New ionic liquids with the bis[bis(pentafluoroethyl)phosphinyl]imide anion, [(C2F5)2P(O)]2N—Synthesis and characterization

A new series of low melting and hydrophobic ionic liquids (ILs) containing the bis[bis(pentafluoroethyl)phosphinyl]imide anion, [(C₂F₅)₂P(O)]₂N⁻ (FPI), and ammonium, phosphonium, imidazolium, pyridinium or pyrrolidinium cations were prepared and characterized. Their density, viscosity, melting point, glass transition temperature, decomposition temperature and conductivity are discussed. Many of these ionic liquids are liquids at room temperature with melting points below 15 °C, viscosities below 110 mm² s⁻¹ and thermal stabilities above 300 °C.     

Synthesis of (S)-2-amino-7-methoxytetralin and isoindolo[1,2-a]isoquinolinone derivatives from l-aspartic acid

This paper describes a new total synthesis for (S)-2-amino-7-methoxytetralin, (S)-7-MeO-AT, from l-aspartic acid in an overall yield of 10% over nine steps. The major loss was ascribed to a key intramolecular Friedel–Crafts cyclization step, which afforded up to 36% yield. Attempts to perform a Friedel–Crafts cyclization of an intermediate phthalimide protected amino alcohol 13 did not give the desired protected (S)-7-MeO-AT. On the other hand, two new isoindolo[1,2-a]isoquinolinone derivatives 14 and 15, were isolated in 21 and 11% yield, respectively. The yield of 15 was improved to 70%.     

Bi(OTf)3/[bmim]BF4 as novel and reusable catalytic system for the synthesis of furan, pyrrole and thiophene derivatives

Bi(OTf)₃ immobilized in 1-butyl-3-methylimidazolium tetrafluoroborate [bmim]BF₄ has been utilized for the first time as a novel and reusable catalytic system for the synthesis of heteroaromatics such as furan, pyrrole and thiophene derivatives from 1,4-diketones. This new procedure offers significant improvements in reaction rates and yields. The recovered ionic liquid containing bismuth triflate can be reused for subsequent runs with only a gradual decrease in activity.     

酸性离子液体催化合成三吲哚甲烷化合物

在酸性离子液体催化下,通过吲哚及其衍生物和吲哚甲醛反应合成了一系列三吲哚甲烷化合物。[hmim]HSO₄/EtOH 对于该反应来说,是一个高效、绿色的催化体系。     

A novel sulfonic acid functionalized ionic liquid catalyzed multicomponent synthesis of 10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione derivatives in water

Three-component reactions of 4-hydroxycoumarin, aldehydes, and cyclic 1,3-dicarbonyl compounds were prompted by novel sulfonic acid functionalized ionic liquids 1,3-dimethyl-2-oxo-1,3-bis(4-sulfobutyl)imidazolidine-1,3-diium hydrogen sulfate ([DMDBSI]·2HSO₄) in water at reflux temperature to provide a novel series of 10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione derivatives for the first time in high yields.