Global well-posedness and asymptotic stabilization for chemotaxis system with signal-dependent sensitivity

A fully parabolic chemotaxis system

$u_t=\mathrm{\Delta }u?\mathrm{?}?(u\chi (v)\mathrm{?}v),v_t=\mathrm{\Delta }v?v+u,$

in a smooth bounded domain $\mathrm{\Omega }?{\mathbb{R}}^N$, $N\ge 2$ with homogeneous Neumann boundary conditions is considered, where the non-negative chemotactic sensitivity function χ satisfies $\chi (v)\le \mu {(a+v)}^{?k}$, for some $a\ge 0$ and $k\ge 1$. It is shown that a novel type of weight function can be applied to a weighted energy estimate for $k>1$. Consequently, the range of μ for the global existence and uniform boundedness of classical solutions established by Mizukami and Yokota [23] is enlarged. Moreover, under a convexity assumption on Ω, an asymptotic Lyapunov functional is obtained and used to establish the asymptotic stability of spatially homogeneous equilibrium solutions for $k\ge 1$ under a smallness assumption on μ. In particular, when $\chi (v)=\mu /v$ and $N<8$, it is shown that the spatially homogeneous steady state is a global attractor whenever $\mu \le 1/2$.     

Boundedness in a fully parabolic chemotaxis‐consumption system with nonlinear diffusion and sensitivity,and logistic source

In this paper we study the zero‐flux chemotaxis‐system Ω being a convex smooth and bounded domain of , , and where , and . For any the chemotactic sensitivity function is assumed to behave as the prototype , with and . We prove that for nonnegative and sufficiently regular initial data and , the corresponding initial‐boundary value problem admits a unique globally bounded classical solution provided μ is large enough.     

A new approach toward boundedness in a two‐dimensional parabolic chemotaxis system with singular sensitivity

We consider the parabolic chemotaxis model in a smooth, bounded, convex two‐dimensional domain and show global existence and boundedness of solutions for χ∈(0,χ₀) for some χ₀>1, thereby proving that the value χ = 1 is not critical in this regard. Our main tool is consideration of the energy functional for a > 0, b≥0, where using nonzero values of b appears to be new in this context. Copyright © 2015 John Wiley & Sons, Ltd.     

Boundedness in chemotaxis systems with rotational flux terms

We consider the chemotaxis system with rotation under no‐flux boundary conditions in the bounded domain , . Here the matrix‐valued function fulfills () for all with some nondecreasing function S₀ and is a nonnegative function with for all . Moreover, f satisfies for all with nondecreasing function f₀. It is shown that for the nonnegative initial data and with , if at least one of the following assumptions holds:

• ,
• , and ,
• ,

then the corresponding initial‐boundary value problem possesses a unique global classical solution that is uniformly bounded.     

The fast signal diffusion limit in a chemotaxis system with strong signal sensitivity

This paper gives an insight into making a mathematical bridge between the parabolic‐parabolic signal‐dependent chemotaxis system and its parabolic‐elliptic version. To be more precise, this paper deals with convergence of a solution for the parabolic‐parabolic chemotaxis system with strong signal sensitivity to that for the parabolic‐elliptic chemotaxis system where Ω is a bounded domain in () with smooth boundary, is a constant and χ is a function generalizing In chemotaxis systems parabolic‐elliptic systems often gave some guide to methods and results for parabolic‐parabolic systems. However, the relation between parabolic‐elliptic systems and parabolic‐parabolic systems has not been studied except for the case that . Namely, in the case that Ω is a bounded domain, it still remains to analyze on the following question: Does a solution of the parabolic‐parabolic system converge to that of the parabolic‐elliptic system as ? This paper gives some positive answer in the chemotaxis system with strong signal sensitivity.     

Boundedness of solutions to the critical fully parabolic quasilinear one‐dimensional Keller–Segel system

In this paper we consider a one‐dimensional fully parabolic quasilinear Keller–Segel system with critical nonlinear diffusion. We show uniform‐in‐time boundedness of solutions, which means, that unlike in higher dimensions, there is no critical mass phenomenon in the case of critical diffusion. To this end we utilize estimates from a well‐known Lyapunov functional and a recently introduced new Lyapunov‐like functional in 3 .     

Boundedness in a two‐species chemotaxis system

This paper is concerned with the following coupled chemotaxis system with homogeneous Neumann boundary conditions in a bounded domain Ω?Rⁿ(n≥2) with smooth boundary, where λ, χ₁, χ₂, μ₁, μ₂, a₁, a₂, b₁, and b₂ are supposed to be positive and τ = 0,1. In the case τ = 0, based on some energy estimates for both u and v, it is shown that for any parameters, the system possesses a unique globally bounded solution if n = 2. Moreover, when τ = 1, relying on a comparison principle, for a range of parameters, the existence of a unique global bounded classical solution of problem is established for any n≥2 if Ω is convex. Copyright © 2015 John Wiley & Sons, Ltd.     

