the heating of the glass. The laser treatment for a longer time (several tens and hundreds of pulses) results in the dissociation of nanoparticles into small clusters and individual atoms. The mechanisms responsible for the modification of the composite material under high-power laser radiation are discussed.     

Local phase-structure modification inside of lithium silicate glass by combined double-wavelength laser action

The process of local structure modification inside of lithium silicate glass under the combined laser action of two different wavelengths is considered. The first step is laser irradiation of ultrashort laser pulses with 532 nm wavelength, which is used to create of nucleation centers inside of the optically transparent glass. The crystallization of the structural modification areas was carried out by a photothermal action of CO₂ laser radiation with a 10.6 μm wavelength. The range of crystallization temperatures was defined and the kinetics of the phase transformations of the modified regions inside of the glass were studied. Duration of crystallization was about 10 min with a slow heating and 25 s at the fast heating to crystallization temperature.     

Localized surface plasmon polaritons and nonlinear overcoming of the diffraction optical limit

Experimental results on the formation of ordered structures on the surface and in the near-surface layer of condensed media under the action of linearly polarized laser radiation pulses are analyzed. The formation of subdiffraction nanostructure gratings with anomalous orientation is discussed in the context of the universal polariton model. A physical model of the formation of anomalous structure gratings with periods much less than the laser radiation wavelength is proposed and experimentally verified. The model is based on excitation and mutual interference of channel (wedge) surface plasmon polaritons.     

A real-time infrared radiation imaging simulation method of aircraft skin with aerodynamic heating effect

Real-time infrared radiation simulation technology can provide effective support for rapid design and evaluation of a system which integrates infrared imaging technology. Considering the aerodynamic heating effect, this paper presents a real-time infrared radiation characteristic simulation method of aircraft skin based on the panel element method, which can help to assess the infrared radiation impacts of different environment factors and materials. A 3-D model of an aircraft was established and its surface was divided into different parts and panel element meshes to attach material properties. For each mesh, its heat exchange equation is solved so as to obtain the whole skin’s temperature and infrared radiation distribution. The simulation results reveal the influence of different factors on the skin surface radiation, including environmental radiation, aerodynamic heating and material properties. And the credibility and efficiency of the proposed aerodynamic heating simulation method were confirmed by comparing to the CFD simulation results.     

Laser-induced generation of surface periodic structures in media with nonlinear diffusion

A model of fast formation of high-contrast periodic structure appearing on a semiconductor surface under action of laser radiation is proposed. The process of growing a surface structure due to the interaction surface plasmon- polaritons excited on nonequilibrium electrons with incident laser radiation are considered in the framework of a medium with nonlinear diffusion of nonequilibrium carriers (defects). A resonance effect of superfast pico- and subpicosecond amplification of the plasmon-polariton structure generated on the surface, the realization of which can result in a high-contrast defect lattice.     

Simulation of the thermal processes induced by action of laser radiation on organic media

A mathematical model is proposed for calculation of the hyperthymia of a multilayer biological structure under the action of laser radiation. For the in vivo case, the dependences of the temperature field on the refractive index and absorption coefficient of the biological tissue under study (epidermis, the upper derma layer, the lower derma layer, blood and its corpuscles) are determined. The obtained quantitative estimates can be used to predict the changes in the optical properties of the biological structure that are caused by the biophysical, biochemical, and physiological processes during the action of a nonpolarized monochromatic radiation flow on the structure surface.     

Modeling of the processes of laser-nanoparticle interaction taking into account temperature dependences of parameters

Absorption, electron-phonon coupling and heating of nanoparticles (NPs) under action of short laser pulses on NPs and their cooling after the end of laser action usually has nonlinear character. Nonlinear electron-phonon coupling under action of pico- and femtosecond pulses on metal NPs depends on electron and lattice parameters. Optical (absorption, scattering, extinction) and thermo-physical (coefficient of thermal conductivity, heat capacity, etc.) parameters of different materials of NPs (metals, oxides, semiconductors, etc.) and environments (water, liquids, dielectrics, etc.) depend on temperature and determine nonlinear dynamics of NPs heating and cooling. It is very important to take into account the temperature dependence of optical and thermophysical parameters of NPs and surrounding media under investigation of absorption of laser radiation, electron-phonon coupling, nanoparticle (NP) heating, heat transfer and its cooling after the end of laser pulse action. Theoretical modeling of the processes of laser-NP interaction taking into account temperature dependences of parameters of NPs and environments was carried out. Influence of temperature dependences of these parameters on values and dynamics of the processes is determined.     

A physical model of laser-assisted blocking of blood flow: II. Pulse modulation of radiation

A method for the calculation of blocking of blood flow upon treatment of vessel pathologies by laser irradiation at a wavelength of 530 nm are considered. The model is based on the assumption that blood-vessel occlusion is a consequence of preceding photothermal coagulation of internal layers of the vessel wall. The irradiation regimes are determined that provide homogeneous and highly efficient coagulation of the vessel wall under irradiation of tissues by series of short radiation pulses.     

Generation of low-frequency radiation by dense hot plasma under pondermotive action of a short laser pulse

The theory of the generation of low-frequency radiation under the pondermotive action of a femtosecond laser pulse on dense hot plasma is developed. It is shown that, at fairly high plasma temperatures, when electron-electron collisions are rare and the low-frequency field is excited under conditions of the anomalous skin effect, the generation efficiency can be close to maximal. The optimal generation conditions are achieved if the carrier frequency of the laser pulse is close to the plasma frequency and the pulse is tightly focused. Under irradiation by pulses with durations of tens to hundreds femtoseconds, terahertz radiation is generated in a broad angular range.     

Acousto-electron interaction in InGaAsP/InP laser heterostructures

The frequency modulation of the heterolaser radiation under the ultrasonic strain has been found out. The dynamic and static analysis of the spectral parameters change caused by the alternating strain has been fulfilled. A model is proposed for describing the experimental data, and their theoretical analysis is performed. It is demonstrated that the acousto-electron interaction is dominant under the action of surface waves in InGaAsP/InP laser heterostructures.