Mathematical Analysis for an Age-Structured Heroin Epidemic Model

In this paper, an age-structured heroin epidemic model, where the susceptibility of individuals and the relapse of heroin users in treatment are described by two age-dependent variables, is formulated and analyzed. The basic reproduction ratio of the model is derived and proved to be a threshold condition, which completely determines the global behaviors of the model. The asymptotic smoothness of the semiflow generated by the family of solutions, uniform persistence and existence of an interior global attractor have been presented for establishing and defining a Lyapunov functional on this attractor. Some control strategies of heroin and two special cases of the model formulation are addressed.

     

具有年龄结构的传染病SIR流行病模型的研究

给出美国流感监测网络统计的2008年10月至2009年9月流感症状患者数在四个年龄段的分布,结合当前H1N1新型流感发病的特点,提出一年龄结构型的流感传播模型,讨论了这个模型的应用和优点.     

Existence and Uniqueness of Endemic States for the Age-structured MSEIR Epidemic Model

The existence and uniqueness of positive steady states for the age-structured MSEIR epidemic model with age-dependent transmission coefficient is considered. Threshold results for the existence of endemic states are established; under certain conditions, uniqueness is also shown.     

On age-structured SIS epidemic model for time dependent population

1.IntroductionandPreliminaryAgestructureinepidemicmodelshasbeenconsideredbymanyauthors,becauseoftherecoghtionthattransmissiondynamicsofcertaindiseasescouldnotbecorrectlydescribedbythetraditionalepidemicmodelswithnoagedependence.Especially,Busenbergetal.II'2]giveacompleteanalysisofafairlygeneralSISmodelwithagestructureandasteady-statetotalpopulation,showingtheekistenceofathresholdforendemicstates.In[tis],theyassumethatthepopulationhasreacheditssteadystate.Althoughitisnotilladeqilatetoassumet…     

SARS数学模型解的存在唯一性与稳定性

讨论了一种带年龄结构的SARS疾病模型，它是一组非线性偏微分方程组，应用有界线性算子的C0一半群理论及非线性扰动理论，证明了该方程组非负解的存在唯一性及稳定性．     

Global asymptotic stability for an age-structured model of hematopoietic stem cell dynamics

We investigate a system of two nonlinear age-structured partial differential equations describing the dynamics of proliferating and quiescent hematopoietic stem cell (HSC) populations. The method of characteristics reduces the age-structured model to a system of coupled delay differential and renewal difference equations with continuous time and distributed delay. By constructing a Lyapunov–Krasovskii functional, we give a necessary and sufficient condition for the global asymptotic stability of the trivial steady state, which describes the population dying out. We also give sufficient conditions for the existence of unbounded solutions, which describe the uncontrolled proliferation of HSC population. This study may be helpful in understanding the behavior of hematopoietic cells in some hematological disorders.     

一类具有年龄结构的传染病模型的持续性质

研究了一类具有年龄结构的SIR型传染病模型,证明了该模型当阈值R_0<1时疾病消亡,当阈值R_0>1时模型同时具有一致弱持续性质和强持续性质.     

具有垂直传染的年龄结构SEIR流行病模型的稳定性

本文讨论了一类具有垂直传染的年龄结构SEIR 流行病模型,运用有界线性算子半群理论证明了模型本身非负解的存在唯一性.运用微分方程及积分方程中的理论和方法, 研究了该模型平衡点的稳定性,得到了无病平衡点与地方病平衡点的稳定性条件.     

An NSFD scheme for a class of SIR epidemic models with vaccination and treatment

An non-standard finite difference scheme is employed to discuss a class of SIR epidemic model with vaccination and treatment. The dynamical properties of the discretized model are then analysed. The results demonstrate that the discretized epidemic model is dynamically consistent with the continuous model since it maintains essential properties of the corresponding continuous model, such as positivity property and boundness of solutions, equilibrium points and their local stability properties.     