Global existence of solutions for a fully parabolic chemotaxis system with consumption of chemoattractant and logistic source

This paper deals with a fully parabolic chemotaxis system with consumption of chemoattractant and logistic source under homogeneous Neumann boundary conditions in a smooth bounded domain . The functions χ and f are assumed to generalize the chemotactic sensitivity function and logistic source respectively. Under some conditions, we obtain that the corresponding initial‐boundary value problem possesses a unique global classical solution that is uniformly bounded.     

Global existence of solutions to a parabolic-parabolic system for chemotaxis with weak degradation

We study the global existence of solutions to a parabolic-parabolic system for chemotaxis with a logistic source in a two-dimensional domain, where the degradation order of the logistic source is weaker than quadratic. We introduce nonlinear production of a chemoattractant, and show the global existence of solutions under certain relations between the degradation and production orders.     

Global solutions in a fully parabolic chemotaxis system with singular sensitivity

The Neumann boundary value problem for the chemotaxis system is considered in a smooth bounded domain Ω??ⁿ, n?2, with initial data and v₀∈W^{1, ∞}(Ω) satisfying u₀?0 and v₀>0 in . It is shown that if then for any such data there exists a global‐in‐time classical solution, generalizing a previous result which asserts the same for n=2 only. Furthermore, it is seen that the range of admissible χ can be enlarged upon relaxing the solution concept. More precisely, global existence of weak solutions is established whenever . Copyright © 2010 John Wiley & Sons, Ltd.     

Global boundedness in a quasilinear chemotaxis model with nonlinear diffusion and consumption of chemoattractant

This paper proves the global existence and boundedness of solutions to a quasilinear chemotaxis model with nonlinear diffusion and consumption of chemoattractant defined on a smooth bounded domain with no‐flux boundary conditions under some assumptions. The result holds for arbitrary nonnegative sensitivity coefficients and domains in the spatial dimension which is no less than two.     

Boundedness and asymptotic stability of solutions to a two-species chemotaxis system with consumption of chemoattractant

This paper deals with a two-competing-species chemotaxis system with consumption of chemoattractant

$\{\begin{array}{cc}{u}_t=d_1\mathrm{\Delta }u?\mathrm{?}?(u{\chi }_1(w)\mathrm{?}w)+{\mu }_{1}u(1?u?a_{1}v),\hfill & x\in \mathrm{\Omega },t>0,\hfill \\ v_t=d_2\mathrm{\Delta }v?\mathrm{?}?(v{\chi }_2(w)\mathrm{?}w)+{\mu }_{2}v(1?a_{2}u?v),\hfill & x\in \mathrm{\Omega },t>0,\hfill \\ w_t=d_3\mathrm{\Delta }w?(\alpha u+\beta v)w,\hfill & x\in \mathrm{\Omega },t>0\hfill \end{array}$

under homogeneous Neumann boundary conditions in a bounded domain $\mathrm{\Omega }?{\mathbb{R}}^n$ ($n\ge 1$) with smooth boundary, where the initial data $(u_0,v_0)\in {(C^0(\stackrel{￣}{\mathrm{\Omega }}))}^2$ and $w_0\in W^{1,\infty }(\mathrm{\Omega })$ are non-negative and the parameters $d_1,d_2,d_3>0$, ${\mu }_1,{\mu }_2>0$, $a_1,a_2>0$ and $\alpha ,\beta >0$. The chemotactic function ${\chi }_i(w)$ ($i=1,2$) is smooth and satisfying some conditions. It is proved that the corresponding initial–boundary value problem possesses a unique global bounded classical solution if one of the following cases hold: for $i=1,2$,(i) ${\chi }_i(w)={\chi }_{0,i}>0$ and

${6w_{0}6}_{L^{\infty }(\mathrm{\Omega })}<\frac{\pi \sqrt{d_i{d}_3}}{\sqrt{n+1}{\chi }_{0,i}}?\frac{2\sqrt{d_i{d}_3}}{\sqrt{n+1}{\chi }_{0,i}}\arctan ?\frac{d_i?d_3}{2}\sqrt{\frac{n+1}{d_i{d}_3}};$

