共查询到20条相似文献,搜索用时 15 毫秒
1.
A silver-catalyzed reaction of 2-alkynylbenzaldoxime with arylsulfonyl chloride proceeds smoothly at room temperature to afford 4-tosyloxyisoquinolines in moderate to good yields. Additionally, the resulting 4-tosyloxyisoquinolines could be further elaborated through palladium-catalyzed coupling reactions leading to diverse isoquinolines. 相似文献
2.
A silver(I)-catalyzed tandem reaction of 2-alkynylbenzaldoxime with alkylidenecyclopropane gives rise to benzo-7-azabicyclo[4.2.2]dec-7-en-4-ones in moderate to good yields. The complexity and diversity could be easily incorporated with the formation of three bonds during the process. 相似文献
3.
A novel and efficient route for the synthesis of 2-(polyfluoroaryl)benzofurans via a copper(I)-catalyzed tandem reaction of 2-(2,2-dibromovinyl)phenol with polyfluoroarene is reported. The corresponding products are generated in good yields. During the reaction process, a copper-catalyzed intramolecular C-O bond formation and a C-H activation are involved. 相似文献
4.
Parallel diversity-oriented synthesis of diverse 1-(1H-imidazol-1-yl)-1,2-dihydroisoquinolines via AgOTf-catalyzed three-component reaction of 2-alkynylbenzaldehyde, amine, and imidazole is described. This reaction works efficiently under mild conditions to generate a small library of imidazole-incorporated 1,2-dihydroisoquinolines. 相似文献
5.
Hiroyuki Nakamura 《Tetrahedron letters》2008,49(17):2697-2700
Addition-cyclization of chloroform to ortho-alkynylaldimines proceeded in the presence of PdCl2(PPh3)2/dppe or Pd2dba3·CHCl3/dppe at 100 °C to afford the corresponding 1-(trichloromethyl)-1,2-dihydroisoquinolines in good to high yields. 相似文献
6.
Fuyuhiko Inagaki 《Tetrahedron》2007,63(24):5154-5160
The Rh(I)-catalyzed PKR of 1-phenylsulfonyl-1,2-octadien-7-ynes and their aza derivatives exclusively produced the corresponding 9-phenylsulfonylbicyclo[4.3.0]nona-1,6-dien-8-ones and no 4-(phenylsulfonylmethylidene)bicyclo[3.3.0]oct-1-en-3-ones could be detected. Thus, the ring-closing pattern was found to be the same as those of the previously reported 3-phenylsulfonyl-1,2-octadien-7-yne derivatives. However, the formation of 4-(phenylsulfonylmethylidene)-7-oxabicyclo[3.3.0]oct-1-en-3-ones was observed as a minor product when the 5-oxa congeners were used. In addition, a larger ring-sized product, 10-phenylsulfonyl-5-azabicyclo[5.3.0]deca-1,7-dien-9-one derivative, was obtained from the 6-aza derivative of 1-phenylsulfonyl-1,2-nonadien-8-yne. 相似文献
7.
[RhCl(COD)]2 (2 mol%) catalyzed reactions of alkenylzirconocene chloride complexes to N-Ts, -PO(OEt)2 and COOR aldimine derivatives were efficiently carried out in dioxane at room temperature to give allylic amine derivatives in excellent yields. This is the first example of the catalytic addition reactions of alkenylzirconocene chloride complexes to aldimine derivatives. 相似文献
8.
Vladislav Yu. Korotaev Igor B. Kutyashev Yurii V. Shklyaev 《Tetrahedron letters》2008,49(37):5376-5379
The basic structural framework of lamellarin alkaloids, 8,9-dihydro-6H-chromeno[4′,3′:4,5]pyrrolo[2,1-a]isoquinoline derivatives, has been obtained in good yields via Grob reaction between 3-nitro-2-(trifluoromethyl)-2H-chromenes and 1,3,3-trimethyl-3,4-dihydroisoquinolines in refluxing isobutanol. When the reaction was carried out in toluene at room temperature, only Michael adducts, as a mixture of two diastereomers, were isolated. 相似文献
9.