甲流病毒传播的年龄结构模型的稳定性

研究甲型H1N1流感病毒的传播规律,建立年龄结构具有接种措施的SEIR流行病模型,给出了疾病流行的阈值并证明了地方病平衡点的稳定性问题.最后根据一些实际数据,进行数值模拟进而对模型的合理性加以完善,借助模型预测下一阶段甲流爆发的可能性并提出相关应对措施.     

时变年龄结构的SEIR传染病模型解的存在性

本文讨论一类时变年龄结构 SEIR传染病模型 ,利用特征线、积分方程理论和泛函分析的方法证明了系统的解的存在性 ,并给出了解的表达式     

Existence and uniqueness of solutions for a hierarchical system of two age-structured populations

We propose a class of new hierarchical model for the evolution of two interacting age-structured populations, which is a system of integro-partial differential equations with global feedback boundary conditions and may describe the interactions such as competition, cooperation and predator-prey relation. Based upon a group of natural conditions, the existence and uniqueness of solutions on infinite time interval are proved by means of fixed point and extension principle, and the continuous dependence of the solution on the initial age distribution is established. These results lay a sound basis for the investigation of stability, controllability and variable optimal control problems.     

年龄结构的致命性传染病控制模型

本文在Ｂｒａｕｅｒ［１３］的基础上建立了一个致命性大范围传染病的年龄结构分布控制模型（这是一个具有非局部边界条件的偏微分方程组），证明了解的存在唯一性并分析了定常系统的非负平衡态的存在性，建立了相应的稳定性及其收敛性定理．     

一个非线性时滞偏微分方程种群模型的稳定性与周期性

讨论了一个具有年龄结构非线性非自治时滞偏微分方程种群模型解的渐近性态,得到了零解稳定以及周期解存在的充分条件.     

Convergence of numerical solutions to stochastic age-structured system of three species

In general, most of stochastic age-structured system of three species do not have explicit solutions, thus numerical approximation schemes are invaluable tools for exploring their properties. The aim of this paper is to investigate the convergence of numerical approximation solution to the true solution for stochastic age-structured system of three species.     

Bifurcation of positive equilibria in nonlinear structured population models with varying mortality rates

A parameter-dependent model involving nonlinear diffusion for an age-structured population is studied. The parameter measures the intensity of the mortality. A bifurcation approach is used to establish existence of positive equilibrium solutions.     

Numerical approximation of a stochastic age-structured population model in a polluted environment with Markovian switching

In this paper, a stochastic age-structured population model with Markovian switching is investigated in a polluted environment. Both the stochastic disturbance of environment and the Markovian switching are incorporated into the model. By Itô formula and several assumptions, the boundedness in the qth moment of exact solutions of model are proved. Furthermore, making use of truncated Euler–Maruyama (EM) method, the strong convergence criterion of numerical approximation in the qth moment is established, and the rate of convergence is estimated. Numerical simulations are carried out to illustrate the theoretical results. Our results indicate that the truncated EM method can be used for stochastic age-structured population system in a polluted environment.     

一类非线性年龄等级结构种群模型的数值解法

假设年轻个体在种群内部竞争中占优,建立一类非线性等级结构种群模型,它是具有全局耦合边界条件的偏微分-积分方程的初边值问题.提出该模型解的数值计算方法,证明算法的收敛性,并给出数值实验结果.     

具扩散的年龄结构脉冲随机时滞种群方程的均方稳定性(英文)

本文考虑一类具扩散的年龄结构脉冲随机时滞种群方程.主要目的是研究具扩散的年龄结构脉冲随机时滞种群平凡解的均方稳定性,给定两个使平凡解均方稳定的充分条件.     

Global bifurcation of positive equilibria in nonlinear population models

Existence of nontrivial nonnegative equilibrium solutions for age-structured population models with nonlinear diffusion is investigated. Introducing a parameter measuring the intensity of the fertility, global bifurcation is shown of a branch of positive equilibrium solutions emanating from the trivial equilibrium. Moreover, for the parameter-independent model we establish existence of positive equilibria by means of a fixed point theorem for conical shells.