(ii) $0<{6w_{0}6}_{L^{\infty }(\mathrm{\Omega })}\le \frac{d_3}{3(n+1){6{\chi }_{i}6}_{L^{\infty }[0,{6w_{0}6}_{L^{\infty }(\mathrm{\Omega })}]}}\min ?\{\frac{2d_i}{d_i+d_3},1\}$.Moreover, we prove asymptotic stabilization of solutions in the sense that:? If $a_1,a_2\in (0,1)$ and $u_0\ne 0\ne v_0$, then any global bounded solution exponentially converge to $(\frac{1?a_1}{1?a_1{a}_2},\frac{1?a_2}{1?a_1{a}_2},0)$ as $t\to \infty$;? If $a_1>1>a_2>0$ and $v_0\ne 0$, then any global bounded solution exponentially converge to $(0,1,0)$ as $t\to \infty$;? If $a_1=1>a_2>0$ and $v_0\ne 0$, then any global bounded solution algebraically converge to $(0,1,0)$ as $t\to \infty$.     

Boundedness and finite-time collapse in a chemotaxis system with volume-filling effect

We consider the elliptic-parabolic PDE system

     

Absence of collapse in a parabolic chemotaxis system with signal‐dependent sensitivity

We consider the chemotaxis system under homogeneous Neumann boundary conditions in a smooth bounded domain Ω ? ?ⁿ. The chemotactic sensitivity function is assumed to generalize the prototype It is proved that no chemotactic collapse occurs in the sense that for any choice of nonnegative initial data (with some r > n), the corresponding initial‐boundary value problem possesses a unique global solution that is uniformly bounded (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)     

Large time behavior of solutions to a fully parabolic chemotaxis–haptotaxis model in N dimensions

This paper deals with the Neumann problem for a fully parabolic chemotaxis–haptotaxis model of cancer invasion given by

$\{\begin{array}{c}{u}_t=\mathrm{\Delta }u?\chi \mathrm{?}?(u\mathrm{?}v)?\xi \mathrm{?}?(u\mathrm{?}w)+u(a?\mu u^{r?1}?\lambda w),x\in \mathrm{\Omega },t>0,\hfill \\ \tau v_t=\mathrm{\Delta }v?v+u,x\in \mathrm{\Omega },t>0,\hfill \\ w_t=?vw,x\in \mathrm{\Omega },t>0.\hfill \end{array}$

Here, $\mathrm{\Omega }?{\mathbb{R}}^N(N\ge 1)$ is a bounded domain with smooth boundary and $\tau >0,r>1,\lambda \ge 0$, $a\in \mathbb{R}$, $\mu ,\xi$ and χ are positive constants. It is shown that the corresponding initial–boundary value problem possesses a unique global bounded classical solution in the cases $r>2$ or $r=2$, with $\mu >{\mu }^{?}=\frac{{(N?2)}_{+}}{N}(\chi +C_{\beta })C_{\frac{N}{2}+1}^{\frac{1}{\frac{N}{2}+1}}$ for some positive constants $C_{\beta }$ and $C_{\frac{N}{2}+1}$. Furthermore, the large time behavior of solutions to the problem is also investigated. Specially speaking, when a is appropriately large, the corresponding solution of the system exponentially decays to $({(\frac{a}{\mu })}^{\frac{1}{r?1}},{(\frac{a}{\mu })}^{\frac{1}{r?1}},0)$ if μ is large enough. This result improves or extends previous results of several authors.     

Existence and asymptotic behaviour for the time‐fractional Keller–Segel model for chemotaxis

One of the most important systems for understanding chemotactic aggregation is the Keller–Segel system. We consider the time‐fractional Keller–Segel system of order . We prove an existence result with small initial data in a class of Besov–Morrey spaces. Self‐similar solutions are obtained and we also show an asymptotic behaviour result.     

Global solutions and asymptotic behavior for a parabolic degenerate coupled system arising from biology

In this paper we will focus on a parabolic degenerate system with respect to unknown functions u and w on a bounded domain of the two dimensional Euclidean space. This system appears as a mathematical model for some biological processes. Global existence and uniqueness of a nonnegative classical Hölder continuous solution are proved. The last part of the paper is devoted to the study of the asymptotic behavior of the solutions.     

Stable and unstable manifolds for quasilinear parabolic systems with fully nonlinear boundary conditions

We investigate quasilinear systems of parabolic partial differential equations with fully nonlinear boundary conditions on bounded or exterior domains in the setting of Sobolev–Slobodetskii spaces. We establish local wellposedness and study the time and space regularity of the solutions. Our main results concern the asymptotic behavior of the solutions in the vicinity of a hyperbolic equilibrium. In particular, the local stable and unstable manifolds are constructed. Dedicated to Giuseppe Da Prato on the occasion of his 70th birthday