A three-component reaction of (E)-2-ethynylphenylchalcone, sulfonyl azide, and amine catalyzed by copper(I) chloride (5 mol%), in the presence of triethylamine, under mild conditions is described. This transformation proceeds efficiently to generate 1,2-dihydroisoquinolin-3(4H)-imines in good to excellent yields. 相似文献
10.
O. G. Yarosh L. V. Shchukina L. V. Sherstyannikova M. G. Voronkov 《Russian Chemical Bulletin》1985,34(11):2444-2446
Conclusions The reaction of trimethyl(bromomagnesiumethynyl)silane with organyltrialkoxysilanes gave a series of organyl(trimethylsilylethynyl)dialkoxysilanes.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 11, pp. 2637–2640, November, 1985. 相似文献
11.
Nataliya V. Kirij Valeria N. Movchun Wieland Tyrra Hendrik T.M. Fischer 《Journal of fluorine chemistry》2008,129(1):14-21
The reactions of non-activated aldimines with trimethyl(trifluoromethyl)silane and 1 equiv. of tetramethylammonium fluoride proceed via the formation of tetramethylammonium amides which were identified by low-temperature 19F NMR experiments. Consecutive reactions of the salts formed in situ with electrophiles yielded trifluoromethylated amines. Fluoride elimination is observed in the absence of electrophilic substrates leading to the formation of difluoromethylated ketimines. 相似文献
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14.
V. Ya. Sosnovskikh B. I. Usachev M. N. Permyakov D. V. Sevenard G.-V. Röschenthaler 《Russian Chemical Bulletin》2006,55(9):1687-1689
Condensation of 2-trifluoromethylchromone with diethyl malonate, ethyl cyanoacetate, and Meldrum’s acid gave the corresponding
methylidene derivatives of 2-trifluoromethyl-4H-chromene. Nucleophilic 1,6-addition of an excess of Me3SiCF3 in the presence of Me4NF to those obtained from the former two compounds afforded 4-substituted 2,2-bis(trifluoromethyl)-2H-chromenes.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 9, pp. 1628–1630, September, 2006. 相似文献
15.
Novel Ru2-containing dendritic compounds were prepared from the CuI-catalyzed 1,3-dipolar cycloaddition between Ru2 compounds containing one or two ethynes, Ru2(D(3,5-Cl2Ph)F)4-n(DMBA-4-C2H)n with n=1 and 2, and azidopoly(benzyl ether) dendrons. These new compounds were also characterized with X-ray diffraction and voltammetric techniques. 相似文献
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17.
Being able to increase the yield by >20% compared to the conventional use of anhydrous zinc chloride (>1 equiv) as a promoter, Ph 3PAuOTf is disclosed to be a superior catalyst for the well-established glycosylation reaction with 1,2-anhydrosugars as donors. 相似文献
18.
Daiki Monguchi 《Tetrahedron letters》2010,51(5):850-12878
When several azole derivatives such as imidazole, thiazole, and oxazole are treated with a catalyst system of copper(II)/silver(I) under oxygen atmosphere, oxidative dimerization at the CH bond of the 2-position takes place to afford the corresponding bisazoles up to 86% yield. 相似文献
19.
A cascade reaction of 2-ethynylaryl methylenecyclopropane with sulfonyl azide catalyzed by copper(I) iodide under mild conditions is described, which provides a novel and efficient route for the generation of fused indolines. 相似文献
20.
The total synthesis of (+)-asteriscanolide starting from two commercially available materials has been accomplished in 19 steps with a 3.8% overall yield. The key reaction is a chiral ene-vinylcyclopropane substrate induced Rh(I)-catalyzed [(5+2)+1] cycloaddition that efficiently constructs the [6.3.0] carbocyclic core with complete asymmetric induction. 相似文献